Matrix and associated sample or mixing cup used for removing components of a liquid sample

AU2021235877B2Pending Publication Date: 2026-10-15IDEXX LABORATORIES INC
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Patent Information

Application Number
AU2021235877
Authority / Receiving Office
AU · AU
Patent Type
Applications
Current Assignee / Owner
Priority Date
2020-03-09
Filing Date
2021-03-08
Publication Date
2026-10-15
Estimated Expiration
2041-03-08

AI Technical Summary

Technical Problem

Existing methods for removing components like hemoglobin from blood samples are inefficient, affecting the accuracy of measurements in automated chemical analyzers, as they rely on settling particles which require time and may not completely remove interfering components.

Method used

A matrix with immobilized functionalized particles, such as IMAC beads, is integrated into a mixing cup, allowing the blood sample to flow through and adhere to these particles, effectively removing or reducing the concentration of targeted components like hemoglobin before the sample is tested.

Benefits of technology

This approach provides a rapid and complete removal of interfering components, ensuring accurate measurements without the need for settling, and can be used with conventional chemical analyzers and unmodified test slides.

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Abstract

An insert mounted in a mixing cup and used by an automated chemical analyzer for removing a targeted component of a liquid sample includes a porous matrix formed of or carrying in an immobilized state functionalized particles having properties such that the targeted component of the liquid sample adheres to the functionalized particles. When the liquid sample is expelled from a disposable tip fitted on the end of a pipette forming part of the automated chemical analyzer into the mixing cup, the liquid sample is drawn into the matrix of the insert by capillary action, whereupon the targeted component of the liquid sample adheres to the immobilized functionalized particles of the matrix.
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