Boron-Free Potassium Carbonate Immunostimulant Composition

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Solution Overview

Problem

Current nonspecific immunostimulant compositions are limited in their application due to the presence of boron, which is suspected to be unsafe for the body, and they lack broad applicability to animals, plants, and humans, as well as effective resistance against diseases such as avian influenza and foot-and-mouth disease.

Innovation Solution

A potassium carbonate-based multifunctional complex mineral composition comprising sodium silicate, sodium thiosulfate, sodium carbonate, potassium chloride, white sugar, and optionally magnesium sulfate and silver thiosulfate, which is free from boron and enhances immunostimulation and disease resistance in animals and humans.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If borax is used in the composition to achieve immunostimulatory effects, then the immunostimulatory effect on animals and plants is improved, but the safety of the composition is worsened due to unknown effects of boron on the body

Engineering Contradiction:
Improveimmunostimulatory effectVSAvoidsafety
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent removes borax (the harmful component) from the composition while retaining other beneficial ingredients like potassium carbonate, sodium silicate, and white sugar. This extraction of the harmful substance allows the composition to maintain its immunostimulatory effects without the safety concerns associated with boron

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the chemical composition parameters by replacing borax with alternative substances. The new composition uses potassium carbonate as the primary ingredient instead of borax, fundamentally altering the chemical profile while achieving the desired immunostimulatory effects without harmful boron content

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If a complex composition containing multiple ingredients is used to achieve broad immunostimulatory effects, then the versatility and effectiveness are improved, but the preparation complexity and storage convenience are worsened

Engineering Contradiction:
Improvebroad applicabilityVSAvoidpreparation complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent creates a universal composition that can be applied to multiple targets including animals, plants, and humans. The simplified formula with core ingredients like potassium carbonate, sodium silicate, and white sugar provides broad immunostimulatory coverage across different species without requiring separate complex formulations for each application

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent uses a composite material approach by combining naturally occurring substances (potassium carbonate, sodium silicate, white sugar, water) that work synergistically together. This composite formulation achieves complex immunostimulatory effects through the interaction of simpler, naturally compatible components rather than requiring highly complex synthetic materials

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS9687545B2Nonspecific immunostimulator composition, method of preparation the same, and its use
Publication Date: 2017.06.27 BARODON S F CORP
  • US9687545B2 patent drawing
  • US9687545B2 patent drawing
  • US9687545B2 patent drawing

AI summary

Disclosed are a nonspecific immunostimulant composition, a preparation method thereof, and uses thereof. The composition includes 150 to 300 wt. parts of sodium silicate, 2˜8 wt. parts of sodium thiosulfate, 0.5˜2 wt. parts of sodium carbonate, 0.5˜2 wt. parts of potassium chloride, 200˜400 wt. parts of white sugar, and 300˜400 wt. parts of water, based on 100 wt. parts of potassium carbonate. The composition exhibits excellent defense against the mortality caused by AIV H5N1, thus improving the survival of infected animals. As a supplement of a formulated feed mixture for farmed aquatic organisms, the composition provides excellent immunostimulation and disease resistance so as to decrease the mass mortality of aquatic organisms and to increase productivity. Particularly, when raised with a food in mixture with the composition, livestock and farmed aquatic organisms are immunologically improved so that they can endure and are protected against epidemic diseases caused by viruses and bacteria.