Nervous System Cells TRIZ Cases
- Spinal Cord Neural Stem Cell Generation via Morphogen Patterning
Culturing human pluripotent stem cells with caudalizing morphogens and SMAD inhibitors to generate spinal cord neural stem cells.
- Sustainable Biomaterials from Tunicates and Fish Skin for Bioprinting
Tunicate extracellular matrix and fish skin collagen replace costly mammalian sources to reduce environmental harm while maintaining cell proliferation.
- Microwell Curved Surface for Inner Ear Organoid Uniformity
Curved microwells guide stem cell aggregation into uniform spheroids, addressing the difficulty of replicating inner ear structure in hearing loss models.
- Neuronal Cell Isolation via CD51 Negative Selection
CD51 negative selection isolates living neuronal cells using magnetic beads to label non-neuronal contaminants.
- Brain Pericyte-Like Cell Differentiation Protocol
Differentiating human pluripotent stem cells into brain pericyte-like cells resolves scalability and marker expression contradictions for BBB models.
- Virtual Electrowetting Microdroplet Manipulation for Cell Screening
Virtual electrowetting electrodes replace physical structures to resolve the contradiction between manipulation flexibility and device complexity.
- Differentiation-Promoted Pluripotent Stem Cell Culture Medium
A culture medium containing GSK3β, BMP, and TGF-β inhibitors induces pluripotent stem cells into a differentiation-promoted state.
- KU-60019 Accelerates Cell Maturation for Neurodegenerative Disease Modeling
KU-60019 accelerates cell maturation to reveal neurodegenerative phenotypes within seven days, bypassing the decades required for natural aging.