A herbicidal composition comprising mesosulfuron and its use

Abstract

The present application belongs to the field of pesticides, and particularly relates to a herbicidal composition containing mesosulfuron-methyl and application thereof. The herbicidal composition comprises a herbicidally effective amount of active ingredient A and active ingredient B, wherein the active ingredient A is mesosulfuron-methyl, and the active ingredient B is selected from one or two of the following compounds: prometon or simazine. The composition can effectively prevent and control the problems of Alopecurus aequalis, Beckmannia, Galium aparine, Galium spurium, and Veronica, and has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce a synergistic effect, and solving the problem of resistant weeds.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of pesticides, and particularly relates to a herbicidal composition containing mesosulfuron and application thereof. BACKGROUND

[0002] Chemical weeding is the most economical and effective means in the prevention and control of weeds in farmland, but long-term continuous high-dose use of single variety or single action mode of chemical herbicides can easily cause weed tolerance and resistance evolution and other problems.

[0003] Mesosulfuron belongs to the sulfonylurea class of highly effective herbicides, and acts by inhibiting acetolactate synthase, and is absorbed by weeds roots and leaves, conducted in the plant body, so that the weeds stop growing and then die.

[0004] Reasonable compounding or mixing of herbicide compounds has the advantages of expanding the weed spectrum, improving the prevention and control effect, delaying the occurrence and development of weed tolerance and resistance, and the like, and is one of the most effective methods for solving the above problems, and it is still necessary to develop herbicidal composition varieties with high safety, wide weed spectrum, synergistic effect and resistance to resistant weeds. SUMMARY

[0005] To solve the above problems in the prior art, the present application provides a herbicidal composition containing mesosulfuron and application thereof. The composition can effectively prevent and control weeds such as loose smut, Chinese sprangletop, goosegrass, pigweed, and cornflower, has the characteristics of expanding the weed spectrum, reducing the application amount, producing synergistic effect, and solving resistant weeds.

[0006] A herbicidal composition containing mesosulfuron, comprising a herbicidal effective amount of active ingredient A and active ingredient B, wherein the active ingredient A is mesosulfuron (CAS: 208465-21-8), and the active ingredient B is selected from one or two of the following compounds: prometon (CAS: 7287-19-6) or simazine (CAS: 1014-70-6).

[0007] The weight ratio of A and B in the herbicidal composition is 1:100-30:1, preferably 1:80-10:1, more preferably 1:50-1:1, and further preferably 1:40-2:5.

[0008] The mass percentage of A and B in the herbicidal composition accounts for 1-95% of the total amount, preferably 10-80%.

[0009] The herbicidal composition further comprises conventional adjuvants, and the conventional adjuvants include carriers and / or surfactants.

[0010] The term "carriers" in the present text means an organic or inorganic, natural or synthetic substance. They contribute to the application of the active ingredients, the carriers are generally inert and must be agriculturally acceptable, in particular by the plants treated. The carriers can be solid, such as clays, natural or synthetic silicates, silicas, resins, waxes, solid fertilizers, etc. or liquid, such as water, alcohols, ketones, petroleum fractions, aromatic or waxy hydrocarbons, chlorinated hydrocarbons, liquefied gases, etc.

[0011] The surfactants can include emulsifiers, dispersants or wetting agents, which can be ionic or non-ionic. Examples that can be mentioned are salts of polyacrylic acid, lignosulfonates, salts of phenol sulfonic or naphthalene sulfonic acid, polymers of ethylene oxide with aliphatic alcohols or with aliphatic acids or with aliphatic amines and substituted phenols, in particular alkylphenols or arylphenols, sulfosuccinates, taurine derivatives, in particular taurine alkyl esters, and phosphoric esters of alcohols or of polyhydroxyethylated phenols, alkylsulfonates, alkylarylsulfonates, alkylsulfates, lauryl ether sulfates, fatty alcohol sulfates, and sulfated hexa-, hepta- and octadecanols and sulfated fatty alcohol glycol ethers, in addition to condensates of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ethers, ethoxylated isooctylphenol, octylphenol or nonylphenol, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol / ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether formal, sorbitol esters, lignosulfite waste liquors, and proteins, denatured proteins, polysaccharides (e.g. methylcellulose), hydrophobically modified starches, polyvinyl alcohol, polycarboxylates, polyalkoxylates, polyvinylamines, polyvinylpyrrolidone and copolymers thereof. At least one surfactant is required to facilitate the dispersion of the active ingredients in water and to enable their correct application to the plants.

[0012] The above compositions can also contain various other components, such as protective colloids, adhesives, thickeners, thixotropic agents, penetrants, stabilizers, sequestering agents, dyes, colorings and polymers.

