Electrical pulse generator and medical device for therapeutic treatment and therapeutic treatment method

The integrated generator for pulsed electric fields and direct current fields addresses the inefficiencies of current cancer treatments by concentrating treatment agents or cells in localized areas, enhancing treatment efficacy and reducing hospital stays and side effects.

FR3166804A1Pending Publication Date: 2026-04-03INSTITUT MINES TELECOM TELECOM BRETAGNE
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Patent Information

Application Number
FR2024010528
Authority / Receiving Office
FR · FR
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-10-01
Publication Date
2026-04-03

AI Technical Summary

Technical Problem

Current cancer treatment methods, including surgery, radiotherapy, and chemotherapy, are often ineffective and poorly tolerated, leading to side effects and recurrence due to the lack of a standardized protocol for pulsed electric field technologies like electrochemotherapy and irreversible electroporation.

Method used

A therapeutic treatment generator with integrated direct current and pulsed electric field sources, controlled by a microcontroller, is used to concentrate treatment agents or cells in a localized area by electrotaxy, allowing for versatile and portable treatment protocols.

Benefits of technology

This approach enhances treatment efficacy by improving the permeability of cancer cells to chemotherapeutic agents and selectively targeting malignant cells, reducing hospital stays and side effects while increasing patient comfort and treatment effectiveness.

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Abstract

Electrical pulse generator and therapeutic treatment medical device and therapeutic treatment method. The invention relates to a generator for therapeutic treatment configured to be electrically coupled to an electric field application system inside the body, the generator comprising: - a housing, - a pulsed electric field source in the housing and configured to deliver a pulsed electric field through the electric field application system to a first treatment area, - a DC voltage source in the housing and configured to deliver a DC current to the electric field application system in order to cause objects capable of moving to follow a DC electric field in the body to migrate from a second treatment area to the first treatment area.- an electrical transmission circuit connected to the pulsed electric field generator and the DC voltage source, and configured to electrically couple the pulsed electric field generator and the two sources. Figure for the abbreviation: Fig. 1,
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