Transdermal Patch Regulator with Roller Actuator for Adaptive Dosing
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Solution Overview
Problem
Current transdermal drug delivery systems lack precise control over timing, rate, and dosage, often leading to suboptimal drug administration due to fixed schedules and lack of adaptability to individual biological rhythms and responses.
Innovation Solution
A regulator system for transdermal drug administration that includes a connector, actuator, and controller to manipulate the drug patch's engagement and disengagement with the skin, allowing for customizable dosage schedules, adjustable rates, and responsive administration based on pre-programmed or sensed events.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If a fixed schedule transdermal drug patch is used, then the device complexity is low, but the adaptability to individual biological rhythms and responses is poor
Solution Approach 1:
The patent implements dynamic control of drug delivery by allowing the patch to be engaged and disengaged at different times, transforming a static fixed-schedule system into a dynamic adaptable system that responds to individual biological rhythms and patient needs
Solution Approach 2:
The patent enables parameter changes by allowing modification of delivery timing and dosage through controlled engagement and disengagement of the patch, transforming a fixed-parameter system into one with adjustable parameters that can be tailored to individual patient requirements
2Measurement precision
If a fixed schedule transdermal drug patch is used, then the ease of operation is high, but the precision of drug delivery control is poor
Solution Approach 1:
The patent segments the continuous drug delivery process into controllable engagement and disengagement phases, allowing precise control over when drug delivery occurs while maintaining simple operation through clear binary states of patch attachment and detachment
3Reliability
If automated and adaptive dosing is implemented, then the therapeutic efficacy is improved, but the device complexity increases
Solution Approach 1:
The patent implements feedback mechanisms by monitoring patient responses and biological rhythms, then using this information to adjust future engagement and disengagement schedules, creating a closed-loop system that improves therapeutic efficacy through adaptive learning
Data Source
AI summary
Embodiments are disclosed of a method of controlling timing and/or dosage of a transdermal drug patch. For example, a control device operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being fully engaged with the skin, partially engaged with the skin, and disengaged with the skin. The device may include a roller that peels a patch on and off the skin. Optionally a convention patch is used. In some embodiments a patch and/or an adaptor has a mobile zone and an immobile zone. In some embodiments, an active surface of the patch fully contacts the skin in an engaged state. For example the patch may be attached to the device on a passive portion thereof.