Peptides having skin whitening activity and uses thereof
By developing novel peptides that inhibit the uptake of melanosomes by keratinocytes, the problem of the lack of multi-mechanism synergistic effects in existing skin whitening agents has been solved, achieving effective skin whitening and prevention or treatment of hyperpigmentation.
CN122094967APending Publication Date: 2026-05-26CAREGEN
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Patent Information
- Application Number
- CN202480065662.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2023-10-16
- Filing Date
- 2024-10-14
- Publication Date
- 2026-05-26
AI Technical Summary
Technical Problem
Existing skin whitening agents mainly focus on inhibiting tyrosinase activity, lacking the ability to achieve synergistic skin whitening effects through different mechanisms and sites of action.
Method used
A novel peptide has been developed that inhibits the uptake of melanosomes by keratinocytes and achieves skin whitening by inhibiting the expression of PAR2, TLR3 and KGFR genes. It can be applied to skin whitening compositions, pharmaceutical compositions and cosmetic compositions.
Benefits of technology
It effectively inhibits the absorption of melanosomes, prevents or treats hyperpigmentation, and achieves skin whitening.
✦ Generated by Eureka AI based on patent content.
Abstract
The peptides of the present invention exhibit skin whitening activity by inhibiting melanin body uptake in keratinocytes. Therefore, the peptide of the present invention can be used as an active ingredient in a medicament for treating or preventing hyperpigmentation diseases caused by excessive deposition of melanin bodies, or as an active ingredient in a cosmetic for skin whitening.
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