Oil-control moisturizing composition, application and cosmetic

Abstract

The invention belongs to the field of new daily chemical materials, and particularly relates to an oil-controlling and moisturizing composition which comprises 0.5-1.5% of PEG-7 glyceryl cocoate, 0.5-1.5% of polyethylene glycol, 0.5-1.5% of polyethylene glycol, 0.5-1.5% 0.1%-1% of PCA sodium; 1% to 3% of bis-PEG-18 methyl ether dimethyl silane; 0.005 to 0.02 percent of salvia officinalis leaf oil; and 0.005 to 0.02% of verbena oil. The composition adopts PEG-7 glyceryl cocoate, PCA sodium and bis-PEG-18 methyl ether dimethyl silane as main components, and adopts sage leaf oil and verbena oil as grease components, so that the comprehensive oil control and moisturizing effects are achieved, the blood microcirculation and micro-ecology of scalp are improved, and dandruff removal, oil control and moisturizing can be effectively realized. Meanwhile, the invention also provides application of the composition.

Description

Technical Field

[0001] The invention belongs to the field of new daily chemical materials, and particularly relates to an oil-controlling and moisturizing composition, application and cosmetics. Background Art

[0002] Dandruff is related to many factors, such as hormones, scalp cleanliness, scalp microecology, etc. Scalp oil secretion is an important scalp health indicator that affects dandruff, itching, and microecological balance;

[0003] The oil secretion of the scalp is related to the individual's endocrine system on the one hand, and is closely related to the blood circulation of the scalp and whether the oil is cleaned in time on the other hand.

[0004] CN118141736A discloses a scalp oil control care composition and a preparation method thereof, which reduces sebum secretion and balances oil by reducing the activity of 5α-reductase and regulating the activity of cyclooxygenase COX-2 through scalp care products, and can also establish a cationic mutual exclusion composition through ion mutual exclusion technology, making the hair roots fluffy under physical action conditions, and preventing the hair from covering the surface of the scalp pores due to gravity, causing pore blockage and oil accumulation. The scalp care product is composed of vanilla extract, fig extract, chamomile extract, argan oil, hydrolyzed keratin, bergamot fruit oil, ginger root oil, red quinoa extract, hydrolyzed hyaluronate zinc, water dragon extract, large-leaf holly leaf extract, ice leaf day flower callus extract, pyridoxine, and capryloyl glycine.

[0005] CN118021662A discloses an oil control composition for scalp, a preparation method and application thereof. The oil control composition for scalp comprises, by weight: 1 to 50 parts of Norway spruce leaf extract, 0.01 to 10 parts of Lotus japonicus seed extract, 0.01 to 10 parts of Sophora japonica bud extract, 0.01 to 15 parts of Anemarrhena asphodeloides root extract, 0.01 to 15 parts of Pueraria root extract and 25 to 85 parts of solvent.

[0006] CN118021663A discloses a scalp soothing oil-controlling essence. The essence uses water as a solvent and, by mass percentage, comprises: 2-10% moisturizer, 1-4% Platycladus orientalis leaf extract, 0.8-2% arginine, 0.01-1% hydrolyzed royal jelly protein, 0.05-0.8% plant complex for reducing scalp sensitivity, 0.2-0.6% antibacterial agent, 0.01-0.6% red clover flower extract, 0.005-0.6% β-nicotinamide mononucleotide, 0.01-0.3% bifida yeast fermentation product filtrate, 0.1-0.2% thickener, 0.001-0.1% Zizyphus joazeiro bark extract, and 0.001-0.06% polypeptide composition.

[0007] Most of the above solutions improve scalp oil secretion through plant extracts, plant oils, amino acids, fermentation products, etc.

[0008] In the long-term research of the applicant, we believe that scalp health is related to at least three aspects: 1. The secretion of healthy oil and the timely and appropriate removal of oil that clogs the pores; 2. The control of scalp blood microcirculation to inhibit the intracellular lipid content; 3. The improvement of the moisturizing properties of the scalp can improve the microecological balance of the scalp.

