Antibacterial Agents TRIZ Cases

Endolysins degrade peptidoglycan to eliminate antibiotic-tolerant persister bacteria.

Segmenting rifampin and isoniazid into separate tablet layers prevents chemical degradation while maintaining fixed-dose combination therapy.

Solid cellulose polymer absorbs API solution to form ocular delivery devices without high temperatures.

A bacteriophage composition targets and lyses specific pathogenic bacteria in ballast water without generating toxic chemical byproducts.

A site-specific intestinal delivery system releases adsorbents to capture residual antibiotics in the lower gut.

A topical composition combining copper sulphate with hypericum perforatum extract to deliver synergistic antiviral action at the outbreak site.

Bacillus subtilis DE111 secretes surfactin and iturin to resolve inadequate pathogen control by disrupting microbial adhesion.

A Coa binding antibody targets Domain 1 of the Staphylococcal Coa polypeptide to neutralize bacterial virulence factors.

Modified endolysin variants fuse cationic peptides to degrade bacterial peptidoglycan layers.

PsP190 and PsP290 recombinant proteins act as vaccine antigens to overcome intracellular Piscirickettsia salmonis resistance and reduce mortality.

Acetic acid wound dressing removes biofilm infections using negative pressure therapy to overcome antibiotic resistance.

Selective extraction removes pro-inflammatory saponins from quinoa grains, enabling dermatological use without triggering inflammatory responses.

Sorbitan monocaprylate supports antimicrobial agents to reduce preservative concentrations, minimizing toxicity risks while maintaining formulation stability.

Optimized metabolizable oil and tocopherol concentrations in an oil-in-water emulsion reduce reactogenicity while maintaining immunogenicity.

Water-soluble polymers modify calcium silicate particle interactions to eliminate sand-like texture while maintaining a tight bacterial seal.

Modified beta-lactamase substrate retains color change response after polymer conjugation.

Automated microwell plate system generates a phagogram to identify susceptible phages without manual operations or pure culture isolates.

Inhibiting MafB and c-Maf overcomes the trade-off between macrophage differentiation and cell expansion.

A Sargassum horneri water extract with a molecular weight of 3,000 or less inhibits transcription activation by NF-kB in osteoblasts and osteoclast precursor cells.

Myceliophthora thermophila spores destroy pathogenic gram-positive bacteria, resolving antibiotic resistance and toxicity issues in hygiene applications.

Beneficial bacterial strains suppress Staphylococcus aureus populations by competing for skin resources, avoiding antibiotic resistance side effects.

Brilliant Blue G complexes with bacteriostatic agents to reduce cytotoxic effects on healing cells while retaining bacterial protection.

Ulva algae extract with low molecular weight polysaccharides treats resistant bacteria without complex synthesis.

CNCM I-3689 strain maintains viability in dairy products while delivering consistent antimicrobial effects.

An extended acting oxygen generating system boosts the lactoperoxidase reaction to produce bactericidal agents.

Replacing borax with potassium carbonate removes safety risks while maintaining disease resistance against avian influenza.

Alkyl-heterocycle carbamate derivatives inhibit fatty acid amide hydrolase while minimizing cytochrome P450 CYP3A4 interaction.