Holding device for a storage container of a needleless injector and needleless injector

Abstract

The present application provides a holding device for a storage container of a needleless injector, which can be switched between a locked state and an unlocked state, in the locked state, the holding device can prevent the storage container from being mounted to or removed from an injector body of the needleless injector; in the unlocked state, the holding device can allow the storage container to be mounted to or removed from the injector body, the holding device comprises: an operable part operated by an operator to switch the locked state and the unlocked state; a linkage mechanism switched between a first state and a second state in response to the operation of the operable part. The needleless injector comprising the holding device is also provided. According to the holding device and the needleless injector of the present application, the built-in medicine storage bottle can be freely mounted and taken out in the injector, and the built-in medicine storage bottle can be easily taken out or placed without using a separate tool, which provides convenience for the operator to use the needleless injector.

Description

Technical Field

[0001] This invention relates to medical devices for injecting substances, particularly needle-free injectors for injecting liquid medicines. More specifically, this invention relates to a holding device for a storage container of a needle-free injector and a needle-free injector. Background Technology

[0002] In medical settings, using a needle-free injector typically involves first attaching the tubing containing the medication to the injector body. The medication is then drawn from a separately placed reservoir through the distal end of the tubing. After drawing, the distal end of the tubing must be separated from the reservoir before injection. This type of injector has a complex operating procedure and requires a high level of skill. It is usually operated by medical professionals and is not suitable for home use by the general public.

[0003] To address this issue, the existing solution involves improving the syringe structure and replacing the traditional external reservoir with an internal one, allowing it to be housed within the syringe body. During operation, the medication is first drawn in through the movement of a piston rod within the tubing. The medication is then drawn from the reservoir within the syringe body through the proximal end of the tubing into the receiving cavity, completing the injection process.

[0004] However, this type of built-in reservoir can usually only be installed into or removed from the syringe body along with the injection head, including the tubing and piston rod. When it is necessary to replace the reservoir, it is difficult for the operator to flexibly and independently handle the reservoir, making it difficult to change the medication.

[0005] Therefore, there is a need to provide a holding device for the drug reservoir of a needle-free injector to improve existing needle-free injectors, so that the drug reservoir can be freely installed and removed therein, thereby at least partially solving the above-mentioned problems of existing needle-free injectors. Summary of the Invention

[0006] To overcome the aforementioned drawbacks of the prior art and facilitate the free replacement of the built-in reservoir in a needle-free injector, according to one aspect of the present invention, a retaining device for a storage container of a needle-free injector is provided. The storage container can be removably installed in the needle-free injector. The retaining device is configured to switch between a locked state and an unlocked state. In the locked state, the retaining device prevents the storage container from being installed into or removed from the syringe body of the needle-free injector. In the unlocked state, the retaining device allows the storage container to be installed into or removed from the syringe body. The retaining device includes: an operable component that is operable... The component can be operated by an operator to move between a locked position and an unlocked position of the operable component to switch the holding device between a locked state and an unlocked state; the linkage mechanism is configured to switch between a first state and a second state in response to the movement of the operable component between the locked position and the unlocked position, wherein when the operable component is in the locked position, the linkage mechanism is in the first state to prevent the storage container from being installed into or removed from the syringe body, and wherein when the operable component is in the unlocked position, the linkage mechanism is in the second state to allow the storage container to be installed into or removed from the syringe body.

[0007] In some preferred embodiments, the linkage mechanism is held by a tubular first internal push rod within the outer housing of the syringe body, wherein the storage container can be accommodated inside the first internal push rod.

[0008] In some preferred embodiments, the linkage mechanism includes: a limiting mechanism configured to move between a first position and a second position in response to movement of the operable component between a locked position and an unlocked position; and a blocking mechanism configured to switch between a blocking state and a non-blocking state in response to movement of the limiting mechanism between the first and second positions, wherein when the limiting mechanism is in the first position, the blocking mechanism is in a blocking state, and the blocking mechanism in the blocking state can interfere with the storage container in the radial direction to prevent the storage container from being installed into or removed from the syringe body, and wherein when the limiting mechanism is in the second position, the blocking mechanism is in a non-blocking state, and the blocking mechanism in the non-blocking state does not interfere with the storage container to allow the storage container to be installed into or removed from the syringe body.

