Traditional Chinese Medicine Composition for Tumor Treatment

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current treatments for malignant tumors, such as surgery, chemotherapy, and radiotherapy, face challenges with postoperative recovery and harmful side effects, highlighting the need for an anti-tumor drug with significant efficacy and minimal side effects.

Innovation Solution

A traditional Chinese medicine composition is developed using a specific blend of herbs like Sophora flavescens, wild chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root, and Radix glycyrrhizae, processed through ethanol percolation and decoction to create a compound powder, offering a potential anti-tumor treatment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgery, chemotherapy or radiotherapy is used to treat malignant tumors, then tumor removal or control is achieved, but postoperative recovery is difficult or harmful side effects occur

Engineering Contradiction:
Improveanti-tumor efficacyVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses a composite traditional Chinese medicine formulation containing multiple herbal components (sophora flavescens, wild chrysanthemum flower, honeysuckle, mint, poria cocos, atractylodes lancea, cinnamon, clove, astragalus, ganoderma lucidum, ligusticum striatum, aucklandia root, and radix glycyrrhizae) to achieve anti-tumor effects while reducing side effects through synergistic interactions among the herbs

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the weight percentage ratios of different herbal ingredients in the formulation, with specific ranges provided for each component (e.g., sophora flavescens 3%-12%, wild chrysanthemum flower 5%-15%), to achieve the optimal balance between anti-tumor efficacy and side effect reduction

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional anti-tumor drugs are developed to treat increasing tumor patients, then treatment effectiveness is improved, but toxic side effects increase

Engineering Contradiction:
Improveanti-tumor effectVSAvoidtoxic side effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent converts the potentially harmful concentrated dosing requirement into a benefit by using multiple herbal components that work synergistically at lower individual doses, reducing overall toxicity while maintaining or improving anti-tumor effectiveness

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent changes the dosing parameters by providing specific weight percentage ranges for each herbal ingredient, allowing for optimized dosing that achieves therapeutic effects with minimal toxic side effects

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition demonstrates significant anti-tumor efficacy by enhancing immune function and reducing tumor volume in pharmacodynamic tests, with the added benefit of being easily obtainable and cost-effective.

Implementation Method 1

processed through ethanol percolation and decoction to create a compound powder

Methodology Applied
Scientific EffectSolvent extraction: Liquid-Liquid Extraction

Implementation Method 2

processed through ethanol percolation and decoction to create a compound powder

Methodology Applied
Scientific EffectHeating: Heating

Data Source

PatentEP3597207B1Traditional chinese medicine composition for treating tumours, preparation method therefor and use thereof
Publication Date: 2022.04.20 ZUO ANGANG

AI summary

Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.