Sample analysis apparatus and reaction vessel scheduling method

Abstract

The application discloses a sample analysis device and a reaction container scheduling method. The sample analysis device comprises a transport assembly, the transport assembly comprises a transport vehicle moving along a first preset path, and first and second positions are arranged at intervals on the first preset path, and the transport assembly can simultaneously transport different transport vehicles to the first and second positions. In the sample analysis device provided by the embodiment of the application, the first and second positions are arranged on the preset path, and the transport vehicle is arranged to simultaneously transport a plurality of reaction containers to the first and second positions, so that corresponding operations can be simultaneously performed at the first and second positions, the scheduling and movement path of the gripper are reduced, and the efficiency of sample testing is improved.

Description

Technical Field

[0001] This application relates to the field of medical devices, specifically to a sample analysis device and a reaction vessel scheduling method. Background Technology

[0002] As living standards improve, people have higher and higher requirements for medical technology, leading to a greater demand for biological sample testing.

[0003] In existing sample analysis equipment, a manipulator is used to move samples between different stations within the reaction vessel. This manipulator movement between multiple stations consumes significant internal space and time resources, prolonging sample flow time and distance, and reducing detection efficiency. Adding more manipulators or isolating functional areas would increase the overall size of the instrument. Summary of the Invention

[0004] This application provides a sample analysis device that can reduce the scheduling of grippers, shorten the sample flow distance, and improve detection efficiency.

[0005] In a first aspect, embodiments of this application provide a sample analysis device, including: a transport component, the transport component including transport vehicles moving along a first preset path, a first position and a second position being distributed at intervals along the first preset path, and the transport component being able to simultaneously transport different transport vehicles to the first position and the second position respectively.

[0006] According to one aspect of the embodiments of this application, the first preset path is a straight transportation path extending along a first direction.

[0007] According to one aspect of the embodiments of this application, the first position is a feeding position for loading a reaction vessel into a transport vehicle, and the second position is a sample function position for performing a predetermined operation on the reaction vessel for the transport vehicle. The sample analysis device further includes a container loading area and a sample function area, the container loading area and the first position are correspondingly set, and the sample function area and the second position are correspondingly set.

[0008] According to one aspect of the embodiments of this application, the sample functional area includes a mixing area, and the sample functional position includes a mixing position. The mixing position and the mixing area are correspondingly arranged, and the predetermined operation includes mixing the reaction vessel of the transport vehicle located at the mixing position.

[0009] According to one aspect of the embodiments of this application, the sample functional area further includes a reaction liquid storage area, and the sample functional position includes a liquid filling position. The liquid filling position and the reaction liquid storage area are correspondingly arranged, and the predetermined operation includes injecting a predetermined liquid into the reaction container of the transport vehicle located at the liquid filling position.

[0010] According to one aspect of the embodiments of this application, the reaction liquid storage area includes a sample rack area and a functional liquid area arranged side by side along a second direction, wherein the sample rack area is used to load the sample rack and the functional liquid area is used to store the functional liquid.

[0011] According to one aspect of the embodiments of this application, the number of transport vehicles is at least three, and the transport component can simultaneously transport different transport vehicles to the mixing position, the liquid filling position and the feeding position respectively.

[0012] According to one aspect of the embodiments of this application, the mixing position, the liquid filling position, and the feeding position are arranged sequentially along a first direction.

[0013] According to one aspect of the embodiments of this application, the sample function bit further includes a buffer bit, which is disposed between the liquid filling bit and the mixing bit.

[0014] According to one aspect of the embodiments of this application, the distance H1 between the feed position and the liquid filling position, the distance H2 between the liquid filling position and the buffer position, and the distance H3 between the buffer position and the mixing position satisfy the relationship H1=H2=H3.

[0015] According to one aspect of the embodiments of this application, the transport component further includes a first conveyor belt for driving transport vehicles to move along a first preset path, a plurality of transport vehicles are disposed on the first conveyor belt, and the distance H between two adjacent transport vehicles satisfies the relationship H=H1=H2=H3.

[0016] According to one aspect of the embodiments of this application, it further includes a control mechanism for controlling the first conveyor belt to transport the transport vehicle along a first preset path.

[0017] According to one aspect of the embodiments of this application, the transport control component includes a controller, a first photoelectric sensor disposed at the feeding position, a second photoelectric sensor disposed at the liquid filling position, a third photoelectric sensor disposed at the mixing position, and a first drive device for driving the first conveyor belt to move. The controller is electrically connected to the first photoelectric sensor, the second photoelectric sensor, the third photoelectric sensor and the first drive device respectively, so as to control the first drive device to drive the movement of the first conveyor belt according to the sensing signals of the first photoelectric sensor, the second photoelectric sensor and the third photoelectric sensor.

[0018] According to one aspect of the embodiments of this application, the mixing zone includes: a first mixing module for mixing a predetermined liquid in a reaction vessel located in a mixing position within a transport vehicle.

[0019] According to one aspect of the embodiments of this application, a reaction vessel contains magnetic beads, and a first mixing module has a magnetic component that can move along a third preset path. The magnetic component moves along the third preset path to drive the magnetic beads to move within the reaction vessel to mix the liquid within the reaction vessel.

[0020] According to one aspect of the embodiments of this application, it further includes a detection zone, which and the mixing zone are disposed on opposite sides of the transport component in a second direction, and the detection zone and the reaction liquid storage zone are located on the same side of the transport component. The detection zone includes a detection module for detecting the characteristics of the sample in the reaction vessel.

[0021] According to one aspect of the embodiments of this application, the detection module includes a magnetic bead detection module and an optical detection module arranged side by side along a second direction, wherein the magnetic bead detection module is located on the side of the optical detection module facing the first mixing module.

[0022] According to one aspect of the embodiments of this application, the detection area further includes an incubation module arranged side by side with the first mixing module and the detection module along the second direction, the incubation module being located on the side of the detection module facing the first mixing module.

[0023] According to one aspect of the embodiments of this application, the detection area further includes a second mixing module, which is located between the incubation module and the detection module.

[0024] According to one aspect of the embodiments of this application, it further includes a reagent area for storing reagents that react with the sample, and the reagent area is located between the detection area and the reaction solution storage area.

[0025] According to one aspect of the embodiments of this application, the reagent area includes a first reagent area and a second reagent area arranged side by side along a first direction.

[0026] According to one aspect of the embodiments of this application, the container loading area is provided with a container loading device, which includes a container feeding channel for conveying new reaction containers. The container feeding channel is located on the upper side of the transport component, and one end of the container feeding channel has an outlet. The reaction container can be moved out of the container feeding channel from the outlet. A transport block is used to cooperate with the outlet and to receive new reaction containers from the outlet. It can move along a second preset path to transport the new reaction containers to a transport vehicle located at the feeding position.

[0027] According to one aspect of the embodiments of this application, the transport block can be moved to the receiving position and dock with the outlet to receive the reaction container from the outlet. After receiving the reaction container, the transport block can move along a second preset path and cause the reaction container to slide out of the transport block and fall into the transport vehicle.

[0028] Secondly, embodiments of this application also provide a reaction container scheduling method, using the sample analysis equipment as described above, the transport vehicle including a first transport vehicle and a second transport vehicle, the method including controlling the transport component to transport the first transport vehicle to a first position while simultaneously transporting the second transport vehicle to a second position; loading a new reaction container into the first transport vehicle, and performing a predetermined operation on the reaction container in the second transport vehicle of the sample function position when there is a reaction container in the second transport vehicle of the sample function position.

[0029] According to one aspect of the embodiments of this application, the second position includes a mixing position, and when there is a reaction vessel in the transport vehicle of the mixing position, a mixing operation is performed on the reaction vessel of the mixing position based on a mixing command.

