Cooling and soothing cream with antibacterial and anti-inflammatory effects and preparation method thereof

Abstract

The invention relates to cooling and soothing cream with antibacterial and anti-inflammatory effects and a preparation method of the cooling and soothing cream. According to the cool and refreshing soothing cream, folium artemisiae argyi and mint leaves are used as main raw materials, and various effects of antibiosis, inflammation diminishing, cool and refreshing, itching relieving and the like of natural plants are integrated through a scientific proportion and an innovative preparation process. Clinical tests show that when the cooling and soothing cream is used for treating common skin problems such as mosquito bite, pruritus, redness and swelling, scald caused by hot water and fire and the like, the total effective rate reaches 100%, and any adverse reaction or allergic phenomenon does not occur. The cooling and soothing cream disclosed by the invention not only fills the market blank, but also shows extremely high application value and market prospect due to high safety, low side effect, wide applicability and good user experience. In addition, by optimizing the component proportion, researching the storage stability and standardizing the production process, the quality and stability of the product are further improved.

Description

Technical Field

[0001] The invention relates to the field of medicines, and in particular to a cooling and soothing ointment with antibacterial and anti-inflammatory effects and a preparation method thereof. Background Art

[0002] In the current pharmaceutical and cosmetics market, there are many types of topical medications for common skin problems such as mosquito bites, skin itching, redness and swelling, but most products have problems such as single efficacy, large side effects or poor comfort. Traditional topical medications often focus on single antipruritic or anti-swelling effects, while ignoring the importance of antibacterial and anti-inflammatory effects, resulting in limited treatment effects and easy to cause secondary infections.

[0003] In addition, as people's health awareness increases, they have higher requirements for the safety, comfort and comprehensive efficacy of topical drugs. Consumers not only hope that the products can quickly relieve symptoms, but also hope that they have antibacterial and anti-inflammatory functions to reduce the risk of infection, while also bringing a comfortable and cool feeling during use.

[0004] However, there are few topical drugs on the market that can simultaneously satisfy the multiple effects of cooling, relieving itching, reducing swelling, and antibacterial and anti-inflammatory. Based on this background, the present invention proposes a cooling and soothing cream with antibacterial and anti-inflammatory effects and a preparation method thereof, aiming to maximize the cooling, relieving itching, antibacterial and anti-inflammatory effects of natural plants such as wormwood leaves and mint leaves through scientific proportioning and innovative processes, so as to meet market demand and improve the quality of life of patients. The cooling and soothing cream of the present invention not only significantly improves the therapeutic effect on the basis of traditional topical drugs, but also fills the market gap, and has extremely high application value and market prospects.

[0005] In order to solve the above problems, the applicant proposes a cooling and soothing ointment with antibacterial and anti-inflammatory effects and a preparation method thereof. Summary of the invention

[0006] The object of the present invention is to provide a cooling and soothing ointment with antibacterial and anti-inflammatory effects and a preparation method thereof, so as to solve the problems in the prior art.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a cooling and soothing ointment with antibacterial and anti-inflammatory effects, comprising the following ingredients in weight percentage: 10% to 20% wormwood leaves, 10% to 20% mint leaves, 20% to 25% beeswax, and the remainder is olive oil.

[0008] Optionally, the preparation method of the cooling and soothing ointment includes: cleaning and drying the moxa leaves and mint leaves, soaking them in olive oil according to proportion for 48 hours, heating them in a water bath for 12 hours, filtering out the residue to obtain the extracted oil; adding beeswax to the extracted oil according to proportion, heating it in water until the beeswax is completely melted, pouring the ointment into a container while it is hot, and packaging it after cooling.

[0009] Optionally, the cooling and soothing cream has the effects of cooling, relieving itching, reducing swelling and antibacterial and anti-inflammatory, and is particularly suitable for the treatment of mosquito bites, itching and swelling, burns from water or fire, and eczema skin problems.