[0013] The herbicidal compositions further comprise at least one safener, preferably one or more of dichlobenil (CAS: 163520-33-0), cyprosulfamide (CAS: 221667-31-8), metrafenone (CAS: 135590-91-9), cloquintocet (CAS: 99607-70-2), gibberellic acid (CAS: 7-06-5), furilazole (CAS: 121776-33-8), metcamifen (CAS: 129531-12-0).

[0014] The composition of the present application can be diluted by the user before use or used directly. It can be prepared by the usual processing methods, i.e. by mixing the active substance with a liquid solvent or solid carrier and, if desired, one or more surfactants such as dispersants, stabilizers, wetting agents, binders, antifoams and the like.

[0015] Specific formulations of the herbicidal composition are dispersible oil suspensions, aqueous suspensions, suspoemulsions, wettable powders, emulsifiable concentrates, water-dispersible granules (dry flowables), emulsions, microemulsions.

[0016] In short, the composition of the present application can be mixed with solid and liquid additives conventionally used in the formulations of the prior art. The amount of active ingredient used varies with the external conditions, such as temperature, humidity, nature of the herbicide used, etc. It can vary greatly, for example between 0.001 and 2.0 kg / ha, or more of active substance, but preferably between 0.1 and 1 kg / ha, in particular between 1 and 500 g / ha.

[0017] In the context of the present specification, if an abbreviation of the common name of an active compound is used, this includes in each case all conventional derivatives, such as esters and salts, and isomers, in particular optical isomers, in particular one or more of the commercially available forms. If the common name denotes an ester or salt, this also includes in each case all other conventional derivatives, such as further esters and salts, free acids and neutral compounds, and isomers, in particular optical isomers, in particular one or more of the commercially available forms. The chemical name of a compound given denotes at least one compound encompassed by the common name, usually the preferred compound. In the case of sulfonamides, such as sulfonylureas, the salts also include salts formed by exchange of the hydrogen atom in the sulfonamide group for a cation. For example, 2-methyl-4-chloro derivatives include, but are not limited to: 2-methyl-4-chloro sodium salt, potassium salt, dimethylammonium salt, isopropylamine salt, and the like, as well as 2-methyl-4-chloro methyl ester, ethyl ester, isooctyl ester, ethylthio ester, and the like; 2,4-D derivatives include, but are not limited to: 2,4-D salts such as sodium salt, potassium salt, dimethylammonium salt, triethanolammonium salt, isopropylamine salt, choline, and the like, as well as 2,4-D esters such as methyl ester, ethyl ester, butyl ester, isooctyl ester, and the like.

[0018] The present application also provides the use of the herbicidal composition for controlling weeds; and a method for controlling the growth of unwanted plants, which comprises applying the herbicidal composition to the plants, plant parts, plant seeds, or areas where the plants grow.

[0019] In addition, the composition of the present application can be applied to the leaves of the plants to be treated, i.e. to the weeds, in particular to the surface affected by the weed infestation or susceptible to infestation, by the method of spraying.

[0020] When the herbicidal composition of the present application is applied, an unexpected synergistic effect is obtained, and the herbicidal activity is more remarkable than the expected sum of the activities of the individual herbicides, and the activities of the individual herbicides. The synergistic effect is manifested in reduced application rates, a wider spectrum of weed control, more rapid and persistent herbicidal action, which are desirable in weed control practice. In terms of the described properties, the new compositions are clearly superior to existing herbicides, achieving reduced use, and are more environmentally friendly.

[0021] The synergistic herbicidal composition of the present application also has the following advantages:

[0022] (1) The composition of the present application is environmentally friendly and readily degradable in the environment.

[0023] (2) The herbicidal composition of the present application is low in cost and easy to use, and has great economic and social benefits in popularization and application.

[0024] All patents, patent applications, and publications mentioned herein are hereby incorporated by reference in their entireties for all purposes. DETAILED DESCRIPTION

[0025] The following examples are not intended to limit the present application, but merely serve to illustrate how the present application is implemented. For some weeds, these examples show particularly remarkable effectiveness. Examples are as follows:

[0026] A) Examples

[0027] 1. Mesotrione + prometryn (1 + 10) dispersible oil suspension

[0028] 1% mesotrione + 10% prometryn + 5% calcium dodecylbenzenesulfonate + 8% cashew phenol polyoxyethylene ether + 3% fatty alcohol polyoxyethylene ether + 2.5% organic bentonite + 2% fumed white carbon + 8% 100# solvent oil + methyl oleate supplement

[0029] 2. Mesotrione + simetryn (1 + 10) dispersible oil suspension

[0030] 1% mesotrione + 10% simetryn + 5% calcium dodecylbenzenesulfonate + 10% sorbitan fatty acid ester polyoxyethylene ether + 3% castor oil polyoxyethylene ether + 2% cashew phenol polyoxyethylene ether + 3% organic bentonite + 3% fumed white carbon + 6% 100# solvent oil + 15% dimethyl naphthalene acid + methyl oleate supplement

[0031] The dispersible oil suspension processing equipment: mixing kettle, colloid mill, sand mill, shear machine, etc.

