A transdermal microneedle device uses a pushing element to apply continuous bilateral force for consistent skin penetration.
Segmenting the tip into sharp points and a cutting edge reduces tissue resistance, enabling reliable penetration through the epithelium barrier.
Microstructures penetrate skin to mechanically grasp tissue, eliminating adhesive failure from moisture and reducing scarring.
A handheld device generates a pressurized fluid stream to penetrate human skin or mucosa for compound delivery.
Microneedles bypass the melanin barrier to deliver UV-B light directly to dermal cells, ensuring reliable vitamin D synthesis across all skin tones.
A microneedle sensor design merges reference and counter electrodes onto a single panel substrate while inserting reaction electrodes into hollow needle channels.
A two-layer molding process creates needle-like array sheets by bonding distinct resin layers in separate stages.
A transdermal delivery system uses electrical discharge to create micropores in the stratum corneum for controlled drug transport.
A biodegradable microneedle with a two-step structure and specific corner angle.
Segmented microneedles with insulated shafts create focused electroporation pores, enabling high-throughput drug transport while preserving skin integrity.
Asymmetric radial microneedles deform skin independently during puncture, eliminating extra mechanisms and reducing device size.
Step formations prevent capillary movement, ensuring quantitative drug delivery and high usage efficiency.
A linear surgical stapler cartridge integrates resorbable microneedles to deploy therapeutic agents into tissue layers alongside staples.