Anti-hair loss and anti-itching shampoo containing plant extracts and preparation method thereof

Abstract

The present invention belongs to the field of daily chemical products, and specifically relates to an anti-hair loss and anti-itching shampoo containing plant extracts and a preparation method thereof, comprising the following components: plant extracts, surfactants, moisturizers, conditioners, anti-dandruff and anti-itching agents, ammonium hydroxide, citric acid, preservatives, essences and the remainder of purified water; wherein the plant extracts are composed of ginseng (PANAX GINSENG) root extracts, Alpinia SPECIOSA leaf extracts and Cyperus ESCULENTUS (CYPERUS ESCULENTUS) root oils in a mass ratio of 2-3:2-5:1; the conditioners include deacetylated chitosan, histidine and amino-terminated polydimethylsiloxane; and the anti-dandruff and anti-itching agent is piroctone ethanolamine salt. The anti-hair loss and anti-itching shampoo of the present invention is mild in use, effectively stops itching, has a significant effect on improving hair loss, and has both the dual effects of preventing hair loss and stopping itching.

Description

Technical Field

[0001] The invention belongs to the field of daily chemical products, and particularly relates to an anti-hair loss and anti-itching shampoo containing plant extracts and a preparation method thereof. Background Art

[0002] Hair loss refers to the phenomenon of hair loss. Hair loss can be roughly divided into physiological hair loss and pathological hair loss. Physiological hair loss is because the growth of hair is cyclical, which can be divided into the growth phase, regression phase and resting phase. The hair in the growth phase accounts for about 85% of all hair. During this period, the hair grows 0.27-0.4mm every day. The growth phase of hair is 2-6 years. After entering the regression phase, the hair bulb in the lower part of the hair follicle, including the hair growth part, begins to shrink. The hair no longer grows and becomes loose and easy to fall off; about 1% of the hair is in the regression phase; in the resting phase, the lower part of the hair follicle completely shrinks and the hair falls off, and about 14% of the hair is in the resting phase; the resting phase lasts for 3-6 months, and then the hair follicle enters the growth phase and new hair grows. Physiological hair loss will fall off about 50-75 hairs every day. Pathological hair loss can be divided into the following types from the perspective of etiology: seborrheic alopecia, which often occurs in young and middle-aged people, characterized by thick oily secretions on the scalp, shiny, sparse and thin hair, or dry and dull hair, much dandruff, itchy scalp, sparse and thin hair; pathological hair loss: mainly due to damage to hair matrix cells by viruses, bacteria, and high fever, which inhibits the normal division of hair matrix cells, and puts hair follicles in a state of shock, leading to hair loss, such as acute infectious diseases, long-term use of certain drugs, etc.; chemical hair loss: damage to scalp tissue and hair follicle cells by harmful chemicals, leading to hair loss; physical hair loss: hair loss caused by external force pulling, air pollutants blocking hair follicles, harmful radiation, etc.; nutritional hair loss: malnutrition caused by digestive and absorption dysfunction leads to hair loss; hereditary hair loss: hair loss is also hereditary, generally dominant in males and recessive in females.

[0003] There are many shampoos with anti-hair loss and anti-itching effects in the prior art, and the active components are different and the effects vary. Shampoos with chemical substances as active ingredients are prone to irritation to the scalp and are not suitable for long-term use; shampoos with Chinese medicine or plant extracts as active ingredients are milder, but the effects are not significant and it is difficult to meet the needs.

[0004] CN104546663B discloses an anti-hair loss and hair growth shampoo, which uses Paenibacillus and acetic acid as anti-dandruff and anti-hair loss shampoo and is added to shampoo.

[0005] CN104644515B discloses an anti-hair loss shampoo and conditioner, which adds tea bran, mulberry leaves, vitex rotundifolia, ginger, smilax china, gecko and ligusticum chuanxiong as effective ingredients and has the effects of promoting hair growth and preventing hair loss.

[0006] CN113750014B discloses a hair loss prevention and growth composition, comprising: glycyrrhizin, oleanolic acid, angelica extract and Zanthoxylum bungeanum fruit extract. It can inhibit the activity of 5α-reductase and avoid the problems of rapid entry into the regression phase, miniaturization, hair loss, etc. caused by the high-activity DHT binding to androgen receptors and acting on the hair follicles.

