Propolis Zedoary Mint Vaginal Agent

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Solution Overview

Problem

Current gynecological vaginal medicaments often irritate vaginal mucosa cells, leading to secondary pollution, reduced secretion function, and increased risk of infections due to high impurity content and inadequate antibacterial and anti-inflammatory effects, failing to effectively prevent repeated infections and maintain vaginal health.

Innovation Solution

A natural Chinese herbal external-use agent comprising propolis extract, zedoary oil, and mint leaf filtrate, processed using CO2 extraction and ethanol, is developed to provide antibacterial, anti-inflammatory, and deodorizing effects without irritating vaginal mucosa cells, promoting immune function and self-healing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical medicaments with anti-inflammatory and antibacterial effects are used, then therapeutic efficacy is improved, but irritation to vaginal mucosa cells increases

Engineering Contradiction:
Improvetherapeutic efficacyVSAvoidirritation to vaginal mucosa
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by replacing synthetic chemicals with natural Chinese herbal extracts (propolis extract, zedoary oil, mint leaf filtrate), maintaining antibacterial and anti-inflammatory effects while reducing mucosal irritation through different chemical properties of natural compounds

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses a composite formulation combining multiple Chinese herbal extracts (propolis, zedoary, mint) that work synergistically to provide both therapeutic efficacy and reduced irritation, leveraging the complementary properties of different natural materials

Inventive Principle:
Principle #40Composite materials

2Manufacturing precision

If lotions and emulsions are used to clean the vagina, then cleaning effect is improved, but secretion function of vaginal mucosa cells decreases due to flushing out secretions

Engineering Contradiction:
Improvecleaning effectVSAvoidsecretion function of vaginal mucosa
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The patent promotes self-service by enhancing the vagina's natural self-cleaning ability through stimulating secretory function of mucosa cells, rather than relying on external cleaning agents that remove protective secretions. The formulation supports the body's own cleaning mechanisms

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the approach from mechanical/chemical cleaning to biological regulation by using herbal extracts that modulate secretory function, transforming the parameter from external cleaning force to internal secretory activity

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If medicaments with high impurity content are used, then manufacturing cost is reduced, but damage to secretory function of vaginal mucosa cells increases

Engineering Contradiction:
Improvemanufacturing costVSAvoiddamage to secretory function
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent applies extraction technology to obtain pure active components from Chinese herbal materials (propolis extract, zedoary oil, mint leaf filtrate), removing impurities while concentrating therapeutic ingredients, thus achieving both high purity and cost-effectiveness through efficient extraction processes

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The agent effectively prevents repeated infections, maintains vaginal health, reduces itching, and enhances the secretion function of vaginal cells, with a 100% effective rate in clinical trials, providing a non-toxic and safe solution for gynecological care.

Implementation Method 1

processed using CO2 extraction and ethanol

Methodology Applied
Scientific EffectCO2 extraction: Supercritical Fluid Extraction

Implementation Method 2

dissolving the propolis extract, zedoary extract (zedoary oil) and mint leaf filtrate of the above-mentioned amounts, in accordance with requirement of the formula composition, into ethanol solution

Methodology Applied
Scientific EffectDissolution: Solvation

Data Source

PatentUS10478463B2External-use medicament for cleaning and care of the ovaries, vagina, and vulva
Publication Date: 2019.11.19 SHAANXI LIANGDI BIOTECH CO LTD

AI summary

An external-use agent for cleaning and caring ovaries, vagina and vulva, which is produced by medical raw materials consisting of propolis extract, zedoary oil, and mint leaf filtrate is provided. On the basis of different properties of each natural Chinese herbal material, using supercritical CO2 technology, separation and extraction, and low-temperature centrifugation are carried out respectively, and they are processed for preparation in a proportion, and then the membrane separation is performed, so that a spraying agent or a caring product is manufactured. It may be used alone in a female reproductive system for preventing the repeated infection and for achieving vulval bacteriostatic or antibacterial purposes and cleaning and deodorizing the vagina, eliminating vulval pruritus, and refreshing and moisturizing vulva and vagina etc., with good cleaning and caring functions and achieving a significant effect.