Biological tissue mashing equipment with cutting structure and use method thereof

Abstract

The invention discloses biological tissue mashing equipment with a cutting structure and a use method of the biological tissue mashing equipment, and belongs to the technical field of biomedical treatment.The biological tissue mashing equipment comprises a supporting frame provided with two sets of supporting columns and a supporting top plate arranged at the tops of the two sets of supporting columns; a lifting frame is slidably mounted between the two supporting columns through a lifting assembly, a material containing barrel is rotatably arranged in the lifting frame, and a rotation assembly is arranged on the lifting frame and used for driving the material containing barrel to rotate. A mashing assembly, a cutting assembly and a material guiding plug block are arranged on the supporting top plate, the mashing assembly comprises a plurality of mashing columns and a mashing column driving assembly, and the mashing columns are installed on the supporting top plate in a sliding mode; the material guiding plug block is fixedly installed at the bottom of the supporting top plate. The cutting assembly is provided with a guide groove which is formed in the upper portion of the mounting top plate, a discharging opening in the bottom of the guide groove penetrates through the mounting top plate and is provided with a cutting cylinder, and a cutting structure is arranged in the cutting cylinder. The raw material mashing device improves the raw material mashing efficiency while ensuring the raw material mashing quality.

Description

Technical Field

[0001] The invention relates to the field of biomedical technology, and in particular to a biological tissue crushing device with a cutting structure and a use method thereof. Background Art

[0002] Biomedicine is a broad concept that involves all methods of using biological macromolecules for treatment. There are many types of biomedicine, which can be divided into non-cell therapy and cell therapy based on the operation mode. Biomedicine is the fourth type of cancer treatment method developed after surgery, radiotherapy and chemotherapy. It uses and stimulates the body's immune response to fight, inhibit and kill cancer cells. With the continuous development of the biomedical industry, people generally accept biomedicine, the biomedical market is extensive, and the demand for biomedical equipment is also increasing.

[0003] In the process of manufacturing biomedical drugs, it is often necessary to crush and mix the raw material samples. In the prior art, the crushing of raw material samples is generally achieved by a biological tissue crusher. However, the existing crushing equipment often has the following problems when in use: First, when the raw material sample is large in volume, if it is directly placed in a crushing container for crushing without being cut and crushed, it will increase the crushing time of the raw material sample and affect the crushing efficiency. The existing crushing equipment cannot achieve efficient crushing operations for raw material samples of larger volumes; second, during the crushing process, the raw material sample will adhere to the inner wall of the container due to the crushing operation, and the existing crushing equipment has poor crushing ability for raw material samples close to the inner wall of the container, which affects the crushing quality of the raw material sample. Summary of the invention

[0004] In view of the problems existing in the prior art, the present invention provides a biological tissue crushing device with a cutting structure and a method of using the same, so as to solve the problem that when the prior art crushing device is used, the raw material samples are directly placed in a crushing container without being cut and crushed, resulting in low crushing efficiency, and the crushing ability of the raw material samples close to the inner wall of the container is poor during the crushing process, affecting the crushing quality.