[0007] CN101890080B discloses an anti-hair loss and hair growth shampoo, which adopts a combination of pure natural Chinese medicines such as ginseng, sophora flavescens, polygonum multiflorum, ligusticum chuanxiong and epimedium, and nourishes qi and spleen, replenishes liver and kidney, removes blood stasis and dredges the meridians, so that the blood vessels of the human body are unobstructed, qi and blood are sufficient, and wind evil is eliminated, thereby nourishing the hair and achieving the purpose of preventing hair loss and promoting hair growth.

[0008] Based on this, the present invention provides an anti-hair loss and anti-itching shampoo containing plant extracts and a preparation method thereof, which is not only gentle and effective and can significantly improve hair loss, but can also effectively relieve the itchy symptoms caused by excessive oil secretion on the scalp, thus killing two birds with one stone. Summary of the invention

[0009] The invention provides an anti-hair loss and anti-itching shampoo containing plant extracts, which is mild in use, has a significant anti-hair loss effect, can also significantly improve the symptom of scalp itching, and has the dual effects of anti-hair loss and anti-itching.

[0010] The invention also provides a method for preparing the anti-hair loss and antipruritic shampoo containing the plant extract.

[0011] In a first aspect, the present invention provides an anti-hair loss and antipruritic shampoo containing plant extracts, comprising the following components in percentage by mass: 1-15% plant extract, 5-25% surfactant, 0.1%-5% moisturizer, 0.1%-3% conditioner, 0.1%-0.5% anti-dandruff and antipruritic agent, 0.1%-1% ammonium hydroxide, 0.01%-0.1% citric acid, 0.01%-0.1% preservative, 0%-0.5% essence; and the balance purified water.

[0012] As a preferred embodiment of the present invention, the plant extracts include ginseng root extract, Alpinia speciosa leaf extract and cyperus esculentus root oil.

[0013] As a preferred embodiment of the present invention, the mass ratio of the ginseng root extract, the Alpinia speciosa leaf extract and the cyperus esculentus root oil in the plant extract is 2-3:2-5:1.

[0014] As a preferred embodiment of the present invention, the surfactant is selected from one or a mixture of two or more of sodium cocoyl isethionate, cocamidopropyl betaine, sodium lauroyl glutamate, sodium lauroyl sarcosinate, lauroyl amidopropyl betaine and decyl glucoside.

[0015] As a preferred embodiment of the present invention, the surfactant includes sodium cocoyl isethionate, sodium lauroyl glutamate and decyl glucoside.

[0016] As a preferred embodiment of the present invention, the moisturizing agent is selected from one or a mixture of two or more of propylene glycol, hexylene glycol, glycerol, xylitol, and sodium hyaluronate.

[0017] As a preferred embodiment of the present invention, the moisturizing agent includes hexylene glycol and sodium hyaluronate.

[0018] As a preferred embodiment of the present invention, the conditioning agent is selected from one or a mixture of two or more of glycoprotein, chitosan, panthenol ethyl ether, histidine, and aminopolydimethylsiloxane.

[0019] As a preferred embodiment of the present invention, the conditioning agent includes chitosan, histidine and amino dimethyl siloxane.

[0020] As a preferred embodiment of the present invention, the anti-dandruff and antipruritic agent is piroctone ethanolamine salt.

[0021] As a preferred embodiment of the present invention, the preservative can be selected from any one of benzyl alcohol, sodium benzoate, phenoxyethanol, methylparaben, propylparaben, DMDM ​​hydantoin, or a mixture of two or more thereof.

[0022] As a preferred embodiment of the present invention, the preservative is phenoxyethanol.

[0023] To further describe the preferred embodiment of the present invention, the raw materials of the anti-hair loss and anti-itching shampoo containing plant extracts provided by the present invention are as follows:

[0024] Ginseng root extract can delay skin aging, prevent skin dryness and dehydration, and increase skin elasticity, thereby protecting the skin and preventing and reducing skin wrinkles. Ginseng active substances also have the ability to inhibit the reduction of melanin, making the skin white and smooth. Ginseng in shampoo can dilate the capillaries of the head, increase the nutrition of hair, improve the toughness of hair, reduce hair loss and hair breakage, and protect damaged hair.

[0025] Alpinia speciosa leaf extract is mainly used as a skin conditioner. Its main effect in cosmetics and daily chemical products is anti-aging, which can enhance skin activity, activate skin, and has anti-oxidation and anti-aging effects; it can also promote hair growth and act as a hair promoter; it also has the effects of moisturizing and inhibiting odor.

