Microneedle Patch Protective Release Sheet with Cutting Lines

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Solution Overview

Problem

The application of microneedle patches with flexible substrates poses a risk of contamination due to the difficulty in removing the protective release sheet without contacting the adhesive face and microneedles, as conventional methods are not suitable for bending the substrate to expose the microneedle patch for skin application.

Innovation Solution

A protective release sheet with a hole and cutting lines is designed, allowing for the microneedle patch to be easily removed by pinching the cutting lines and bending the patch outward, while an interspace between the sheet and array prevents damage and contamination, with the hole size tailored to accommodate the microneedle array and adhesive tape.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the protective release sheet is attached to the whole surface of the adhesive agent, then the microneedle patch is protected during storage and transport, but the microneedle cannot be easily removed without contacting the adhesive face and microneedles

Engineering Contradiction:
Improveprotection of microneedle patchVSAvoidremoval of protective release sheet
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The protective release sheet is divided into multiple sections by providing cutting lines that extend from the peripheral edge to the hole. This segmentation allows users to grasp and pull the sheet from the edges without exposing the microneedle array, enabling easy removal while maintaining protection.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A hole is provided in the protective release sheet to expose the microneedle array while keeping the adhesive face covered. This extraction allows the microneedle patch to be applied to the skin without requiring removal of the entire protective sheet, eliminating the need to contact the adhesive face or microneedles during application.

Inventive Principle:
Principle #2Taking out (Extraction)

2Adaptability or versatility

If the substrate is made flexible to facilitate application, then the patch can be bent and applied to skin, but the substrate becomes more susceptible to damage during handling

Engineering Contradiction:
Improveflexibility of substrateVSAvoiddurability of substrate
Core Design Contradiction:
Adaptability or versatilityVSStrength

Solution Approach 1:

The protective release sheet acts as a cushioning layer that protects the flexible substrate from damage during handling and application. By providing a protective covering that can be easily removed through the cutting lines and hole design, the substrate is shielded from mechanical damage while maintaining its flexibility for skin application.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

3Ease of operation

If the hole size is made large to accommodate the microneedle array, then the array is fully exposed, but the adhesive face is exposed and may be contacted during removal

Engineering Contradiction:
Improveexposure of microneedle arrayVSAvoidcontamination of adhesive face and microneedles
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The hole is precisely sized to extract only the necessary portion of the protective release sheet for application, while the adhesive face remains covered. This precise extraction allows the microneedle array to be exposed and applied to the skin without requiring removal of the entire protective sheet, preventing contamination of the adhesive face and microneedles during the application process.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS11998712B2Protective release sheet for microneedle patch
Publication Date: 2024.06.04 COSMED PHARMA
  • US11998712B2 patent drawing
  • US11998712B2 patent drawing
  • US11998712B2 patent drawing

AI summary

Provided is a microneedle patch which is easily to be applied on a skin surface. One or more holes are provided inside a protective sheet of the microneedle patch, and one or more cutting lines running from an outer edge of the protective sheet toward the holes are also provided. The cutting lines may be symmetrically arranged on both sides of the hole. Providing an incision on the outer edge of the cutting lines of the protective release sheet facilitates cutting along the cutting lines. In the use of the microneedle patch, both sides of the cutting line of the protective release sheet are held and torn so as to bring out a microneedle array adhesive sheet and apply it on a skin. Then the microneedle array surface is slightly compressed, thereby the microneedle is inserted into the stratum corneum.