Microbial Casein Production Using Lactoserum Carbon Source

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Solution Overview

Problem

The dairy industry faces challenges related to health, environmental, and ethical concerns, including lactose intolerance, high saturated fatty acid content, greenhouse gas emissions, water consumption, pollution, and animal welfare issues. There is a need for dairy product substitutes that are free from undesired compounds, similar to traditional dairy products in terms of aspect, texture, and taste, and equivalent or superior in nutrition.

Innovation Solution

The use of lactoserum as a carbon source for culturing microorganisms expressing caseins, particularly during fed-batch culture, reduces the environmental footprint compared to using glucose, sucrose, or sucrose molasses. This method involves fermenting microorganisms with lactoserum, which induces casein production and allows for the recycling of waste materials, thereby reducing environmental impact.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional dairy products are produced from animal milk, then nutritional quality and taste are improved, but environmental footprint and ethical concerns worsen

Engineering Contradiction:
Improvenutritional qualityVSAvoidenvironmental footprint
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent produces casein proteins through microbial fermentation that replicate the structure and function of natural milk casein. The microorganisms are engineered to express casein genes, creating a copy of the desired protein without requiring animal milk, thus maintaining nutritional quality while eliminating environmental harm from animal farming

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent converts lactoserum, a waste byproduct from cheese production, into a valuable carbon source for microbial fermentation. This transforms an environmental burden (waste disposal) into a beneficial resource that drives casein production, reducing overall environmental footprint while maintaining protein quality

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Object-generated harmful factors

If lactoserum is used as carbon source for casein production, then environmental footprint is reduced, but production cost and process complexity may increase

Engineering Contradiction:
Improveenvironmental footprintVSAvoidprocess complexity
Core Design Contradiction:
Object-generated harmful factorsVSDevice complexity

Solution Approach 1:

The patent recovers and reuses lactoserum, a discarded byproduct from cheese making, as a carbon source for microbial fermentation. This recovery process transforms waste into a valuable resource, reducing environmental impact while integrating smoothly into existing dairy production workflows

Inventive Principle:
Principle #34Discarding and recovering

Solution Approach 2:

The system creates a self-sustaining cycle where waste from cheese production (lactoserum) automatically becomes the fuel for producing casein, which can then be used to create dairy alternatives. The process serves itself by using its own waste products, reducing the need for external resources and simplifying overall system complexity

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach results in a reduced environmental footprint, including lower greenhouse gas emissions, improved water usage, and reduced pollution, while providing a viable method for recycling dairy industry waste. Additionally, it enables the production of dairy substitutes that are nutritionally equivalent or superior to traditional dairy products.

Implementation Method 1

The use of lactoserum as a carbon source for culturing microorganisms expressing caseins, particularly during fed-batch culture

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

heating the microorganism composition so as to reduce the amount of the other proteins in soluble fraction of the composition

Methodology Applied
Scientific EffectThermal denaturation: Heat Treatment

Data Source

PatentEP4533954A1Method for producing casein and uses thereof
Publication Date: 2025.04.09 STANDING OVATION
  • EP4533954A1 patent drawingFigure 1~2a
  • EP4533954A1 patent drawingFigure 2b~2c
  • EP4533954A1 patent drawingFigure 2d~2e

AI summary

The invention pertains to the food industry and relates to new methods for producing casein compositions by culturing transgenic microorganisms in presence of lactoserum, and limiting the environmental footprint.