[0026] Cyperus ESCULENTUS root oil is an essential oil extracted from the root of Cyperus ESCULENTUS. It is rich in vitamin E and linoleic acid, which can prevent skin and hair damage, enhance the barrier function and moisturizing effect of the scalp and skin, enhance its luster and softness, and protect and improve the health of hair and skin.

[0027] Sodium Cocoyl Isethionate (SODIUM COCOYL ISETHIONATE) is used as a cleanser and surfactant in cosmetics. This ingredient is relatively safe, has little irritation to the skin, and has good cleansing ability.

[0028] Sodium lauroyl glutamate (SODIUM LAUROYL GLUTAMATE) is an amino acid surfactant with an amino acid skeleton in the molecule. It is used as a cleanser, antistatic agent, surfactant and emulsifier in cosmetics. It has excellent foaming properties and the mildness unique to acyl amino acid surfactants. It is safe to use and has low irritation to the eyes and skin. It is a very mild skin and hair cleanser, which makes the skin feel soft and moisturized after washing.

[0029] Decyl glucoside (DECYL GLUCOSIDE) is a new type of nonionic surfactant APG, which has the characteristics of common nonionic and anionic surfactants. It has the characteristics of low surface tension, excellent detergency, wetting power and foaming performance.

[0030] Chitosan is a polyhydroxy compound that can bind and retain water through hydrogen bonds and has excellent moisturizing properties, which is almost equivalent to hyaluronic acid. Chitosan has good biocompatibility and biodegradability. As a natural moisturizer, hair conditioner, antioxidant and antibacterial agent, it has broad application prospects in the cosmetics industry.

[0031] Histidine is one of the essential amino acids for the human body and plays an important role in the body. Histidine can be used as a nutritional supplement to enhance the effectiveness of other conditioning agents.

[0032] Amodimethicone is used as a hair conditioning agent and antistatic agent in cosmetics.

[0033] Piroctone ethanolamine (PIROCTONE OLAMINE), also known as anti-dandruff agent OCTO, is a stable, non-toxic and highly effective anti-dandruff and antipruritic agent. It is widely used in anti-dandruff shampoos, hair care lotions, conditioners and other hair care cosmetics. Its anti-dandruff and antipruritic mechanism is through its bactericidal and antioxidant effects, which can eliminate dandruff fundamentally, rather than temporarily eliminating dandruff from the surface through methods such as degreasing. In addition to its excellent anti-dandruff effect, it also has antiseptic, deodorizing and acne-removing effects.

[0034] In a second aspect, the present invention provides a method for preparing an anti-hair loss and antipruritic shampoo containing a plant extract, comprising the following preparation steps:

[0035] 1) Heat the surfactant and conditioner to 70-90°C and stir for 20-60 minutes to mix evenly. Keep warm for 10-20 minutes and then cool to 30-45°C to obtain material A.

[0036] 2) Mix the moisturizer, anti-dandruff and antipruritic agent, ammonium hydroxide, citric acid and purified water, heat to 30-50°C, stir for 20-45 minutes, and mix well to obtain material B;

[0037] 3) Evenly mix the material A obtained in step 1), the material B obtained in step 2), the plant extract, the preservative and the essence to obtain the anti-hair loss and anti-itching shampoo containing the plant extract.

[0038] As a preferred embodiment of the present invention, the plant extracts include ginseng root extract, Alpinia speciosa leaf extract and cyperus esculentus root oil.

[0039] As a preferred embodiment of the present invention, the mass ratio of the ginseng root extract, the Alpinia speciosa leaf extract and the cyperus esculentus root oil in the plant extract is 2-3:2-5:1.

[0040] As a preferred embodiment of the present invention, the surfactant is selected from one or a mixture of two or more of sodium cocoyl isethionate, cocamidopropyl betaine, sodium lauroyl glutamate, sodium lauroyl sarcosinate, lauroyl amidopropyl betaine and decyl glucoside.

[0041] As a preferred embodiment of the present invention, the surfactant includes sodium cocoyl isethionate, sodium lauroyl glutamate and decyl glucoside.

[0042] As a preferred embodiment of the present invention, the moisturizing agent is selected from one or a mixture of two or more of propylene glycol, hexylene glycol, glycerol, xylitol, and sodium hyaluronate.

