Boron neutron capture therapy system and method for selecting irradiation parameters thereof

By establishing a three-dimensional voxel prosthetic tissue model based on non-radioactive and radionuclide medical images, and combining it with Monte Carlo simulation, the boron concentration data was accurately given, which solved the problem of inaccurate boron concentration information acquisition in boron neutron capture therapy, and improved the accuracy of dose calculation and treatment effect.

CN116603176BActive Publication Date: 2026-07-10NEUBORON THERAPY SYST LTD
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
NEUBORON THERAPY SYST LTD
Filing Date
2020-10-14
Publication Date
2026-07-10

AI Technical Summary

Technical Problem

In existing boron neutron capture therapy systems, the methods for obtaining boron concentration information fail to consider the actual distribution and metabolism of boron drugs in the body, resulting in insufficient reliability of dosage calculation results and affecting treatment efficacy.

Method used

Using a neutron beam irradiation device, a treatment planning module, and a control module, a three-dimensional voxel prosthetic tissue model is established using non-radioactive and radionuclide medical imaging data. Combined with a Monte Carlo simulation program, boron concentration data is precisely given and dose simulation calculations are performed to generate a treatment plan.

Benefits of technology

It improves the accuracy of model establishment and dose calculation, ensuring that the treatment plan is more in line with the actual situation, reducing radiation damage to normal tissues, and improving the efficiency of tumor cell killing.

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Abstract

A boron neutron capture therapy system and a treatment planning generation method thereof, the boron neutron capture therapy system comprising a neutron beam irradiation device, a treatment planning module and a control module. The neutron beam irradiation device is used to generate a therapeutic neutron beam and irradiate to a boron-containing drug-incorporated irradiated body to form an irradiated site during irradiation therapy. 10 B). The treatment planning module performs dose simulation calculation according to medical image data of the irradiated site and parameters of the therapeutic neutron beam generated by the neutron beam irradiation device, and generates a treatment plan, wherein the medical image data of the irradiated site comprises tissue-related information and boron 10 B) concentration-related information. The control module calls the treatment plan corresponding to the irradiated body from the treatment planning module, and controls the neutron beam irradiation device to perform irradiation therapy on the irradiated body according to the treatment plan. The boron neutron capture therapy system and the treatment planning generation method thereof can improve the accuracy of model establishment and dose calculation.
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