[0010] Beneficial effects: Perfect combination of multiple functions: The cooling and soothing cream of the present invention combines multiple active ingredients from natural plants such as wormwood leaves and mint leaves. It not only has a cooling feeling, but also can effectively relieve itching and swelling. More importantly, its unique antibacterial and anti-inflammatory effects fill the gap in similar products on the market. This perfect combination of multiple functions makes the cooling and soothing cream perform well in treating various skin problems such as mosquito bites, itching, redness and swelling, and burns caused by water or fire, providing patients with a comprehensive and efficient solution.

[0011] High safety and low side effects: Since the cooling and soothing cream of the present invention mainly uses natural plant ingredients and contains no or little chemical additives, it is relatively safe and is not likely to cause allergic reactions or adverse reactions during use. In addition, after rigorous clinical trials, the cooling and soothing cream has not been observed to have any significant adverse reactions or side effects while improving the patient's symptoms, ensuring the safety of the patient's medication.

[0012] Wide applicability: The cooling and soothing cream of the present invention is not only suitable for common skin problems such as mosquito bites, itching and redness, but also has a therapeutic effect on various skin diseases such as burns, eczema, etc. Its wide range of applications enables the cooling and soothing cream to meet the needs of different patients and bring health and comfort to more people.

[0013] Good user experience: During use, the cooling and soothing cream can quickly bring a cooling feeling, effectively relieve skin itching and burning sensations, and improve the patient's comfort. At the same time, its fine texture, easy to apply and absorb, makes the use process more convenient and pleasant. DETAILED DESCRIPTION

[0014] The following describes the preferred embodiments of the present invention to make its technical content clearer and easier to understand. The present invention can be embodied in many different forms of embodiments, and the protection scope of the present invention is not limited to the embodiments mentioned in the text.

[0015] Example 1

[0016] Raw material selection and processing

[0017] Artemisia argyi: Artemisia argyi, as one of the key raw materials of the present invention, has significant effects of removing dampness and relieving itching, antibacterial and anti-inflammatory. In terms of raw material selection, we give priority to fresh artemisia argyi because of its high content of active ingredients and better efficacy. If fresh artemisia argyi is not available, dry artemisia argyi can also be used, but it is necessary to ensure that the floating dust is removed and the wormwood is chopped to increase its solubility in olive oil. The dosage range of artemisia argyi is 100g to 200g, and the specific dosage can be adjusted according to the product formula.

[0018] Mint leaves: Mint leaves are another important raw material of the present invention due to their refreshing aroma and significant antipruritic and anti-inflammatory effects. Similar to wormwood leaves, we prefer fresh mint leaves and ensure that only the leaf part is taken, removing the stem and stalk to reduce impurities. The amount of mint leaves used is the same as that of wormwood leaves, which is 100g to 200g.

[0019] Beeswax: Beeswax is a thickener and stabilizer for the paste, and plays an important role in increasing the viscosity of the product and extending the shelf life. In the present invention, the amount of beeswax added is calculated as 20% to 25% of the extracted oil (i.e., the oil after olive oil soaks wormwood leaves and mint leaves) to ensure the stability and use effect of the paste.

[0020] Olive oil: As a solvent and carrier, olive oil can not only effectively extract the active ingredients in wormwood and mint leaves, but also provide good lubricity and skin permeability for the paste. The amount of olive oil used in the present invention is determined according to the total amount of wormwood and mint leaves, which is generally 5 to 10 times the total mass of wormwood and mint leaves.

[0021] Preparation process

[0022] Raw material cleaning and drying

[0023] Wash the selected wormwood leaves and mint leaves separately to remove the dirt and impurities on the surface. After washing, spread the leaves flat and dry them, and be careful to avoid exposure to the sun to prevent the leaves from withering. After drying, weigh the wormwood leaves and mint leaves according to the formula ratio and set aside.

