Probiotic Composition for Viral Infection Immune Response

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Solution Overview

Problem

There is a need for effective methods to boost the immune system to prevent and treat viral infections, particularly in the context of COVID-19, as existing solutions are inadequate in addressing the immune system's response to viral infections effectively.

Innovation Solution

Administering a probiotic composition containing high CFU counts of specific strains of probiotic bacteria such as Streptococcus, Lactobacillus, and Lactococcus, which are formulated to provide anti-viral effects and enhance immune response, either as a treatment or prevention method for viral infections like COVID-19.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If probiotic composition is administered to boost immune system and prevent viral infection, then immune system response is improved, but there is no established mechanism or evidence for effectiveness

Engineering Contradiction:
Improveimmune system responseVSAvoidmechanism of action
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The patent introduces probiotic bacteria as intermediary substances that mediate between the host immune system and viral pathogens. The probiotics serve as a biological mediator that modulates immune responses and provides antiviral effects through specific bacterial strains interacting with the host's immune machinery.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces conventional antiviral medications with probiotic-based biological mechanisms. Instead of using chemical antivirals, the invention employs probiotic bacteria and their metabolic products (such as short-chain fatty acids, bacteriocins, and immunomodulatory molecules) to achieve antiviral effects.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If high CFU counts of probiotic bacteria are used, then anti-viral effect is enhanced, but manufacturing complexity increases

Engineering Contradiction:
Improveanti-viral effectVSAvoidmanufacturing process
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple probiotic bacterial strains into a single composite formulation. By merging different strains (such as Lactobacillus, Bifidobacterium, and other beneficial bacteria) into one probiotic composition, the invention achieves enhanced antiviral effects while simplifying the manufacturing process compared to producing and coordinating multiple separate bacterial products.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent optimizes specific parameters of the probiotic formulation, including CFU counts, strain ratios, and delivery formats. By carefully controlling these parameters during manufacturing, the invention achieves high antiviral efficacy while maintaining manufacturing feasibility through standardized production protocols.

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If probiotic composition is administered as treatment or prevention, then viral infection severity is reduced, but lack of standardized protocols limits effectiveness

Engineering Contradiction:
Improveviral infection severityVSAvoidstandardization protocol
Core Design Contradiction:
Object-affected harmful factorsVSEase of manufacture

Solution Approach 1:

The patent develops a probiotic composition that serves multiple functions: prevention of viral infection, treatment of existing infection, modulation of immune response, and support of gut health. This multi-functionality allows the same probiotic formulation to be applied across different scenarios without requiring separate standardized protocols for each indication.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent emphasizes preliminary administration of probiotics before viral infection occurs to establish protective immune responses and gut microbiota balance. By taking probiotics in advance, the body is prepared to better respond to potential viral challenges, reducing the need for complex treatment protocols after infection occurs.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The probiotic composition effectively boosts the immune system, providing anti-viral effects and reducing the severity or incidence of viral infections, as demonstrated by case studies showing reduced infection rates and rapid recovery in subjects administered with the probiotic formulation.

Implementation Method 1

the probiotic bacteria within the probiotic composition are capable of producing CFUs in the trillions

Methodology Applied
Scientific EffectCellular division:

Data Source

PatentUS20230158089A1Probiotic compositions and methods of use
Publication Date: 2023.05.25 CHANDLER BIOPHARMACEUTICAL CORP

AI summary

Probiotic compositions capable of generating a high CFU count and methods to improve the health of a subject including to treat or prevent a viral infection are disclosed.