[0030] Thirdly, this application also provides another reaction vessel scheduling method, using the sample analysis equipment as described above. The transport vehicle further includes a first transport vehicle, a second transport vehicle, and a third transport vehicle. The second position includes a liquid filling position and a mixing position. The method includes controlling the transport component to transport the first transport vehicle to the feeding position while simultaneously transporting the second transport vehicle to the liquid filling position and the third transport vehicle to the mixing position. A new reaction vessel is loaded into the first transport vehicle. If there is a reaction vessel in the second transport vehicle at the liquid filling position, a predetermined liquid is added to the reaction vessel in the second transport vehicle at the liquid filling position. If there is a reaction vessel in the third transport vehicle at the mixing position, a mixing operation is performed on the reaction vessel in the third transport vehicle at the mixing position.

[0031] Fourthly, this application also provides another reaction vessel scheduling method, using the sample analysis equipment as described above. The transport vehicle further includes a first transport vehicle, a second transport vehicle, a third transport vehicle, and a fourth transport vehicle. The second sample location includes a liquid filling position, a buffer position, and a mixing position arranged at intervals. The method includes controlling the transport component to transport the first transport vehicle to the first location while simultaneously transporting the second transport vehicle to the liquid filling position, the third transport vehicle to the buffer position, and the fourth transport vehicle to the mixing position. A new reaction vessel is loaded into the first transport vehicle. If there is a reaction vessel in the second transport vehicle at the liquid filling position, a predetermined liquid is added to the reaction vessel in the second transport vehicle at the liquid filling position. If there is a reaction vessel in the fourth transport vehicle at the mixing position, a mixing operation is performed on the reaction vessel in the fourth transport vehicle at the mixing position.

[0032] According to the sample analysis device of this application embodiment, by setting a first position and a second position on a preset path, and setting a transport vehicle to transport multiple reaction containers to the first position and the second position at the same time, corresponding operations can be performed at the first position and the second position simultaneously, reducing the scheduling of grippers and movement paths, and improving the efficiency of sample testing. Attached Figure Description

[0033] Other features, objects, and advantages of this application will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings, in which the same or similar reference numerals denote the same or similar features, and the drawings are not drawn to scale.

[0034] Figure 1 A schematic diagram of the sample analysis device provided in the embodiments of this application;

[0035] Figure 2 A schematic diagram of a container loading device provided for an embodiment of this application;

[0036] Figure 3 Another schematic diagram of the container loading device provided for an embodiment of this application;

[0037] Figure 4 A schematic diagram of a transport block provided for an embodiment of this application;

[0038] Figure 5 Another schematic diagram of the container loading device provided for an embodiment of this application;

[0039] Figure 6 A schematic diagram of a limiting mechanism provided for an embodiment of this application;

[0040] Figure 7 A schematic diagram of a stop provided in an embodiment of this application;

[0041] Figure 8 A schematic diagram of a reaction vessel feed channel provided for an embodiment of this application;

[0042] Figure 9 A schematic diagram of a container handling mechanism provided for an embodiment of this application;

[0043] Figure 10 A schematic diagram of a method for circulating a reaction vessel according to an embodiment of this application;

[0044] Figure 11 A schematic diagram of a method for scheduling reaction vessels provided for embodiments of this application;

[0045] Figure 12 A schematic diagram of a method for scheduling reaction vessels provided for another embodiment of this application;

[0046] Figure 13 A schematic diagram of a method for scheduling reaction vessels provided in yet another embodiment of this application. Detailed Implementation

[0047] The features and exemplary embodiments of various aspects of the present invention will now be described in detail. To make the objectives, technical solutions, and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are only configured to explain the present invention and are not configured to limit the present invention. For those skilled in the art, the present invention can be practiced without some of these specific details. The following description of the embodiments is merely intended to provide a better understanding of the present invention by illustrating examples of the invention.

[0048] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising..." does not exclude the presence of additional identical elements in the process, method, article, or apparatus that includes the element.

[0049] It should be understood that when describing the structure of a component, when referring to a layer or region as being "above" or "on top of" another layer or region, it can mean that it is directly above the other layer or region, or that it contains other layers or regions between it and the other layer or region. Furthermore, if the component is flipped over, that layer or region will be located "below" or "under" the other layer or region.

[0050] The features and exemplary embodiments of various aspects of the present invention will now be described in detail. Furthermore, the features, structures, or characteristics described below may be combined in any suitable manner in one or more embodiments.

[0051] This application provides a sample analysis device. The sample analysis device of this application embodiment will be described in detail below with reference to the accompanying drawings.

[0052] Please see Figure 1 and Figure 2 , Figure 1 This is a schematic diagram of the structure of a sample analysis device 1 provided according to an embodiment of this application; Figure 2 A schematic diagram of a container loading device 60 provided in an embodiment of this application;

[0053] The sample analysis device in this application embodiment is used to analyze biochemical samples. Existing sample analysis devices often use robotic arms to manage multiple samples. However, as the number of samples increases, the robotic arm's management often struggles to keep up with efficiency. Therefore, this application designs a sample analysis device that rationally allocates and sets up the sample handling process, from sample loading and reaction vessel scheduling to sample addition, mixing, incubation, and detection. A transport component then moves the reaction vessel and reaction samples between these operations. This effectively reduces the amount of robotic arm work and improves the efficiency of analysis and detection.

[0054] like Figure 1 and Figure 2 As shown, the sample analysis device 1 provided in this application includes a transport component 10, which includes a transport vehicle 101 moving along a first preset path A. First positions 102 and second positions 103 are distributed at intervals along the first preset path A. The transport component 10 can simultaneously transport different transport vehicles 101 to the first position 102 and the second position 103 respectively. By setting multiple transport vehicles 101 to circulate between the first position 102 and the second position 103, it is possible to simultaneously operate the reaction vessel 2 or the sample in the transport vehicle 101 at the first position 102 and the second position 103, thereby improving efficiency.

[0055] In some embodiments of this application, the first preset path A is a straight transport path extending along the first direction X, which can simplify the shape of the first preset path A and speed up the transport efficiency of the transport vehicle 101. Figure 1 The direction of the first preset path A is indicated by a double-headed arrow, but the size of the first preset path A is not indicated.

[0056] In some embodiments of this application, the first position 102 is a feeding position for loading the reaction container 2 into the transport vehicle 101, and the second position 103 is a sample function position for performing predetermined operations on the reaction container 2 used in the transport vehicle 101. The sample analysis device 1 also includes a container loading area 20 and a sample function area 30. The container loading area 20 is correspondingly set to the first position 102, and the sample function area 30 is correspondingly set to the second position 103. The reaction container 2 is a consumable in sample analysis and needs to be replenished in a timely manner. By setting the feeding position for loading the reaction container 2 at the first position 102, timely replenishment of the reaction container 2 can be achieved. By setting the sample function area 30 at the second position 103, corresponding sample operations can be performed while loading the reaction container 2 without affecting the loading of the reaction container 2, effectively improving the efficiency of the reaction container 2's circulation.

[0057] In some embodiments of this application, the sample functional area 30 includes a mixing area 301, and the sample functional position includes a mixing position 104, with the mixing position 104 and the mixing area 301 correspondingly arranged. A predetermined operation includes mixing the reaction vessel 2 of the transport vehicle 101 located at the mixing position 104. Mixing operations are frequently required in sample analysis; setting a predetermined operation enables automatic mixing of the sample in the mixing area 301.

