Antineoplastic Agents TRIZ Cases
- Antitumoral Composition Using Zebrafish miRNAs for Cell Reprogramming
Zebrafish microRNA composition reprograms cancer cells to a normal phenotype, addressing the limitation of conventional treatments that damage healthy tissue.
- Synergistic SCD1 and Tyrosine Kinase Inhibitor Combinations for HCC
Combining selective SCD1 inhibitors with tyrosine kinase inhibitors targets hepatocellular carcinoma through dual-mechanism action.
- HIF-2α PAS-B Domain Cavity Targeting for Selective Inhibition
Targeting the HIF-2α PAS-B cavity disrupts dimerization with HIF1β, resolving specificity issues against HIF1α.
- Memetic Optimization Algorithm for Radiation Therapy Planning
A memetic optimization algorithm determines beam geometry and dosimetric parameters to generate radiation therapy treatment plans.
- Amcenestrant and Ribociclib Combination for Breast Cancer
Merging amcenestrant and ribociclib overcomes limited anti-tumor efficacy of single agents by inducing significant tumor stasis.