Hydrogen sulfide donor in organic salt form and preparation method thereof

By using an organic compound with a basic structure and hydrogen sulfide to form a salt structure as a hydrogen sulfide donor, the problem of poor release stability of hydrogen sulfide donors in the body in the prior art is solved, and the release of hydrogen sulfide in the living body is achieved. Rapid release and simplified metabolic process enhance its application value in medical research and drug development.

CN107353232AActive Publication Date: 2017-11-17CHENGDU KAOENSI SCI & TECH
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Patent Information

Application Number
CN201710475428.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2017-06-21
Publication Date
2017-11-17
Estimated Expiration
2037-06-21

AI Technical Summary

Technical Problem

Existing hydrogen sulfide donors have poor stability during in vivo release and require enzymes to participate in complex physiological reactions, which affects their application and research in organisms.

Method used

An organic compound with a basic structure and hydrogen sulfide form a salt structure as a hydrogen sulfide donor in the form of an organic salt to ensure the stable and rapid release of hydrogen sulfide in living organisms.

Benefits of technology

It achieves rapid and stable release of hydrogen sulfide in organisms, simplifies its metabolic process in the body, and enhances its application value in medical research and drug development.

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Abstract

The invention provides a hydrogen sulfide donor in an organic salt form and a preparation method thereof. The hydrogen sulfide donor is a salt structure formed by organic compounds with an alkaline structure and hydrogen sulfide. The structure of the hydrogen sulfide donor is simple. The preparation method is simple and easy to perform. Moreover, hydrogen sulfide donors in different forms can be obtained according to the needs of development and research. After the hydrogen sulfide donor enters an organism, the process of degradation in the organism and hydrogen sulfide supply is simple, rapid, and effective, there is not any requirement on enzyme or other complicated condition, and thus the hydrogen sulfide donor has a wide application prospect and a great application value.
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