Pressurized Fluid Delivery Device for Transdermal Compound Absorption
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Solution Overview
Problem
Current methods for delivering compounds, such as psychedelics and cannabinoids, into the human body are limited in bioavailability and often rely on invasive techniques like needle syringes, which can be inefficient and uncomfortable.
Innovation Solution
A delivery system using a pressurized stream of fluid, targeted at the skin or mucosa, which may include encapsulation in liposomes or micelles, and optional preconditioning methods like heat, vibration, or vacuum sealing to enhance absorption, utilizing a hand-held device with adjustable pressure and nozzle size for increased bioavailability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional needle syringe method is used for delivering compounds into the human body, then delivery can be achieved, but the method is invasive and has limited bioavailability
Solution Approach 1:
The patent replaces the mechanical needle injection system with a fluid dynamic system using pressurized streams. The delivery mechanism transitions from solid needle penetration to fluid stream interaction with the skin surface, utilizing hydrodynamic forces to achieve compound delivery without invasive penetration.
Solution Approach 2:
The invention employs pressurized fluid streams (hydraulic principle) to deliver compounds through the skin. The system uses controlled pressure application through fluid dynamics to achieve transdermal or transmucosal delivery, replacing the mechanical injection approach with a pneumatic-hydraulic delivery mechanism.
2Reliability
If standard application methods are used for compound delivery, then simplicity is maintained, but bioavailability is limited
Solution Approach 1:
The patent applies preliminary conditioning to the skin or mucosa before compound delivery. Steps such as heat application, vibration, or chemical preparation are performed in advance to enhance skin permeability and prepare the delivery site, thereby improving subsequent compound absorption and overall bioavailability.
Solution Approach 2:
The system utilizes adjustable parameters including pressure levels, stream radius, and application duration to optimize delivery. The device allows modification of fluid stream characteristics and environmental conditions (temperature, pressure) to enhance penetration efficiency and control delivery rates, thereby improving bioavailability through parameter optimization.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method significantly increases bioavailability by up to 300% compared to traditional application methods, providing a non-invasive, efficient, and user-friendly delivery of compounds, with adjustable settings for optimal absorption.
Implementation Method 1
providing a delivery device configured to provide a pressurized stream of fluid... penetrating the user's skin or mucosa via the pressurized stream of fluid
Implementation Method 2
the compounds, chemicals, or nutrients are configured to be encapsulated in a liposome, micelle, or phospholipid to increase absorption
Implementation Method 3
a step of applying heat at a temperature to the location to increase absorption
Implementation Method 4
a step of applying vibration to the location to increase absorption
Implementation Method 5
a step of applying chemicals to the location to increase absorption
Implementation Method 6
the delivery device comprises a vacuum disk configured to create a vacuum seal on the human body... creating a vacuum seal at the location to increase absorption
Data Source
AI summary
A method for delivering matter into a human body is provided via a manual or automatic hand-held delivery device configured to provide a pressurized stream of fluid. The fluid contains compounds, chemicals, nutrients, vitamins or other desired matter. A user, via the device, is configured to target the pressurized stream of fluid to a location on the human body, e.g. the user's skin or mucosa. The pressurized stream is configured to penetrate the user's skin or mucosa such that at least a portion of the fluid is absorbed into the user's skin or mucosa. Various preconditioning methods are provided to increase the absorption rate and bioavailability.