[0058] In some embodiments of this application, the sample functional area 30 further includes a reaction solution storage area 302, and the sample functional position includes a liquid dispensing position 105. The liquid dispensing position 105 and the reaction solution storage area 302 are correspondingly arranged. The predetermined operation includes injecting a predetermined liquid into the reaction container 2 of the transport vehicle 101 located at the liquid dispensing position 105. The reaction solution storage area 302 generally stores the reaction solution and the sample. The liquid dispensing position 105 corresponding to the reaction solution storage area 302 facilitates the dispensing of liquid, reduces the distance traveled by the aspiration needle, and improves detection efficiency. For example, it facilitates the direct transfer of reaction liquid from the reaction solution storage area 302 to the adjacent liquid dispensing position 105 for operation.

[0059] In some embodiments of this application, the reaction solution storage area 302 includes a sample rack area 304 and a functional solution area 303 arranged side by side along the second direction Y. The sample rack area 304 is used to load sample racks, and the functional solution area is used to store functional solutions. The functional solutions are, for example, diluents or buffer solutions.

[0060] In some embodiments of this application, the number of transport vehicles 101 is at least three, and the transport assembly 10 can simultaneously transport different transport vehicles 101 to the mixing position 104, the liquid filling position 105, and the feeding position (i.e., the first position 102). The three transport vehicles 101 operate simultaneously, so that the container loading, liquid filling, and sample mixing operations are performed simultaneously.

[0061] In some embodiments of this application, the mixing position 104, the liquid filling position 105, and the feed position are sequentially arranged along the first direction X. The sample operation process generally involves loading the reaction vessel 2, adding the corresponding sample liquid and / or functional liquid to the reaction vessel 2 to prepare the sample, and finally mixing the sample. The corresponding functional positions are arranged sequentially according to the above process to form a streamlined operation, which effectively improves the efficiency of sample analysis operations.

[0062] In some embodiments of this application, the sample function bit also includes a buffer bit 106, which is located between the liquid filling bit 105 and the mixing bit 104.

[0063] In the above embodiment, by adding the buffer position 106, the distance between the liquid filling position 105 and the detection area 40 can be increased, so that different reagents are not interfered with when adding them to the reaction vessel 2 at different locations. For example, Figure 1 As shown, the sample functional area 30 includes a reagent area 50, which includes a first reagent area 501 located near the mixing area 301 and the detection area 40, and a second reagent area 502 located near the liquid filling position 105. A buffer position 106 is provided to ensure that the mixing position 104, the detection area 40, the mixing area 301, and the liquid filling position 105 are far apart in the first direction X. When it is necessary to simultaneously add liquid to the reaction vessel 2 containing the mixing area 301, the detection area 40, or the mixing position 104, and the reaction vessel 2 containing the liquid filling position 105, the reagent liquid located in the first reagent area 501 can be added to the reaction vessel 2 containing the mixing area 301, the detection area 40, or the mixing position 104, and the reagent liquid located in the second reagent area 502 can be added to the liquid filling position 105. This ensures that the paths of the pipettes used to draw reagent liquid from the first reagent area 501 and the pipettes used to draw reagent liquid from the second reagent area 502 do not interfere with each other. Sample liquid can be added to reaction vessel 2 at liquid filling position 105. In some embodiments of this application, the distances H1 between the feed position and liquid filling position 105, H2 between liquid filling position 105 and buffer position, and H3 between buffer position and mixing position 104 satisfy the relationship H1 = H2 = H3. The equal distances between multiple positions facilitate the simultaneous transport of reaction vessel 2 or sample to the corresponding positions by the corresponding transport vehicle 101, improving operational convenience.

[0064] In some embodiments of this application, the transport component 10 further includes a first conveyor belt 107 for driving the transport vehicles 101 along a first preset path A. Multiple transport vehicles 101 are disposed on the first conveyor belt 107, and the distance H between two adjacent transport vehicles 101 satisfies the relationship H = H1 = H2 = H3. The transport vehicles 101 on the first conveyor belt 107 correspond to various positions in the sample function positions. When the distance H between two adjacent transport vehicles 101 satisfies the relationship H = H1 = H2 = H3, moving the first conveyor belt 107 by the same distance is sufficient to move the multiple transport vehicles 101 as a whole to the next sample function position, achieving the purpose of moving multiple transport vehicles 101 in a single operation.

[0065] In some embodiments of this application, a control mechanism (not shown in the figures) is also included. The control mechanism is used to control the first conveyor belt 107 to transport the transport vehicle 101 along the first preset path A. The control mechanism can control the moving speed of the first conveyor belt 107, and thus control the moving speed of the transport vehicle 101, so that the reaction vessel 2 of the transport vehicle 101 can move at a suitable speed and be detected.

[0066] In some embodiments of this application, the control mechanism includes a controller, a first photoelectric sensor 108 located at the feeding position, a second photoelectric sensor 109 located at the liquid filling position 105, a third photoelectric sensor 110 located at the mixing position 104, and a first driving device for moving the first conveyor belt 107. The controller is electrically connected to the first photoelectric sensor 108, the second photoelectric sensor 109, the third photoelectric sensor 110, and the first driving device, respectively, to control the first driving device to drive the movement of the first conveyor belt 107 based on the sensing signals from the first photoelectric sensor 108, the second photoelectric sensor 109, and the third photoelectric sensor 110. By setting up the control mechanism, the accuracy and efficiency of the transport assembly 10 are improved.

[0067] In some embodiments of this application, the mixing zone 301 includes a first mixing module 305 for mixing a predetermined liquid in a reaction vessel 2 located in a transport vehicle 101 at the mixing position 104.

[0068] In some embodiments of this application, the reaction container 2 contains magnetic beads, and the first mixing module 305 has a magnetic component that can move along a third preset path. The magnetic component moves along the third preset path to drive the magnetic beads to move within the reaction container 2, thereby mixing the liquid within the reaction container 2. By setting the first mixing module 305, when the reaction container 2 follows the transport vehicle 101 and the transport vehicle 101 is located on the first preset path A, the liquid within the reaction container 2 can be mixed by the first mixing module 305 without having to transfer the reaction container 2 from the transport vehicle 101 to other locations, which can effectively improve the efficiency of sample analysis.

[0069] In some embodiments of this application, the sample functional area 30 further includes a detection area 40. The detection area 40 and the mixing area 301 are respectively disposed on opposite sides of the transport component 10 in the second direction Y, and the detection area 40 and the reaction liquid storage area 302 are located on the same side of the transport component 10. The detection area 40 includes a detection module for detecting the characteristics of the sample in the reaction container 2. By setting the detection area 40, the reagents that have been mixed in the mixing area 301 can be detected. The detection area 40 and the mixing area 301 are respectively disposed on opposite sides of the transport component 10 in the second direction Y. On the one hand, this simplifies the layout of the modules on the sample analysis device 1 and reduces the space occupied by the sample analysis device 1. On the other hand, it also reduces the distance between the mixing area 301 and the detection area 40, facilitating the rapid transfer of the reaction container 2 in the mixing area 301 to the detection area 40 for detection, which can effectively improve the flow efficiency of the reaction container 2. In addition, it can reduce the distance between the detection area 40 and the first preset path A, making it easier to quickly transfer the reaction container 2 located in the transport vehicle 101 on the first preset path A to the detection area 40 for detection, thereby further improving the flow efficiency of the reaction container 2.

[0070] In some embodiments of this application, the detection module includes a magnetic bead detection module 401 and an optical detection module 402 arranged side by side along the second direction Y, with the magnetic bead detection module 401 located on the side of the optical detection module 402 facing the first mixing module 305. The detection module includes two different magnetic bead detection modules 401 and optical detection modules 402, which can enrich the detection functions of the sample analysis device 1.

