Small-molecule compound as well as synthesis method and application thereof
By developing a new type of small molecule compound, using specific structural formulas and synthesis methods, we have solved the problem of existing drugs being unable to effectively treat androgenic alopecia, achieved the effect of promoting hair growth and improving the hair growth cycle, and are suitable for many patients. treatment of diseases.
Patent Information
- Application Number
- CN201410398184.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2014-08-14
- Publication Date
- 2014-12-10
- Estimated Expiration
- 2034-08-14
AI Technical Summary
Existing drugs for the treatment of alopecia cannot effectively solve the problem of androgenic alopecia, and there is insufficient research on the diversity and diversification of drugs for regulating hair growth, making them unable to meet the needs of modern people.
A new type of small molecule compound was developed to promote hair growth through a specific structural formula and synthesis method. The specific steps include using 4-methoxyphenol and 1,2,3-trichloro-5-nitrobenzene as The initial raw materials undergo a series of reactions to generate N1-(3,5-dichloro-4-(3-(substituted benzyl)-4-hydroxyphenoxy)phenyl)-N2-oxalylhydroxylamine compounds, which are used for Treating androgenetic alopecia.
This small molecule compound significantly changes the hair growth cycle and promotes hair growth in mouse hair growth tests, has no toxic side effects, slows body weight changes, and has obvious hair growth effects. It is suitable for the treatment of androgenetic alopecia and other diseases such as osteoporosis. disease, obesity, etc.