Boletus brownii xylan palmitate as well as preparation method and application thereof

By preparing and optimizing xylan palmitate from Boletus chapensis, its structural characteristics and intestinal flora regulation mechanism were clarified, thus solving the bottleneck in polysaccharide development, achieving high bioactivity and wide application, and promoting its industrialization in functional foods and biomedicine.

CN120795202AActive Publication Date: 2025-10-17YANTAI UNIV
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Patent Information

Application Number
CN202511292397.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-11
Publication Date
2025-10-17
Estimated Expiration
2045-09-11

AI Technical Summary

Technical Problem

The structural properties and biological functions of *Boletus circinus* polysaccharide in the prior art are unclear, the utilization rate of alcohol-soluble low molecular weight components is low, and its mechanism of action in immunomodulation and anti-tumor related products is vague, which restricts its industrial application.

Method used

A xylan palmitate (SLEP) from *Boletus globosum* was prepared. Its structural characteristics were clarified by optimizing the extraction process, and its immune-enhancing mechanism through intestinal microbiota regulation was revealed, providing a highly bioactive polysaccharide conjugate.

Benefits of technology

The xylan palmitate of *Boletus chapensis*, which provides a clear structural feature and high bioactivity, has solved the bottleneck in polysaccharide development, achieved efficient utilization of alcohol-soluble components and immune-enhancing effects through intestinal flora regulation, and promoted its application in functional foods and biomedicine.

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Abstract

The invention discloses boletus brownii xylan palmitate as well as a preparation method and application thereof. The boletus brownii xylan palmitate is xylan palmitate which is formed by alpha-(1-> 4)-xylose as a main chain, alpha-(1->)-glucose as a branch chain and palmitic acid molecules through ester bonds. The invention further discloses a preparation method of the boletus brownii xylan palmitate and application of the boletus brownii xylan palmitate in the aspect of immunoregulation. The boletus brownii xylan palmitate can be used as a dietary supplement or a food additive for immunodeficiency patients and tumor patients.
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