[0071] In some embodiments of this application, the detection area 40 further includes an incubation module 403 arranged side-by-side with the first mixing module 305 and the detection module along the second direction Y. The incubation module 403 is located on the side of the detection module facing the first mixing module 305. The incubation module 403 has an incubation position for placing the reaction container 2 and is used to incubate the sample. The incubation module 403 has a heating function for heating the sample and reagents in the reaction container 2 to achieve the incubation function. For example, the incubation module 403 can heat the sample and reagents to approximately 37°C before formal measurement to ensure that the reaction proceeds normally. The reaction container 2 incubated by the incubation module 403 can then be detected by the detection module.

[0072] In some embodiments of this application, the detection zone 40 further includes a second mixing module 404, which is located between the incubation module 403 and the detection module. By adding the second mixing module 404, the first mixing module 305 and the second mixing module 404 can perform mixing operations simultaneously, improving mixing efficiency. Furthermore, the location of the second mixing module 404 between the incubation module 403 and the detection module reduces the distance between them, facilitating the rapid transfer of the mixed reaction vessel 2 to the detection module and effectively improving the flow rate of the reaction vessel 2.

[0073] In some embodiments of this application, the sample functional area 30 further includes a reagent area 50. The reagent area 50 is used to store reagents that react with the sample. The reagent area 50 is used to add reagents to the reaction container 2 in the incubation module 403 and / or the transport vehicle 101 on the first preset path A. The reagent area 50 is located between the detection area 40 and the reaction solution storage area 302. When analyzing the sample in the reaction container 2, it is usually necessary to add reagents to the sample. Placing the reagents between the detection area 40 and the reaction solution storage area 302 can reduce the distance between the reagent area 50 and the detection area 40, making it easier to quickly add reagents to the reaction container 2 in the detection area 40, thereby improving the working efficiency of the sample analysis device 1.

[0074] In some embodiments of this application, the reagent area 50 includes a first reagent area 501 and a second reagent area 502 arranged side-by-side along a first direction X. When samples need to undergo different experiments, different reagents are usually added to the samples, and the first reagent area 501 and the second reagent area 502 can be used to store different reagents. The first reagent area 501 is located near the incubation module 403, for example, the first reagent area 501 is used to store reagents added to the incubation module 403. The second reagent area 502 is located near the liquid dispensing position 105, and the second reagent area 502 is used to store reagents added to the liquid dispensing position 105. Separating the two reagent areas facilitates the addition of reagents to adjacent positions, shortens the distance the pipette needle moves, and improves efficiency.

[0075] This application also provides a container loading device 60. See also... Figure 2 , Figure 2 This application provides a container loading device 60.

[0076] Please refer to the reference. Figure 1 as well as Figure 2 In some embodiments of this application, a container loading device 60 may be disposed in the container loading area 20. The container loading device 60 includes a feed channel 601 for conveying new reaction containers 2. The feed channel 601 is disposed on the upper side of the transport assembly 10. One end of the feed channel 601 has an outlet 602, through which the reaction container 2 can be moved out of the feed channel 601. A conveying block 603 cooperates with the outlet 602 and is used to receive new reaction containers 2 from the outlet 602. It can move along a second preset path B to transport the new reaction containers 2 to the transport vehicle 101 located at the feeding position. The container loading device 60 enables automatic loading of the reaction containers 2, which can effectively improve the turnover efficiency of the reaction containers 2.

[0077] In some embodiments of this application, such as Figure 3 As shown, the transport block 603 can move to the receiving position 604 and dock with the outlet 602 to receive the reaction container 2 from the outlet 602. After receiving the reaction container 2, the transport block 603 can move along the second preset path B and allow the reaction container 2 to slide out of the transport block 603 and fall into the transport vehicle 101. By setting the transport block 603, the reaction container 2, which is located at a high position, is moved to a low position, realizing the full automation of loading the reaction container 2 and improving the efficiency of sample analysis operations. In addition, the reaction container can automatically fall into the transport vehicle 101 while following the movement of the transport block 603, which is simple and convenient to operate and can also effectively improve the transportation efficiency of the reaction container C. Compared with the gripper mechanism that requires a robotic arm, the transport block is more flexible in its setting and occupies a smaller volume, which helps to reduce the size of the instrument.

[0078] On the other hand, embodiments of this application also provide a reaction vessel transfer device, such as... Figure 3 As shown, this is used to load the reaction container 2 in the sample analysis device 1. Specifically, the reaction container 2 transfer device includes: a feeding mechanism 80, including a feeding channel 601 for transporting the reaction container 2 and a container transfer mechanism 90. One end of the feeding channel 601 is provided with an outlet 602, through which the reaction container 2 can be moved out of the feeding channel 601; the container transfer mechanism 90 includes a transfer block 603 movable to a receiving position 604 to dock with the outlet 602 to receive the reaction container 2 from the outlet 602; and a transport vehicle 101 for receiving and transporting the reaction container 2 from the transfer block 603; wherein, after receiving the reaction container 2 from the outlet 602, during the process of moving along the second preset path B, the transfer block 603 can cause the reaction container 2 to slide out of the transfer block 603 and fall into the transport vehicle 101 located at a predetermined position.

[0079] In the reaction container 2 transfer device of this application embodiment, the reaction container 2 is provided by a feeding mechanism 80, and a container transfer mechanism 90 is provided between the feeding channel 601 and the transport vehicle 101 at a predetermined position. The container transfer mechanism 90 moves along the second preset path B to move the reaction container 2 from the feeding mechanism 80 to the transport vehicle 101, so that the reaction container 2 moves automatically between the feeding channel 601 and the sample functional area 30, realizing the automatic loading of the reaction container 2, increasing the throughput of samples in the analysis device, and improving the efficiency of sample analysis.

[0080] In some embodiments of this application, such as Figure 4 As shown, the transfer block 603 has a receiving cavity 607 for receiving the reaction vessel 2 from the outlet 602. The receiving cavity 607 has a receiving opening that aligns with the outlet 602, and the receiving cavity 607 is used to receive the reaction vessel 2 removed from the outlet 602. By providing the receiving cavity 607 and the receiving opening, after the transfer block 603 moves to the receiving position 604 where the outlet 602 and the receiving opening align, the reaction vessel 2 can enter the receiving cavity 607 from the receiving opening, achieving a smooth transition of the reaction vessel 2.

[0081] In some embodiments of this application, such as Figure 4 As shown, the transport block 603 includes a connecting block 605 and a pair of cantilever arms 606 protruding from the connecting block 605 and arranged opposite to each other. The cantilever arms 606 and the connecting block 605 form a cup-receiving cavity 607, and the space between the ends of the pair of cantilever arms 606 forms a cup-receiving opening. By setting the cantilever arms 606 to form the cup-receiving opening, the structure is simple, the transportation is stable, and the installation is convenient.

[0082] In some embodiments of this application, the feed channel 601 has first suspension surfaces on both sides for suspending the ears of the reaction container 2, and a pair of cantilever arms 606 each have second suspension surfaces 610 located on both sides of the receiving cavity 607 for suspending the ears of the reaction container 2. When the transport block 603 moves to the receiving position 604, the first suspension surfaces and the second suspension surfaces 610 are smoothly connected to form a continuous sliding surface for the ears of the reaction container 2 to slide. The second suspension surfaces 610 provide a stable and rapid sliding channel for the ears to slide while also providing guidance and positioning for the reaction container 2.

[0083] In some embodiments of this application, the transport vehicle 101 has a wall portion that encloses a cavity with an upward-facing opening for accommodating the reaction vessel 2. The wall portion of the transport vehicle 101 can provide a second-direction restraint for the reaction vessel 2, ensuring the stability of the reaction vessel 2 during transport.

