Traditional Chinese medicine composition for treating constipation and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating constipation and a preparation method thereof, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20g of radix aconiti lateralis preparata, 5-15g of fructus evodiae, 20-30g of herba epimedii, 35-45g of radix astragali, 10-20g of ginseng, 5-15g of rhizoma atractylodis macrocephalae, 20-35g of semen coicis, 50-60g of fructus aurantii immaturus, 10-20g of betel nut and 5-15g of honey-fried licorice root. Comprising the following steps: (1) accurately weighing the raw materials in parts by weight, respectively pulverizing, sieving with a 200-mesh sieve, and mixing to obtain mixed medicinal powder for later use; and 2) adding the mixed medicine powder into a full-automatic traditional Chinese medicine watered pill machine, adding cooked millet accounting for 1-5% of the total amount of the mixed medicine powder, starting the full-automatic traditional Chinese medicine watered pill machine, and processing to obtain watered pills.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and in particular to a traditional Chinese medicine composition for treating constipation and a preparation method thereof. Background Art

[0002] Constipation, as a common digestive system disease, has long troubled many patients, and its incidence rate is high worldwide. Since the treatment of constipation was recorded in Zhang Zhongjing's Treatise on Febrile Diseases, Chinese medicine has been mainly treating constipation by purging fire and relieving constipation for more than 2,000 years. This treatment has a sense of urgency before defecation and has poor long-term efficacy. It is the root cause of intractable constipation, that is, the reason why constipation cannot be cured.

[0003] Western medicine usually relies on laxatives or enemas to treat constipation. Although these methods may be effective in the short term, long-term use may lead to side effects such as drug dependence and intestinal dysfunction.

[0004] According to TCM theory, the root cause of constipation is the weakness of human yang qi, dampness and qi stagnation, and the inability to excrete waste. Weak yang qi leads to weakened intestinal peristalsis, and the internal accumulation of dampness makes the intestinal environment sticky, the qi is not smooth, and the powerlessness of pushing feces excretion makes it difficult to excrete waste (feces). Most patients with constipation have the characteristics of yang qi deficiency, and patients have symptoms of chills, cold limbs, cold abdomen, and pale tongue. The main clinical manifestations of the disease are prolonged intervals between bowel movements and difficulty in defecation. It mainly refers to a decrease in the number of bowel movements, a decrease in the amount of feces, dry or hard feces, or laborious defecation when the feces are not dry. When more than two of the above symptoms exist at the same time, symptomatic constipation can be diagnosed. Usually, the main feature is a decrease in the frequency of bowel movements, generally once every 2 to 3 days or longer, or less than 3 times a week, which is constipation. Since the Treatise on Febrile Diseases, TCM has mainly used heat-clearing and purgation as the treatment for constipation.

[0005] Existing Chinese herbal preparations for treating constipation often have less than ideal effects, and the treatment time is long or even many years without recovery, causing great pain and mental burden to patients.

[0006] In view of the shortcomings of existing treatments, the present invention proposes a Chinese medicine composition with warming yang and invigorating qi, strengthening the spleen and eliminating dampness, and promoting qi and removing stagnation as the main treatment principles. The prescription provided by the present invention mainly treats spleen and stomach digestive dysfunction with pure Chinese medicine, and the treatment is mainly based on warming yang and invigorating qi, strengthening the spleen and eliminating dampness, and promoting qi and removing stagnation, without using heat-clearing and purgative drugs, so that the intestines can produce natural defecation ability, with good long-term efficacy, stable efficacy, and not easy to relapse. Summary of the invention

[0007] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a Chinese medicine composition for treating constipation and a preparation method thereof.

[0008] To solve the above technical problems, the technical solution provided by the present invention is a traditional Chinese medicine composition for treating constipation, which comprises the following raw materials in parts by weight: 10-20 grams of aconite root, 5-15 grams of evodia rutaecarpa, 20-30 grams of epimedium, 35-45 grams of astragalus, 10-20 grams of ginseng, 5-15 grams of atractylodes macrocephala, 20-35 grams of coix seed, 50-60 grams of immature bitter orange, 10-20 grams of areca catechu, and 5-15 grams of roasted licorice.