[0005] The technical solution of the present invention is as follows: In a first aspect of the present invention, a biological tissue crushing device with a cutting structure is provided, comprising: A support frame, the support frame comprising two groups of support columns and a support top plate arranged on top of the two groups of support columns; A lifting frame is slidably installed between the two groups of support columns through a lifting assembly, a material barrel is rotatably arranged in the lifting frame, and a rotary assembly is arranged on the lifting frame to drive the material barrel to rotate; The support top plate is provided with a crushing assembly, a cutting assembly and a material guide plug, the crushing assembly includes a plurality of crushing columns and a crushing column driving assembly, the plurality of crushing columns are slidably mounted on the support top plate, and the plurality of crushing columns can approach or move away from the material holding barrel under the drive of the crushing column driving assembly; The material guide plug is fixedly installed at the bottom position of the corresponding supporting top plate that can abut against the inner wall of the material holding barrel; The cutting assembly is provided with a material guide trough, which is arranged on the upper part of the mounting top plate. The material outlet at the bottom of the material guide trough penetrates the mounting top plate and is provided with a cutting cylinder, in which a cutting structure is provided. In some embodiments of the present invention, the lifting assembly includes two sets of electric slide rails and electric sliders. The two sets of electric slide rails are respectively installed relatively on one side of the two sets of support columns close to the material barrel, and the two sets of electric sliders are respectively installed at both ends of the lifting frame. The two ends of the lifting frame are respectively slidably installed on the electric slide rails through the electric sliders. In some embodiments of the present invention, the rotating assembly includes a fixed ring gear, a driving gear and a rotating drive motor, the rotating drive motor is installed at one end of the lifting frame, the driving gear is coaxially installed on the output shaft of the rotating drive motor, the fixed ring gear is fixedly installed on the outside of the material barrel, and the fixed ring gear is meshed with the driving gear for transmission. In some embodiments of the present invention, the plurality of crushing columns are slidably mounted in guide through holes provided on the support top plate, a crushing piston is elastically mounted on the bottom of the crushing column, and a crushing cone is provided at the bottom of the crushing piston. In some embodiments of the present invention, the bottoms of the plurality of pounding columns are elastically connected to the pounding piston via a coil spring. In some embodiments of the present invention, the pounding column drive assembly includes a reciprocating frame, a turntable and a stepper motor, wherein both ends of the reciprocating frame are respectively connected to the top end of the pounding column, the turntable is arranged on a supporting top plate in the middle of the reciprocating frame and connected to the reciprocating frame, the stepper motor is arranged on the supporting top plate, and the output end of the stepper motor is connected to the turntable.

[0006] In some embodiments of the present invention, the turntable is vertically rotatably mounted on the supporting top plate in the middle of the reciprocating frame through a bracket, the turntable is eccentrically mounted with a fixing column, a limiting groove is horizontally provided in the middle of the reciprocating frame, and the fixing column can be slidably set in the limiting groove. In some embodiments of the present invention, a cutting power motor is provided in the material guide trough, and an output end of the cutting power motor is connected to a cutting structure in a cutting cylinder. In some embodiments of the present invention, the cutting cylinder is detachably connected to the bottom of the material guide trough via threads. In a second aspect of the present invention, a method for using a biological tissue crushing device with a cutting structure is provided, comprising: The lifting assembly drives the lifting frame to move upward, so that the top end surface of the material barrel abuts against the bottom of the supporting top plate, and at this time, the material guide plug abuts against the inner wall of the material barrel; The raw material is placed in the material guide slot of the cutting assembly, and the cutting structure in the cutting cylinder cuts the raw material; The rotating assembly drives the material barrel to rotate; The crushing column driving assembly drives the crushing column to move vertically back and forth to crush the raw materials in the material barrel. During the crushing process, the guide plug guides the raw materials on the inner wall of the material barrel to the middle of the material barrel.

[0007] One or more technical solutions of the present invention have the following beneficial effects: The biological tissue crushing device with a cutting structure and the use method thereof provided by the present invention solve the problem that when the existing crushing device is used, the raw material sample is directly placed in the crushing container without being cut and crushed, resulting in low crushing efficiency, and the crushing ability of the raw material sample close to the inner wall of the container is poor during the crushing process, affecting the crushing quality. Specifically, when the equipment provided by the present invention is in use, the material holding barrel is rotatably installed in the lifting frame, so that the personnel can drive the material holding barrel to descend after the crushing is completed, thereby facilitating the taking of raw materials; by providing a material guide block, in cooperation with the rotating material holding barrel, the raw materials on the inner wall of the material holding barrel are guided to the middle of the material holding barrel, and the crushing piston is cooperated to carry out the crushing process, thereby improving the crushing ability of the raw material samples close to the inner wall of the container, and further improving the crushing quality; by adding a cutting assembly installed on the supporting top plate, the raw materials are cut by the cutting structure in the cutting barrel before being crushed, and large pieces of raw materials are processed into small pieces of raw materials for vibrating, thereby improving the crushing effect of the raw materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0008] Figure 1 This is a schematic diagram of the overall structure of a biological tissue crushing device with a cutting structure provided in Example 1 of the present invention; Figure 2 This is a schematic diagram of the structure of the crushing assembly provided in Example 1 of the present invention; Figure 3 A schematic diagram of the structure of a cutting assembly provided in Example 1 of the present invention; Figure 4 This is a schematic diagram of the component substructure on the support top plate provided in Example 1 of the present invention.