[0084] Optional, such as Figure 2 As shown, the transport vehicle 101 includes a first sidewall and a second sidewall arranged opposite each other along the second direction Y, wherein the first sidewall is located on the side of the second sidewall away from the outlet in the second direction Y. A guide plate 101a is provided on the side of the first sidewall facing the outlet. When the transfer block 603 moves the reaction container 2 toward the transport vehicle 101, the bottom of the reaction container 2 is stopped by the guide plate 101a on the side facing the second sidewall. During the downward movement of the reaction container 2 by the transfer block 603, the guide plate 101a can provide a limit along the second direction Y to the reaction container C, ensuring that the reaction container C falls into the transport vehicle 101.

[0085] In some embodiments of this application, such as Figure 5 As shown, a transfer position 608 is provided on the second preset path B. The reaction container 2, which moves from the receiving position 604 to the transfer position 608 on the transfer block 603, enters the cavity of the transport vehicle 101 located at a predetermined position. The wall provides a second direction Y-direction limit to the reaction container 2 located in the cavity. When the reaction container 2 is suspended on the transfer block 603, and the transfer block 603 moves from the receiving position 604 to the transfer position 608, a part of the reaction container 2 can fall into the cavity of the transport vehicle 101. The transport vehicle 101 can provide a second direction Y-direction limit to the reaction container 2, so that the reaction container 2 slides off the transfer block 603 and falls into the transport vehicle 101, completing the automatic loading of the reaction container 2.

[0086] In some embodiments of this application, as the transport block 603 moves from the transfer position 608 along the second preset path B, the reaction container 2 can move along the second suspension surface 610 toward the cup opening under the limiting action of the wall, until the reaction container 2 completely slides out of the cup cavity 607 and falls into the cavity. During the falling process, the displacement of the reaction container 2 along with the movement of the transport block 603 in the second direction Y is restricted by the wall, and vertically it moves downward into the cavity of the transport vehicle 101 along with the movement of the transport block 603.

[0087] In some embodiments of this application, a stop surface 609 is provided on the side of the receiving cavity 607 facing the connecting block 605. The stop surface 609 is used to restrict the reaction container 2 from moving toward the connecting block 605 during movement. When the transfer block 603 moves to the receiving position 604, the reaction container 2 moves from the first suspension surface to the second suspension surface 610 to enter the receiving cavity 607. During the movement of the reaction container 2, the stop surface 609 can provide a limit to the reaction container 2, preventing the reaction container 2 from continuing to move along the second direction Y after entering the receiving cavity 607, so that the reaction container 2 can be accurately positioned in the receiving cavity 607. In addition, during the process of the transfer block 603 moving from the receiving position 604 to the transfer position 608, the stop surface 609 can also provide a limit to the reaction container 2, preventing the reaction container 2 from moving along the second direction Y, so that the reaction container 2 can move along the third direction Z and accurately fall into the transport vehicle 101.

[0088] In some embodiments of this application, the sample analysis device 1 further includes a limiting mechanism 70 for limiting the reaction vessel 2 at the outlet 602. The limiting mechanism 70 has a blocking position that blocks the reaction vessel 2 located at the outlet 602 and a non-blocking position that allows the reaction vessel 2 located at the outlet 602 to pass through. During the process of the transport block 603 moving to the receiving position 604 and docking with the outlet 602, the limiting mechanism 70 can be driven to move from the blocking position to the non-blocking position. When the transport block 603 has not yet moved to the receiving position 604, the limiting mechanism 70 is in the blocking position to prevent the reaction vessel 2 from accidentally slipping. When the transport block moves to the receiving position 604, the limiting mechanism can be set to the non-blocking position, allowing the reaction vessel 2 to move from the outlet 602 onto the transport block 603, completing the automatic loading of the reaction vessel 2. When the transfer block 603 moves the reaction vessel 2 away from the outlet 602, the limiting mechanism 70 is in the blocking position and is used to limit the subsequent new reaction vessel 2, ensuring that the transfer block 603 can only move one reaction vessel 2 at a time.

[0089] In some embodiments of this application, such as Figure 6 and Figure 7As shown, the limiting mechanism 70 includes a stop 701, which has a blocking surface 702 that blocks the reaction vessel 2 located at the outlet position. The stop 701 is movable between a blocking position and a non-blocking position. The limiting mechanism 70 switches between the blocking position and the non-blocking position by moving the stop 701.

[0090] In some embodiments of this application, the limiting mechanism 70 further includes a connector 703 for connection to the outlet of the feed channel 601. Optionally, the connector 703 may also be connected to the outlet of other channels to provide limiting for the reaction vessel 2 in other channels.

[0091] In some embodiments of this application, the reaction vessel 2 on the feed channel 601 moves along the second direction Y, and the stop 701 is slidably disposed relative to the connecting member 703 along the third direction Z, wherein the second direction Y intersects the third direction Z. The component to be transported can be the reaction vessel 2. This application uses the reaction vessel 2 as an example to illustrate the process of transporting the component.

[0092] In some embodiments of this application, the connector 703 includes a mounting portion 704 and a suspended portion 705. The mounting portion 704 has a first end and a second end opposite each other along a third direction Z. The first end is used to connect to the outlet (i.e., the cup outlet 602), and the suspended portion 705 is connected to the second end and suspended above the cup outlet 602. A stop member 701 is slidably connected to the suspended portion 705. In these embodiments, the suspended portion 705 is suspended above the cup outlet 602, and the stop member 701 is slidably connected to the suspended portion 705. When the stop member 701 slides along a third direction Z, the stop member 701 can stop at the cup outlet 602, causing the limiting mechanism 70 to be in a blocked position, or the stop member 701 can be moved away from the cup outlet 602, allowing the reaction vessel 2 to be moved out of the cup outlet 602, causing the limiting mechanism 70 to be in a non-blocking position.

[0093] In some embodiments of this application, the stop 701 includes a connecting rod 706 and a sliding block 707. The connecting rod 706 is connected to the suspended portion 705 and extends in the third direction Z. The sliding block 707 is connected to the connecting rod 706 and is movably disposed relative to the connecting rod 706 in the third direction Z. The side of the sliding block 707 facing the outlet is a blocking surface 702. When the sliding block 707 moves along the connecting rod 706, the sliding block 707 causes the blocking surface 702 to block at the outlet 602, causing the limiting mechanism 70 to be in the blocking position. Alternatively, the sliding block 707 causes the blocking surface 702 to move away from the outlet 602, allowing the reaction vessel 2 to be moved out of the outlet 602, causing the limiting mechanism 70 to be in the non-blocking position.

[0094] In some embodiments of this application, the stop 701 further includes a reset member, which is disposed on the connecting rod 706 and abuts against the suspended portion 705 and the sliding block 707. The reset member has a reset force in the third direction Z. During the process of the transport block 603 moving to the receiving cup position 604, the transport block 603 can drive the sliding block 707 to move the blocking surface 702 away from the cup outlet 602. At this time, the transport block 603 can provide support to the sliding block 707, so that the limiting mechanism 70 is in the blocking position. When the transport block 603 moves the reaction vessel 2 away from the receiving cup position 604, the transport block 603 can no longer provide support to the sliding block 707. Under the reset action of the reset member, the sliding block 707 can return to its original position, so that the sliding block 707 can move the blocking surface 702 to block at the cup outlet 602, so that the limiting mechanism 70 is in the blocking position. Therefore, by setting a reset element, the limiting mechanism 70 can be promptly placed in the blocking position. The limiting mechanism 70 can only release one reaction vessel 2 at a time. After the transport block 603 moves the reaction vessel 2 away from the receiving position 604, the limiting mechanism 70 will not release the reaction vessel 2. There are several ways to set the reset element. For example, the reset element can be a spring. Optionally, the spring can be sleeved on the connecting rod 706.