[0009] In some preferred embodiments, the operable component is arranged on the outer housing and is configured as a press-operable component.

[0010] In some preferred embodiments, the operable component is arranged on the outer housing and is configured as a push-operable component.

[0011] In some preferred embodiments, the limiting mechanism is configured to respond to axial movement of the operable component between a locked position and an unlocked position, and axial movement between a first position and a second position.

[0012] In some preferred embodiments, the operable component can be mounted in a recess in the circumferential sidewall of the outer housing of the syringe body, and the operable component can move in the recess relative to the outer housing in the axial direction between a locked position and an unlocked position.

[0013] In some preferred embodiments, the operable component includes: a base extending in an axial direction; an operator engagement portion configured to extend radially outward from a radially outer surface of the base and capable of being engaged by an operator to operate the operable component to move between a locked position and an unlocked position; a sliding portion configured to extend radially inward from a radially inner surface of the base and capable of contacting a radially outer surface of the bottom wall of a recess of the outer housing for axial movement on that surface; and a protrusion configured to extend radially inward from the radially inner surface of the sliding portion and protrude radially inward from an opening at a corresponding location on the bottom wall of the recess toward the radially inner side of the outer housing, the opening extending in an axial direction and allowing axial movement therein, wherein the protrusion is capable of engaging a linkage mechanism such that the linkage mechanism switches between a first state and a second state in response to axial movement of the protrusion in the opening of the recess.

[0014] In some preferred embodiments, the sliding portion of the operable component includes a columnar member extending in the axial direction, and the end wall of the recess perpendicular to the axial direction has a hole aligned with the columnar member. The retaining device further includes a first spring extending in the axial direction, the first spring including: a first end portion received and confined within the hole in the end wall of the recess; and a second end portion sleeved on the outer periphery of the columnar member. The first spring is configured to bias the operable component toward a locked position via the columnar member.

[0015] In some preferred embodiments, the locked position of the operable component is positioned distally relative to the unlocked position, wherein the columnar component extends proximally from the proximal end surface of the sliding portion, the hole is formed in the proximal end wall of the recess, and wherein the first spring is configured to bias the operable component toward the distal locked position via the columnar component.

[0016] In some preferred embodiments, the retaining device further includes a first guide engagement portion extending in an axial direction disposed in a recess of the outer housing, wherein the sliding portion of the operable component includes a second guide engagement portion extending in an axial direction, and wherein the first guide engagement portion and the second guide engagement portion are configured to cooperate with each other to guide the movement of the sliding portion of the operable component in the recess of the outer housing.

[0017] In some preferred embodiments, the first guide engagement is configured to include at least one guide post fixedly disposed in a recess of the outer housing, and the second guide engagement is configured to include at least one through hole extending axially through the sliding portion, each through hole being shaped to fit a corresponding guide post, thereby allowing the sliding portion to move axially through the axial movement of the corresponding guide post via each through hole.

[0018] In some preferred embodiments, the two ends of each guide post in the axial direction are respectively received and fixed in two U-shaped fasteners extending radially outward from the radially outer surface of the bottom wall of the recess, the two U-shaped fasteners being configured to jointly restrict the movement of the guide post.

[0019] In some preferred embodiments, the sliding part has two through holes, which are respectively opened at two ends of the sliding part parallel to the axial direction. Correspondingly, the sliding part has two guide posts, which are respectively located on the recessed part at positions corresponding to the circumferential positions of the two through holes of the sliding part.

[0020] In some preferred embodiments, the blocking mechanism includes a first annular component, which includes a blocking portion having a through hole extending radially, the through hole accommodating a ball, wherein the diameter of the through hole is not less than that of the ball to allow the ball to move back and forth radially along the inner wall surface of the through hole, and wherein the through hole includes: a first opening end located radially inward, a second opening end located radially outward, and an annular first flange extending from the inner wall surface of the through hole into the through hole at the first opening end, the first flange being sized to allow at least a portion of the ball to protrude radially inward from the first opening end of the through hole, while preventing the ball from continuing to move radially inward and detaching from the through hole.

