Proanthocyanidin Bee Feed Composition for Pollen-Free Nutrition

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Commercially available bee feeds do not contain biologically significant concentrations of proanthocyanidins, which are known to be toxic to insects but have health-promoting effects in humans, and existing extraction methods fail to provide nutritionally effective amounts for bees, leading to limitations in bee colony health, reproduction, and survival.

Innovation Solution

A pollen-free diet enriched with proanthocyanidins in polymeric or oligomeric forms, administered at nutritionally effective amounts, is provided to honey bees through a composition comprising proteins, fatty acids, carbohydrates, vitamins, and minerals, sourced from non-pollen plant or synthetic origins, in both solid and liquid forms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If proanthocyanidins are extracted using water-based methods, then the extraction process is simple and safe, but proanthocyanidins are not present in nutritionally effective amounts because they are water-insoluble

Engineering Contradiction:
Improveextraction process simplicityVSAvoidproanthocyanidin concentration
Core Design Contradiction:
Ease of manufactureVSQuantity of substance

Solution Approach 1:

The patent changes the extraction parameter from water-based to ethanol-based solvent system. Ethanol effectively extracts proanthocyanidins while maintaining safety for bee consumption, achieving both high concentration extraction and ease of manufacture

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses food-grade ethanol as a disposable extraction solvent that can be easily removed through evaporation, leaving concentrated proanthocyanidin extract suitable for bee feed without requiring complex purification steps

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Productivity

If proanthocyanidins are added to bee feed, then bee brood production and worker survival improve, but the feed composition becomes more complex

Engineering Contradiction:
Improvebee brood productionVSAvoidfeed composition complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent extracts proanthocyanidins as a separate concentrated component from plant materials, then incorporates this extract into bee feed at controlled levels (0.1-5% of total diet), simplifying the overall feed formulation while maintaining health benefits

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a composite bee feed composition combining proanthocyanidin extract with other essential nutrients (proteins, carbohydrates, lipids, vitamins, minerals) in specific ratios, achieving balanced nutrition enhanced with proanthocyanidins without excessive complexity

Inventive Principle:
Principle #40Composite materials

3Reliability

If proanthocyanidins are sourced from natural plant tissues, then the feed is natural and safe for bees, but the concentration of proanthocyanidins is insufficient for nutritional effectiveness

Engineering Contradiction:
Improvesafety for beesVSAvoidproanthocyanidin concentration
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent performs preliminary extraction of proanthocyanidins from plant materials before feeding to bees, concentrating the active compounds in advance. This ensures bees receive nutritionally effective doses without exposing them to other potentially harmful plant constituents

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses ethanol as an intermediary extraction medium that selectively binds proanthocyanidins from plant tissue. The ethanol-proanthocyanidin complex is then processed into a safe, concentrated feed supplement that delivers effective doses to bees

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP4408187B1Proanthocyanidins (condensed tannins) as nutrient for honey bees
Publication Date: 2026.03.04 APIX BIOSCIENCES
  • EP4408187B1 patent drawingFigure 1~2
  • EP4408187B1 patent drawingFigure 3
  • EP4408187B1 patent drawing

AI summary

Provided are methods for feeding invertebrates comprising:  providing a non-pollen composition comprising a nutritionally effective amount of proanthocyanidins; and  administering the non-pollen composition to invertebrates.