[0009] Furthermore, the Chinese medicine composition includes the following raw materials in parts by weight: 15 grams of aconite root, 10 grams of evodia rutaecarpa, 30 grams of epimedium, 40 grams of astragalus, 15 grams of ginseng, 10 grams of atractylodes macrocephala, 30 grams of coix seed, 60 grams of immature bitter orange, 15 grams of areca catechu, and 10 grams of roasted licorice.

[0010] Furthermore, the preparation method of the Chinese medicine composition comprises the following steps:

[0011] Step 1) First, accurately weigh the raw materials according to the above weight parts, grind them into powder respectively, pass them through a 200-mesh sieve, and mix them to obtain a mixed powder for later use;

[0012] Step 2) adding the mixed powder into a fully automatic Chinese medicine water pill machine, and simultaneously adding 1%-5% of the total amount of the mixed powder into cooked millet, starting the fully automatic Chinese medicine water pill machine, and processing to obtain water pills.

[0013] The advantages of the present invention compared with the prior art are:

[0014] 1) The Chinese medicine composition provided by the present invention is composed of aconite root, evodia rutaecarpa, epimedium, astragalus, ginseng, atractylodes, coix seed, immature bitter orange, betel nut, and licorice. Aconite root can restore yang and rescue adverse conditions, replenish fire and promote yang, and dispel cold and relieve pain; evodia rutaecarpa can dispel cold and relieve pain, reduce adverse conditions and stop vomiting, and promote yang and stop diarrhea; epimedium can travel through the liver and kidney meridians to replenish life gate, benefit essence and qi, strengthen tendons and bones, and strengthen kidney and yang; astragalus can strengthen spleen and replenish middle, raise yang and lift sunken, benefit wei and consolidate the exterior, promote diuresis, and promote toxin and promote muscle regeneration; ginseng can greatly replenish vital energy, restore pulse and consolidate collapse , tonifying the spleen and lungs, promoting fluid and nourishing blood, calming the mind and improving intelligence; Atractylodes macrocephala: tonifying the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus; Coix seeds: promoting diuresis and penetrating dampness, tonifying the spleen and stopping diarrhea, removing numbness, discharging pus, detoxifying and dispersing knots; Citrus aurantium: breaking up qi and eliminating accumulation, resolving phlegm and removing lumps; Areca nut: killing insects and eliminating accumulation, promoting qi, promoting diuresis, and stopping malaria; Roasted licorice: nourishing yin and blood, replenishing qi and promoting yang, restoring pulse and calming palpitations; the prepared medicine can quickly regulate the movement of human qi and regulate gastrointestinal balance, and is suitable for oral administration by people over 10 years old with constipation;

[0015] 2) The Chinese medicine composition provided by the present invention has completely changed the method of purging fire and relieving constipation that was popular in the past in traditional Chinese medicine. In terms of the selection of Chinese medicine varieties, it has changed the medication standard of purging fire and relieving constipation to warming, invigorating and promoting qi, thus overcoming the defects of the prior art. DETAILED DESCRIPTION

[0016] The following is a further detailed description of a Chinese medicine composition for treating constipation and a preparation method thereof according to the present invention in conjunction with embodiments.

[0017] Example 1

[0018] A Chinese medicine composition for treating constipation, comprising the following raw materials in parts by weight: 15 grams of aconite root, 10 grams of evodia rutaecarpa, 30 grams of epimedium, 40 grams of astragalus, 15 grams of ginseng, 10 grams of atractylodes macrocephala, 30 grams of coix seed, 60 grams of immature bitter orange, 15 grams of areca nut, and 10 grams of roasted liquorice;

[0019] The preparation method of the Chinese medicine composition comprises the following steps:

[0020] Step 1) First, accurately weigh the raw materials according to the above weight parts, grind them into powder respectively, pass them through a 200-mesh sieve, and mix them to obtain a mixed powder for later use;

[0021] Step 2) adding the mixed powder into a fully automatic Chinese medicine water pill machine, and simultaneously adding 3% of the total amount of the mixed powder into cooked millet, starting the fully automatic Chinese medicine water pill machine, and processing to obtain water pills.