[0021] In some preferred embodiments, the limiting mechanism includes a second annular member sleeved on the outer periphery of the first annular member. The second annular member is configured to move axially between a first position and a second position in response to axial movement of the protrusion in the opening of the recess in the outer housing. The second annular member includes an annular second flange extending radially inward from the inner wall surface of the second annular member. When the second annular member is in the first position, the second flange is axially aligned with the through-hole of the blocking mechanism, and the radially inward surface of the second flange abuts against a ball in the through-hole of the blocking mechanism, forcing at least a portion of the ball to protrude radially inward from the first opening end of the through-hole, thereby interfering with the storage container in the radial direction. When the second annular member is in the second position, the second flange is axially misaligned with the through-hole of the blocking mechanism, allowing the ball to move freely radially outward to a position where it no longer protrudes radially inward from the first opening end of the through-hole, thereby no longer interfering with the storage container.

[0022] In some preferred embodiments, the proximal end of the first annular member is configured to be secured to the distal end of the first internal push rod.

[0023] In some preferred embodiments, the first position is located distally relative to the second position, wherein the limiting mechanism further includes a second spring positioned between the first annular member and the second annular member and sleeved on the outer periphery of the first annular member, wherein the proximal end of the second spring abuts against the distal end surface of the first inner push rod, and the distal end of the second spring abuts against the proximal surface of the second flange of the second annular member, and wherein the second spring is configured to bias the second annular member toward the distal first position via the proximal end surface of the second flange.

[0024] In some preferred embodiments, the proximal end of the first annular component is formed with an external thread, and the distal end of the first internal push rod is formed with an internal thread that engages with the external thread of the first annular component.

[0025] In some preferred embodiments, a chamfer is formed on the distal side of the second flange of the second annular member, wherein, as the second annular member moves axially from the first position toward the proximal side to the second position, the ball can move along the chamfer of the second flange to a position where it no longer protrudes radially inward from the first opening end of the through hole.

[0026] In some preferred embodiments, the second annular member further includes a third flange located at the distal portion of the second annular member and extending radially inward from the inner wall of the second annular member, wherein the second flange is located proximal to the third flange and forms a first annular groove between the second and third flanges, the first annular groove being configured to at least partially accommodate a ball when the second annular member is in the second position.

[0027] In some preferred embodiments, the first annular component includes a plurality of circumferentially distributed through holes, each of which contains a ball.

[0028] In some preferred embodiments, multiple through holes are arranged at equal intervals.

[0029] In some preferred embodiments, the holding device further includes a base for holding the storage container, the base being located proximal to the storage container and configured to conform to the shape of the proximal end of the storage container for receiving and holding the proximal end of the storage container.

[0030] In some preferred embodiments, the retaining device further includes a third spring configured to be positioned between the base and a tubular second internal push rod within the outer housing of the syringe body. The second internal push rod is configured to be located proximal to the first internal push rod and fixed to it. The third spring is configured to bias the base distally in an axial direction.

[0031] In some preferred embodiments, the second internal push rod includes: a first axial extension including an elongated first through groove extending in an axial direction on a sidewall, the first through groove extending to a distal end of the first axial extension; and a second axial extension extending distally from the distal end of the first axial extension, wherein an annular fourth flange extending radially inward from an inner wall surface of the first axial extension is provided at approximately the midpoint of the axial direction of the first axial extension, and wherein the second axial extension is used to engage a proximal end of the first internal push rod to fix it to the first internal push rod.

[0032] In some preferred embodiments, the base includes: a third axial extension, the distal portion of which is provided with a protrusion extending distally, the protrusion corresponding to a first through groove of the second internal push rod, thereby enabling it to move axially within the first through groove; and a fourth axial extension extending distally from the distal end of the third axial extension.

[0033] In some preferred embodiments, the proximal end of the third spring abuts against the distal surface of the fourth flange of the second inner push rod, and the distal end of the third spring abuts against the internal step surface of the connection region between the third axial extension and the fourth axial extension of the base, which extends perpendicularly to the axial direction, thereby enabling the base to be biased distally in the axial direction by the internal step surface.

