Imidazolyl and dinitrophenyl derivative and application thereof
By developing compound (I) and its derivatives, the safety issues of existing mitochondrial decoupling agents have been resolved, achieving safe and effective reduction of fat storage and treatment of obesity.
CN121013841APending Publication Date: 2025-11-25BEIJING SHUANGHE RUNCHUANG TECH CO LTD
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Patent Information
- Application Number
- CN202480021353.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-06-07
- Filing Date
- 2024-05-10
- Publication Date
- 2025-11-25
AI Technical Summary
Technical Problem
Existing mitochondrial decoupling agents have safety and potential side effects issues in treating obesity, and there is a need to develop safe and effective mitochondrial decoupling agents to reduce fat content and treat related diseases.
Method used
Compounds of formula (I) and their derivatives, stereoisomers and pharmaceutically acceptable salts have been developed to reduce fat storage by modulating mitochondrial activity, including imidazole and dinitrophenyl derivatives, for the treatment of obesity and related diseases.
Benefits of technology
It provides a safe and effective mitochondrial decoupling agent that can regulate mitochondrial activity, reduce fat content, and has the potential therapeutic effect on obesity and related diseases.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention relates to compounds of formula (I), stereoisomers thereof, deuterated derivatives thereof, pharmaceutically acceptable salts thereof, pharmaceutically acceptable salts of stereoisomers thereof or pharmaceutically acceptable salts of deuterated derivatives thereof, as well as pharmaceutical compositions containing these compounds and uses thereof.
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