[0009] In the figure: 1. Support column; 2. Support top plate; 3. Electric slide rail; 4. Electric slide block; 5. Lifting frame; 6. Material holding barrel; 7. Fixed gear ring; 8. Driving gear; 9. Rotary drive motor; 10. Mashing column; 11. Reciprocating frame; 12. Coil spring; 13. Mashing piston; 14. Material guide block; 15. Material guide trough; 16. Cutting barrel; 17. Rotating disk; 171. Fixed column; 18. Cutting power motor; 19. Cutting structure. DETAILED DESCRIPTION

[0010] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0011] Example 1 In a typical embodiment of the present invention, a biological tissue crushing device with a cutting structure is provided, comprising: A support frame, the support frame comprises two groups of support columns 1 and a support top plate 2 arranged on the top of the two groups of support columns 1; A lifting frame 5 is slidably installed between the two groups of support columns 1 through a lifting assembly, a material holding barrel 6 is rotatably arranged in the lifting frame 5, and a rotary assembly is arranged on the lifting frame 5 to drive the material holding barrel 6 to rotate; A crushing assembly, a cutting assembly and a material guide plug 14 are provided on the support top plate 2. The crushing assembly includes a plurality of crushing columns 10 and a crushing column driving assembly. The plurality of crushing columns 10 are slidably mounted on the support top plate 2. The plurality of crushing columns 10 can be moved close to or away from the material holding barrel under the drive of the crushing column driving assembly. The material guide plug 14 is fixedly installed at the bottom position of the supporting top plate 2 which can abut against the inner wall of the material storage barrel; The cutting assembly is provided with a material guide trough 15 , which is arranged on the upper part of the mounting top plate. A material outlet at the bottom of the material guide trough 15 penetrates the mounting top plate and is provided with a cutting cylinder 16 , in which a cutting structure 19 is provided. In this embodiment, the lifting frame 5 is slidably mounted on the support column 1 and is driven to lift by the lifting assembly. A material barrel 6 is rotatably mounted on the mounting opening in the lifting frame 5, and a rotary assembly for driving the material barrel 6 to rotate is installed on the lifting frame 5; The crushing assembly is installed on the supporting top plate 2, and includes a crushing column 10. The crushing column 10 is slidably installed in a guide through hole provided on the supporting top plate 2. A crushing piston 13 is elastically installed at the bottom of the crushing column 10. A crushing cone is provided at the bottom of the crushing piston 13. A crushing column driving assembly for driving the crushing column 10 to reciprocate is installed on the supporting top plate 2; The material guide plug 14 is fixedly installed on the bottom of the supporting top plate 2 through a connecting column, and is used to abut against the inner wall of the material barrel, and is used to guide the raw materials at the inner wall of the material barrel to the middle of the material barrel; it can be understood that after the lifting frame 5 is raised to the specified height, the material guide plug 14 can abut against the inner wall of the material barrel 6 without interference, thereby achieving the goal of guiding the raw materials at the inner wall of the material barrel to the middle of the material barrel.

[0012] The cutting assembly is installed on the supporting top plate 2, and includes a material guide trough 15 and a cutting cylinder 16. The material guide trough 15 is fixedly installed on the supporting top plate 2, and the cutting cylinder 16 is installed at the bottom discharge port of the material guide trough 15. A cutting structure 19 is installed in the cutting cylinder 16, and the cutting structure 19 is driven to rotate by a cutting power motor 18 installed in the material guide trough 15; In this embodiment, the lifting frame 5 drives the material holding barrel 6 to rise and fall. After the crushing operation of the raw materials is completed, the material holding barrel 6 descends for the operator to take the materials.

[0013] When the material is discharged, the raw material is put into the material guide trough 15, so that before the raw material is crushed, the cutting structure 19 in the cutting cylinder 16 cuts it, and the large pieces of raw material are processed into small pieces, so as to improve the crushing effect of the raw material.