[0034] In some preferred embodiments, the storage container includes a distal drug storage area and an annular engagement area extending proximally from the proximal end of the drug storage area. The engagement area is held between a tab and a fourth axial extension of the base, and wherein the proximal end of the engagement area abuts against an external stepped surface perpendicular to the axial direction of the connection area between the third and fourth axial extensions of the base, such that when an operator operates to unlock the holding device, the storage container can be pushed out of the syringe body by a third spring along with the base.

[0035] In some preferred embodiments, the second axial extension of the second internal push rod is provided with an internal thread, and the proximal end of the first internal push rod is provided with an external thread that engages with the internal thread of the second axial extension.

[0036] In some preferred embodiments, the first axial extension of the second internal push rod includes a plurality of first through slots, and the third axial extension of the base includes a plurality of tabs corresponding to the positions of the first through slots and in the same number.

[0037] In some preferred embodiments, the inner wall surface of the proximal end of the first internal push rod is provided with a second annular groove, in which a rubber ring is accommodated to contact the outer peripheral surface of the storage container, the rubber ring being used to prevent the storage container from moving.

[0038] In some preferred embodiments, the first annular component further includes an engagement portion located distal to the blocking portion, the engagement portion being used to engage the piston rod of the injection head to fix it to itself.

[0039] In some preferred embodiments, the engagement portion of the first annular component is formed with a third annular groove near the distal end of the first annular component, and wherein the proximal end of the piston rod is provided with an elastic snap-fit ​​portion extending proximally in the axial direction, the snap-fit ​​portion being snapped onto the distal end face of the third annular groove, thereby fixing the piston rod and the first annular component to each other.

[0040] In some preferred embodiments, the limiting mechanism includes a slip ring component disposed in a first internal push rod and sleeved on the storage container. The slip ring component is responsive to axial movement of an operable component between a locked position and an unlocked position, and axial movement relative to the storage container between the first and second positions. The slip ring component includes: a distal cylindrical portion with a protrusion arranged on its outer peripheral sidewall, the protrusion engaging the operable component to move axially within a corresponding groove on the inner wall surface of the first internal push rod under the actuation of the operable component, thereby guiding the axial movement of the slip ring component; and a proximal truncated conical portion for engaging a blocking mechanism to switch the blocking mechanism between a blocking state and a non-blocking state.

[0041] In some preferred embodiments, the blocking mechanism is positioned proximal to the limiting mechanism and includes: an elastic ring member disposed in the first internal push rod and sleeved on the storage container, the elastic ring member being capable of engaging the truncated conical portion of the distal slip ring member; and a mounting member for fixing the elastic ring member to the first internal push rod, the mounting member including a distal tubular element and a proximal annular limiting element, wherein the tubular element is engaged in a corresponding fixing groove in the first internal push rod and is fixedly connected to the elastic ring member, and wherein the annular limiting element is disposed adjacent to the proximal side of the tubular element for limiting the axial movement of the tubular element.

[0042] In some preferred embodiments, the elastic annular component includes a plurality of elastic elements arranged continuously in a circumferential direction, each elastic element including: a fixed portion located radially outward for fixing the elastic element to the distal edge of the tubular component; and a deformable portion capable of elastically deforming such that the included angle between the deformable portion and the fixed portion switches between a first angle and a second angle.

[0043] In some preferred embodiments, when the slip ring component of the limiting mechanism is in the first position on the far side, the truncated conical portion does not engage the annular component, and the angle between the deformable portion and the fixed portion of each of the plurality of elastic elements is a first angle. At this time, the radially inner end of the deformable portion contacts and interferes with the storage container. When the slip ring component of the limiting mechanism moves to the second position on the near side, the truncated conical portion biases the deformable portion of each of the plurality of elastic elements radially outward, so that the angle between the deformable portion and the fixed portion of each of the plurality of elastic elements changes from the first angle to the second angle. At this time, the radially inner end of the deformable portion does not contact the storage container, and wherein the first angle is greater than the second angle.

[0044] In some preferred embodiments, the radially inner ends of the deformable portions of a plurality of elastic elements collectively form an opening of an elastic annular component, wherein the opening has a first diameter when the angle between the deformable portion and the fixed portion of each of the plurality of elastic elements is a first angle; wherein the opening has a second diameter when the angle between the deformable portion and the fixed portion of each of the plurality of elastic elements is a second angle, and wherein the second diameter is greater than the first diameter.