[0009] Therefore, the technical problem solved in this case is: how to improve the oil control effect of the scalp and how to comprehensively control oil and remove dandruff. Summary of the invention

[0010] Based on this, the first object of the present invention is to provide an oil-controlling and moisturizing composition, which uses PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethyl silane as main ingredients, and uses sage leaf oil and verbena oil as oil components to achieve comprehensive oil control and moisturizing effects, improve scalp blood microcirculation and microecology, and can effectively remove dandruff, control oil, and moisturize.

[0011] The second object of the present invention is to provide the use of the above composition.

[0012] In order to achieve the first invention object, the present invention adopts the following technical solutions:

[0013] An oil-controlling and moisturizing composition, comprising:

[0014] PEG-7 Glyceryl Cocoate 0.5-1.5%;

[0015] Sodium PCA 0.1-1%;

[0016] Bis-PEG-18 methyl ether dimethyl silane 1-3%;

[0017] Sage leaf oil 0.005-0.02%;

[0018] Verbena oil 0.005~0.02%.

[0019] PEG-7 Glyceryl Cocoate is a nonionic surfactant that has the functions of cleaning and thickening. It is also a hydrophilic emollient ester.

[0020] Sodium PCA (sodium pyrrolidone carboxylate) is a naturally occurring substance in the skin. It is an amino acid derivative with strong hygroscopicity and can absorb moisture from the air. It has a stronger moisturizing power than glycerin, propylene glycol, and sorbitol and has good moisturizing properties. At the same time, it has the function of strengthening keratin and is used to enhance the skin's own moisturizing ability.

[0021] Bis-PEG-18 methyl ether dimethyl silane is a commonly used surfactant with good moisturizing and nourishing properties;

[0022] In addition to having good moisturizing properties and promoting the skin to improve its own moisturizing properties, the above three, PEG-7 glyceryl cocoate has the characteristics of good compatibility with oils. When combined with oils, it can significantly improve the spreading and penetration of oils on the scalp; bis-PEG-18 methyl ether dimethyl silane is a water-soluble wax. As a silane derivative, it can have good foaming and oil compatibility characteristics when used in shampoo, and can improve the stability and dispersibility of plant oils in the system.

[0023] Clary Sage Leaf Oil is a very common vegetable oil used on the scalp. It promotes cell regeneration, especially for hair growth in the scalp. It purifies greasy hair and dandruff because it inhibits excessive sebum secretion. It is beneficial for inflamed and swollen skin.

[0024] Verbena oil can deeply condition the scalp and inhibit excessive oil secretion.

[0025] At the same time, sage leaf oil and verbena oil both have a certain function of improving blood microcirculation, which can further improve the oil secretion of scalp cells and maintain the oil secretion of the scalp in a balanced state.

[0026] The efficacy of sage leaf oil and verbena oil is based on an emulsification system that can smoothly deliver them to scalp cells. Combined with the oil compatibility and penetration-promoting functions of PEG-7 glyceryl cocoate and the compatibility and stable dispersion functions of bis-PEG-18 methyl ether dimethyl silane, they can exhibit better functions of inhibiting sebum secretion and promoting cell regeneration when acting on scalp cells.

[0027] Through the mutual cooperation of the above components, the health of the scalp can be effectively improved, excessive oil secretion can be avoided, and the production of dandruff can be effectively inhibited.

[0028] The above-mentioned oil-controlling and moisturizing composition comprises:

[0029] PEG-7 Glyceryl Cocoate 0.8-1.2%;

[0030] Sodium PCA 0.3-0.8%;

[0031] Bis-PEG-18 methyl ether dimethyl silane 1.5-2.5%;

[0032] Sage leaf oil 0.008-0.015%;

[0033] Verbena oil 0.008~0.015%.

[0034] The above-mentioned oil-controlling and moisturizing composition further comprises: one or more combinations of lemon peel oil, citronella oil and ylang-ylang flower oil.

