Shaped Bone Fiber Products via Demineralization
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Solution Overview
Problem
Existing methods for manufacturing shaped bone fiber-based products face challenges in achieving adequate physical properties such as mold release, flexibility, compressibility, and cohesiveness, with prior art methods often requiring excipients and specialized drying conditions.
Innovation Solution
A method involving the selection of specific fiber shapes and sizes, hydration with a water-miscible low boiling solvent, molding, and controlled drying/lyophilization to enhance self-adhesion, flexibility, and compressibility, using bone or other materials like wood and thermoplastics, with a focus on maintaining properties like shape, cohesiveness, and pliability post-rehydration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If excipients and specialized drying conditions (pressure, lyophilization) are used to manufacture shaped bone fiber-based products, then the desired shape and physical properties are achieved, but the manufacturing complexity and cost increase
Solution Approach 1:
The patent changes the physical-chemical parameters of the bone fiber material itself through controlled demineralization to achieve desired shape and physical properties without requiring complex specialized drying equipment. The demineralization process modifies the material's inherent properties to enable self-supporting shaped structures.
Solution Approach 2:
The patent extracts and removes the need for excipients and specialized drying conditions by using demineralized bone fiber material that inherently maintains shape and physical properties through its modified structural characteristics, eliminating dependency on additional carriers or complex processing equipment.
2Stability of the object's composition
If demineralized bone particles are used with carriers like glycerol to achieve cohesiveness, then the composition maintains cohesiveness, but the product requires additional excipients and becomes less pure
Solution Approach 1:
The patent modifies the bone fiber material parameters through controlled demineralization to achieve the desired cohesiveness and physical properties inherently, eliminating the need for additional carrier substances like glycerol and maintaining bone fiber purity.
3Ease of manufacture
If oven-drying is used to form sheets from bone particles, then the sheets can be cut to size, but the process requires high temperature and energy consumption
Solution Approach 1:
The patent changes the material properties of bone fibers through demineralization to enable sheet formation and size cutting at lower temperatures with reduced energy consumption, while maintaining the desired manufacturability.
4Manufacturing precision
If lyophilization is used to finish drying before warming, then the shaped material can be formed in desired shape, but the process time and equipment complexity increase
Solution Approach 1:
The patent modifies the bone fiber material parameters through demineralization to achieve desired shape accuracy with reduced drying time and simplified equipment requirements, eliminating the need for multi-step lyophilization processes.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method produces bone fiber-based products with improved self-adhesion, flexibility, and compressibility, retaining over 90% integrity after rehydration and maintaining desired properties for at least a year, with a controlled void-to-fiber ratio and rapid rehydration capabilities.
Implementation Method 1
hydration with a water-miscible low boiling solvent
Implementation Method 2
controlled drying/lyophilization
Implementation Method 3
controlled drying/lyophilization
Data Source
AI summary
The present invention relates to shaped, bone fiber-based products and methods to make the same.