Pulsed Electrical Stimulation for Microbial Metabolism Control

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Solution Overview

Problem

Current bio-electrochemical synthesis methods lack efficiency in converting electrical energy into chemical energy using microbes, as they rely on continuous direct current stimulation, which does not effectively stimulate resonant molecules or control microbial electron uptake and release.

Innovation Solution

The use of pulsed or modulated electrical current, specifically alternating current, is applied between electrodes in a bioreactor containing electro-autotrophic microbes and carbon dioxide, allowing for efficient conversion of electrical energy into chemical energy stored in organic compounds, with optional mediation and control through sensors to optimize production and microbial growth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If continuous direct current stimulation is applied to microbes in a bioreactor, then the system operates continuously, but the conversion efficiency of electrical energy to chemical energy is low because resonant molecules are not effectively stimulated

Engineering Contradiction:
Improveconversion efficiency of electrical energy to chemical energyVSAvoidenergy loss in continuous DC stimulation
Core Design Contradiction:
ProductivityVSLoss of energy

Solution Approach 1:

The patent applies pulsed electrical stimulation instead of continuous direct current to resonate with molecular oscillations in microbes. By using periodic action at specific frequencies, the system effectively stimulates resonant molecules to facilitate electron transport chains, thereby improving energy conversion efficiency while reducing energy loss.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent utilizes electrical vibration at resonant frequencies to stimulate molecular oscillations within microbes. This mechanical vibration approach enhances the effectiveness of energy transfer to resonant molecules, improving the overall conversion efficiency of electrical energy to chemical energy in the bioreactor system.

Inventive Principle:
Principle #18Mechanical vibration

2Productivity

If pulsed or modulated electrical current is applied to stimulate resonant molecules, then energy conversion efficiency improves, but the system complexity increases due to need for frequency modulation and control

Engineering Contradiction:
Improveenergy conversion efficiencyVSAvoidcomplexity of pulsed current control system
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs frequency modulation of electrical current as a controllable parameter to resonate with molecular oscillations. By changing the frequency parameter of the applied electrical signal, the system achieves enhanced energy conversion efficiency while maintaining manageable system complexity through parameter optimization rather than structural complexity.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If specific frequencies are used to stimulate resonant molecules, then microbial metabolism is enhanced and target molecule production increases, but the measurement and control requirements become more stringent

Engineering Contradiction:
Improvetarget molecule productionVSAvoidprecision required for frequency control
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent implements feedback control mechanisms to monitor and adjust the frequency of electrical stimulation in real-time. This feedback system ensures that the applied frequencies remain optimized for resonant molecular stimulation, thereby enhancing target molecule production while managing the precision requirements through active control rather than passive fixed-frequency operation.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enhances the production of organic compounds by stimulating microbial metabolism, favoring specific species and metabolic pathways, and allows for efficient conversion of renewable energy into chemical energy, such as dense fuels like octadecane, while capturing carbon and releasing oxygen as a by-product.

Implementation Method 1

Living organisms transfer electrons through their electron transport chains as the core of their most basic metabolism

Methodology Applied
Scientific EffectElectron transport chain:

Implementation Method 2

Microbes that fix carbon from CO2 and obtain energy from electricity are known herein as electro-autotrophs

Methodology Applied
Scientific EffectElectro-autotrophy:

Implementation Method 3

By pulsing and modulating the electrical input, it is possible to more efficiently stimulate the resonant molecules of the microbes

Methodology Applied
Scientific EffectResonance: Resonance

Implementation Method 4

Chemoautotrophs obtain energy from the oxidation of inorganic compounds and obtain carbon from the fixation of carbon dioxide

Methodology Applied
Scientific EffectCarbon fixation:

Implementation Method 5

capturing carbon and releasing oxygen as a by-product

Methodology Applied
Scientific EffectOxygen evolution:

Data Source

PatentUS9096847B1Methods for control, measurement and enhancement of target molecule production in bioelectric reactors
Publication Date: 2015.08.04 ARCOLOGY INC DBA BIOSPHERE
  • US9096847B1 patent drawing
  • US9096847B1 patent drawing
  • US9096847B1 patent drawing

AI summary

Bioreactors comprising an electrical stimulation system supply a pulsed and/or modulated electrical input to microbes that use the electrical stimulation and available CO2 to produce valuable organic compounds. Electrical power, such as from renewable sources remotely located with respect to the power grid, can be converted to chemical energy in the form of the organic compounds, which can be stored and/or transported readily.