Intelligent monitoring and management method and system for postoperative care of tumor patient

Abstract

The invention discloses an intelligent monitoring and management method and system for postoperative care of tumor patients, and relates to the field of data analysis, and the main scheme is as follows: calculating a postoperative care state value # imgabs5 # according to a stability index # imgabs0 #, an equilibrium index # imgabs1 #, a wound inflammation immune response index # imgabs2 #, a pain tolerance and psychological toughness association index # imgabs3 # and a body temperature and immune response index # imgabs4 #; the problem that evaluation indexes are not comprehensive enough, are limited to basic vital sign data and meanwhile ignore relevance among different types of data, so that evaluation accuracy is reduced is solved, the body state of the user is judged according to the nursing state value # imgabs6 # and the nursing state threshold set, the body state of the patient can be accurately judged, and the evaluation accuracy is improved. And the efficiency and the pertinence of nursing work can be improved.

Description

Technical Field

[0001] The present invention relates to the technical field of data analysis, and in particular to an intelligent monitoring and management method and system for postoperative care of tumor patients. Background Art

[0002] In the medical field, intelligent monitoring and management methods and systems for postoperative care of cancer patients can improve the quality of care, formulate personalized care plans based on the individual conditions of patients, help promote the rational allocation of medical resources, optimize the workflow of medical staff, improve the medical service system and improve the quality of medical care.

[0003] The working principle of traditional intelligent monitoring and management methods and systems is: collect the patient's vital signs data, conduct a comprehensive assessment of the patient's postoperative care status based on the collected data, judge the postoperative care effect based on the assessment results, and determine the care goals and methods.

[0004] The existing technology still has the following shortcomings: the evaluation indicators are not comprehensive enough and are limited to basic vital signs data, while ignoring the impact of wound data, home care conditions, etc., and also ignoring the correlation between different types of data, resulting in reduced evaluation accuracy. Summary of the invention

[0005] 1. Technical issues to be resolved In view of the shortcomings of the prior art, the present invention provides an intelligent monitoring and management method and system for postoperative care of tumor patients. , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , which solves the problem that the evaluation indicators are not comprehensive enough, are limited to basic vital signs data, and ignore the correlation between different types of data, resulting in reduced evaluation accuracy.

[0006] (II) Technical solution To achieve the above objectives, the present invention is implemented through the following technical solutions: an intelligent monitoring and management method for postoperative care of tumor patients, comprising: Collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological status data; Calculation of stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , based on physiological function data and immune defense response indicators Calculate body temperature and immune response index ; According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; According to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

[0007] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients: calculating the stability index The method is: Physiological function data at least includes vital signs values , average value of vital signs and measure vital signs ; Drug data including drug metabolic half-life ; Calculation of stability index based on physiological function data and drug data , the formula based on is:

[0008] in, During the drug use cycle The patient's vital signs at each time point; is the serial number corresponding to different time points in the drug use cycle, and its value is ; is the total number of different time points, which is a positive integer; For the The metabolic half-life of the drug; is the serial number corresponding to different drugs, and its value is ; The total amount of medication used in the current cycle.

[0009] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients: calculating the balance index The method is: Physiological function data also includes the patient's actual heart rate value , basic heart rate value , maximum heart rate ,height and weight ; Nutritional data including maximum metabolic equivalents , energy intake value , serum albumin content and ideal body mass index ; According to the patient's actual heart rate , basic heart rate value , maximum heart rate , maximum metabolic equivalent and energy intake Calculate actual metabolic equivalents , the formula based on is:

[0010] According to the patient's height ,weight , serum albumin content and ideal body mass index Calculating nutrient reserves , the formula based on is:

[0011] in, Serum albumin content The weight coefficient is between 0.4 and 0.6; is the weight coefficient of physical fitness index, ranging from 0.4 to 0.6; and 1; According to the actual metabolic equivalent and nutritional reserve value Calculate the balance index , the formula based on is: .

