A compound oral liquid of Saussurea involucrata and a preparation method thereof

By combining seven Chinese herbal medicines and applying natural antibacterial agents, the problems of sweeteners and chemical preservatives in Chinese herbal oral liquids have been solved, resulting in the preparation of Snow Lotus Oral Liquid with good palatability, high stability, and strong safety, achieving multi-target conditioning and green production.

CN122398946APending Publication Date: 2026-07-17NANJING XIYUAN BIOPHARML SCI & TECH
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Patent Information

Application Number
CN202610704814.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-21
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing oral liquids of traditional Chinese medicine have problems with the addition of extra sweeteners and chemical preservatives, and the formulation is not scientifically sound. It is difficult to balance the stability and safety of the preparation, and it cannot meet the needs of green, safe and convenient preparations.

Method used

It employs a precise combination of seven traditional Chinese medicines, along with the natural compound antibacterial agents ε-polylysine hydrochloride and nisin. The extract is obtained through a low-temperature negative pressure ultrasonic cavitation water extraction process and prepared under specific temperature control, eliminating the need for traditional sweeteners and chemical preservatives, thus achieving a synergistic antibacterial effect.

Benefits of technology

The prepared snow lotus oral liquid has a pleasant taste, strong stability, and high safety, making it suitable for people who control their blood sugar and those who prefer natural preparations. It has a multi-target conditioning effect of warming the kidneys and tonifying yang, replenishing qi and nourishing yin, and strengthening the spleen and removing dampness. Moreover, the process is simple and suitable for large-scale production.

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Abstract

本发明提供了一种雪莲口服液及其制备方法,属于中药制剂技术领域。本发明采用马鹿茸、雪莲培养物、甘草、西洋参、红景天、茯苓、黄精按特定比例复配而成,添加ε‑聚赖氨酸盐酸盐与乳酸链球菌素,全程不添加甜味剂及山梨酸钾等传统化学防腐剂,依托药材天然甘味调和口感,以天然抑菌剂复配实现绿色防腐。本发明并通过65~70℃恒温15分钟的特定工艺,激发两种天然抑菌剂的协同抑菌效果,大幅提升口服液储存稳定性,无需额外调酸、调甜或添加其他稳定剂,工艺简便易工业化生产。
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