A filter device for virus removal filtration of a protein-containing feed liquid and a method of virus removal filtration of a protein-containing feed liquid

By combining a multi-layered filtration unit structure with a high-efficiency virus-removing membrane, the problems of easy damage and complex operation of cartridge filters are solved, achieving a highly efficient and convenient virus filtration effect.

CN116440580BActive Publication Date: 2026-07-24HANGZHOU COBETTER FILTRATION EQUIPMENT CO LTD
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Patent Information

Application Number
CN202310093223.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2022-01-14
Filing Date
2023-01-12
Publication Date
2026-07-24
Estimated Expiration
2043-01-12

AI Technical Summary

Technical Problem

Existing cartridge filters are easily damaged during the virus removal process, resulting in poor filtration performance and complicated operation.

Method used

It adopts a multi-layer filtration unit structure, including a filtrate guiding screen, a filter layer and an encapsulation layer. It uses a high-efficiency virus removal membrane (LRV not less than 4, protein yield not less than 98%), and enhances the sealing performance through the inlet guiding screen and adhesive to ensure filtration uniformity and stability.

Benefits of technology

It achieves highly efficient virus removal, simplifies operation, improves the service life and filtration efficiency of the filter device, and reduces time and cost.

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Abstract

The application discloses a filtering device for virus removal filtration of a protein-containing feed liquid and a method for virus removal filtration of a protein-containing feed liquid, and relates to the technical field of biological filtration. The filtering device comprises a filtering unit, a packaging layer, a liquid inlet channel, a filtrate channel and a filtering layer, wherein the filtering layer comprises a virus removal membrane, the LRV of the virus removal membrane for virus impurities is not less than 4, and the protein yield is not less than 98%, the virus removal membrane comprises a pre-filtering layer and a separation layer for intercepting viruses and having a pore size smaller than that of the pre-filtering layer, and at least one pre-filtering layer is arranged on the surface of the side of the virus removal membrane away from the filtrate guide screen. The filtering device has the advantages of simple structure, convenient operation, good virus removal effect of the virus removal membrane on the protein-containing feed liquid, and the like.
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