[0012] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients, the wound inflammatory immune response index is calculated. The method is: Wound data including initial wound area , initial wound depth , wound area at this time The depth of the wound , wound edge score and wound redness and swelling score ; Calculate wound data indicators based on wound data , the formula based on is:

[0013] Immune function data include at least inflammatory factor concentrations and immune cell infiltration scores ; Calculate immune function indexes based on immune function data , the formula based on is:

[0014] in, For the The concentration of inflammatory factors, is the serial number corresponding to different inflammatory factors, and its value is ; is the total amount of inflammatory factors; For the The infiltration degree of immune cells was scored. is the serial number corresponding to different immune cells, and its value is ; is the total number of immune cells; According to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index , the formula based on is:

[0015] in, Wound data indicator The weight coefficient is between 0.3 and 0.7; Scoring immune function The weight coefficient is between 0.3 and 0.7; and 1.

[0016] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of cancer patients: calculating the correlation index between pain tolerance and psychological resilience The method is: Pain data including pain tolerance score ; Psychological status data including psychological status scores ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data , the formula based on is:

[0017] in, For the The patients' pain tolerance scores at the second observation were For different observation times, the value is ; is the total number of observations, which is a positive integer; For the The patient's mental status score at the second observation.

[0018] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients: calculating the immune defense response index The method is: Immune function data also includes neutrophil chemotaxis function score , the number of macrophages engulfing the target Total number of macrophages , serum concentration , lower limit of normal serum concentration and upper limit of normal serum concentration ; Calculate immune defense response index based on immune function data , the formula based on is:

[0019] in, For the Neutrophil chemotaxis function score at the first observation; For the The number of macrophages engulfing the target during the first observation; For the The total number of macrophages at the time of observation; For the Serum concentrations of patients during the observation period.

[0020] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients: calculating body temperature and immune response index The method is: Physiological function data also includes patient temperature and average body temperature ; According to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index , the formula based on is:

[0021] in, For the The patient's temperature at the time of the first observation.

[0022] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients, the postoperative care status value is calculated. The method is: According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , the formula based on is: .

[0023] In the preferred embodiment of the intelligent monitoring and management method for postoperative care of tumor patients, the management method is determined according to different user physical conditions, specifically: The set of physical condition thresholds includes a good threshold and medium threshold ; According to the postoperative care status value The nursing status threshold set is used to determine the user's physical status based on the following criteria:

[0024] When the user is in good physical condition, choose management method 1; When the user's physical condition is moderate, choose management method 2; When the user is in poor physical condition, choose management method three.

[0025] The present invention also discloses an intelligent monitoring and management system for postoperative care of tumor patients, comprising: A data collection module is used to collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological state data; Index calculation module, which can calculate stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , according to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index ; The judgment module can be based on the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; According to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

[0026] (III) Beneficial effects The present invention provides an intelligent monitoring and management method and system for postoperative care of tumor patients, which has the following beneficial effects: (1) By collecting the patient's physiological function data, drug data, nutritional data, wound data, immune function data, pain data, and psychological state data, it can enrich the data type and provide effective data for subsequent calculations.

[0027] (2) Calculate the stability index based on physiological function data and drug data , which can reflect the stability of the patient's physiological state under the action of drugs in real time. Calculate the actual metabolic equivalent based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index , can accurately understand the patient's energy metabolism and nutritional reserve level, and promptly detect whether the patient is at nutritional risk. and immune function indicators Calculation of wound inflammatory immune response index , which helps medical staff to more accurately judge the wound healing process and promptly detect potential infection or poor healing problems. The pain tolerance and psychological resilience correlation index is calculated based on pain data and psychological state data , can more comprehensively understand the patient's subjective feelings and psychological coping ability. Calculate immune defense response index based on immune function data , based on physiological function data and immune defense response indicators Calculate body temperature and immune response index , which can help medical staff understand the patient's immune system's defense capabilities after surgery.

[0028] (3) According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , avoiding the limitation of evaluating the condition based on subjective experience or a single indicator, solving the problem that the evaluation indicators are not comprehensive enough, limited to basic vital signs data, and ignoring the correlation between different types of data, resulting in reduced evaluation accuracy. The user's physical condition is judged by the nursing status threshold set, which can accurately judge the patient's physical condition and help improve the efficiency and pertinence of nursing work. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 The present invention discloses a working step schematic diagram of an intelligent monitoring and management method for postoperative care of tumor patients. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] See also Figure 1 The present invention provides an intelligent monitoring and management method for postoperative care of tumor patients, comprising the following steps: Step 1: Collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological state data.