[0043] As a preferred embodiment of the present invention, the moisturizing agent includes hexylene glycol and sodium hyaluronate.

[0044] As a preferred embodiment of the present invention, the conditioning agent is selected from one or a mixture of two or more of glycoprotein, chitosan, panthenol ethyl ether, histidine, and aminopolydimethylsiloxane.

[0045] As a preferred embodiment of the present invention, the conditioning agent includes chitosan, histidine and amino dimethyl siloxane.

[0046] As a preferred embodiment of the present invention, the anti-dandruff and antipruritic agent is piroctone ethanolamine salt.

[0047] As a preferred embodiment of the present invention, the preservative can be selected from any one of benzyl alcohol, sodium benzoate, phenoxyethanol, methylparaben, propylparaben, DMDM ​​hydantoin, or a mixture of two or more thereof.

[0048] As a preferred embodiment of the present invention, the preservative is phenoxyethanol.

[0049] As a preferred embodiment of the present invention, a method for preparing an anti-hair loss and anti-itching shampoo containing plant extracts comprises the following preparation steps:

[0050] 1) Heat the surfactant and conditioner to 75-85°C and stir for 35-45 minutes to mix evenly. Keep warm for 10-20 minutes and then cool to 35-45°C to obtain material A.

[0051] 2) Mix the moisturizer, anti-dandruff and antipruritic agent, ammonium hydroxide, citric acid and purified water, heat to 35-45°C, stir for 25-35 minutes, and mix well to obtain material B;

[0052] 3) Evenly mix the material A obtained in step 1), the material B obtained in step 2), the plant extract, the preservative and the essence to obtain the anti-hair loss and anti-itching shampoo containing the plant extract.

[0053] As a preferred embodiment of the present invention, the plant extracts include ginseng root extract, Alpinia speciosa leaf extract and cyperus esculentus root oil.

[0054] As a preferred embodiment of the present invention, the mass ratio of the ginseng root extract, the Alpinia speciosa leaf extract and the cyperus esculentus root oil in the plant extract is 1-3:2-5:1.

[0055] As a preferred embodiment of the present invention, the surfactant includes sodium cocoyl isethionate, sodium lauroyl glutamate and decyl glucoside.

[0056] As a preferred embodiment of the present invention, the moisturizing agent includes hexylene glycol and sodium hyaluronate.

[0057] As a preferred embodiment of the present invention, the conditioning agent is selected from chitosan, histidine and amino dimethicone.

[0058] As a preferred embodiment of the present invention, the anti-dandruff and antipruritic agent is piroctone ethanolamine salt.

[0059] As a preferred embodiment of the present invention, the preservative is phenoxyethanol.

[0060] The beneficial technical effects of the present invention are:

[0061] (1) The present invention provides an anti-hair loss and anti-itching shampoo containing plant extracts, which uses plant extracts as anti-hair loss efficacy components and has a mild effect. The plant extracts include ginseng (PANAX GINSENG) root extract, Alpinia SPECIOSA leaf extract and Cyperus ESCULENTUS root oil. The ginseng (PANAX GINSENG) root extract, Alpinia SPECIOSA leaf extract and Cyperus ESCULENTUS root oil in the plant extracts are prepared in a mass ratio of 1-3:2-5:1, which produces a significant anti-hair loss and anti-itching effect.

[0062] (2) The anti-hair loss and anti-itching shampoo of the present invention combines plant extracts with conditioning agents and anti-dandruff and anti-itching agents to achieve synergistic effects, thereby consolidating the dual effects of anti-hair loss and anti-itching. The conditioning agent is composed of deacetylated chitosan, histidine and amino-terminated polydimethylsiloxane, and the anti-dandruff and anti-itching agent is piroctone ethanolamine salt. DETAILED DESCRIPTION

[0063] In order to more fully understand the technical content of the present invention, the present invention will be further introduced and illustrated in conjunction with specific embodiments below; obviously, the embodiments described below are only part of the embodiments of the present invention, rather than all of the embodiments; based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present invention. Example

[0064] Table 1 Examples 1-3 Anti-hair loss and anti-itching shampoo containing plant extracts (wt%) Formula

[0065]

[0066]

[0067] The preparation method of the anti-hair loss and anti-itching shampoo containing plant extracts comprises the following preparation steps:

