Multi-Stimulation Engine Circuit for Collision-Free Neuromodulation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing implantable pulse generators (IPGs) face challenges in efficiently delivering multiple stimulation therapies without channel contention or electrical collisions, particularly when multiple stimulation engines require simultaneous usage of the same electrodes or different voltage multiplier settings.

Innovation Solution

The implementation of an implantable medical device (IMD) with multiple stimulation engines (SEs) and selectively connectable power supply circuitry, featuring a voltage multiplier (VM), switching circuitry, and digital control logic to independently control each SE, allowing independent stimulation or discharge of electrode sets without channel contention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If multiple stimulation engines share a common voltage multiplier, then device complexity is reduced, but channel contention and electrical collisions occur when multiple engines require simultaneous usage of the same electrodes or different voltage settings

Engineering Contradiction:
Improvedevice complexityVSAvoidchannel contention
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The system segments the voltage multiplier functionality by providing separate voltage multiplier circuits for each stimulation engine. This allows each engine to have dedicated voltage generation capabilities, eliminating channel contention when multiple engines operate simultaneously with different voltage requirements. The segmentation of power supply architecture resolves the conflict between shared resources and independent control.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces switching circuitry as an intermediary component that manages power distribution between multiple stimulation engines. The switching circuitry acts as a mediator that can selectively connect different voltage multipliers to different engines based on operational requirements, preventing electrical collisions while maintaining system coordination.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If multiple stimulation engines operate independently, then simultaneous delivery of multiple therapies is enabled, but device complexity and power consumption increase

Engineering Contradiction:
Improvesimultaneous therapy deliveryVSAvoiddevice complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

Each stimulation engine is designed as a universal module capable of delivering multiple therapy types through independently controllable electrode configurations. The engines can be selectively activated based on therapeutic needs, providing multi-functionality at the engine level while maintaining a standardized architecture that reduces overall system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system employs dynamic control through switching circuitry that can selectively activate or deactivate individual stimulation engines based on real-time therapeutic requirements. This dynamic configuration allows the system to adapt between single-engine and multi-engine operation modes, balancing versatility with power consumption and device complexity.

Inventive Principle:
Principle #15Dynamics

3Use of energy by moving object

If a single voltage multiplier is used for all stimulation engines, then power efficiency is improved, but electrical collisions occur when engines require different voltage settings simultaneously

Engineering Contradiction:
Improvepower efficiencyVSAvoidelectrical collisions
Core Design Contradiction:
Use of energy by moving objectVSReliability

Solution Approach 1:

The power supply architecture is segmented into multiple independent voltage multiplier circuits, each dedicated to a specific stimulation engine. This segmentation eliminates electrical collisions by providing isolated voltage generation paths, allowing each engine to operate with its required voltage settings without interfering with other engines.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system implements independent voltage parameter control for each stimulation engine through dedicated voltage multipliers. Each engine can operate with optimized voltage parameters specific to its therapeutic function, eliminating the need to compromise voltage settings due to shared resource constraints.

Inventive Principle:
Principle #35Parameter changes

4Volume of moving object

If stimulation engines share common power supply circuitry, then device size is reduced, but channel contention prevents simultaneous operation of multiple therapies

Engineering Contradiction:
Improvedevice sizeVSAvoidsimultaneous therapy operation
Core Design Contradiction:
Volume of moving objectVSAdaptability or versatility

Solution Approach 1:

The power supply circuitry is segmented into multiple independent voltage multiplier units, each assigned to a specific stimulation engine. This segmentation enables simultaneous operation of multiple therapies by providing dedicated power paths, while the modular architecture keeps individual component sizes small, allowing compact integration within the implantable device.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system employs a nested modular architecture where multiple stimulation engines with their associated voltage multipliers are integrated within a compact implantable housing. The nested structure allows multiple functional units to be packed efficiently, maintaining small overall device size while enabling simultaneous multi-therapy operation through independent engine control.

Inventive Principle:
Principle #7Nested doll (Nesting)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables simultaneous delivery of multiple stimulation therapies to different areas of the patient's tissue without channel collisions, providing flexible and efficient stimulation settings for spinal cord stimulation (SCS), neuromuscular, deep brain stimulation (DBS), and other therapies.

Implementation Method 1

a voltage multiplier (VM) configured to generate an adjustable target voltage at an output node based on a voltage supplied by the power supply

Methodology Applied
Scientific EffectVoltage multiplication:

Implementation Method 2

first switching circuitry to switchably connect an anodic node of the SE to a VM connection node driven by the output node and second switching circuitry to switchably connect a cathodic node of the SE to a current sink circuit

Methodology Applied
Scientific EffectElectrical switching:

Implementation Method 3

Discharge switching circuitry may be disposed between the anodic and cathodic nodes of each SE

Methodology Applied
Scientific EffectElectrical discharge: Electrostatic Discharge

Implementation Method 4

a current sink circuit switchably coupled to the cathodic node; second switching circuitry configured to actuate switchable coupling between the current sink circuit and the cathodic node

Methodology Applied
Scientific EffectCurrent sinking:

Data Source

PatentEP4103266B1Neuromodulation therapy with a multiple stimulation engine system
Publication Date: 2026.01.21 ADVANCED NEUROMODULATION SYSTEMS INC
  • EP4103266B1 patent drawingFigure 1A
  • EP4103266B1 patent drawingFigure 1B
  • EP4103266B1 patent drawingFigure 2

AI summary

An implantable medical device (IMD) (102, 150) includes multiple stimulation engines (SEs) (402-i) for independently stimulating respective electrode sets of a lead system (106A/B, 186). A voltage multiplier (VM) (302) is configured to generate an adjustable target voltage at an output node (304). Each stimulation engine (402-i) includes first switching circuitry (452) to switchably connect an anodic node (456) of the SE (402-i) to a VM connection node (450) driven by the output node (304) and second switching circuitry (434) to switchably connect a cathodic node (458) of the SE (402-i) to a current sink circuit (422). Discharge switching circuitry (472) may be disposed between the anodic and cathodic nodes (456, 458) of each SE (402-i). A selector (408) and associated digital control logic block (404) are operative to generate control signals (405A, 405B) for independently controlling respective SEs (402-i) such that each SE may be activated to stimulate or discharge a corresponding select set of electrodes (412) independently from or in concert with remaining SEs.