[0032] Combined with the content of step 1: By collecting patients' physiological function data, drug data, nutritional data, wound data, immune function data, pain data and psychological state data, it is possible to enrich data types and provide effective data for subsequent calculations.

[0033] Step 2: Calculate the stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , based on physiological function data and immune defense response indicators Calculate body temperature and immune response index .

[0034] Step 2 includes the following steps: Step 201: Calculate the stability index The method is: Physiological function data at least includes vital signs values , average value of vital signs and measure vital signs .

[0035] It should be noted that the vital signs It is a comprehensive value of physiological indicators that reflect the basic life activities of patients. Physiological indicators include heart rate, blood pressure and respiratory rate. The heart rate value is obtained through an electrocardiogram monitor, the blood pressure value is measured by a mercury sphygmomanometer, and the respiratory rate is determined by medical staff observing the ups and downs of the patient's chest or abdomen. The measured heart rate, blood pressure and respiratory rate are normalized and added together to obtain the vital sign value. . Mean values ​​of vital signs It refers to the average of the vital sign values ​​measured multiple times within a certain time range. It is determined by taking multiple vital sign measurements within a set time range, calculating the vital sign value at each measurement, and then dividing it by the number of measurements.

[0036] Drug data including drug metabolic half-life .

[0037] It should be noted that the drug metabolic half-life It refers to the time required for the amount of different drugs in the body to drop by half. It is an important indicator to measure the speed of drug elimination in the body. It is determined by consulting the drug instructions and drug research literature.

[0038] Calculation of stability index based on physiological function data and drug data , the formula based on is:

[0039] in, During the drug use cycle The patient's vital signs at each time point; is the serial number corresponding to different time points in the drug use cycle, and its value is ; is the total number of different time points, which is a positive integer; For the The metabolic half-life of the drug; is the serial number corresponding to different drugs, and its value is ; The total amount of medication used in the current cycle.

[0040] It should be noted that this formula calculates the vital sign value at each time point Average value of vital signs The ratio of the sum of the squares of the deviations to the number of measurements reflects the fluctuation of vital sign values ​​during the drug use cycle. By calculating the sum of the metabolic half-lives of different drugs, the metabolic rate of the drug in the body is reflected. Taking into account the influence of vital sign fluctuations and drug metabolic rate, the stability index is obtained. The greater the fluctuation of vital signs, the slower the drug metabolism rate and the higher the stability index. The smaller it is, the worse the patient's physical condition is.

[0041] Step 202: Calculate the balance index The method is: Physiological function data also includes the patient's actual heart rate value , basic heart rate value , maximum heart rate ,height and weight .

[0042] It should be noted that the patient's actual heart rate It refers to the heart rate value of the patient measured each time, which reflects the current working state of the patient's heart and is obtained through an electrocardiogram monitor. It refers to the heart rate of a person in an awake, quiet, fasting, and room temperature environment. It represents the heart rate of a person in the most basic physiological state. Collect the heart rate values ​​of healthy people in an awake, quiet, fasting, and room temperature environment and calculate their average value as the basic heart rate value. . Maximum heart rate value It refers to the highest heart rate that the human body can reach when doing strenuous exercise. The maximum heart rate value is calculated by calculating the average of the maximum heart rate values ​​of healthy people of different genders and ages when doing exercise treadmill tests. ;height The body weight was measured by a body measuring instrument. Measured using a body weight scale.

[0043] Nutritional data including maximum metabolic equivalents , energy intake value , serum albumin content and ideal body mass index .