[0022] Example 2

[0023] The decoction obtained in Example 1 was used to treat patients with constipation, and the treatment results were statistically analyzed according to the diagnostic criteria and efficacy criteria.

[0024] The dosage of the decoction: in clinical application, the decoction obtained in Example 1 is taken orally, one dose per day, twice a day, morning and evening, on an empty stomach. Six days is one course of treatment. During the treatment period, avoid eating raw, cold, spicy and stimulating foods.

[0025] The diagnostic criteria are: Refer to the diagnostic criteria for constipation in the "Standards for Diagnosis and Efficacy of TCM Diseases and Syndromes" issued by the State Administration of Traditional Chinese Medicine:

[0026] 1. Defecation time is prolonged, more than once every two days, and the stool is dry and hard;

[0027] 2. In severe cases, the stool is difficult and dry like chestnuts, and may be accompanied by abdominal distension, fatigue, and decreased appetite;

[0028] 3. Eliminate organic intestinal diseases.

[0029] Efficacy standards: Refer to the efficacy standards for constipation in the "Diagnosis and Efficacy Standards of Traditional Chinese Medicine Diseases and Syndromes" issued by the State Administration of Traditional Chinese Medicine:

[0030] 1) Recovery: defecation once within 2 days, smooth stool, no recurrence in the short term;

[0031] 2) Effective: defecation within 3 days, smooth stool, and smooth defecation;

[0032] 3) Ineffective: No improvement in symptoms.

[0033] In the clinical observation cases, a total of 50 patients were counted, of which 50 patients took medication for 2-5 courses, and 50 patients were cured, and no recurrence was observed during follow-up.

[0034] Example 3

[0035] 1) Wang Taotao, 58 years old, female, retired employee, first diagnosed on January 16, 2023. The patient has been constipated since she was 25 years old, for 33 years, with a bowel movement once every 4 days, and once every 2 days at best. Every bowel movement is very painful, and taking detoxification and beauty capsules, compound aloe capsules, Chinese medicine decoctions, various enzymes, etc., can not completely improve.

[0036] Diagnosis: defecation once every 3-4 days, need to take laxatives to defecate, feces are not dry, weak to defecate, feel not completely resolved after defecation, want to defecate again. Accompanied by fear of cold, cold limbs, cold abdomen, fatigue, dry mouth and stickiness, pale tongue, fat, with tooth marks, deep and thin pulse. Dialectical belongs to weak yang qi, dampness and qi stagnation, and dregs cannot be discharged. Immediately take the decoction obtained in Example 1, defecate once after two days, and defecate once a day when the treatment is continued for two weeks.

[0037] After that, the water pills prepared in Example 2 were taken orally, twice a day, 6-9 grams each time, and the Chinese medicine was stopped after two and a half months of consolidation treatment. So far, the patient has bowel movements once a day at 6 am, the stools are moderately hard and soft, and there is no discomfort before and after bowel movements. The original symptoms such as fear of cold, fatigue and weakness have been significantly improved.

[0038] 2) Patient: Zhang Mourong, gender: female, age: 55 years old, occupational farmer, admitted to the hospital on 2024.09.11 14:57 due to "left limbs have been inactive for more than 7 years". The patient started to suffer from constipation 15 years ago, and has been undergoing intermittent rehabilitation treatment for 7 years due to right limb paralysis caused by cerebrovascular disease.

[0039] Current diagnosis: right limb paralysis, difficulty walking and standing, fatigue, cold sweat, bowel movement once every 5 days, soft stool, no urge to defecate, feeling of incomplete defecation after defecation, dry, sticky, bad breath, fear of cold, cold limbs, cold abdomen, pale and fat tongue, greasy white tongue coating, deep and thin pulse. Dialectical diagnosis is weak Yang Qi, dampness and Qi stagnation, and dregs cannot be discharged.

