Time jitter correction method for photoacoustic microscopic imaging

The signal offset parameters are determined through an unsupervised learning framework and time jitter correction is performed on the photoacoustic microscopy imaging signal, which solves the problem of time jitter effect in photoacoustic microscopy imaging and improves the accuracy and resolution of the imaging signal.

CN119689443AActive Publication Date: 2025-03-25SUN YAT SEN UNIV
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Patent Information

Application Number
CN202411551633.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-01
Publication Date
2025-03-25
Estimated Expiration
2044-11-01

AI Technical Summary

Technical Problem

In photoacoustic microscopy, due to the laser pulse instability and the delay in the response of electronic devices, the time when the detector receives the photoacoustic signal is inaccurate, and a time jitter effect occurs, affecting the axial positioning accuracy of the three-dimensional reconstruction image.

Method used

Using an unsupervised learning framework, unsupervised training is obtained by obtaining the original photoacoustic signal, signal offset parameters are determined, and time jitter correction is used to correct the original photoacoustic signal to obtain a high-precision target photoacoustic signal.

Benefits of technology

It effectively improves the accuracy of photoacoustic microscopy signal sampling, improves the imaging resolution, and meets the needs of high-precision imaging without improving the hardware of the photoacoustic microscopy imaging system or performing model training.

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Abstract

The invention discloses a time jitter correction method for photoacoustic microscopic imaging. The method comprises the following steps: acquiring an original photoacoustic signal; the original photoacoustic signal comprises a time signal; performing unsupervised training based on the original photoacoustic signal, and determining a signal offset parameter corresponding to the original photoacoustic signal; the signal offset parameter is related to the time signal; and performing time jitter correction on the original photoacoustic signal by using the signal offset parameter to obtain a corrected target photoacoustic signal, so that the sampling precision of the photoacoustic microscopic imaging signal can be effectively improved.
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