[0045] In some preferred embodiments, the bump includes a hole configured to be engaged by an operating lever of an operable component.

[0046] In some preferred embodiments, a second through groove is provided on the first internal push rod at a position corresponding to the protrusion, which allows the hole of the protrusion to be exposed to the operating rod when the slip ring component moves between the first position and the second position.

[0047] In some preferred embodiments, the cylindrical portion of the slip ring component includes two symmetrically arranged protrusions, and correspondingly, the first internal push rod includes two symmetrically arranged second through slots.

[0048] In some preferred embodiments, the operable component is arranged on the outer housing and is configured as a press-operable component, and the linkage mechanism includes a rocker arm and an elastic element housed within and held by a first internal push rod.

[0049] In some preferred embodiments, a through slot is provided on the circumferential sidewall of the first internal push rod near the distal end for receiving and holding the rocker arm and the elastic element, wherein the rocker arm is pivotally mounted to the through slot.

[0050] In some preferred embodiments, the rocker arm includes a pin located approximately at the center of the rocker arm, the rocker arm being mounted to a through slot via the pin, wherein the through slot includes two opposing sidewalls extending in an axial direction, each sidewall having a mounting hole formed therein for receiving and securing the end of the pin, and wherein the rocker arm is pivotable about the pin in the through slot.

[0051] In some preferred embodiments, the lever includes a first leg located proximal to the pin and a second leg located distal to the pin, wherein one of the first and second legs is capable of switching from a first state of radially interfering with the storage container to a second state of not interfering with the storage container in response to the operable component being pressed by an operator to move from a locked position toward an unlocked position.

[0052] In some preferred embodiments, the second leg of the lever is capable of switching from a first state of radially interfering with the storage container to a second state of not interfering with the storage container in response to the operation of the operable component being pressed by an operator to move from a locked position to an unlocked position, and wherein the second leg of the lever includes a protrusion extending radially inward from the radially inner surface of the second leg, the protrusion being configured to radially interfere with the storage container when the second leg of the lever is in the first state, and to not interfere with the storage container when the second leg is in the second state.

[0053] In some preferred embodiments, the elastic element is configured to bias the second leg of the lever toward a first state that radially interferes with the storage container.

[0054] In some preferred embodiments, the through slot of the first internal push rod for receiving and holding the swing arm is a third through slot, the third through slot including a first portion on the proximal side and a second portion on the distal side with a width smaller than the first portion, wherein an elastic element is arranged between the radially outer surface of the second leg of the swing arm and the radially inner surface of the circumferential sidewall of the first internal push rod located at the second portion of the third through slot, and is capable of biasing the second leg of the swing arm in the radially inner direction toward the position of radially interfering with the storage container.

[0055] In some preferred embodiments, the operable component is capable of engaging the first leg of the lever to allow the first leg of the lever to move radially inward when the operator presses the operable component, such that the lever overcomes the biasing force of the elastic element and pivots about the pin to the protrusion of the second leg of the lever without interfering with the position of the storage container.

[0056] In some preferred embodiments, the second portion of the third channel includes a bottom wall configured such that when the second leg of the rocker arm is in the first state, the distal end of the second leg can overlap the bottom wall, wherein the bottom wall does not contact the protrusion of the rocker arm.

[0057] In some preferred embodiments, the first and second legs of the pendulum extend substantially parallel to each other.

[0058] In some preferred embodiments, the first leg of the lever is capable of switching from a first state of radially interfering with the storage container to a second state of not interfering with the storage container in response to the movement of the operable component from a locked position to an unlocked position by being pressed by an operator, and wherein the proximal end of the first leg of the lever is configured to radially interfere with the storage container when the first leg of the lever is in the first state, and to not interfere with the storage container when the first leg is in the second state.

[0059] In some preferred embodiments, the elastic element is configured to bias the second leg of the lever toward the radially outward direction, such that the lever pivoting about the pin at the proximal end of the first leg of the lever can radially interfere with the position of the storage container.