[0035] The above-mentioned oil-controlling and moisturizing composition further comprises:

[0036] Lemon peel oil 0.005-0.02%;

[0037] Citronella oil 0.005-0.02%;

[0038] Ylang ylang flower oil 0.005~0.02%.

[0039] The above-mentioned oil-controlling and moisturizing composition further comprises:

[0040] Meadowfoam seed oil 0.005~0.02%.

[0041] It should be noted that when used alone, meadowfoam seed oil has a certain oil control effect, but its oil control effect is far less than that of sage leaf oil and verbena oil. When used together with sage leaf oil and verbena oil, it can effectively improve the control of oil secretion by plant oil. We believe that the reason for this result is that meadowfoam seed oil has unique skin film-forming, moisturizing and antioxidant properties, which can improve the spreadability, permeability and antioxidant properties of sage leaf oil and verbena oil on the scalp surface, and improve the efficacy of plant oils.

[0042] Meanwhile, the invention also discloses the use of the above composition in preparing cosmetics.

[0043] In the above-mentioned use, the cosmetic is shampoo, conditioner or shampoo cream.

[0044] Finally, the present invention also discloses a shampoo containing the composition as described above.

[0045] The beneficial effects of the present invention are:

[0046] The present invention adopts PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethyl silane as main ingredients, and adopts sage leaf oil and verbena oil as oil components to achieve the effects of comprehensive oil control and moisturizing, improve scalp blood microcirculation and microecology, and can effectively remove dandruff, control oil, and moisturize. DETAILED DESCRIPTION

[0047] The technical solution of the present invention is further described below by specific implementation methods. It should be understood by those skilled in the art that the embodiments are only to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0048] If no specific experimental steps or conditions are specified in the examples, the conventional experimental steps or conditions described in the literature in the field can be used. If no manufacturer is specified for the reagents or instruments used, they are all conventional reagent products that can be obtained commercially.

[0049] Supplier information and / or product information

[0050] PEG-7 Glyceryl Cocoate: provided by BASF (China) Co., Ltd.;

[0051] Sodium PCA: provided by Kunshan Shuangyou Daily Chemical Co., Ltd.;

[0052] Bis-PEG-18 methyl ether dimethyl silane: provided by Guangzhou Dongxiong Chemical Co., Ltd.;

[0053] Sage leaf oil: provided by Guangzhou Liye Flavors & Fragrances Co., Ltd.

[0054] Verbena oil: provided by Guangzhou Liye Flavors & Fragrances Co., Ltd.

[0055] Lemon peel oil: provided by Guangzhou Liye Flavors & Fragrances Co., Ltd.

[0056] Citronella oil: provided by Guangzhou Liye Flavors & Fragrances Co., Ltd.

[0057] Ylang-ylang flower oil: provided by Guangzhou Liye Flavors and Fragrances Co., Ltd.

[0058] Example

[0059] A preparation method of an oil-controlling and moisturizing composition is as follows:

[0060] Step 1: Add bis-PEG-18 methyl ether dimethyl silane raw material into water while stirring, heat to 80°C, completely disperse and dissolve, and stir at a speed of 400-600r / min;

[0061] Step 2: Add PEG-7 glyceryl cocoate raw material, stir until completely dissolved, keep warm for 30 minutes, stirring speed 100-400r / min;

[0062] Step 3: Cool down to 45 degrees, add sodium PCA, sage leaf oil, verbena oil, lemon peel oil, citronella oil, ylang-ylang flower oil, and meadowfoam seed oil (if the above vegetable oils are added in the formula, add them in step 3; if not, ignore the addition of the above components), stirring speed 100-400r / min.

[0063] Its specific formula refers to Table 1;

[0064] Table 1 Recipe

[0065]

[0066] Comparative Example

[0067] Preparation method reference example;

[0068] Recipe Reference Table 2

[0069] Table 2 Recipe

[0070]

[0071]

[0072] Test Example 1: Security Test

[0073] 1. Formula safety test

[0074] The compositions obtained in Examples 1-3 and Example 7 were subjected to the chick chorioallantoic membrane test.

