A traditional Chinese medicine preparation for dispelling wind and dampness and application thereof

This traditional Chinese medicine preparation, made by rationally combining seven Chinese herbs including honeysuckle vine, solves the problem of the insignificant efficacy of existing Chinese patent medicines in treating gout. It achieves significant anti-inflammatory, analgesic, and uric acid-lowering effects, alleviating the symptoms and adverse reactions of gout patients.

CN119587629BActive Publication Date: 2025-12-09HENAN MEDICAL DEVICE INSPECTION INST
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Patent Information

Application Number
CN202411768587.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-04
Publication Date
2025-12-09
Estimated Expiration
2044-12-04

AI Technical Summary

Technical Problem

Existing traditional Chinese medicine treatments for acute gout attacks are not very effective and have adverse reactions, affecting patients' quality of life. Modern drug treatments may cause gastrointestinal adverse reactions and kidney damage.

Method used

This invention provides a traditional Chinese medicine preparation composed of honeysuckle vine, chicken blood vine, silkworm excrement, gentian root, safflower, peach kernel, fraxinus bark, arisaema cum bile, medicated leaven, and bee honeycomb. Through reasonable formulation, it is prepared into oral dosage forms such as pills, powders, and decoctions for the purpose of dispelling wind and dampness, clearing heat and detoxifying, promoting blood circulation and removing blood stasis, regulating the spleen and stomach, and comprehensively treating gout.

Benefits of technology

It significantly reduced joint swelling in rats with acute gouty arthritis, decreased the expression of serum TNF-α, IL-1β, and IL-6 inflammatory factors, reduced serum uric acid and creatinine, alleviated pain, improved quality of life, and reduced the incidence of adverse reactions.

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Abstract

The application provides a traditional Chinese medicine preparation for dispelling wind and removing dampness and application, and relates to the technical field of traditional Chinese medicine preparation, wherein the traditional Chinese medicine preparation is composed of ten traditional Chinese medicines including Lonicera japonica, Spatholobus suberectus Dunn, silkworm sand, gentiana, safflower, persica, cortex fraxini, ardisia japonica, medicated leaven and honeycomb; the traditional Chinese medicine preparation can significantly reduce the swelling degree of ankle joint of an acute gouty arthritis model rat, reduce the expression level of serum TNF-alpha, IL-1beta and IL-6 inflammatory factors, and reduce the content of serum uric acid, creatinine and XOD, so as to achieve the effects of anti-inflammation and analgesia, reduction of blood uric acid, and the like; the clinical test results show that the traditional Chinese medicine preparation can reduce the pain degree of a patient, reduce the levels of inflammation related factors TNF-alpha and IL-1beta in synovial fluid of a knee joint of the patient, reduce the inflammation indexes WBC, ESR and CRP in serum, reduce the inflammation reaction of the patient's body, reduce the incidence of adverse reactions, and provide a new traditional Chinese medicine preparation with high safety and good curative effect for the treatment of acute attack of gout.
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