[0044] It should be noted that the maximum metabolic equivalent It refers to the metabolic equivalent value that an individual can achieve when performing maximum intensity exercise. 18 Patient age. Energy intake It refers to the total amount of energy that the human body consumes through diet. By recording the types and quantities of food consumed by the patient in detail, the intake of each food is converted into energy value, and finally the energy intake value is accumulated. . Serum albumin content It refers to the number of grams of albumin per liter of serum of the patient. It is an important indicator reflecting the nutritional status of the body and the synthetic function of the liver. It is determined by collecting venous blood from the patient and testing it with a biochemical analyzer. Body mass index is currently a commonly used standard to measure the fatness and health of the human body. When the body mass index is in the ideal body mass index range, it means that the body's fat content and nutritional status are relatively balanced, and there are relatively few health hazards. According to the World Health Organization, the ideal body mass index range is specifically as follows: For people aged 0 to 18, the ideal body mass index range is from the 5th percentile to the 85th percentile of the growth curve. The growth curve is drawn based on the distribution of body mass index of people aged 0 to 18 years of different ages and genders. For people aged 18 to 60, the ideal body mass index range is 18.5 to 24.9. For people over 60 years old, the ideal body mass index range is 20 to 27. Ideal body mass index It is calculated by (the upper limit of the ideal body mass index range for the corresponding age group + the lower limit of the ideal body mass index range for the corresponding age group) / 2.

[0045] According to the patient's actual heart rate , basic heart rate value , maximum heart rate , maximum metabolic equivalent and energy intake Calculate actual metabolic equivalents , the formula based on is:

[0046] It should be noted that this formula calculates the actual metabolic equivalent through the energy intake value and the metabolic equivalent adjustment value based on heart rate. is the standardized heart rate value of the patient.

[0047] According to the patient's height ,weight , serum albumin content and ideal body mass index Calculating nutrient reserves , the formula based on is:

[0048] It should be noted that the operating principle of this formula is: is the patient's body mass index, and the body mass index is obtained by calculating the ratio between the patient's body mass index and the ideal body mass index. and body mass index to obtain the nutritional reserve value .

[0049] in, Serum albumin content The weight coefficient is 0.4 to 0.6, depending on the serum albumin content. Nutrient reserve value The degree of impact is determined. is the weight coefficient of the body mass index, ranging from 0.4 to 0.6, and is used to determine the nutritional reserve value based on the body mass index. The degree of impact is determined. 1.

[0050] According to the actual metabolic equivalent and nutritional reserve value Calculate the balance index , the formula based on is:

[0051] It should be noted that this formula calculates the actual metabolic equivalent and nutritional reserve value The relative ratio between them gives the balance index The smaller the ratio, the worse the nutritional reserve and the balance index. The smaller.

[0052] Step 203: Calculate wound inflammatory immune response index The method is: Wound data including initial wound area , initial wound depth , wound area at this time The depth of the wound , wound edge score and wound redness and swelling score .

[0053] It should be noted that the initial wound area It refers to the first measurement of the wound surface area after the operation. Refers to the wound surface area measured during wound treatment and care. For shallow wounds, the area is measured directly using a measuring tool. For deep wounds or complex wounds, the area is measured using a two-dimensional ultrasound image. Initial wound depth It refers to the vertical distance from the skin surface to the deepest part of the wound. It refers to the vertical depth of the wound measured at a specific time point during the postoperative wound treatment process. The wound depth is measured by observing the structure of the wound from the skin surface to the deep tissue through ultrasound examination. Wound Edge Score It is a quantitative assessment of the wound edge status. By collecting a large amount of wound image data with manually annotated wound edge scores, the decision tree model is trained. After multiple iterations of training, the model can identify the wound edge features in the wound image data and score them. The patient's wound image data is input into the trained decision tree model to obtain the wound edge score. Wound redness and swelling score It is an indicator used to quantify the redness and swelling of the skin around the wound. The decision tree model is trained by collecting a large amount of wound image data that has been manually annotated with wound redness and swelling scores. After multiple iterations of training, the model can identify the wound redness and swelling in the wound image data and score it. The patient's wound image data is input into the trained decision tree model to obtain the wound redness and swelling score. .

[0054] Calculate wound data indicators based on wound data , the formula based on is:

[0055] It should be noted that this formula calculates the changes in wound area and wound depth after care, and comprehensively considers the wound edge and the degree of wound redness and swelling to obtain the wound data index. .

[0056] Immune function data include at least inflammatory factor concentrations and immune cell infiltration scores .