[0075] Control and test sample treatment

[0076] Samples: compositions of Examples 1 to 3 and 7.

[0077] Negative control: normal saline.

[0078] Positive control: 0.1 mol / L NaOH solution.

[0079] Test operation steps

[0080] In this test, 6 chicken embryos were selected for each group, and the conditions of the chorioallantoic membrane were recorded with a camera. A polytetrafluoroethylene resin ring was placed on the chorioallantoic membrane of the chicken embryo and photographed. The sample to be tested was added to the polytetrafluoroethylene resin ring, the time of adding the sample was recorded, and the air chamber was covered with a moistened plastic wrap. The chicken embryo was moved to a constant temperature and humidity chamber for culture, and the degree of change of each toxic effect was observed.

[0081] Calculation results:

[0082] The endpoint evaluation method was used to perform the test, and the endpoint evaluation (ES) was calculated, with the result retained to two decimal places; the score of each chicken embryo = the sum of the bleeding, coagulation and vascular melting observed in each chicken embryo; the average value of the mathematical sum obtained for ES-6 chicken embryos. The average ES score was calculated according to the following formula.

[0083]

[0084] Result judgment criteria:

[0085] ES≤4, non-irritating; 4<ES≤12, mildly irritating; 12<ES<16, moderately irritating; ES≥16, strongly irritating / corrosive.

[0086] The experimental results showed that all samples were non-irritating.

[0087] Test Example 2: Oil control test of the composition

[0088] 1. Test Method

[0089] (1) 5-α-reductase inhibition test

[0090] Treatment of experimental groups

[0091] Sample group: diluted with buffer to a sample concentration of 20%;

[0092] Positive control (finasteride, purity ≥98%): dilute with methanol to a positive control concentration of 0.1%;

[0093] Negative control: Tris-HCl buffer.

[0094] Test steps

[0095] A sample group, a positive control group, a negative control group and a blank group were set up. Three parallels were set up for each group. Different reagent solutions were added to the four groups respectively, and the mixture was shaken well. Each group was subjected to HPLC analysis to determine the testosterone content in each tube.

[0096] Calculation formula

[0097]

[0098] Data analysis

[0099] The statistical analysis software was SPSS, and the comparison of 5-α reductase inhibition rates among the test samples, positive controls, and negative controls was performed using an independent sample t-test. The above statistical analyses were all two-tailed tests, with a significance level of a = 0.05. P ≥ 0.05 indicated that there was no significant difference between the two groups; P < 0.05 indicated that there was a significant difference between the two groups.

[0100] Result judgment criteria

[0101] The 5-α reductase inhibition rate of the sample is higher than that of the negative control and has a significant difference (P < 0.05), which means that the test sample can be considered to have a certain oil control effect.

[0102] (2) Moisturizing performance test

[0103] Experimental methods

[0104] 2.1 Accurately weigh the sample;

[0105] 2.2 Select a control product with moisturizing effect;

[0106] 2.3 Measure the moisture retention rate in a constant temperature and humidity device with set temperature and humidity;

[0107] 2.4 Carry out weighing measurement according to the set time;

[0108] 2.5 Calculate the moisturizing rate at each time point.

[0109] Correlation between experimental indicators and moisturizing efficacy

[0110] Moisture retention rate (%) = (1-(m0-mn) / m0) × 100

[0111] m n -Continuously measure the total mass of the sample in g;

[0112] m0-total mass of the sample at the beginning, in g;

[0113] The control product used in this experiment was 5% glycerin, and the dosage form was consistent with the test sample. The added moisturizer glycerin is a common moisturizer and is widely used in cosmetics.

[0114] 2. Test Results

[0115] (1) The test results of 5-α reductase inhibition rate are shown in Table 4.