[0068] 1) Heat sodium cocoyl isethionate, sodium lauroyl glutamate, decyl glucoside, chitosan, histidine and amino dimethicone to 80°C and stir for 40 minutes, mix evenly, keep warm for 15 minutes and then cool to 40°C to obtain material A;

[0069] 2) Mix hexylene glycol, sodium hyaluronate, piroctone olamine salt, ammonium hydroxide, citric acid and purified water, heat to 40°C, stir for 30 minutes, and mix well to obtain material B;

[0070] 3) Evenly mix the material A obtained in step 1), the material B obtained in step 2), ginseng root extract, Alpinia speciosa leaf extract, cyperus esculentus root oil, phenoxyethanol and essence to obtain an anti-hair loss and anti-itching shampoo containing plant extracts.

[0071] Comparative Example 1

[0072] The difference between Comparative Example 1 and Example 1 is that the mass percentage of ginseng (PANAX GINSENG) root extract is adjusted to 1%, the mass percentage of Alpinia speciosa (ALPINIA SPECIOSA) leaf extract is adjusted to 1%, and the mass percentage of cyperus esculentus (CYPERUS esculentus) root oil is adjusted to 6%, and the other parameters are the same as those in Example 1.

[0073] Comparative Example 2

[0074] The difference between Comparative Example 2 and Example 1 is that the ginseng root extract is replaced by an equal amount of Polygonum multiflorum root extract, and the Alpinia peculiar leaf extract is replaced by an equal amount of Platycladus orientalis leaf extract, and the other parameters are the same as those in Example 1.

[0075] Comparative Example 3

[0076] The difference between Comparative Example 3 and Example 1 is that histidine is replaced by an equal amount of purified water, and piroctone olamine salt is replaced by an equal amount of salicylic acid. The other parameters are the same as those in Example 1.

[0077] Experimental Example 1 Antibacterial Test

[0078] When the scalp is healthy, it will secrete an appropriate amount of oil. At this time, Malassezia exists in the form of spores and the number is within the normal range. When the scalp secretes excessive oil, it will promote the reproduction of Malassezia, and the fatty acids it secretes will continue to damage the scalp barrier, leading to itchy scalp, dandruff, oily scalp, hair loss and other problems. It can be seen that excessive Malassezia is one of the root causes of itchy scalp, hair loss and other problems.

[0079] In order to determine the inhibitory effect of the anti-hair loss and antipruritic shampoo containing plant extracts on Malassezia, this experimental example adopts the test method in CN115212144A. The stably cultured Malassezia furfur is prepared in a culture medium with a concentration of 10 6 CFU / mL bacterial suspension, the preparation method of the culture medium is: take 60g agar, 20g dried ox bile, 10g Tween 40, 2.5g glycerol monostearate, dissolve in 1000ml distilled water, 121℃, sterilize for 15min. Use sterile water to prepare the anti-hair loss and anti-itching shampoo containing plant extracts prepared in Examples 1 to 3 and Comparative Examples 1 to 3 into sample solutions with a concentration of 20% (v / v) with purified water. Take 0.5mL of bacterial suspension in a test tube and inject 4.5ml of sample solution. Take 0.5mL of bacterial suspension in a test tube in the control group and inject 4.5ml of purified water. Immediately after mixing, start timing, take 1.0ml of the mixed solution at different action time points, and determine the number of viable bacteria using the live bacteria culture counting method. The measurement results are shown in Table 2.

[0080] Table 2: Inhibition rate of Malassezia furfur at different time points (%)

[0081] 5min 15min 25min Control group - - 0.1 Example 1 70.1 92.4 99.9 Example 2 68.3 91.7 99.8 Example 3 72.5 94.2 99.9 Comparative Example 1 65.4 80.6 93.7 Comparative Example 2 63.1 78.9 88.5 Comparative Example 3 69.0 86.3 95.4

[0082] By comparing the antibacterial rates of Examples 1 to 3 and Comparative Examples 1 to 2, it can be clearly found that the anti-hair loss and antipruritic shampoo containing plant extracts of the present invention has a significant antibacterial effect on Malassezia due to the plant extracts composed of ginseng root extract, Alpinia peciosa leaf extract and Cyperus esculentus root oil in a mass ratio of 1 to 3: 2 to 5: 1. The antibacterial rates of Example 1 and Comparative Example 3 can be clearly found that the compatibility of the plant extract with the conditioner and the anti-dandruff and antipruritic agent in the present invention is also a key combination to ensure the efficacy of the product.