[0014] Furthermore, the lifting assembly includes two sets of electric slide rails 3 and electric sliders 4. The two sets of electric slide rails 3 are respectively installed on one side of the two sets of support columns 1 close to the material barrel 6, and the two sets of electric sliders 4 are respectively installed at both ends of the lifting frame 5. The two ends of the lifting frame 5 are respectively slidably installed on the electric slide rails 3 through the electric sliders 4. In this embodiment, if Figure 1 As shown, the lifting assembly includes two sets of electric slide rails 3 and electric sliders 4. The two sets of electric slide rails 3 are fixedly installed on the near side of the two sets of support columns 1 respectively. The two sets of electric sliders 4 are fixedly installed at both ends of the lifting frame 5 and slidably installed in the corresponding electric slide rails 3. The two sets of electric sliders 4 slide along the electric rails to drive the lifting frame 5 to move up and down. In other embodiments of the present invention, the lifting operation may also be replaced by other components with lifting driving capabilities, such as a retractable hydraulic cylinder or a pneumatic cylinder.

[0015] Furthermore, the rotary assembly includes a fixed ring gear 7, a driving gear 8 and a rotary drive motor 9. The rotary drive motor 9 is installed at one end of the lifting frame 5, the driving gear 8 is coaxially installed on the output shaft of the rotary drive motor 9, and the fixed ring gear 7 is fixedly installed on the outside of the material barrel 6, and the fixed ring gear 7 is meshed with the driving gear 8 for transmission. In this embodiment, the rotary assembly includes a fixed gear ring 7, a driving gear 8 and a rotary drive motor 9. The rotary drive motor 9 is fixedly mounted on one end of the lifting frame 5, and the driving gear 8 is coaxially mounted on the driving shaft of the rotary drive motor 9. The fixed gear ring 7 is fixedly mounted on the outer side of the material barrel 6 and meshes with the driving gear 8 for transmission. The driving gear 8 is driven to rotate by the rotary drive motor 9, and the material barrel 6 is driven to rotate by the meshing of the fixed gear ring 7. The material barrel 6 drives the raw material to move, and the crushing column 10 is used to crush the raw material.

[0016] Further, such as Figure 4 As shown, a plurality of crushing columns 10 are slidably installed in the guide through holes provided on the supporting top plate 2, a crushing piston 13 is elastically installed at the bottom of the crushing column 10, and a crushing cone is provided at the bottom of the crushing piston 13. Furthermore, the bottoms of the plurality of pounding columns 10 are elastically connected to the pounding piston 13 via a coil spring 12 . Furthermore, the crushing column driving assembly includes a reciprocating frame 11, a turntable 17 and a stepper motor. The two ends of the reciprocating frame 11 are respectively connected to the top end of the crushing column 10. The turntable 17 is arranged on the supporting top plate 2 in the middle of the reciprocating frame 11 and is connected to the reciprocating frame 11. The stepper motor is arranged on the supporting top plate 2, and the output end of the stepper motor is connected to the turntable 17.

[0017] In this embodiment, if Figure 2 As shown, the bottom of the crushing column 10 is elastically connected to the crushing piston 13 through a coil spring 12. When crushing, the bottom of the crushing piston 13 is driven by the coil spring 12 to always press the raw materials to ensure the quality of crushing.

[0018] Furthermore, the turntable 17 is vertically and rotatably mounted on the supporting top plate 2 in the middle of the reciprocating frame 11 through a bracket, and a fixing column 171 is eccentrically mounted on the turntable 17. A limiting groove is horizontally provided in the middle of the reciprocating frame 11, and the fixing column 171 can be slidably set in the limiting groove.