[0057] It should be noted that the concentration of inflammatory factors It is a class of small molecule proteins synthesized and released by the body's immune cells and certain non-immune cells, such as vascular endothelial cells and epidermal cells. They play an important regulatory role in the inflammatory response process. The concentration of inflammatory factors refers to the content of these inflammatory factors in body fluids such as blood, tissue fluid, and wound exudate. The determination method is: collect blood from patients in the early morning on an empty stomach, and use immunoturbidimetry to determine the concentration of inflammatory factors. The degree of immune cell infiltration refers to the degree to which various neutrophils, macrophages, lymphocytes and other immune cells migrate from the blood and aggregate into the tissue in inflamed or diseased tissues. Immune cell infiltration degree score It is a method for quantitative assessment of this infiltration phenomenon. The score is based on the number of immune cells observed under a high-power microscope (×400), with the specific criteria being: 0 points for no immune cell infiltration, 3 points for less than 10 cells per high-power microscope field, 6 points for 10 to 50 cells per high-power microscope field, and 9 points for more than 50 cells per high-power microscope field.

[0058] Calculate immune function indexes based on immune function data , the formula based on is:

[0059] It should be noted that this formula calculates the concentration of different inflammatory factors and the infiltration degree of different immune cells to obtain the immune function index. The higher the concentration of inflammatory factors, the worse the wound healing effect, and the immune function index The higher the infiltration score of immune cells, the better the wound healing effect, and the immune function index The higher.

[0060] in, For the The concentration of inflammatory factors, is the serial number corresponding to different inflammatory factors, and its value is ; is the total amount of inflammatory factors; For the The infiltration degree of immune cells was scored. is the serial number corresponding to different immune cells, and its value is ; is the total number of immune cells.

[0061] According to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index , the formula based on is:

[0062] in, Wound data indicator The weight coefficient is 0.3 to 0.7, based on the wound data index. Wound inflammatory immune response index importance determined. Scoring immune function The weight coefficient is 0.3 to 0.7, based on the immune function index. Wound inflammatory immune response index The importance of 1.

[0063] It should be noted that this formula comprehensively considers wound data indicators and immune function indicators wound inflammatory immune response index . Wound data indicators and immune function indicators The higher the value, the better the recovery effect. Wound Inflammatory Immune Response Index The higher.

[0064] Step 204: Calculate the correlation index between pain tolerance and psychological resilience The method is: Pain data including pain tolerance score .

[0065] It should be noted that the pain tolerance score It is an assessment method used to quantify an individual's tolerance to pain. The determination method is: the patient fills in a simple pain assessment scale, which includes three aspects: pain level, impact on daily life, and emotional changes caused by pain. Each aspect has a simple description and a corresponding scoring level. In terms of pain level, 0 points means no pain, 1 to 3 points means mild pain, 4 to 6 points means moderate pain, and 7 to 10 points means severe pain. In terms of the impact on daily life, 0 points means no impact, 1 to 3 points means mild impact, 4 to 6 points means moderate impact, and 7 to 10 points means severe impact. In terms of emotional changes caused by pain, 0 points means good mood, 1 to 3 points means occasional bad mood, 4 to 6 points means frequent bad mood, and 7 to 10 points means always bad mood. Patients choose the corresponding score according to their true feelings, and the score obtained by adding the three scores is used as the pain tolerance score. The simple pain assessment scale is often used to assess the patient's pain level, monitor changes in the patient's pain, and understand the impact of pain on the patient's overall quality of life.

[0066] Psychological status data including psychological status scores .

[0067] It should be noted that the psychological status score It is a way to quantitatively evaluate an individual's psychological condition. The patient chooses an appropriate rating level after each item in the symptom self-rating scale based on his or her actual feelings in the past week, and calculates the total score of all items to get the psychological state score. .

[0068] Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data , the formula based on is:

[0069] in, For the The patients' pain tolerance scores at the second observation were For different observation times, the value is ; is the total number of observations, which is a positive integer; For the The patient's mental status score at the second observation.

[0070] It should be noted that the operating principle of this formula is: The product of the pain tolerance score and the psychological state score obtained in each observation was accumulated, reflecting the relationship between the patient's pain tolerance and psychological state at each observation. The pain tolerance and psychological resilience correlation index is obtained by comprehensively considering the pain data and psychological state data. .

[0071] Step 205: Calculate immune defense response index The method is: Immune function data also includes neutrophil chemotaxis function score , the number of macrophages engulfing the target Total number of macrophages , serum concentration , lower limit of normal serum concentration and upper limit of normal serum concentration .