[0116] Table 4 5-α reductase inhibition results

[0117]

[0118]

[0119] Result analysis:

[0120] 1. It can be seen from Examples 1 to 3 that the formula of the present invention has a certain oil control effect. From the perspective of dosage, the oil control effect of sage leaf oil is slightly better than that of verbena oil; it can be seen from Comparative Example 6 that PEG-7 glyceryl cocoate, sodium PCA, and bis-PEG-18 methyl ether dimethyl silane contribute to oil control, but not as much as sage leaf oil and verbena oil.

[0121] 2. It can be seen from Example 4 that the addition of white meadowfoam seed oil can significantly promote the oil control effect. It can be seen from Comparative Example 6 that the use of white meadowfoam seed oil alone does not significantly promote the oil control effect, indicating that the channel for the efficacy of white meadowfoam seed oil may be that white meadowfoam seed oil has unique skin film-forming, moisturizing and antioxidant properties, thereby promoting the spreadability, permeability and antioxidant properties of sage leaf oil and verbena oil on the scalp surface, thereby improving the efficacy of plant oils.

[0122] 3. It can be seen from Examples 5, 6 and 7 that lemon peel oil, citronella oil and ylang-ylang flower oil can improve the oil control effect to a certain extent, but the effect is not as good as that of sage leaf oil and verbena oil. It can be seen from Example 7 that in the presence of meadowfoam seed oil, the oil control effect can be significantly improved.

[0123] 4. It can be seen from Comparative Examples 1 and 2 that the use of sage leaf oil and verbena oil alone can achieve a certain oil control effect, among which the use of sage leaf oil alone has a better effect; it can be seen from Comparative Examples 3 and 4 that the combination of sage leaf oil, verbena oil and white meadowfoam seed oil alone can also achieve a good oil control effect.

[0124] (2) The test results of moisturizing performance are shown in Table 5.

[0125] The overall test results of moisturizing rate are not much different. Only the moisturizing rate test results of Example 1, Comparative Example 6 and the glycerol group are shown below.

[0126] Table 5 Moisture retention test results

[0127]

[0128]

[0129] Result analysis:

[0130] It can be seen from Table 5 that the moisturizing effects of the embodiments and comparative examples are similar to those of glycerin, which indicates that the products of the present invention can achieve a relatively good moisturizing effect.

[0131] Application example: A shampoo, the formula of which is shown in Table 6

[0132] Table 6 Recipe

[0133]

[0134]

Claims

1. An oil-controlling and moisturizing composition, characterized in that: include: PEG-7 Glyceryl Cocoate 0.5-1.5%; Sodium PCA 0.1-1%; Bis-PEG-18 methyl ether dimethyl silane 1-3%; Sage leaf oil 0.005-0.02%; Verbena oil 0.005~0.02%.

2. The oil-controlling and moisturizing composition according to claim 1, characterized in that: include: PEG-7 Glyceryl Cocoate 0.8-1.2%; Sodium PCA 0.3-0.8%; Bis-PEG-18 methyl ether dimethyl silane 1.5-2.5%; Sage leaf oil 0.008-0.015%; Verbena oil 0.008~0.015%.

3. The oil-controlling and moisturizing composition according to claim 1, characterized in that: Also includes: One or more combinations of lemon peel oil, citronella oil and ylang-ylang flower oil.

4. The oil-controlling and moisturizing composition according to claim 3, characterized in that: Also includes: Lemon peel oil 0.005-0.02%; Citronella oil 0.005-0.02%; Ylang ylang flower oil 0.005~0.02%.

5. The oil-controlling and moisturizing composition according to any one of claims 1 to 4, characterized in that: Also includes: Meadowfoam seed oil 0.005~0.02%.

6. Use of the composition according to any one of claims 1 to 5 in the preparation of cosmetics.

7. The use according to claim 6, characterized in that The cosmetics are shampoo, conditioner or shampoo cream.

8. A shampoo, characterized in that: Contains the composition according to any one of claims 1 to 5.

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