Microarray Substrate Vapor Deposition for Uniform Monolayers

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Solution Overview

Problem

The existing methods for manufacturing microarray substrates with self-assembled monolayers face challenges in achieving uniformity and reliability due to difficulties in controlling the concentration of functional group layer materials, particularly in the dipping method where concentration varies with position and time, limiting mass-production properties.

Innovation Solution

A method involving the use of a vapor of a surface-reforming material is employed to form a self-assembled monolayer on a base substrate, where the vapor is supplied through a bubbler with an inert gas, maintaining a constant concentration and adjusting temperature and flow rate to control the self-assembled monolayer properties, and an apparatus is designed to facilitate this process with a gas distributor and discharge portion to ensure uniform coverage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If the dipping method is used to form the functional group layer, then the self-assembled monolayer can be formed on the substrate, but the concentration of the functional group layer material varies with position and time, resulting in poor uniformity and reliability

Engineering Contradiction:
Improveuniformity of self-assembled monolayerVSAvoidreliability of microarray substrate
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The patent changes the physical state of the functional group layer material from liquid (dipping method) to vapor phase. By controlling the vapor concentration through parameters such as temperature, pressure, and flow rate, the patent achieves uniform deposition of the self-assembled monolayer across the substrate surface, eliminating the concentration variation problem inherent in the dipping method

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the mechanical dipping process with a vapor-phase deposition process. Instead of immersing the substrate in liquid solution where concentration varies with position and time, the substrate is exposed to controlled vapor flow, enabling uniform and reliable formation of the functional group layer

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If multiple process steps are performed to manufacture the microarray substrate, then the self-assembled monolayer can be formed, but the manufacturing complexity increases and mass-production properties are limited

Engineering Contradiction:
Improvequality of self-assembled monolayerVSAvoidnumber of process steps
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent combines the formation of the self-assembled monolayer with the substrate manufacturing process by integrating vapor-phase deposition into a single continuous step. This merging of processes eliminates the need for separate dipping, drying, and concentration control steps, thereby reducing manufacturing complexity while maintaining high quality

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The vapor-phase deposition process allows for continuous and uniform deposition of the functional group layer material across the substrate surface. The continuous vapor flow ensures consistent material supply and reaction conditions, eliminating the intermittent nature of dipping processes and enabling efficient mass production

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the consistent formation of self-assembled monolayers with improved reliability and mass-production capabilities, enabling the production of microarray substrates with uniform properties regardless of time or position, and simplifies the control of process conditions.

Implementation Method 1

supplying a vapor of a surface-reforming material into a container to which the base substrate is provided, and coupling the vapor of the surface-reforming material to a surface of the base substrate to form a self-assembled monolayer

Methodology Applied
Scientific EffectVapor phase deposition: Chemical Vapour Deposition

Implementation Method 2

supplying an inert gas into a bubbler receiving the surface-reforming material in a liquid phase to move the vapor of the material of the self-assembled monolayer by the inert gas

Methodology Applied
Scientific EffectGas flow transport: Convection

Implementation Method 3

the bubbler may be heated to a temperature between room temperature and a boiling point of the surface-reforming material

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS9783893B2Method of manufacturing micro-array substrate
Publication Date: 2017.10.10 GACHON UNIV OF IND ACADEMIC COOPERATION FOUND
  • US9783893B2 patent drawing
  • US9783893B2 patent drawing
  • US9783893B2 patent drawing

AI summary

A method of manufacturing a microarray substrate having improved reliability and mass-production properties uses a vapor of a surface-reforming material, and includes washing a base substrate, supplying the vapor of the surface-reforming material into a container to which the base substrate is provided, and coupling the vapor of the surface-reforming material to a surface of the base substrate to form a self-assembled monolayer.