Phase Contrast X-ray Elastic Modulus Calculation

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Solution Overview

Problem

Existing elastography techniques using MRI and ultrasonic waves for determining the elastic modulus of viscoelastic bodies suffer from low spatial resolution, making it difficult to detect small lesions or distinguish between lesion and normal regions accurately.

Innovation Solution

A method utilizing a phase contrast X-ray optical system without fringe scanning to calculate the elastic modulus by maintaining the relative positional relationship between diffraction gratings and using X-ray projection images to detect refraction and scattering, enabling high spatial resolution and reduced measurement time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If fringe scanning using phase contrast X-ray optical system is used to improve spatial resolution and sensitivity, then measurement time increases and X-ray exposure amount increases

Engineering Contradiction:
Improvespatial resolutionVSAvoidmeasurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent extracts and removes the fringe scanning step from the phase contrast X-ray imaging process. By using a phase contrast X-ray optical system without fringe scanning, the method directly acquires phase information from the projection images, eliminating the time-consuming grating movement required for traditional fringe scanning while maintaining high spatial resolution

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces the mechanical fringe scanning system with a computational approach. Instead of physically moving gratings to create interference fringes, the system uses phase contrast X-ray optics combined with image processing algorithms to extract phase information directly from the projection images, substituting mechanical movement with optical and computational methods

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If multiple imaging is performed to improve measurement accuracy, then X-ray exposure amount increases and subject movement likelihood increases

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidX-ray exposure amount
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent implements continuous vibration of the viscoelastic body throughout the imaging process. By applying continuous vibration and continuously acquiring projection images during the vibration, the system obtains sufficient data for accurate elastic modulus calculation in a single imaging session, eliminating the need for repeated imaging while maintaining measurement precision

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent uses periodic vibration of the viscoelastic body at a specific frequency. By exciting the object with periodic vibration and acquiring projection images during this periodic motion, the system can extract elastic modulus information from the vibration response without requiring multiple separate imaging acquisitions, thereby reducing total X-ray exposure

Inventive Principle:
Principle #19Periodic action

3Productivity

If Fourier transform method is used to calculate phase image without fringe scanning, then measurement time is reduced but spatial resolution decreases

Engineering Contradiction:
Improvemeasurement speedVSAvoidspatial resolution
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent changes the optical parameters of the X-ray system by using phase contrast X-ray optics with specific grating configurations. This parameter change in the optical system allows direct acquisition of phase information with high spatial resolution without requiring fringe scanning, achieving both fast measurement and high resolution simultaneously

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces phase contrast X-ray optics as an intermediary between the X-ray source and the detector. This intermediary optical system directly encodes phase information into the projection images through phase contrast effects, eliminating the need for subsequent Fourier transform processing or fringe scanning while preserving high spatial resolution

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method achieves high spatial resolution in calculating the elastic modulus of viscoelastic bodies, allowing for accurate detection of small lesions and clear boundary differentiation between lesion and normal regions with reduced imaging time.

Implementation Method 1

a phase contrast X-ray optical system capable of detecting refraction or scattering of X-rays by an object

Methodology Applied
Scientific EffectDiffraction: Diffraction

Implementation Method 2

the grating portion including a first diffraction grating and a second diffraction grating disposed in parallel with a self-image of the first diffraction grating

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 3

a vibration unit that vibrates the object

Methodology Applied
Scientific EffectMechanical vibration: Vibration

Implementation Method 4

calculating an elastic modulus of the object based on a displacement amount of a wave due to the vibration

Methodology Applied
Scientific EffectShear wave propagation: Waveguide

Implementation Method 5

a phase contrast X-ray optical system capable of detecting refraction or scattering of X-rays by an object

Methodology Applied
Scientific EffectRefraction: Refraction

Implementation Method 6

a phase contrast X-ray optical system capable of detecting refraction or scattering of X-rays by an object

Methodology Applied
Scientific EffectScattering: Scattering

Data Source

PatentUS20250110066A1Method for calculating elastic modulus and device for calculating elastic modulus
Publication Date: 2025.04.03 TOHOKU UNIV
  • US20250110066A1 patent drawing
  • US20250110066A1 patent drawing
  • US20250110066A1 patent drawing

AI summary

An elastic modulus of a viscoelastic body can be calculated with a high spatial resolution and in a relatively short measurement time. A projection image of an X-ray is detected with a detection unit by vibrating an object while maintaining a relative positional relationship between a first diffraction grating and a second diffraction grating. Then, an elastic modulus of the object is calculated based on a displacement amount of a wave due to the vibration in the projection image of the X-ray detected by the detection unit.