[0095] In some embodiments of this application, there are two connecting rods 706, which are spaced apart from each other on the suspended portion 705. By providing two connecting rods 706, the stability of the relative position between the sliding block 707 and the suspended portion 705 can be ensured.

[0096] In some embodiments of this application, the sliding block 707 has a recessed surface opposite to the suspended portion 705 to form a receiving cavity 708. An opening is provided on the blocking surface 702 for the reaction container 2 to pass through. This opening communicates with the receiving cavity 708, allowing the reaction container 2 to enter the receiving cavity 708 through the opening and eventually exit the sliding block 707 from the receiving cavity 708. When the transfer block 603 moves to the receiving position 604, the opening on the blocking surface 702 for the reaction container 2 to pass through aligns with the outlet 602, allowing the reaction container 2 to enter the receiving cavity 708 through the opening and eventually exit the sliding block 707 from the receiving cavity 708.

[0097] In some embodiments of this application, the receiving cavity 708 has a limiting surface 709 facing the reaction vessel 2, and a first side surface 710 and a second side surface 711 disposed on both sides of the limiting surface 709. The first side surface 710 and the second side surface 711 can provide limiting for the reaction vessel 2, preventing the reaction vessel 2 from shaking when it enters the receiving cavity 708 through the opening.

[0098] In some embodiments of this application, the sliding block 707 is provided with a clearance slope 712 on the side facing the outlet. The clearance slope 712 is provided on the side of the blocking surface 702 away from the suspended part 705. The clearance slope 712 is used to prevent the stop member 701 from being accidentally pushed into the reaction container 2 on the channel 601 during the downward movement.

[0099] In some embodiments of this application, the blocking surface 702 and the yielding slope 712 are disposed on the surface of the sliding block 707 facing the outlet, and the yielding slope 712 is inclined away from the outlet in the direction from the blocking surface 702 to the yielding slope 712, and the opening communicating with the receiving cavity 708 is disposed on the yielding slope 712. When the yielding slope 712 is inclined in the above-mentioned direction, when the blocking surface 702 is in contact with the surface of the connector 703, there is a gap between the yielding slope 712 and the outlet 602, which can prevent accidental pushing into the reaction vessel 2 on the channel 601. That is, after the first reaction vessel 2 in the feed channel 601 is taken away by the transfer block 603, the front part of the next reaction vessel 2 (the current first reaction vessel 2 in the feed channel 601) may exceed the outlet of the feed channel 601. Since the relief slope 712 is inclined from top to bottom towards the outside of the outlet, during the descent of the relief slope 712, since there is a sufficient gap between the bottom edge of the relief slope 712 and the outlet, its bottom edge will avoid the part of the reaction vessel 2 that exceeds the outlet. As the relief slope 712 continues to descend, this gap becomes smaller and smaller. Thus, under the guiding action of the relief slope 712, the part of the reaction vessel 2 that exceeds the outlet will be pushed back into the feed channel 601.

[0100] In some embodiments of this application, the side of the stop 701 facing the bottom of the outlet 602 is recessed to form a groove. When the transport block 603 is engaged with the stop 701, the groove and the receiving cavity 607 form a receiving cavity for accommodating the reaction vessel 2. The receiving cavity provides a passage for the ear of the reaction vessel 2 to pass through.

[0101] In the reaction vessel 2 transfer device provided in this application, in the initial loading state of the reaction vessel 2, the reaction vessels 2 are arranged sequentially along the second direction Y in the feed channel 601, and the transport vehicle 101 is located directly below the receiving cup position 604. At this time, the transport vehicle 101 is in the feeding position. The limiting mechanism 70 is in the blocking position, and the sliding block 707, under the reset action of the reset member, drives the blocking surface 702 to block at the outlet 602, preventing the reaction vessel 2 from sliding down from the outlet 602. The adjusting block 603 has not yet moved to the receiving cup position 604. During the loading process of the reaction vessel 2, when the adjusting block 603 moves to the receiving cup position 604, the adjusting block 603 abuts against the bottom of the sliding block 707 and drives the sliding block 707 to move along the connecting rod 706 to above the outlet 602. The sliding block 707 drives the blocking surface 702 to move away from the outlet 602, and the limiting mechanism 70 is in the non-blocking position. At this time, the second suspension surface 609 of the transfer block 603 aligns with the first suspension surface of the feed channel 601, and the reaction container 2 slides from the outlet 602 into the receiving cavity formed by the receiving cavity 708 and the receiving cavity 607, thus suspending the reaction container 2 on the cantilever 606. Then, the transfer block 603 moves the reaction container 2 downwards or diagonally downwards. When the transfer block 603 moves to the transfer position 608, the bottom of the reaction container 2 enters the transport vehicle 101, which provides a limit to the reaction container 2. As the transfer block 603 continues to move, the reaction container 2 can slide from the transfer block 603 into the transport vehicle 101, achieving automatic loading of the reaction container 2. Simultaneously, when the transfer block 603 moves away from the outlet 602, the sliding block 707, under the reset action of the reset member, causes the blocking surface 702 to block again at the outlet 602, preventing the next reaction container 2 from falling.

[0102] In the sample analysis device 1, after the reaction container 2 falls onto the transport vehicle 101, the transport vehicle 101 moves the reaction container 2 from the feeding position to the sample function position. After the transport vehicle 101 has moved a distance H, the second transport vehicle 101 is positioned at the feeding position and continues to receive the reaction container 2. At the same time, the first transport vehicle 101 moves to the liquid filling position 105. When the second transport vehicle 101 receives the new reaction container 2, the sample and / or reagents are added to the reaction container 2 in the first transport vehicle 101 located at the liquid filling position 105.

[0103] Then, the transport vehicle 101 continues to move a distance H, at which point the first transport vehicle 101 moves to the buffer position 106. The second transport vehicle 101 moves to the liquid filling position 105, and the third transport vehicle 101 moves to the feed position. While the third transport vehicle 101 loads a new reaction vessel 2, samples and / or reagents are added to the reaction vessel 2 located in the second transport vehicle 101 at the liquid filling position 105.

[0104] Then, the transport vehicle 101 continues to move a distance H. During this time, the first transport vehicle 101 moves to the mixing position 104, the second transport vehicle 101 moves to the buffer position 106, the third transport vehicle 101 moves to the liquid filling position 105, and the fourth transport vehicle 101 moves to the feeding position. While the fourth transport vehicle 101 loads a new reaction vessel 2, samples and / or reagents are added to the reaction vessel 2 in the third transport vehicle 101 located at the liquid filling position 105. When the sample in the first transport vehicle 101 needs to be mixed, the first mixing module 305 located in the mixing zone 301 is used directly to mix the reaction vessel 2 in the first transport vehicle 101. Subsequently, when the sample in the reaction vessel 2 needs to be tested, the reaction vessel 2 is moved from the first transport vehicle 101 to the corresponding testing module.

[0105] In some embodiments of this application, the depth of the groove in the stop 701 is greater than or equal to the height of the two protrusions on the ear of the reaction vessel 2, so that the protrusions can pass smoothly through the receiving cavity 708.

[0106] On the other hand, such as Figure 8 As shown, this application embodiment also provides a reaction vessel feeding mechanism 80, including a feeding channel 601 for transporting the reaction vessel 2. One end of the feeding channel 601 is provided with an outlet 602, through which the reaction vessel 2 can be moved out of the feeding channel 601. The limiting mechanism 70 described above is provided at the outlet 602 and is used to limit the reaction vessel 2 at the outlet 602.