[0040] The patient was given an agent for warming and tonifying Yang Qi, promoting blood circulation and unblocking meridians, strengthening the spleen and removing dampness, and promoting the circulation of Qi and removing stagnation. Five doses of the decoction obtained in Example 1 were taken orally, and one dose was taken orally every day. During the 5-day follow-up visit, the patient had bowel movements once every 3 days, and the feeling of uncleanness after bowel movements was alleviated, fatigue and weakness, cold sweats were improved, and dry mouth and stickiness disappeared. After taking the medicine for two weeks, the patient had bowel movements once a day, and the feeling of uncleanness after bowel movements was alleviated, fatigue and weakness were improved, cold sweats were slight, and the coldness of the abdomen was improved, but the patient was still afraid of cold. The patient was urged to continue taking Chinese medicine for 1-2 months to consolidate the treatment.

[0041] 3) Hu Moupin, male, 52 years old, freelancer. First visit: October 6, 2023. The patient had irregular bowel movements due to hemiplegia caused by cerebral infarction 5 years ago. He began to seek medical attention 3 years ago because of defecation once every 3-4 days and painful defecation. He has been taking "Compound Aloe Vera Capsules" for more than a year. After taking the medicine, the defecation pain is relieved, but he must take the medicine every day to ensure that he has a bowel movement once a day. If he does not take it, he will not have a bowel movement.

[0042] Examine: patient's complexion is pale, dizziness is weak, defecation is 1 time in 4-5 days, feces is not dry, sometimes is loose stool, very afraid of cold, epigastric cold, cold sweat is much, lethargy, pale tongue has tooth mark, white greasy tongue coating, deep and fine pulse. Dialectical belongs to deficiency of yang qi, dampness and qi stagnation, give Chinese medicine to warm yang and replenish qi, invigorate spleen and eliminate dampness, promote qi circulation and remove stagnation treatment, oral embodiment 1 obtained decoction 7 doses, 1 dose orally every day, and stop taking compound aloe capsule. After 7 days, follow-up visit: dizziness, fatigue, lethargy are alleviated, stool is 1 time every 2 days, feces is improved than before, and cold sweat is reduced. Original prescription continues to serve stool 1 time every day during two weeks of follow-up visit, feces is moderately hard and soft, dizziness and fatigue are improved, and there is no obvious lethargy.

[0043] The patient continued to take the above-mentioned prescription drugs for two months. He had a bowel movement once a day in the morning, with moderate hardness and softness. He had no discomfort before and after bowel movements. He never felt dizzy or weak again. He occasionally had a small amount of cold sweat, and his fear of cold was significantly reduced. The patient was asked to stop taking the drugs for observation for half a year. He felt more energetic than before, his digestive function was significantly improved, he had a bowel movement once a day, with moderate hardness and softness, and his fear of cold was reduced.

[0044] The present invention and its implementation methods are described above, and such description is not restrictive. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design structures and embodiments similar to the technical solution without creativity, which should all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine composition for treating constipation, characterized in that: The Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 grams of aconite root, 5-15 grams of evodia rutaecarpa, 20-30 grams of epimedium, 35-45 grams of astragalus, 10-20 grams of ginseng, 5-15 grams of atractylodes macrocephala, 20-35 grams of coix seed, 50-60 grams of immature bitter orange, 10-20 grams of areca nut, and 5-15 grams of roasted liquorice.

2. The Chinese medicine composition according to claim 1, characterized in that: The Chinese medicine composition comprises the following raw materials in parts by weight: 15 grams of aconite root, 10 grams of evodia rutaecarpa, 30 grams of epimedium, 40 grams of astragalus, 15 grams of ginseng, 10 grams of atractylodes macrocephala, 30 grams of coix seed, 60 grams of immature bitter orange, 15 grams of areca catechu, and 10 grams of roasted liquorice.

3. The method for preparing the Chinese medicine composition according to any one of claims 1 to 2, characterized in that: The following steps are involved: Step 1) First, accurately weigh the raw materials according to the above weight parts, grind them into powder respectively, pass them through a 200-mesh sieve, and mix them to obtain a mixed powder for later use; Step 2) adding the mixed powder into a fully automatic Chinese medicine water pill machine, and simultaneously adding 1%-5% of the total amount of the mixed powder into cooked millet, starting the fully automatic Chinese medicine water pill machine, and processing to obtain water pills.