Cartilage graft and construction method thereof
By regenerating cartilage membranes or cartilage microtissues in vitro, combined with high-density seeding and special induction culture, cartilage grafts were prepared, solving the problems of insufficient chondrocyte numbers, dedifferentiation, and difficulty in shaping. This achieved stable, controllable large-volume cartilage regeneration and repair effects with low complications.
Patent Information
- Application Number
- CN202610123972.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2017-01-23
- Publication Date
- 2026-04-14
AI Technical Summary
Existing technologies for repairing cartilage defects suffer from problems such as insufficient chondrocyte numbers, dedifferentiation, difficulty in shaping, and uncontrollable regeneration effects, which limit their clinical application.
By regenerating cartilage membranes or cartilage microtissues in vitro, and utilizing high-density seeding and a special chondrogenic induction culture system, combined with injectable media, cartilage grafts can be prepared to achieve large-volume cartilage regeneration and controllable shaping.
It provides cartilage grafts with stable, controllable, and easily shaped cartilage regeneration effects and a low incidence of postoperative complications, overcoming the shortcomings of traditional techniques and achieving safe and controllable regeneration of large-volume cartilage.