[0107] In some embodiments of this application, such as Figure 9 As shown, the container handling mechanism 90 includes a handling block 603, a handling conveyor belt 901, and a belt connecting part 902 fixed to the handling conveyor belt 901. The handling block 603 is fixed to the belt connecting part 902 so that the handling conveyor belt 901 can drive the handling block 603 to move along the second preset path B. The container handling mechanism 90 also includes a support plate 903. The handling conveyor belt 901 is disposed on the support plate 903. On the side of the support plate 903 away from the handling conveyor belt 901, a slide rail 904 extending along the extension direction of the second preset path B is also provided. The belt connecting part 902 is connected between the slide rail 904 and the handling conveyor belt 901, and the belt connecting part 902 is movably disposed along the slide rail 904. The handling block is movably disposed along the slide rail 904 via the belt connecting part 902.

[0108] Please refer to some embodiments of this application. Figure 2The outlet 602 and the transport vehicle 101 are spaced apart along the third direction Z, while the container handling mechanism 90 and the feeding mechanism 80 are spaced apart along the second direction Y. In the direction from the transport vehicle 101 to the outlet 602, the container handling mechanism 90 is inclined towards the outlet 602 to create clearance space between the container handling mechanism 90 and the feeding mechanism 80 for the transport vehicle 101 to pass through. By providing clearance space, the container handling mechanism 90, the feeding mechanism 80, and the transport vehicle 101 are rationally arranged, improving the loading rate of the reaction container 2.

[0109] Another aspect of this application embodiment also provides a reaction vessel 2 operating device, including a transport component 10, the transport component 10 having a straight transport path, a transport vehicle 101 transporting the reaction vessel 2 along the straight transport path, the straight transport path including a feeding position; as described above, the reaction vessel loading device 60 is set corresponding to the feeding position to realize the automatic loading of the reaction vessel 2.

[0110] like Figure 10 As shown, this application embodiment also provides a method for transferring reaction vessel 2, which is applied to the reaction vessel 2 loading device as described above, including the following steps:

[0111] Step S01: Move the transport block 603 of the drive container transport mechanism 90 to the receiving position 604, push the reaction container 2 in the feed channel 601 to move towards the receiving position 604, so that the reaction container 2 located at the outlet 602 enters the transport block 603.

[0112] Step S02: Drive the transport block 603 along a preset path, and move the reaction container 2 to the transport vehicle 101 at a predetermined position. The preset path is, for example, the second preset path B mentioned above.

[0113] Step S03: Drive the transport block 603 to continue moving along the preset path, so that the reaction container 2 slides out of the transport block 603 along the direction restricted by the transport vehicle 101 and falls into the transport vehicle 101 located at the predetermined position.

[0114] In the method for transferring the reaction vessel 2 provided in this application, step S01 allows the reaction vessel 2 located at the outlet 602 to enter the transfer block 603. Then, step S02 moves the reaction vessel 2, causing the bottom of the reaction vessel 2 suspended from the transfer block 603 to enter the transport vehicle 101. Finally, step S03 causes the transport vehicle 101 to continue moving, and the reaction vessel 2, which is limited by the wall of the transport vehicle 101, slides out of the transfer block 603 and falls into the transport vehicle 101 located at a predetermined position. Therefore, the method provided in this application can achieve automatic loading of the reaction vessel 2 and improve the transfer efficiency of the reaction vessel 2.

[0115] like Figure 11As shown, in some embodiments of this application, this application also provides a method for scheduling a reaction vessel 2, using the sample analysis device 1 as described above, and the transport vehicle 101 including a first transport vehicle and a second transport vehicle, the method including:

[0116] Step S1: Control the transport component 10 to transport the first transport vehicle to the feeding position while simultaneously transporting the second transport vehicle to the sample function position.

[0117] Step S2: Load the new reaction container 2 into the first transport vehicle. At the same time, if there is a reaction container 2 in the second transport vehicle of the sample function position, perform a predetermined operation on the reaction container 2 in the second transport vehicle of the sample function position.

[0118] In this application, step S1 enables simultaneous transport by the first and second transport vehicles, improving the flow efficiency of the reaction vessel 2. Then, step S2 allows for simultaneous operation of the reaction vessel 2 within both the first and second transport vehicles, further enhancing sample analysis efficiency.

[0119] like Figure 12 As shown, in some embodiments of this application, another method for scheduling the reaction vessel 2 is also provided, using the sample analysis device 1 as described above. The transport vehicle 101 further includes a first transport vehicle, a second transport vehicle, and a third transport vehicle. The sample function positions include a liquid filling position 105 and a mixing position 104. The method includes:

[0120] Step S3: Control the transport component 10 to transport the first transport vehicle to the feeding position, while simultaneously transporting the second transport vehicle to the liquid filling position 105 and the third transport vehicle to the mixing position 104.

[0121] Step S4: Load a new reaction container 2 into the first transport vehicle. If there is a reaction container 2 in the second transport vehicle at the liquid filling position 105, perform the operation of adding a predetermined liquid to the reaction container 2 in the second transport vehicle at the liquid filling position. If there is a reaction container 2 in the third transport vehicle at the mixing position 104, perform the mixing operation on the reaction container 2 in the third transport vehicle at the mixing position 104.

[0122] In this application, step S3 enables simultaneous transport of the first, second, and third transport vehicles, improving the flow efficiency of the reaction vessel 2. Then, step S4 allows for simultaneous operation of the reaction vessel 2 within the first, second, and third transport vehicles, further enhancing sample analysis efficiency.

[0123] like Figure 13As shown, in some embodiments of this application, another method for scheduling the reaction vessel 2 is also provided. Using the sample analysis device 1 as described above, the transport vehicle 101 further includes a first transport vehicle, a second transport vehicle, a third transport vehicle, and a fourth transport vehicle. The sample function positions include a liquid filling position 105, a buffer position 106, and a mixing position 104 spaced apart. The method includes:

[0124] Step S5: Control the transport component 10 to transport the first transport vehicle to the feeding position, while simultaneously transporting the second transport vehicle to the liquid filling position 105, the third transport vehicle to the buffer position 106, and the fourth transport vehicle to the mixing position 104.

[0125] Step S6: Load a new reaction container 2 into the first transport vehicle. If there is a reaction container 2 in the second transport vehicle at the liquid filling position 105, perform a predetermined liquid filling operation on the reaction container 2 in the second transport vehicle at the liquid filling position 105. If there is a reaction container 2 in the fourth transport vehicle at the mixing position 104, perform a mixing operation on the reaction container 2 in the fourth transport vehicle at the mixing position 104.

[0126] In this application, step S3 enables simultaneous transport of the first, second, third, and fourth transport vehicles, improving the flow efficiency of the reaction vessel 2. Then, step S4 allows for simultaneous operation of the reaction vessel 2 within the first, second, third, and fourth transport vehicles, further improving sample analysis efficiency.

[0127] In any of the above-described reaction vessel 2 scheduling methods, optionally, if there is a reaction vessel 2 in the transport vehicle 101 of the mixing position 104, a mixing operation is performed on the reaction vessel 2 of the mixing position 104 based on a mixing command. If the host computer determines that the sample in the reaction vessel 2 in the transport vehicle 101 of the mixing position 104 needs to be mixed, it sends a command to the first mixing module to perform a mixing action to mix the reaction vessel; if the host computer determines that the sample in the reaction vessel 2 in the transport vehicle 101 of the mixing position 104 does not need to be mixed, it sends a command to the gripper module (not shown in the figure) to grab the reaction vessel to the next station, and the gripper module grabs the reaction vessel 2 from the mixing position 104 to the next station (e.g., the incubation position) according to the command.

[0128] The embodiments described above are not exhaustive, nor do they limit the application to the specific embodiments described herein. Clearly, many modifications and variations can be made based on the above description. These embodiments are selected and specifically described in this specification to better explain the principles and practical applications of this application, thereby enabling those skilled in the art to effectively utilize this application and its modifications. This application is limited only by the claims and their full scope and equivalents.