[0083] Experimental Example 2: Mouse hair growth test

[0084] 40 Kunming mice were selected, half of which were male and half were female. The hair on the back was cut short, and 6% Na2S was applied as a depilatory agent to the back skin of the mice. The depilatory area was about 3*3cm 2 , after applying the depilatory agent for about 2 minutes, wipe it clean with warm water. The standard for depilation is that the mouse back is smooth and clean without any injuries or residual hair. The day after depilation, the mice were randomly divided into 4 groups: blank group, sample group, control group 1, and control group 2. The blank group was not given any medication, and the sample group, control group 1, and control group 2 were respectively given 0.1ml / 9cm on the depilatory area. 2 Apply the following composition in doses:

[0085] Sample group: a composition prepared by mixing ginseng root extract, Alpinia speciosa leaf extract and cyperus esculentus root oil in a mass ratio of 2:5:1;

[0086] Control group 1: a composition prepared by mixing Panax ginseng root extract, Alpinia azedarach leaf extract and Cyperus esculentus root oil in a mass ratio of 1:1:6;

[0087] Control group 2: a composition prepared by uniformly mixing the root extract of Polygonum multiflorum, the leaf extract of Platycladus orientalis and the root oil of Cyperus esculentus in a mass ratio of 2:5:1.

[0088] The sample group, control group 1, and control group 2 were smeared with the corresponding composition twice a day at 8 am and 6 pm for 14 consecutive days. The growth of new hair in the hair removal area of ​​each group of mice was scored on the 3rd, 7th, 10th, and 14th days. The scoring criteria are shown in Table 3. The length of new hair in the hair removal area was measured on the second day after 14 days of smearing. The measurement method was to pluck the longest 10 new hairs in the hair removal area with a magnifying glass and tweezers, and measure the length of the new hair with a vernier caliper.

[0089] Table 3 Scoring criteria for new hair growth in mice

[0090] Rating value New hair growth 0 Hairless growth 1 Light hair growing all over the hair removal area 2 The length and density of new hair is about half of the unremoved area. 3 The length of new hair is no different from that of the unremoved area

[0091] Note: The mice with irregular new hair growth were calculated based on the area ratio.

[0092] Table 4 Scoring results of new hair growth in the hair removal area of ​​each group of mice (x̄±s, n=10)

[0093] Group Day 3 Day 7 Day 10 Day 14 Blank Group 0.46±0.17 1.45±0.41 1.86±0.38 2.23±0.26 Sample set 0.74±0.21* 2.02±0.27* 2.66±0.16* 2.92±0.08* Control group 1 0.63±0.30* 1.73±0.19*# 2.27±0.32*# 2.51±0.27*# Control group 2 0.65±0.18* 1.56±0.25*# 2.09±0.17*# 2.34±0.12*#

[0094] *: compared with the blank group, p < 0.01; #: compared with the sample group, p < 0.01

[0095] Table 5 New hair length in the hair removal area of ​​each group of mice (x̄±s, n=10)

[0096] Group New hair length / mm Blank Group 5.435±0.315 Sample set 8.172±0.256* Control group 1 7.264±0.301*# Control group 2 7.075±0.184*#

[0097] *: compared with the blank group, p < 0.01; #: compared with the sample group, p < 0.01

[0098] By comparing the growth status and length of new hair in the hair removal areas of each group of mice, it can be clearly found that the plant extract prepared by ginseng (PANAX GINSENG) root extract, Alpinia serrulata (ALPINIASPECIOSA) leaf extract and Cyperus oleifera (CYPERUSESCULENTUS) root oil in a mass ratio of 1~3:2~5:1 can significantly promote hair growth. The three components act synergistically and achieve the best effect under a specific dosage ratio, which has produced significant improvement compared with widely used hair-growing plant extracts such as Polygonum multiflorum root extract and Platycladus orientalis leaf extract.

[0099] Experimental Example 3: Evaluation of Shampoo Usage

[0100] 90 volunteers diagnosed with seborrheic alopecia in the outpatient clinic were selected, with an age range of 25 to 40 years old. The volunteers were randomly divided into 6 groups, with 15 people in each group. Each group used the shampoo prepared by Examples 1 to 3 and Comparative Examples 1 to 3, respectively, and washed once every other day. During washing, the shampoo was used to massage the scalp for at least 3 minutes, and the use was continued for 12 weeks. After 12 weeks, the improvement of dandruff, itchy head, and hair loss was evaluated using a scoring system of 1 to 10 points, with 1 point indicating completely ineffective and 10 points indicating completely effective. The evaluation results are shown in Table 6.

