Collaborative High-Voltage Pulse Ablation and Electrophysiological Recording System
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Solution Overview
Problem
Current electrophysiological recording systems during high-voltage pulse field ablation procedures face challenges such as measurement location deviation, interference of high-voltage electric pulse signals, and potential damage to the recording system, which hinder accurate real-time observation and storage of cardiac electrical signals.
Innovation Solution
An apparatus with collaborative operation between high-voltage pulse field ablation and electrophysiological recording systems, comprising a high-voltage power supply, energy storage capacitor, discharge circuit, high-frequency high-voltage pulse signal generation circuit, switch array circuit, and control system, allowing for real-time collection, display, and storage of cardiac electrical signals without interference from high-voltage pulses.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a mapping catheter is used to collect cardiac electrical potential signals during high-voltage pulse field ablation, then real-time observation of ablation efficacy is enabled, but the measurement location is offset from the actual tissue site and high-voltage pulse signals interfere with the recording system
Solution Approach 1:
The invention divides the catheter system into functionally separate components: an ablation catheter for delivering high-voltage pulses and a separate mapping catheter for recording electrophysiological signals. This segmentation allows each catheter to be optimized for its specific function, with the mapping catheter positioned to accurately measure signals at the actual tissue site while the ablation catheter delivers pulses without interfering with measurements
Solution Approach 2:
The invention introduces an intermediary coupling device that connects the mapping catheter to the electrophysiological recording system. This intermediary component isolates the sensitive recording system from high-voltage pulse interference while maintaining signal transmission, solving the contradiction between enabling real-time observation and preventing signal interference
2Reliability
If high-voltage electric pulses are delivered during ablation, then non-thermal ablation with cell selectivity is achieved, but the pulse signals interfere with electrophysiological recording and may damage the recording system
Solution Approach 1:
The invention introduces an intermediary coupling device that connects the mapping catheter to the electrophysiological recording system. This intermediary component isolates the sensitive recording system from high-voltage pulse interference while maintaining signal transmission, solving the contradiction between enabling real-time observation and preventing signal interference
Solution Approach 2:
The invention extracts the electrophysiological recording function from the ablation system by using a separate mapping catheter connected through an intermediary device. This separation removes the recording system from the high-voltage pulse environment, eliminating the harmful interference and damage risks while preserving the selectivity benefits of pulse field ablation
3Device complexity
If a single catheter is used for both ablation and signal recording, then device complexity is reduced, but the measurement location deviates from the actual tissue site and signal interference occurs
Solution Approach 1:
The invention divides the catheter system into functionally separate components: an ablation catheter for delivering high-voltage pulses and a separate mapping catheter for recording electrophysiological signals. This segmentation allows each catheter to be optimized for its specific function, with the mapping catheter positioned to accurately measure signals at the actual tissue site while the ablation catheter delivers pulses without interfering with measurements
Solution Approach 2:
The invention creates a universal catheter system where both ablation and mapping functions can be performed simultaneously through separate catheters. The system maintains versatility by allowing independent optimization of each function while working together in a unified ablation and monitoring platform
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate and real-time observation, collection, and storage of cardiac electrical signals during ablation procedures, preventing signal interference and system damage, thereby providing correct and reliable measurements.
Implementation Method 1
an energy storage capacitor connected respectively to a high-voltage power supply, a discharge circuit and a high-frequency high-voltage pulse signal generation circuit
Implementation Method 2
a discharge circuit connected to the energy storage capacitor
Implementation Method 3
PEF energy can create irreversible micropores in the membrane of a cell through instantaneous discharge, eventually causing apoptosis of the cell and achieving non-thermal ablation, also known as irreversible electroporation
Implementation Method 4
using an electrophysiological recording system to display electrophysiological signals collected by a mapping catheter from the heart
Data Source
AI summary
An apparatus with collaborative operation between high-voltage pulse field ablation and an electrophysiological recording system pertains to the field of medical devices and includes a high-voltage power supply, an energy storage capacitor, a discharge circuit, a high-frequency high-voltage pulse signal generation circuit, a switch array circuit and a control system. The energy storage capacitor is connected respectively to the high-voltage power supply, the discharge circuit and the high-frequency high-voltage pulse signal generation circuit. The switch array is connected respectively to the high-frequency high-voltage pulse signal generation circuit, a catheter and the electrophysiological recording system. The control system is connected respectively to the high-voltage power supply, the discharge circuit, the high-frequency high-voltage pulse signal generation circuit, the switch array circuit, a cardiac electrical signal monitor and a foot pedal switch.