[0060] In some preferred embodiments, the through-slot of the first internal push rod for receiving and holding the swing arm is a fourth through-slot, the fourth through-slot including a first portion on the proximal side and a second portion on the distal side, wherein the first portion of the fourth through-slot allows the first leg of the swing arm to pass through therethrough and radially interfere with the storage container, and wherein the second portion of the fourth through-slot is provided with a bottom wall, and an elastic element is held between the bottom wall and the radially inner surface of the second leg of the swing arm.

[0061] In some preferred embodiments, the operable component can engage the second leg of the lever such that when the operator presses the operable component, the second leg of the lever can overcome the biasing force of the elastic element and move radially inward, so that the lever pivots about the pin to the proximal end of the first leg of the lever without interfering with the position of the storage container.

[0062] In some preferred embodiments, an obtuse angle is formed between the first leg and the second leg of the lever in a radially inward direction.

[0063] In some preferred embodiments, one or more through slots are provided in the circumferential sidewall of the first internal push rod, each through slot accommodating and retaining the rocker arm and the elastic element.

[0064] In some preferred embodiments, the elastic element is a tension spring.

[0065] In some preferred embodiments, the operable component is arranged on the outer housing and is configured as a press-operated component, wherein the limiting mechanism is configured to move in a vertical radial direction between a locked position and an unlocked position, and between an upper first position and a lower second position, in response to movement of the operable component in a vertical radial direction, and wherein the blocking mechanism is configured to switch between a closed blocking state and an open non-blocking state in response to movement of the limiting mechanism between the first and second positions.

[0066] In some preferred embodiments, the limiting mechanism includes a retaining ring that can be engaged by an operable component such that the retaining ring moves downward when the operator presses down on the operable component.

[0067] In some preferred embodiments, the retaining ring can be fitted over the storage container on the radially outer side of the storage container, wherein the retaining ring includes a top that can be engaged by an operable component and two generally arc-shaped arms extending from the top toward both sides, each of the two arms having a guide groove at its end away from the top for engaging a blocking mechanism and guiding the movement of the blocking mechanism, and wherein the guide groove extends in a horizontal radial direction.

[0068] In some preferred embodiments, the first internal push rod is formed with a groove for receiving a retaining ring, the groove matching the shape of the retaining ring such that the retaining ring can move in the groove in a vertical radial direction between a first position and a second position, wherein the groove includes two guide portions extending in the vertical radial direction, each guide portion receiving one of the two ends of the two arms of the retaining ring away from the top, and allowing that end to move up and down in the vertical radial direction therein.

[0069] In some preferred embodiments, the slot of the first internal push rod includes a first tongue extending distally from a proximal surface of the slot in a direction perpendicular to the axial direction, the first tongue being located directly below the top of the retaining ring.

[0070] In some preferred embodiments, the limiting mechanism further includes an elastic element that abuts between a hole in the bottom surface of the top of the retaining ring and the top surface of the first tongue, and is configured to bias the retaining ring upward.

[0071] In some preferred embodiments, the blocking mechanism includes two swing arms that are generally arc-shaped, each swing arm being pivotally connected to a first internal push rod via its underside end.

[0072] In some preferred embodiments, a guide pin is provided at approximately the middle position of each swing arm, which is movable along a guide groove on the same side of the arm of the retaining ring. When the retaining ring is in the upper first position, each guide pin is located at the radially inner end of the corresponding guide groove, so that the two swing arms together form a closed blocking state. In the blocking state, the two swing arms radially interfere with the storage container. And when the operator presses the operable component to move the retaining ring downward to the second position, the retaining ring drives the corresponding guide pin to move to the radially outer end of the guide groove through each guide groove, so that the two swing arms move radially outward to form an open non-blocking state. In the non-blocking state, the two swing arms do not interfere with the storage container.

[0073] In some preferred embodiments, the retaining device further includes an annular limiting element for limiting the axial position of the blocking mechanism and the limiting mechanism.

[0074] In some preferred embodiments, the limiting element is located distal to the blocking mechanism and the limiting mechanism to prevent the blocking mechanism and the limiting mechanism from moving distally away from the first internal push rod.

