A nonlinear fusion method of internal and external radiotherapy doses for cervical cancer

A non-linear fusion technology for cervical cancer, applied in radiation therapy, equipment for radiation diagnosis, X-ray/γ-ray/particle irradiation therapy, etc. Break through technical limitations and improve the effect of radiation therapy

CN106902477BActive Publication Date: 2019-08-09福建省肿瘤医院 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2019-08-09

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Abstract

The invention relates to a non-linear fusion method for internal and external radiotherapy doses of a cervical cancer. The method comprises: obtaining internal and external irradiation radiotherapy CT images and internal and external irradiation radiotherapy dose distribution of a to-be-detected cervical cancer; on the basis of non-linear image registration, mapping the internal irradiation radiotherapy CT image to the external irradiation radiotherapy CT image to obtain a transformation relationship between the internal and external irradiation radiotherapy CT images of the to-be-detected cervical cancer; according to the transformation relationship between the internal and external irradiation radiotherapy CT images, transforming internal irradiation radiotherapy dose distribution into equivalent external irradiation radiotherapy dose distribution; and carrying out fusion of the equivalent external irradiation radiotherapy dose distribution and external irradiation radiotherapy dose distribution after transformation by image fusion, rebuilding a distribution curve of internal and external radiotherapy doses, and obtaining a total practically subjected dose of a tumor target region of the to-be-detected cervical cancer and surrounding organs at risks during the comprehensive internal and external irradiation radiotherapy process. The non-linear fusion method is applied to an image-guided radiation therapy of a cervical cancer, thereby improving accuracy of radiotherapy dose evaluation.
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Description

technical field

[0001] The invention relates to the technical field of medical image processing and image-guided radiotherapy, in particular to a nonlinear fusion method of internal and external radiotherapy doses for cervical cancer. Background technique

[0002] Cervical cancer is the second most common tumor in women worldwide, which seriously threatens women's life and health. Although the current health conditions have been greatly improved, the morbidity and mortality are still increasing in developing countries and some areas. Studies have found that the incidence of cervical cancer has even tended to be younger in recent years. Radiation therapy is one of the most important means of cervical cancer treatment, and more than 70% of cervical cancer patients worldwide include radiation therapy. The basic goal of radiotherapy is to try to increase the gain ratio of radiotherapy, that is, in the process of radiotherapy for cervical cancer, the irradiation dose given to th...

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Embodiment Construction

[0041] The technical solution of the present invention will be specifically described below in conjunction with the accompanying drawings.

[0042] The invention provides a nonlinear fusion method of internal and external radiotherapy doses for cervical cancer, which is characterized in that it is implemented according to the following steps:

[0043] Step S1: Acquiring CT images of internal radiation therapy, CT images of external radiation therapy, dose distribution of internal radiation therapy and dose distribution of external radiation therapy of cervical cancer to be detected;

[0044] Step S2: Correspondingly mapping the CT images of internal radiation therapy to CT images of external radiation therapy through nonlinear image registration, so that the images of internal and external radiation therapy can achieve consistent anatomical structure, and eliminate the errors caused by patient setup errors, treatment responses and physiological activities, etc. The deviation o...