Claims

1. A sample analysis device, characterized in that, include: A transport assembly includes a transport vehicle that moves along a first preset path. A first position and a second position are spaced apart along the first preset path. The first position is a feed position for loading reaction vessels into the transport vehicle, and the second position is a sample function position for performing predetermined operations on the reaction vessels in the transport vehicle. The transport assembly can simultaneously transport different transport vehicles to the first position and the second position, respectively. The sample analysis device includes a container loading area, which is correspondingly disposed with respect to the first position. The container loading area is provided with a container loading device, which includes: A container feed channel for conveying new reaction vessels is provided on the upper side of the transport assembly. One end of the container feed channel has an outlet, through which the reaction vessel can be moved out of the container feed channel. The transport block, which cooperates with the outlet and is used to receive new reaction containers from the outlet, can move along a second preset path to transport the new reaction containers to the transport vehicle located at the feed position. The transport block can move to the receiving position to dock with the outlet to receive the reaction containers from the outlet. After receiving the reaction containers, the transport block can move along the second preset path and cause the reaction containers to slide out of the transport block and fall into the transport vehicle.

2. The sample analysis device according to claim 1, characterized in that, The first preset path is a straight transportation path extending along a first direction.

3. The sample analysis device according to claim 1 or 2, characterized in that, The sample analysis device also includes a sample functional area, which is correspondingly set with the second position.

4. The sample analysis device according to claim 3, characterized in that, The sample functional area includes a mixing area, and the sample functional position includes a mixing position. The mixing position and the mixing area are correspondingly set. The predetermined operation includes performing a mixing operation on the reaction vessel of the transport vehicle located at the mixing position.

5. The sample analysis device according to claim 4, characterized in that, The sample functional area also includes a reaction liquid storage area, and the sample functional position includes a liquid filling position. The liquid filling position and the reaction liquid storage area are correspondingly set. The predetermined operation includes injecting a predetermined liquid into the reaction container of the transport vehicle located at the liquid filling position. The reaction solution storage area includes a sample rack area and a functional solution area arranged side by side along the second direction. The sample rack area is used to load the sample rack, and the functional solution area is used to store the functional solution. The number of transport vehicles is at least three, and the transport assembly can simultaneously transport different transport vehicles to the mixing position, the liquid filling position and the feeding position respectively. The mixing position, the liquid filling position, and the feed position are arranged sequentially along the first direction.

6. The sample analysis device according to claim 5, characterized in that, The sample function position also includes a buffer position, which is located between the liquid filling position and the mixing position.

7. The sample analysis device according to claim 6, characterized in that, The distance H1 between the feed position and the liquid filling position, the distance H2 between the liquid filling position and the buffer position, and the distance H3 between the buffer position and the mixing position satisfy the relationship H1=H2=H3; The transport component also includes a first conveyor belt for driving the transport vehicle along the first preset path, and a plurality of the transport vehicles are arranged on the first conveyor belt, wherein the distance H between two adjacent transport vehicles satisfies the relationship H=H1=H2=H3; It also includes a control mechanism for controlling the first conveyor belt to transport the transport vehicle along the first preset path; The control mechanism includes a controller, a first photoelectric sensor located at the feeding position, a second photoelectric sensor located at the liquid dispensing position, a third photoelectric sensor located at the mixing position, and a first drive device for driving the first conveyor belt to move. The controller is electrically connected to the first photoelectric sensor, the second photoelectric sensor, the third photoelectric sensor, and the first drive device, respectively, to control the first drive device to drive the movement of the first conveyor belt according to the sensing signals of the first photoelectric sensor, the second photoelectric sensor, and the third photoelectric sensor.

8. The sample analysis device according to claim 7, characterized in that, The mixing zone includes a first mixing module for mixing a predetermined liquid in a reaction vessel located in the mixing position within the transport vehicle. The reaction vessel contains magnetic beads, and the first mixing module has a magnetic component that can move along a third preset path. The magnetic component moves along the third preset path to drive the magnetic beads to move within the reaction vessel, thereby mixing the liquid within the reaction vessel.

9. The sample analysis device according to claim 8, characterized in that, It also includes a detection zone, which and the mixing zone are located on opposite sides of the transport assembly in the second direction, and the detection zone and the reaction liquid storage zone are located on the same side of the transport assembly. The detection zone includes a detection module, which is used to detect the characteristics of the sample in the reaction vessel. The detection module includes a magnetic bead detection module and an optical detection module arranged side by side along the second direction, with the magnetic bead detection module located on the side of the optical detection module facing the first mixing module.

10. The sample analysis device according to claim 9, characterized in that, The detection area also includes an incubation module arranged side by side with the first mixing module and the detection module along the second direction, and the incubation module is located on the side of the detection module facing the first mixing module; The detection area further includes a second mixing module, which is located between the incubation module and the detection module.

11. The sample analysis device according to claim 9, characterized in that, It also includes a reagent area for storing reagents that react with the sample, the reagent area being located between the detection area and the reaction solution storage area; The reagent area includes a first reagent area and a second reagent area arranged side by side along a first direction.

12. A method for scheduling reaction vessels, characterized in that, Using the sample analysis equipment as described in claim 1, the transport vehicle includes a first transport vehicle and a second transport vehicle, and the method includes... The transport component is controlled to transport the first transport vehicle to the first location while simultaneously transporting the second transport vehicle to the second location. A new reaction vessel was loaded into the first transport vehicle, and at the same time If there is a reaction vessel in the second transport vehicle of the sample function position, perform a predetermined operation on the reaction vessel in the second transport vehicle of the sample function position.

13. The reaction vessel scheduling method according to claim 12, characterized in that, The second position includes a mixing position, in which, if there is a reaction vessel in the transport vehicle at the mixing position, a mixing operation is performed on the reaction vessel at the mixing position based on a mixing command.

14. A method for scheduling reaction vessels, characterized in that, Using the sample analysis device as described in claim 1, the transport vehicle further includes a first transport vehicle, a second transport vehicle, and a third transport vehicle, the second location includes a liquid filling position and a mixing position, and the method includes... The system controls the transport assembly to simultaneously transport the first transport vehicle to the first position, the second transport vehicle to the liquid filling position, and the third transport vehicle to the mixing position. A new reaction vessel was loaded into the first transport vehicle, and at the same time If there is a reaction vessel in the second transport vehicle at the liquid filling position, the operation of filling the reaction vessel in the second transport vehicle at the liquid filling position with the predetermined liquid is performed. If there is a reaction vessel in the third transport vehicle at the mixing position, the operation of mixing the reaction vessel in the third transport vehicle at the mixing position is performed.

15. A method for scheduling reaction vessels, characterized in that, Using the sample analysis device as described in claim 1, the transport vehicle further includes a first transport vehicle, a second transport vehicle, a third transport vehicle, and a fourth transport vehicle; the second position includes a liquid filling position, a buffer position, and a mixing position arranged at intervals; the method includes... The transport assembly is controlled to transport the first transport vehicle to the first position while simultaneously transporting the second transport vehicle to the liquid filling position, the third transport vehicle to the buffer position, and the fourth transport vehicle to the mixing position. A new reaction vessel was loaded into the first transport vehicle, and at the same time If there is a reaction vessel in the second transport vehicle at the liquid filling position, a predetermined liquid filling operation is performed on the reaction vessel in the second transport vehicle at the liquid filling position; if there is a reaction vessel in the fourth transport vehicle at the mixing position, a mixing operation is performed on the reaction vessel in the fourth transport vehicle at the mixing position.

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