[0032] The dispersible oil suspension processing procedure is as follows: all materials are put into a mixing kettle, stirred and mixed, then passed through a colloid mill, followed by three-stage sand milling in a sand mill, and finally sheared uniformly in a shearing machine. After passing the test, it is transferred to a storage tank for filling.

[0033] B) Pharmacodynamic test

[0034] Post-emergence stem and leaf spraying treatment:

[0035] 1) Test conditions

[0036] 1.1) Test target

[0037] The weeds are cultivated by using a potting method, using 180x140mm plastic nutrient pots, which are placed in enamel trays, and filled with surface soil (4 / 5) that is collected from farmland, dried and sieved. The soil humidity is initially controlled at 20%, the weed seeds with full and uniform grains are selected, soaked in 25°C water for 6 hours, and then germinated in a 28°C biochemical incubator (darkness). The just-germinated weed seeds are uniformly placed on the soil surface, and then covered with 0.5-1cm soil according to the seed size.

[0038] 1.2) Cultivation conditions

[0039] The test is carried out in a controllable sunlight greenhouse, with a temperature of 20-30°C, natural light, and a relative humidity of 57%-72%. The soil type is loam, with an organic matter content of 1.63%, a pH of 7.1, an alkali-hydrolyzable nitrogen content of 84.3mg / kg, an available phosphorus content of 38.5mg / kg, and an available potassium content of 82.1mg / kg.

[0040] 1.3) Instrument and equipment

[0041] 3WP-2000 type walking spray tower (Nanjing Agricultural Machinery Institute of the Ministry of Agriculture); GA0 type one-millionth electronic balance (Germany); ZDR2000 intelligent data recorder (Hangzhou Zeda Instrument Co., Ltd.); SPX type intelligent biochemical incubator (Ningbo Jiangnan Instrument Factory).

[0042] 2) Test design

[0043] 2.1) Reagent

[0044] The required active ingredients are purchased from a reagent company or synthesized according to a conventional method. The technical material uses acetone as a solvent, which is diluted with a 0.1% emulsifier Tween-80 aqueous solution, and is diluted on demand.

[0045] 2.2) Test treatment

[0046] 2.2.1) Dose setting

[0047] The ratio or content of active ingredient A to active ingredient B should be determined by the characteristics and toxicity of the two agents, and the main purpose of the formulation. Based on the preliminary test, the use amount of A and B active ingredients is shown in the table. The water containing no agent, same solvent and emulsifier was used as a blank control.

[0048] 2.2.2) Test repetition

[0049] Each treatment was repeated 4 times, with 3 pots per treatment, and 20 seeds of weeds were sown in each pot, totaling 60 plants per treatment.

[0050] 2.3) Treatment method

[0051] 2.3.1) Treatment time and frequency

[0052] The test was conducted once with the agent. After the weeds reached 1.5-2 leaves, the seedlings were thinned to maintain 10 plants per pot, and 30 plants per treatment were reserved, and then the cultivation was continued to 2-3 branches for treatment.

[0053] 2.3.2) Use of equipment and method of application

[0054] The well-cultivated test materials were evenly placed on a platform with an area of 0.5 m 2 The stem and leaf spraying was performed using a 3WP-2000 type walking spray tower, with a liquid amount of 450 kg / ha, and a spraying pressure of 0.3 MPa. After all the liquid was sprayed, the valve was closed, and after 30 seconds, the spray tower door was opened, and the nutrient pots were removed. Then the valve was opened, and 50 mL of water was sprayed to clean the spray pipe.

[0055] 3) Test method

[0056] Pot culture method was used. The weed cultivation was as described in 1.1), and the test was conducted according to the "Guidelines for Indoor Biological Determination of Pesticides". The method of application was as described in 2.3.2), and the stem and leaf treatment method was used. After treatment, the pots were moved to the greenhouse for regular cultivation.

[0057] 4) Data investigation and statistical analysis

[0058] 4.1) Investigation method

[0059] The absolute number investigation method was used, and the surviving weed seedlings were cut off along the soil surface with a blade, and the fresh weight of the weeds was weighed with an analytical balance. For the dead weeds, the fresh weight was taken as zero.

[0060] 4.2) Investigation time and frequency

[0061] The investigation was conducted 21 days after treatment, and a total of 1 time.

