Sterol Esterase Enzyme Sebum Removal Detergent

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Solution Overview

Problem

Current laundry detergents fail to effectively remove sebum stains from fabrics, particularly due to the difficulty in degrading the components of sebum, which consists of fats, esters, and waxes, especially at lower washing temperatures.

Innovation Solution

Incorporation of a novel sterol esterase enzyme with high sequence identity into detergent compositions, combined with surfactants, soil release polymers, and additional enzymes, to enhance the breakdown and removal of sebum from fabrics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current commercial enzymes are used in detergent compositions, then the detergent can be formulated with standard ingredients, but the sebum removal from fabrics is inadequate

Engineering Contradiction:
Improvesebum removal effectivenessVSAvoidcleaning performance
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies parameter changes by introducing a novel sterol esterase enzyme with specific sequence identity parameters (at least 60%, preferably at least 70%, more preferably at least 75%, more preferably at least 80%, more preferably at least 85% identity to SEQ ID NO: 1 or 2) to improve sebum removal effectiveness while maintaining standard detergent formulation parameters

Inventive Principle:
Principle #35Parameter changes

2Use of energy by moving object

If washing temperature is reduced to encourage energy efficiency, then energy consumption decreases, but the ability to degrade sebum components becomes insufficient

Engineering Contradiction:
Improveenergy consumptionVSAvoidsebum degradation capability
Core Design Contradiction:
Use of energy by moving objectVSReliability

Solution Approach 1:

The patent resolves this contradiction by changing the enzymatic parameter - using a novel sterol esterase enzyme that maintains high sebum degradation capability at lower washing temperatures, thereby reducing energy consumption without sacrificing cleaning reliability

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The novel sterol esterase enzyme significantly improves sebum removal from fabrics, demonstrated by increased stain removal index (SRI) compared to existing commercial enzymes, indicating better cleaning performance even at lower washing temperatures.

Implementation Method 1

incorporation of a novel sterol esterase enzyme in detergent compositions improve the sebum removal from fabrics

Methodology Applied
Scientific EffectEnzyme catalysis: Enzyme

Implementation Method 2

the novel sterol esterase enzyme significantly improves sebum removal from fabrics, demonstrated by increased stain removal index

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Implementation Method 3

liquid detergent composition comprising: (i) from 1 to 60 wt.%, preferably from 2 to 50 wt.%, more preferably from 3 to 45 wt.%, even more preferably from 5 to 40 wt.%, most preferably from 6 to 40 wt.% of a surfactant

Methodology Applied
Scientific EffectSurfactant action: Surfactant

Data Source

PatentEP3884024B1Detergent composition
Publication Date: 2024.08.07 UNILEVER GLOBAL IP LTD
  • EP3884024B1 patent drawing
  • EP3884024B1 patent drawing
  • EP3884024B1 patent drawing

AI summary

The invention provides a detergent composition comprising: (i) from 1 to 60 wt.% of a surfactant; and, (ii) from 0.0005 to 5 wt.% of a sterol esterase enzyme; to a method using the enzyme and to the use of the enzyme to improve cleaning of sebum stains on fabric; wherein the sterol esterase enzyme has at least 60%, preferably at least 70%, more preferably at least 75%, more preferably at least 80%, more preferably at least 85%, even more preferably at least 90%, even more preferably at least 95%, most preferably at least 97%, at least 98% or even at least 99%, most preferably 100% sequence identity to any one of SEQ ID NO: 1 or 2.10.