A traditional Chinese medicine composition for resisting atherosclerosis by regulating immune function and its preparation method

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By regulating the ratio of Th17 and Treg cells with a Chinese herbal composition of red ginseng, zedoary turmeric, red peony root, coptis chinensis and rhizoma dioscoreae, the problem of worsening progression of atherosclerosis was solved, and the stability of immune function and the therapeutic effect without side effects were achieved.

CN117244032BActive Publication Date: 2025-09-26XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI

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Patent Information

Application Number: CN202311380980.8
Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner
Filing Date: 2023-10-24
Publication Date: 2025-09-26
Estimated Expiration: 2043-10-24

Application Information

Patent Timeline

24 Oct 2023

Application

CN202311380980.8

26 Sep 2025

Publication

CN117244032B

IPC: A61K36/9066; A61P37/02; A61P9/10

CPC: A61K36/258; A61K36/9066; A61K36/71; A61K36/65; A61K36/718; A61K36/8945; A61P37/02; A61P9/10

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Application Domain

Immunological disorders Cardiovascular disorder

Technology Topics

Biotechnology Regulatory T cell

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AI Technical Summary

Technical Problem

Existing technologies are difficult to effectively regulate the proportion of T cell subsets, which leads to the aggravation of atherosclerosis progression, and Western medicine treatments have side effects and poor compliance.

Method used

A Chinese herbal medicine combination of red ginseng, zedoary turmeric, red peony root, coptis root and rhizoma dioscoreae is used to regulate the ratio of Th17 and Treg cells and stabilize atherosclerotic plaques by invigorating qi and promoting blood circulation, detoxifying and eliminating symptoms.

Benefits of technology

It significantly improves the body's immune function, stabilizes atherosclerotic plaques, improves prognosis, has no toxic side effects, and is suitable for a wider range of people.

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Abstract

The present invention discloses a Chinese medicine composition for resisting atherosclerosis by regulating immune function and its preparation method, relating to the technical field of traditional Chinese medicine. The composition comprises the following raw materials in parts by weight: 3-9 parts of red ginseng, 6-9 parts of zedoary turmeric, 6-12 parts of red peony root, 2-5 parts of coptis root, and 9-15 parts of rhizoma dioscoreae. The composition can regulate the immune imbalance between regulatory T cells (Treg) and helper T 17 cells (Th17) during disease progression, alleviate the chronic inflammatory response in atherosclerotic plaques, enhance plaque stability, and improve prognosis.

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