[0024] Soaking and Extraction

[0025] Put the weighed mugwort and mint leaves into the olive oil, making sure that all leaves are covered with oil. Then, seal the container and place it in a cool and ventilated place to soak for 48 hours. During the soaking process, the active ingredients in the mugwort and mint leaves will gradually dissolve in the olive oil. After the soaking, place the container in a water bath and heat it at a temperature between 60℃ and 80℃ for 12 hours. Stir constantly during the heating process to ensure that the oil is heated evenly. After the heating is completed, wait for the oil to cool naturally to room temperature, filter through gauze or filter paper to remove the residue, and obtain the extracted oil.

[0026] Paste preparation

[0027] Cut the beeswax into small pieces according to the proportion and add them to the extracted oil. Then, place the mixture in a water-insulated heater at a temperature between 60℃ and 80℃ and heat until the beeswax is completely melted. Stir constantly during this process to prevent the beeswax from caking. After the beeswax melts, pour the paste into a pre-prepared container (such as a hose, a small can, etc.) while it is still hot, pouring it in two batches to ensure that the paste is evenly distributed. After pouring two-thirds full for the first time, wait for the paste to solidify naturally before pouring the remaining part until the tube is flush. After cooling to room temperature, package and label.

[0028] Clinical trials and efficacy evaluation

[0029] In order to verify the clinical safety and effectiveness of the cooling and soothing ointment of the present invention, we conducted a clinical trial lasting several months. The trial selected 100 volunteers with symptoms such as mosquito bites, itching, redness and swelling, ranging in age from 35 to 76 years old, half of whom were male and half were female.

[0030] Test methods

[0031] Before the test, the affected areas of all volunteers were subjected to routine skin disinfection. Then, an appropriate amount of the cooling and soothing cream of the present invention was applied to the affected areas several times a day. During the test, the volunteers were required to record their feelings and symptom changes after application, and regular follow-up visits were conducted to evaluate the efficacy.

[0032] Efficacy criteria

[0033] The efficacy evaluation refers to the efficacy standards for pruritus in the Practical Diagnosis and Treatment of Integrated Traditional Chinese and Western Medicine, which are divided into the following three levels:

[0034] Cure: Itching and secondary skin damage (such as scratches, blood scabs, and rough skin) completely disappear;

[0035] Significantly effective: the itching symptoms were significantly alleviated, and the secondary skin lesions subsided by more than 80%;

[0036] Ineffective: The pruritus symptoms did not improve or worsened, and the secondary skin lesions subsided by less than 20%.

[0037] Test results

[0038] After several months of clinical trials, the results showed that the cooling and soothing cream of the present invention has achieved significant therapeutic effects in treating symptoms such as mosquito bites, itching, redness and swelling. Among 100 volunteers, 86 cases were cured, 14 cases were significantly effective, and 0 cases were ineffective, with a total effective rate of 100%. No adverse reactions or allergic reactions occurred during the trial, proving that the cooling and soothing cream of the present invention has good safety and effectiveness.

[0039] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the attached claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any mark in the claims should not be regarded as limiting the claims involved.

[0040] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A cooling and soothing ointment with antibacterial and anti-inflammatory effects, characterized in that The invention comprises the following ingredients in percentage by weight: 10% to 20% of mugwort leaves, 10% to 20% of mint leaves, 20% to 25% of beeswax, and the balance is olive oil.

2. The cooling and soothing cream according to claim 1, characterized in that The preparation method of the cooling and soothing ointment comprises: cleaning and drying wormwood leaves and mint leaves, soaking them in olive oil according to proportion for 48 hours, heating them in a water bath for 12 hours, filtering and removing residues to obtain extracted oil; adding beeswax to the extracted oil according to proportion, heating them in water bath until the beeswax is completely melted, pouring the ointment into a container while it is hot, and packaging it after cooling.

3. The cooling and soothing cream according to claim 1 or 2, characterized in that The cooling and soothing ointment has the effects of cooling, relieving itching, reducing swelling and antibacterial and anti-inflammatory, and is particularly suitable for the treatment of mosquito bites, itching and swelling, burns from water or fire, and eczema skin problems.