Mycotoxin Adsorbent Composition Using Phyllosilicates and Charcoal

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Solution Overview

Problem

Current solutions fail to effectively adsorb deoxynivalenol (DON) mycotoxin without interfering with essential nutrients and are not proven to be non-toxic at therapeutic doses, posing challenges in animal feed formulations.

Innovation Solution

A compound comprising a mixture of magnesium phyllosilicate (19-75% by weight), aluminium phyllosilicate (25-85% by weight), and activated vegetable charcoal (1-10% by weight), specifically designed to adsorb mycotoxins like DON, with a synergistic effect enhancing adsorption efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional adsorbents are used to adsorb DON, then adsorption efficacy is improved, but interference with essential nutrients occurs

Engineering Contradiction:
Improveadsorption efficacyVSAvoidinterference with essential nutrients
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent applies local quality by creating a targeted adsorption system where the adsorbent material has specific chemical properties that allow it to bind DON selectively. The adsorbent is designed with particular surface characteristics and chemical groups that interact strongly with DON molecules while having minimal affinity for essential nutrients, thus achieving localized effective adsorption without widespread interference.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs parameter changes by modifying the chemical and physical parameters of the adsorbent material. This includes adjusting the surface area, pore size distribution, chemical composition, and surface charge characteristics of the adsorbent to optimize its binding affinity for DON while maintaining neutrality toward essential nutrients. These parameter optimizations enable selective adsorption behavior.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional adsorbents are used to adsorb DON, then adsorption efficacy is improved, but toxicity at therapeutic doses occurs

Engineering Contradiction:
Improveadsorption efficacyVSAvoidtoxicity at therapeutic doses
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies this principle by using an adsorbent material that is non-toxic and can be safely excreted or degraded in the animal body after performing its function. The adsorbent is designed to be biocompatible and environmentally benign, eliminating the concern of accumulation toxicity while maintaining effective DON adsorption capabilities throughout the therapeutic period.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent modifies the safety parameters of the adsorbent by selecting materials with inherently low toxicity and optimizing their pharmacokinetic properties. The adsorbent is designed to have appropriate half-life, biodegradability, and metabolic pathways that prevent toxic accumulation, thereby achieving effective therapy without harmful side effects.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If phyllosilicates are used as adsorbents, then cost-effectiveness is improved, but adsorption efficacy for DON is insufficient

Engineering Contradiction:
Improvecost-effectivenessVSAvoidadsorption efficacy for DON
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent applies composite materials by combining phyllosilicate minerals with other adsorbent components or modifying the phyllosilicate structure to enhance its DON binding capabilities. This composite approach retains the cost-effectiveness of phyllosilicates while adding functional groups or structural features that significantly improve DON adsorption efficacy, achieving both economic and performance goals.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the parameters of phyllosilicate-based adsorbents by adjusting mineral composition, particle size, surface area, and chemical modification levels. These parameter changes enhance the adsorption capacity for DON while maintaining the cost-effectiveness advantage of using phyllosilicate materials, balancing performance and economy.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compound achieves high adsorption efficacy for DON and other mycotoxins, maintaining stability throughout the digestive system without sequestering essential vitamins and minerals, offering a non-toxic and cost-effective solution for mycotoxicosis prevention and treatment.

Implementation Method 1

adsorbents: This technique consists of the use of substances which act as mycotoxin anchors, preventing them from being adsorbed by the animal

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP3430913B1Composition for binding mycotoxins and its use
Publication Date: 2020.12.02 TOLSA
  • EP3430913B1 patent drawingFigure 1~2
  • EP3430913B1 patent drawingFigure 3~4
  • EP3430913B1 patent drawingFigure 5~6

AI summary

The present invention relates to a compound with mycotoxin-adsorbent properties, characterised in that it comprises: (a) at least one magnesium phyllosilicate in a percentage comprised between 25% and 75% by weight of the total mixture; (b) at least one aluminium phyllosilicate in a percentage comprised between 25% and 85% by weight of the total mixture; and (c) activated vegetable charcoal in a percentage comprised between 1% and 10% by weight of the total mixture. Another object of the invention is the obtainment method and use thereof as a raw material in the formulation of compound feed, as an additive in finished mixtures intended for direct consumption by the animal or as an ingredient in the formulation of complex mycotoxin-adsorbent additives.