[0019] The crushing column driving assembly includes a reciprocating frame 11, a rotating disk 17 and a stepping motor. Both ends of the reciprocating frame 11 are fixedly connected to the top of the corresponding crushing column 10. The rotating disk 17 is vertically rotatably installed on the supporting top plate 2, and a fixed column 171 is eccentrically installed on the rotating disk 17. The rotating disk 17 is driven to rotate by the stepping motor on the supporting top plate 2. A limit groove for the fixed column 171 to limit the sliding of the fixed column 171 is horizontally provided in the reciprocating frame 11. When the present invention realizes reciprocating movement, the stepping motor drives the rotating disk 17 to rotate, and the fixed column 171 on the rotating disk 17 cooperates with the horizontal limit groove in the reciprocating frame 11 to drive the reciprocating frame 11 to reciprocate and lift, and the reciprocating frame 11 synchronously drives the crushing column 10 to lift and lower; In this embodiment, there are two groups of crushing columns 10, which are symmetrical along the center of the supporting top plate 2 and are respectively fixed at both ends of the reciprocating frame 11. In other embodiments of the present invention, the number of crushing columns 10 can also be increased or decreased according to the specifications of the material holding barrel 6. Furthermore, a cutting power motor 18 is provided in the material guide trough 15 , and an output end of the cutting power motor 18 is connected to a cutting structure 19 in the cutting cylinder 16 . Furthermore, the cutting cylinder 16 is detachably connected to the bottom of the material guide trough 15 via threads. like Figure 3 As shown, in the embodiment, the cutting cylinder 16 is threadedly rotatably installed at the bottom of the material guide trough 15. When personnel clean the cutting structure 19, they can directly rotate the cutting cylinder 16 to remove it from the bottom of the material guide trough 15, which is convenient for personnel to operate.

[0020] In a second aspect of the present invention, a method for using a biological tissue crushing device with a cutting structure is provided, comprising: The lifting assembly drives the lifting frame 5 to move upward, so that the top end surface of the material barrel 6 abuts against the bottom of the supporting top plate 2, and at this time, the material guide plug 14 abuts against the inner wall of the material barrel; The raw material is put into the material guide groove 15 of the cutting assembly, and the cutting structure 19 in the cutting cylinder 16 cuts the raw material; The rotating assembly drives the material container 6 to rotate; The crushing column driving assembly drives the crushing column 10 to move vertically back and forth to crush the raw materials in the material barrel 6. During the crushing process, the material guide block 14 guides the raw materials on the inner wall of the material barrel to the middle of the material barrel.

[0021] In this embodiment, the specific steps include: S1, the lifting assembly drives the lifting frame 5 to slide upward, so that the top end surface of the material holding barrel 6 abuts against the supporting top plate 2; S2, placing the raw material into the material guide trough 15 of the cutting assembly, and cutting the raw material by the cutting structure 19 in the cutting cylinder 16; S3, the rotary assembly drives the material container 6 to rotate; S4, the driving assembly drives the crushing column 10 in the crushing assembly to move vertically back and forth to crush the material in the material holding barrel 6; S4. The material guide plug 14 guides the raw materials on the inner wall of the material barrel to the middle of the material barrel.

[0022] The biological tissue crushing device with a cutting structure and the use method thereof provided by the present invention solve the problem that when the existing crushing device is used, the raw material sample is directly placed in the crushing container without being cut and crushed, resulting in low crushing efficiency, and the crushing ability of the raw material sample close to the inner wall of the container is poor during the crushing process, affecting the crushing quality. Specifically, when the equipment provided by the present invention is in use, the material holding barrel is rotatably installed in the lifting frame, so that the personnel can drive the material holding barrel to descend after the crushing is completed, thereby facilitating the taking of raw materials; by providing a material guide block, in cooperation with the rotating material holding barrel, the raw materials on the inner wall of the material holding barrel are guided to the middle of the material holding barrel, and the crushing piston is cooperated to carry out the crushing process, thereby improving the crushing ability of the raw material samples close to the inner wall of the container, and further improving the crushing quality; by adding a cutting assembly installed on the supporting top plate, the raw materials are cut by the cutting structure in the cutting barrel before being crushed, and large pieces of raw materials are processed into small pieces of raw materials for vibrating, thereby improving the crushing effect of the raw materials.

[0023] Although the above describes the specific implementation mode of the present invention in conjunction with the accompanying drawings, it is not intended to limit the scope of protection of the present invention. Those skilled in the art should understand that various modifications or variations that can be made by those skilled in the art on the basis of the technical solution of the present invention without creative work are still within the scope of protection of the present invention.

