Microneedle Array Device with Recessed Deployment Mechanism
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Solution Overview
Problem
Existing methods for applying microneedle arrays to the skin face challenges in effectively inserting needles to a desired depth and protecting delicate microneedles prior to application, limiting the transport of therapeutic molecules through the skin.
Innovation Solution
A device with a base and a microneedle array component connected by flexible members that can move from a recessed position to a skin-contacting position, using a mechanical applicator to apply force and align the microneedle array for precise penetration, while maintaining the microneedles' integrity and alignment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If microneedles are made delicate to minimize skin damage, then skin penetration capability is improved, but protection of microneedles prior to application becomes more difficult
Solution Approach 1:
The microneedle array is recessed within a protective well or cavity in the base structure. This nesting arrangement protects the delicate microneedles from damage during storage and handling while allowing them to be deployed for skin penetration when needed.
Solution Approach 2:
The microneedle array is made movable relative to the base, transitioning from a recessed protected position to an extended skin-contacting position. This dynamic configuration allows the microneedles to be protected when not in use and deployed when needed for penetration.
2Object-affected harmful factors
If microneedles are inserted to greater depth to overcome stratum corneum barrier, then therapeutic agent delivery is improved, but risk of microneedle breakage increases
Solution Approach 1:
The microneedles are designed to be movable, extending from a recessed position to a skin-contacting position where they can penetrate the stratum corneum to the desired depth. This dynamic deployment allows controlled penetration depth while maintaining microneedle integrity through proper positioning and force application.
Solution Approach 2:
The microneedles are pre-positioned in a recessed state within the device, allowing them to be protected and aligned before application. This preliminary positioning ensures they are ready for controlled insertion at the correct depth without risk of breakage during handling.
3Ease of operation
If microneedle array is kept exposed for easy application, then ease of operation is improved, but microneedles are more susceptible to damage
Solution Approach 1:
The microneedle array is designed to be movable between a recessed protected position and an extended skin-contacting position. This dynamic design allows the microneedles to be protected during storage and handling while being easily deployed for application when needed.
Solution Approach 2:
The microneedle array is nested within a protective structure when not in use, shielding them from damage. When application is needed, the microneedles can be easily extended from this protected position, maintaining both protection and ease of operation.
Data Source
AI summary
A device (100) for applying a microneedle array to a skin surface. The device comprises a base (120) defining a skin contacting plane, an array component having a skin facing side comprising a microneedle array, and at least one connecting member (140) having a first portion affixed through a first hinge (142) to the base and a second portion affixed to the array component. The connecting member has a first equilibrium position with the microneedle array in a recessed position within the device and a second equilibrium position with the microneedle array positioned so as to be able to contact a skin surface.