PRP Blood Analysis With Automated Yield and Concentration Metrics
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Solution Overview
Problem
Current blood analyzers do not automatically determine the performance quality of platelet rich plasma (PRP) by comparing it against the complete blood count (CBC) of the derived sample, requiring tedious and time-consuming manual calculations.
Innovation Solution
A system integrated into a hematology analyzer that automatically compares PRP counts with CBC to calculate and display percentage yields, concentrations, and deliverable quantities of platelets and other constituents, providing immediate qualitative assessment of PRP quality and effectiveness.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If manual calculations are performed to determine PRP quality metrics, then accuracy of yield and concentration determination can be achieved, but time consumption and operational complexity increase significantly
Solution Approach 1:
The blood analyzer performs self-service by automatically calculating PRP quality metrics (yield, concentration, deliverable quantities) without requiring external manual intervention. The device compares PRP counts against CBC data and autonomously generates performance quality indicators, eliminating the need for physicians to perform tedious manual calculations while maintaining high accuracy.
Solution Approach 2:
The patent replaces the mechanical calculation process (manual computations by physicians) with an automated electronic system. The blood analyzer uses its built-in processor to automatically compare PRP counts with CBC data and calculate quality metrics, substituting human manual operations with machine-based computational processes that are both faster and equally accurate.
2Measurement precision
If manual calculations are performed to determine PRP quality metrics, then comprehensive quality assessment can be achieved, but operational complexity and time requirements increase
Solution Approach 1:
The blood analyzer autonomously performs the complete quality assessment process by automatically comparing PRP counts against CBC data and generating comprehensive quality metrics including yield, concentration, and deliverable quantities. This self-service capability maintains comprehensive assessment completeness while eliminating operational complexity for the user.
Solution Approach 2:
The blood analyzer extends its functionality to perform multiple tasks: it not only counts blood cells but also compares PRP counts with CBC data and calculates various quality metrics (yield, concentration, deliverable quantities). This multi-functionality consolidates what would otherwise require separate manual calculation processes into a single automated system, maintaining comprehensive assessment while improving ease of operation.
3Productivity
If automated comparison of PRP counts against CBC is implemented, then productivity and speed of quality determination improve, but device complexity increases
Solution Approach 1:
The blood analyzer leverages its existing multi-functional capability to perform both CBC analysis and PRP quality assessment. By utilizing the same device for multiple purposes (cell counting and quality metric calculation), the system achieves high productivity without proportionally increasing device complexity, as the additional functionality builds upon the existing analytical framework.
Solution Approach 2:
The automated comparison and calculation process is performed autonomously by the blood analyzer using its existing computational resources. The device uses its built-in processor to automatically compare PRP counts with CBC data and generate quality metrics, leveraging its existing self-service capabilities to achieve high speed determination without requiring additional complex external systems.
Data Source
AI summary
A PRP analyzing system is constructed and programmed to determine a baseline complete blood count of a whole blood sample and a blood count of PRP derived from the sample. The system compares the baseline and PRP blood counts and calculates qualitative PRP metrics such as constituent percentage yield, concentration and deliverable of PRP constituents. This provides immediate, understandable and compelling indication of the likely performance and effectiveness of the PRP in medical applications.