[0072] It should be noted that the neutrophil chemotaxis function score It is a quantitative indicator used to evaluate the ability of neutrophils to move toward chemical stimuli. The chemotaxis of neutrophils was observed and scored using the agarose plate method. The specific criteria are: when the area covered by the neutrophil migration track is greater than 10 mm², the neutrophil chemotaxis function score is The score of neutrophil chemotaxis function is 10 points. When the area covered by the neutrophil migration track is between 3 and 10 mm², the score of neutrophil chemotaxis function is When the area covered by the neutrophil migration track is less than 3 mm², the neutrophil chemotaxis function score is It is 3 points.

[0073] The number of macrophages engulfing the target It refers to the number of macrophages that can engulf a specific target in a specific sample. Macrophages are co-cultured with the labeled target in vitro, and after a certain period of time, the number of macrophages that have engulfed the target is observed and counted under a microscope.

[0074] Total number of macrophages Refers to the total number of macrophages in a specific test sample. Fluorescently labeled antibodies are used to specifically identify markers on the surface of macrophages, and the labeled cells are detected and counted using a flow cytometer.

[0075] Serum concentration It refers to the content of certain substances in serum, such as proteins, hormones, antibodies, cytokines, etc. It is an important indicator reflecting the physiological and pathological state of the body. It is determined by biochemical analyzer.

[0076] Lower limit of normal serum concentration and upper limit of normal serum concentration Refers to the concentration range of a substance in the serum of healthy people. The lower limit is the lowest normal limit of the serum concentration of the substance, and the upper limit is the highest normal limit. Exceeding this range may indicate that the body has some physiological abnormality or disease state. Blood samples are collected from representative healthy people of different regions, ages, genders, etc., and serum is separated. The target substance in the serum is tested. The test results are processed and the lower limit of normal serum concentration is calculated. The upper limit of normal serum concentration is the mean value minus 2 times the standard deviation. The mean value plus 2 times the standard deviation.

[0077] Calculate immune defense response index based on immune function data , the formula based on is:

[0078] in, For the Neutrophil chemotaxis function score at the first observation; For the The number of macrophages engulfing the target during the first observation; For the The total number of macrophages at the time of observation; For the Serum concentrations of patients during the observation period.

[0079] It should be noted that the operating principle of this formula is: The ratio of macrophages that can phagocytize the target to the total macrophages is multiplied by 10 to obtain the actual efficiency score of macrophages in immune defense. The relative position of serum concentration relative to the normal serum concentration range, multiplied by 10, is the serum concentration score. This formula takes into account macrophages, serum concentration, and neutrophil chemotaxis to obtain the immune defense response index. .

[0080] Step 206: Calculate body temperature and immune response index The method is: Physiological function data also includes patient temperature and average body temperature .

[0081] It should be noted that the patient's temperature The average body temperature is determined by measuring with a thermometer. It is calculated by adding the patient's temperature measured over a certain period of time and then dividing by the number of measurements.

[0082] According to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index , the formula based on is:

[0083] in, For the The patient's temperature at the time of the first observation.

[0084] It should be noted that It is the sum of the absolute values ​​of the product of the deviation of the body temperature value from the average body temperature and the deviation of the immune defense response index from the average immune defense response index at each observation. This part reflects the synergistic relationship between the fluctuation of body temperature value and the fluctuation of immune defense response index. It normalizes the overall change of body temperature and immune defense response index. The influence of body temperature and immune response index .

[0085] Combined with the contents of step 201 to step 206: Calculation of stability index based on physiological function data and drug data , which can reflect the stability of the patient's physiological state under the action of drugs in real time. Calculate the actual metabolic equivalent based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index , can accurately understand the patient's energy metabolism and nutritional reserve level, and promptly detect whether the patient is at nutritional risk. and immune function indicators Calculation of wound inflammatory immune response index , which helps medical staff to more accurately judge the wound healing process and promptly detect potential infection or poor healing problems. The pain tolerance and psychological resilience correlation index is calculated based on pain data and psychological state data , can more comprehensively understand the patient's subjective feelings and psychological coping ability. Calculate immune defense response index based on immune function data , based on physiological function data and immune defense response indicators Calculate body temperature and immune response index , which can help medical staff understand the patient's immune system's defense capabilities after surgery.