[0062] 4.3) Data statistical analysis

[0063] The theoretical fresh weight inhibition rate (E0 = X + Y - X*Y / 100) of each treatment mixture combination is calculated by Gowing method, and then compared with the measured inhibition rate (E) to evaluate the joint action type of the two mixtures on weeds, when the value of E-E0 is greater than 10% for synergistic effect, less than -10% for antagonistic effect, and between -10% and 10% for additive effect. The best ratio is determined according to the actual control effect, herbicide characteristics, and formula balance, etc. In the formula, X is the fresh weight inhibition rate of active ingredient A when the dosage is P; Y is the fresh weight inhibition rate of active ingredient B when the dosage is Q.

[0064] The statistical results are shown in Tables 1-2 below.

[0065] Table 1 Actual control effect and joint action evaluation of mesosulfuron-methyl mixed with prometryn on goosegrass

[0066]

[0067]

[0068] Table 2 Actual control effect and joint action evaluation of mesosulfuron-methyl mixed with simetryn on goosegrass

[0069]

[0070] C) Field demonstration

[0071] The herbicidal compositions prepared in Examples 1-2 above are used for effect test in rape fields resistant to ALS and PSII inhibitors, and the main weeds occurring in the fields are: Alopecurus aequalis, Beckmannia syzigachne, goosegrass, Galium aparine, and Veronica spp.

[0072] Test method:

[0073] Stem-leaf treatment (F): when the grass weeds are at 4-5 leaf stage, use a hand sprayer to uniformly spray the weeds with 30 kg of water per 667 m2. 2

[0074] The specific test agents and dosages are shown in Table 3, and the plot area is 20 m2, with 3 repetitions for each treatment. The control effect is investigated 20 days after application, as shown in Table 3.

[0075]

[0076] Field demonstration effect of the compound compositions described in Table 3

[0077]

[0078] ​Through a large number of experiments and explorations, the application surprisingly finds that the composition is used for preventing and treating main gramineae and broadleaf weeds in rape fields against ALS and PSII inhibitor herbicides, has a surprising and unexpected synergistic effect, the synergistic effect is more significant at a low dosage, the application amount can be reduced, the pollution to the environment is reduced, the reasonable compounding reduces the agricultural cost, and has a good application prospect. Meanwhile, through tests in wheat fields, corn fields, rice fields, peanuts, sugarcane, sorghum, millet, potatoes, soybeans, cotton, vegetables, bluegrass, tall fescue, St. Augustine grass and the like, the composition shows good selectivity and excellent synergistic effect, and can be developed into a herbicide mixture with wide market value.

Claims

1. A herbicidal composition comprising mesosulfuron, characterized in that, The herbicidal composition comprises a herbicidally effective amount of active ingredient A and active ingredient B, wherein active ingredient A is mesosulfuron and active ingredient B is selected from one of the following compounds: prometon or simazine; The weight ratio of A and B in the herbicidal composition is 1:50 to 1:

1.

2. The herbicidal composition according to claim 1, characterized by The weight ratio of A and B in the herbicidal composition is 1:40 to 2:

5.

3. The herbicidal composition according to claim 1 or 2, characterized by, The mass percentage of A and B in the herbicidal composition is 1-95% of the total amount.

4. The herbicidal composition according to claim 3, characterized by The mass percentage of A and B in the herbicidal composition is 10-80% of the total amount.

5. The herbicidal composition according to claim 1 or 2, characterized by, The herbicidal composition further comprises conventional adjuvants.

6. The herbicidal composition according to claim 5, characterized by The conventional adjuvants include carriers and / or surfactants.

7. The herbicidal composition according to claim 1 or 2, characterized by, The herbicidal composition further comprises at least one safener.

8. The herbicidal composition according to claim 7, characterized by The safener is selected from one or more of the following: isoxadifen-ethyl, cyprosulfamide, metcamifen, furilazole, cloquintocet, and azafenidin.

9. The herbicidal composition according to claim 1 or 2, characterized by, The specific formulation of the herbicidal composition is dispersible oil suspension, aqueous suspension, suspoemulsion, wettable powder, emulsifiable concentrate, water dispersible granule, emulsion in water, or microemulsion.

10. Use of the herbicidal composition according to any one of claims 1 to 9 for controlling weeds.

11. Use according to claim 10, characterized in that, The herbicidal composition is used for controlling weeds in rape fields that are resistant to ALS and PSII inhibitors.

12. A method for controlling unwanted plant growth, comprising applying the herbicidal composition according to any one of claims 1 to 9 to the plants, plant parts, plant seeds, or areas where the plants grow.

13. The method of claim 12, wherein, The unwanted plants are weeds in rape fields that are resistant to ALS and PSII inhibitors.

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