Microneedle Patch Adhesive Composition for Clean Needle Removal
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Solution Overview
Problem
Existing microneedle patches leave the microneedle array on the skin when peeled off, which is undesirable.
Innovation Solution
A microneedle patch with an adhesive layer containing a water-soluble polymer and water, having a loss tangent of 0.20 to 0.41, ensures the microneedle array is not left on the skin upon removal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If the adhesive layer has strong adhesion to hold the microneedle array, then the microneedle array remains on the skin during application, but the microneedle array cannot be completely removed when peeled off
Solution Approach 1:
The invention changes the physical-chemical parameters of the adhesive layer by controlling the loss tangent to be 0.05 to 0.20, which optimizes the balance between adhesion strength and removability. This parameter adjustment allows the adhesive to hold the microneedle array firmly during application while enabling complete removal when peeled off, resolving the contradiction between strong adhesion and ease of removal.
2Ease of operation
If the adhesive layer uses a water-soluble polymer to enable easy removal, then the patch can be peeled off cleanly, but the adhesion strength may be insufficient to hold the microneedle array
Solution Approach 1:
The invention adjusts the loss tangent parameter of the water-soluble polymer adhesive layer to fall within the specific range of 0.05 to 0.20. This parameter optimization ensures that the adhesive maintains sufficient strength to hold the microneedle array during application while remaining easy to remove completely when peeled off, thus resolving the contradiction between removal ease and adhesion strength.
3Strength
If the loss tangent of the adhesive layer is increased to improve adhesion, then the microneedle array adheres better, but the microneedle array may remain on the skin after peeling
Solution Approach 1:
The invention precisely controls the loss tangent of the adhesive layer to be within the range of 0.05 to 0.20. This parameter optimization prevents the adhesive from being too strong, which would cause microneedle residue on the skin, while still maintaining sufficient adhesion to hold the microneedle array during application. This resolves the contradiction between adhesion strength and prevention of microneedle residue.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The patch effectively adheres to the skin without leaving the microneedle array behind, ensuring easy and complete removal.
Implementation Method 1
an adhesive layer provided on the main surface of the backing
Implementation Method 2
the adhesive layer includes a water-soluble polymer and water
Data Source
Figure 1
Figure 2
AI summary
A microneedle patch according to one example includes a backing, an adhesive layer provided on the main surface of the backing, and a microneedle array at least a part of which is positioned within the adhesive layer, wherein the adhesive layer includes a water-soluble polymer and water, and a loss tangent of the adhesive layer under measurement conditions of an environmental temperature of 25°C and a frequency of 1 Hz is 0.20 to 0.41.