[0086] Step 3: Based on the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; According to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

[0087] Step 3 includes the following steps: Step 301: Calculate postoperative care status value The method is: According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , the formula based on is:

[0088] It should be noted that this formula obtains the postoperative care status value by considering data from multiple dimensions. .

[0089] Step 302: Determine the management method according to different user physical conditions, specifically: The set of physical condition thresholds includes a good threshold and medium threshold .

[0090] It should be noted that the good threshold and medium threshold The determination method is: collect historical data of different patients and calculate the postoperative care status value in the above way, screen out the higher 50% postoperative care status values ​​and calculate their average and standard deviation. The medium threshold is determined by adding 2 times the standard deviation to the mean value. The value was determined by subtracting 2 times the standard deviation from the mean.

[0091] According to the postoperative care status value The nursing status threshold set is used to determine the user's physical status based on the following criteria:

[0092] When the user is in good physical condition, choose management method 1; When the user's physical condition is moderate, choose management method 2; When the user is in poor physical condition, choose management method three.

[0093] Specifically, management method one is: check the patient's wound once a day, evaluate the patient's physical recovery and psychological state once a month, and urge the patient to perform moderate aerobic exercise. At this time, the management method mainly focuses on promoting further recovery of the body, preventing complications and maintaining good health.

[0094] Management method 2 is as follows: check the patient's wound 2 to 3 times a day, assess the patient's physical recovery and psychological state once a week, conduct a nutritional assessment once a month, and increase the frequency of vital signs monitoring. At this time, the management method needs to be more detailed and targeted.

[0095] Management method three is as follows: check the patient's wound 3 to 4 times a day, assess the patient's physical recovery and psychological state every 3 days, conduct a nutritional assessment once a week, continuously monitor the patient's vital signs, and record the patient's discomfort symptoms in detail, such as the location, degree, and nature of the pain, increase the frequency of laboratory examinations, and perform imaging examinations when necessary.

[0096] Combined with the contents of step 301 to step 302: According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , avoiding the limitation of evaluating the condition based on subjective experience or a single indicator, solving the problem that the evaluation indicators are not comprehensive enough, limited to basic vital signs data, and ignoring the correlation between different types of data, resulting in reduced evaluation accuracy. The user's physical condition is judged by the nursing status threshold set, which can accurately judge the patient's physical condition and help improve the efficiency and pertinence of nursing work.

[0097] On the other hand, the present invention also discloses an intelligent monitoring and management system for postoperative care of tumor patients, which is used to implement the above-mentioned intelligent monitoring and management method, including: A data collection module is used to collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological state data; Index calculation module, which can calculate stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , according to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index ; The judgment module can be based on the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; According to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

[0098] The above embodiments may be implemented in whole or in part by software, hardware, firmware or any other combination thereof. When implemented using software, the above embodiments may be implemented in whole or in part in the form of a computer program product. A person of ordinary skill in the art may appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein may be implemented in electronic hardware or in combination with computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution.

[0099] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0100] The above description is only a specific implementation manner of the present application, but the protection scope of the present application is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present application, which should be included in the protection scope of the present application.

Claims

1. An intelligent monitoring and management method for postoperative care of tumor patients, characterized in that: The following steps are involved: Collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological status data; Calculation of stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , based on physiological function data and immune defense response indicators Calculate body temperature and immune response index ; According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; according to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

2. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 1, characterized in that: Calculating the stability index The method is: Physiological function data at least includes vital signs values , average value of vital signs and measure vital signs ; Drug data including drug metabolic half-life ; Calculation of stability index based on physiological function data and drug data , the formula based on is: in, During the drug use cycle The patient's vital signs at each time point; is the serial number corresponding to different time points in the drug use cycle, and its value is ; is the total number of different time points, and its value is a positive integer; For the The metabolic half-life of the drug; is the serial number corresponding to different drugs, and its value is ; The total amount of medication used in the current cycle.

3. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 2 is characterized in that: Calculate the balance index The method is: Physiological function data also includes the patient's actual heart rate value , basic heart rate value , maximum heart rate ,height and weight ; Nutritional data including maximum metabolic equivalents , energy intake value , serum albumin content and ideal body mass index ; According to the patient's actual heart rate , basic heart rate value , maximum heart rate , maximum metabolic equivalent and energy intake Calculate actual metabolic equivalents , the formula based on is: According to the patient's height ,weight , serum albumin content and ideal body mass index Calculating nutrient reserves , the formula based on is: in, Serum albumin content The weight coefficient is between 0.4 and 0.6; is the weight coefficient of physical fitness index, ranging from 0.4 to 0.6; and 1; According to the actual metabolic equivalent and nutritional reserve value Calculate the balance index , the formula based on is: 。 4. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 3 is characterized in that: Calculation of wound inflammatory immune response index The method is: Wound data including initial wound area , initial wound depth , wound area at this time The depth of the wound , wound edge score and wound redness and swelling score ; Calculate wound data indicators based on wound data , the formula based on is: Immune function data include at least inflammatory factor concentrations and immune cell infiltration scores ; Calculate immune function indicators based on immune function data , the formula based on is: in, For the The concentration of inflammatory factors, is the serial number corresponding to different inflammatory factors, and its value is ; is the total amount of inflammatory factors; For the The infiltration degree of immune cells was scored. is the serial number corresponding to different immune cells, and its value is ; is the total number of immune cells; According to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index , the formula based on is: in, Wound data indicator The weight coefficient is between 0.3 and 0.7; Scoring immune function The weight coefficient is between 0.3 and 0.7; and 1.

5. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 4 is characterized in that: Calculation of pain tolerance and psychological resilience correlation index The method is: Pain data including pain tolerance score ; Psychological status data including psychological status scores ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data , the formula based on is: in, For the The patients' pain tolerance scores at the second observation were For different observation times, the value is ; is the total number of observations, which is a positive integer; For the The patient's mental status score at the second observation.

6. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 5, characterized in that: Calculation of immune defense response indexes The method is: Immune function data also includes neutrophil chemotaxis function score , the number of macrophages engulfing the target Total number of macrophages , serum concentration , lower limit of normal serum concentration and upper limit of normal serum concentration ; Calculate immune defense response index based on immune function data , the formula based on is: in, For the Neutrophil chemotaxis function score at the first observation; For the The number of macrophages engulfing the target during the first observation; For the The total number of macrophages at the time of observation; For the Serum concentrations of patients during the observation period.

7. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 6, characterized in that: Calculate body temperature and immune response index The method is: Physiological function data also includes patient temperature and average body temperature ; According to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index , the formula based on is: in, For the The patient's temperature at the time of the first observation.

8. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 7, characterized in that: Calculate postoperative care status value The method is: According to the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value , the formula based on is: 。 9. The intelligent monitoring and management method for postoperative care of tumor patients according to claim 8, characterized in that: Determine the management method according to different user's physical conditions, specifically: The set of physical condition thresholds includes a good threshold and medium threshold ; According to the postoperative care status value The nursing status threshold set is used to determine the user's physical status based on the following criteria: When the user is in good physical condition, choose management method 1; When the user's physical condition is moderate, choose management method 2; When the user is in poor physical condition, choose management method three.

10. An intelligent monitoring and management system for postoperative care of tumor patients, characterized in that: include: A data collection module is used to collect the patient's physiological function data, drug data, nutrition data, wound data, immune function data, pain data and psychological state data; Index calculation module, which can calculate stability index based on physiological function data and drug data ; Calculate actual metabolic equivalents based on physiological function data and nutritional data and nutritional reserve value , and further calculate the balance index ; Calculate wound data indicators based on wound data , calculate immune function index based on immune function data , according to wound data indicators and immune function indicators Calculation of wound inflammatory immune response index ; Calculate the correlation index between pain tolerance and psychological resilience based on pain data and psychological state data ; Calculate immune defense response index based on immune function data , according to the patient's temperature , average body temperature and immune defense response indicators Calculate body temperature and immune response index ; The judgment module can be based on the stability index , Balance Index , wound inflammatory immune response index , pain tolerance and psychological resilience correlation index and body temperature and immune response index Calculate postoperative care status value ; Preset physical state threshold set; according to the nursing state value The user's physical condition is judged by the set of nursing status thresholds, and the management method is determined according to different user physical conditions.

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