Portable Food Allergen Sensor Chip Using MIP Resistance Detection

The patent extracts the core detection function from complex laboratory equipment and implements it using a simplified sensor chip with molecularly imprinted polymers. The MIPs are synthesized to specifically bind allergen molecules, enabling accurate detection without the need for sophisticated analytical instruments. This extraction of the essential detection mechanism allows the system to maintain high accuracy while dramatically reducing device complexity and size for point-of-consumption use.

The patent changes the detection parameter from complex spectroscopic or chromatographic measurements to simple electrical resistance measurements. By functionalizing the sensor chip with MIPs and measuring resistance changes when allergens bind to the polymer receptors, the system achieves accurate allergen detection using basic electrical measurement circuits instead of sophisticated analytical equipment, thereby reducing device complexity while maintaining detection accuracy.

The patent performs preliminary action by pre-synthesizing molecularly imprinted polymers with specific binding sites for target allergens before the detection event. These MIPs are prepared in advance with optimized binding characteristics, allowing rapid binding kinetics when exposed to food samples. The pre-formed receptor sites enable fast association with allergen molecules, achieving rapid detection response without compromising the sensitivity required for trace molecule detection.

The patent uses composite materials by combining molecularly imprinted polymers with conductive materials on the sensor chip. The MIP layer provides specific binding capability for sensitive detection, while the conductive composite enables rapid electrical measurement. This composite structure allows simultaneous achievement of high detection sensitivity for trace allergens and rapid response time for practical point-of-consumption use.