[0101] Table 6 Results of shampoo use evaluation

[0102] Group Dandruff Improvement Improvement of itchy scalp Hair loss improvement Example 1 8.6 8.1 7.2 Example 2 8.4 7.8 7.1 Example 3 8.6 8.2 7.3 Comparative Example 1 7.1 6.7 6.1 Comparative Example 2 6.8 5.9 5.0 Comparative Example 3 7.5 7.0 6.6

[0103] It can be clearly found from the feedback of volunteers that the anti-hair loss and anti-itching shampoo containing plant extracts prepared in Examples 1 to 3 can well improve the symptoms of itchy scalp compared with Comparative Examples 1 to 3, and can effectively alleviate hair loss caused by excessive oil secretion on the scalp, killing two birds with one stone.

[0104] The above contents are further detailed descriptions of the present invention in combination with specific preferred embodiments, and it cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. An anti-hair loss and antipruritic shampoo containing plant extracts, comprising the following components in percentage by mass: 1-15% plant extract, 5-25% surfactant, 0.1%-5% moisturizer, 0.1%-3% conditioner, 0.1%-0.5% anti-dandruff and antipruritic agent, 0.1%-1% ammonium hydroxide, 0.01%-0.1% citric acid, 0.01%-0.1% preservative, 0%-0.5% essence; and the balance of purified water; The mass ratio of ginseng root extract, Alpinia speciosa leaf extract and cyperus esculentus root oil in the plant extract is 2-3:2-5:1; The conditioning agents are chitosan, histidine and amino dimethyl siloxane; The anti-dandruff and antipruritic agent is piroctone olamine salt.

2. The anti-hair loss and anti-itching shampoo according to claim 1, characterized in that: The surfactant is selected from one or a mixture of two or more of sodium cocoyl isethionate, cocamidopropyl betaine, sodium lauroyl glutamate, sodium lauroyl sarcosinate, lauroyl amidopropyl betaine and decyl glucoside.

3. The anti-hair loss and anti-itching shampoo according to claim 2, characterized in that: The surfactants include sodium cocoyl isethionate, sodium lauroyl glutamate and decyl glucoside.

4. The anti-hair loss and anti-itching shampoo according to claim 1, characterized in that: The moisturizing agent is selected from one or a mixture of two or more of propylene glycol, hexylene glycol, glycerin, xylitol, and sodium hyaluronate.

5. The anti-hair loss and anti-itching shampoo according to claim 4, characterized in that: The humectants include hexylene glycol and sodium hyaluronate.

6. The anti-hair loss and anti-itching shampoo according to claim 1, characterized in that: The preservative is selected from any one of benzyl alcohol, sodium benzoate, phenoxyethanol, methylparaben, propylparaben, DMDM ​​hydantoin or a mixture of two or more thereof.

7. The anti-hair loss and anti-itching shampoo according to claim 6, characterized in that: The preservative is phenoxyethanol.

8. A method for preparing an anti-hair loss and antipruritic shampoo containing plant extracts according to any one of claims 1 to 7, comprising the following preparation steps: 1) Heat the surfactant and conditioner to 70-90°C and stir for 20-60 minutes to mix evenly. Keep warm for 10-20 minutes and then cool to 30-45°C to obtain material A. 2) Mix the moisturizer, anti-dandruff and antipruritic agent, ammonium hydroxide, citric acid and purified water, heat to 30-50°C, stir for 20-45 minutes, and mix well to obtain material B; 3) Evenly mix the material A obtained in step 1), the material B obtained in step 2), the plant extract, the preservative and the essence to obtain the anti-hair loss and anti-itching shampoo containing the plant extract.

9. The preparation method according to claim 8, characterized in that: The step 1): heat the surfactant and the conditioner to 75-85° C., stir for 35-45 minutes, mix evenly, keep warm for 10-20 minutes, then cool to 35-45° C. to obtain material A.

10. The preparation method according to claim 9, characterized in that: The step 2): the moisturizer, anti-dandruff and antipruritic agent, ammonium hydroxide, citric acid and purified water are mixed and heated to 35-45° C., stirred for 25-35 minutes, and mixed evenly to obtain material B.

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