Claims

1. A biological tissue crushing device with a cutting structure, characterized in that: include: A support frame, the support frame comprising two groups of support columns and a support top plate arranged on top of the two groups of support columns; A lifting frame is slidably installed between the two groups of support columns through a lifting assembly, a material barrel is rotatably arranged in the lifting frame, and a rotary assembly is arranged on the lifting frame to drive the material barrel to rotate; The support top plate is provided with a crushing assembly, a cutting assembly and a material guide plug, the crushing assembly includes a plurality of crushing columns and a crushing column driving assembly, the plurality of crushing columns are slidably mounted on the support top plate, and the plurality of crushing columns can approach or move away from the material holding barrel under the drive of the crushing column driving assembly; The material guide plug is fixedly installed at the bottom position of the corresponding supporting top plate that can abut against the inner wall of the material holding barrel; The cutting assembly is provided with a material guide trough, which is arranged on the upper part of the mounting top plate. The material outlet at the bottom of the material guide trough penetrates the mounting top plate and is provided with a cutting cylinder, in which a cutting structure is provided.

2. A biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: The lifting assembly includes two sets of electric slide rails and electric sliders. The two sets of electric slide rails are respectively installed on one side of the two sets of support columns close to the material barrel, and the two sets of electric sliders are respectively installed at both ends of the lifting frame. The two ends of the lifting frame are respectively slidably installed on the electric slide rails through the electric sliders.

3. The biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: The rotary assembly includes a fixed gear ring, a driving gear and a rotary drive motor. The rotary drive motor is installed at one end of the lifting frame, the driving gear is coaxially installed on the output shaft of the rotary drive motor, and the fixed gear ring is fixedly installed on the outside of the material holding barrel. The fixed gear ring is meshed with the driving gear for transmission.

4. The biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: The plurality of crushing columns are slidably mounted in guide through holes arranged on the supporting top plate, a crushing piston is elastically mounted on the bottom of the crushing column, and a crushing cone is arranged at the bottom of the crushing piston.

5. The biological tissue crushing device with a cutting structure as claimed in claim 4, characterized in that: The bottoms of the multiple pounding columns are elastically connected to the pounding piston via a coil spring.

6. The biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: The pounding column driving assembly includes a reciprocating frame, a rotating disk and a stepping motor. The two ends of the reciprocating frame are respectively connected to the top end of the pounding column. The rotating disk is arranged on a supporting top plate in the middle of the reciprocating frame and connected to the reciprocating frame. The stepping motor is arranged on the supporting top plate, and the output end of the stepping motor is connected to the rotating disk.

7. The biological tissue crushing device with a cutting structure as claimed in claim 6, characterized in that: The rotating disk is vertically and rotatably mounted on a supporting top plate in the middle of the reciprocating frame through a bracket, a fixing column is eccentrically mounted on the rotating disk, a limiting groove is horizontally provided in the middle of the reciprocating frame, and the fixing column is slidably arranged in the limiting groove.

8. The biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: A cutting power motor is arranged in the material guide trough, and an output end of the cutting power motor is connected to a cutting structure in the cutting cylinder.

9. The biological tissue crushing device with a cutting structure as claimed in claim 1, characterized in that: The cutting cylinder is detachably connected to the bottom of the material guide trough via threads.

10. A method for using a biological tissue crushing device with a cutting structure as claimed in any one of claims 1 to 9, characterized in that: include: The lifting assembly drives the lifting frame to move upward, so that the top end surface of the material barrel abuts against the bottom of the supporting top plate, and at this time, the material guide plug abuts against the inner wall of the material barrel; The raw material is placed in the material guide slot of the cutting assembly, and the cutting structure in the cutting cylinder cuts the raw material; The rotating assembly drives the material barrel to rotate; The crushing column driving assembly drives the crushing column to move vertically back and forth to crush the raw materials in the material barrel. During the crushing process, the guide plug guides the raw materials on the inner wall of the material barrel to the middle of the material barrel.

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