Macrocyclic Picolinamides for Broad-Spectrum Fungal Control
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Solution Overview
Problem
Current fungicides are not universally effective against various fungal pathogens and often require multiple applications, which can be costly and complex to use.
Innovation Solution
Development of macrocyclic picolinamides as fungicides that provide protection against ascomycetes, basidiomycetes, deuteromycetes, and oomycetes, formulated with phytologically acceptable carriers for application on plants, seeds, or soil to prevent fungal attacks.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If multiple different fungicides are used to control various fungal pathogens, then the coverage of fungal types is improved, but the complexity of application and cost increase
Solution Approach 1:
The patent develops a single fungicidal compound (macrocyclic picolinamide) that can control multiple types of fungi including ascomycetes, basidiomycetes, deuteromycetes, and oomycetes. This multi-functional approach eliminates the need to use multiple different fungicides for different fungal pathogens, thereby reducing application complexity while maintaining broad spectral coverage.
2Reliability
If multiple fungicide applications are made to ensure effective protection, then the fungal control reliability is improved, but the number of applications and cost increase
Solution Approach 1:
The patent employs fungicidal compounds with long residual activity that continue to protect plants against fungal pathogens over extended periods. This continuous protective action reduces the frequency of re-application needed, thereby reducing time loss and application costs while maintaining reliable fungal control.
3Adaptability or versatility
If broad-spectrum fungicides are used to control multiple fungal types, then the adaptability is improved, but the phytotoxicity risk increases
Solution Approach 1:
The patent modifies the chemical structure of picolinamide compounds by introducing specific macrocyclic structures and substituent groups (such as alkyl, alkoxy, halogen, and aryl groups at various positions). These structural parameter changes optimize the compounds to achieve broad-spectrum fungicidal activity against multiple fungal types while reducing phytotoxicity to plants through careful tuning of molecular properties.
Data Source
AI summary
The disclosure relates to macrocyclic picolinamides of Formula (I) and to the use of these compounds as fungicides. The present disclosure also includes a fungicidal composition for the control or prevention of fungal attack comprising the macrocyclic picolinamides of Formula (I) and a phytologically acceptable carrier material. A method is also described for the control or prevention of fungal attack on a plant, including the steps of applying a fungicidally effective amount of one or more of the macrocyclic picolinamides of Formula (I) to at least one of the fungus, the plant, an area adjacent to the plant, and the seed adapted to produce the plant.