[0075] In some preferred embodiments, the blocking mechanism is located distal to the limiting mechanism, and the limiting element includes: an annular flange extending proximally, capable of abutting the two swing arms distally; and a second tongue extending proximally beyond the annular flange, capable of abutting the top of the retaining ring distally when the retaining ring is in the first position above.

[0076] According to another aspect of the present invention, a needleless injector is provided, comprising an injector body and a storage container located within an outer housing of the injector body, the storage container being removably mounted in the needleless injector, wherein the injector body comprises: an outer housing and a tubular first internal push rod within the outer housing, characterized in that the needleless injector further comprises: a retaining device for the storage container according to any one of the foregoing embodiments, the retaining device being configured to prevent the storage container from being mounted into or removed from the needleless injector in a locked state, or to allow the storage container to be mounted into or removed from the needleless injector.

[0077] In some preferred embodiments, the needleless injector also includes an injection head that can be removably mounted to the injector body, the distal end of the injection head including an injection micropore.

[0078] In some preferred embodiments, the storage container is a cartridge bottle.

[0079] In some preferred embodiments, the linkage mechanism is held by a tubular first internal push rod within the outer housing of the syringe body, and the storage container can be accommodated inside the first internal push rod, wherein the first internal push rod includes a first cutout formed on the circumferential sidewall, and the outer housing includes a second cutout aligned with the first cutout in the circumferential direction, the first cutout and the second cutout together forming a viewing window for the operator to observe the storage container.

[0080] In some preferred embodiments, the operable component can be mounted in a recess on the circumferential sidewall of the outer housing of the syringe body, and the first and second hollow portions have elongated shapes extending in the axial direction, wherein the second hollow portion is located near the recess.

[0081] In some preferred embodiments, the needleless injector further includes a cap that engages with the outer housing of the needleless injector to cover the recess and the second cutout, and wherein the cap includes a window through which the operator engagement portion of the operable components can be exposed to the operator when the cap is closed on the outer housing.

[0082] With the retaining device and needleless injector according to the present invention, the built-in drug reservoir can be freely installed and removed from the injector without the need for a separate tool, which provides convenience for the operator to use the needleless injector. Attached Figure Description

[0083] To better understand the above and other objects, features, advantages, and functions of the present invention, reference can be made to the preferred embodiments shown in the accompanying drawings. The same or similar reference numerals in the drawings refer to the same or similar parts. Those skilled in the art should understand that the drawings are intended to schematically illustrate preferred embodiments of the invention and do not limit the scope of the invention in any way; the parts in the drawings are not drawn to scale.

[0084] Figure 1 A perspective view of a needleless injector according to a preferred embodiment of the present invention is shown.

[0085] Figure 2 It shows Figure 1 An exploded view of the needle-free injector shown.

[0086] Figure 3 It shows Figure 1 An exploded view of the injection head and related components of the needleless injector shown.

[0087] Figures 4 to 6 It shows Figure 1 A perspective view of the components inside the outer casing of the needle-free injector shown.

[0088] Figure 7 It shows Figure 1 The diagram shows the fit between the outer shell and the cap of the needle-free injector.

[0089] Figures 8 to 9 It shows Figure 1 A schematic diagram of the distal portion of the outer housing of the needleless injector shown, illustrating a recess in the outer housing that mates with the cap.

[0090] Figure 10 A preferred embodiment of the invention is shown for use Figure 1 A perspective view of the operable components of the holding device of the needleless injector shown.

[0091] Figure 11 A preferred embodiment of the invention is shown for use Figure 1 A perspective view of the linkage mechanism of the holding device of the needleless injector shown.

[0092] Figures 12 to 13 It shows Figure 11 A perspective view of the blocking mechanism of the linkage mechanism shown.

[0093] Figure 14 It shows Figure 11 A three-dimensional view of the limiting mechanism of the linkage mechanism shown.

[0094] Figures 15A to 15B They are shown respectively Figure 11 The diagram shows the linkage mechanism in its first and second states.

[0095] Figures 16A to 16B They are shown respectively Figures 15A to 15B A magnified view of a portion of the linkage mechanism.

[0096] Figure 17 A perspective view of the second internal push rod according to a preferred embodiment of the present invention is shown.

[0097] Figure 18 A perspective view of the base of a storage container according to a preferred embodiment of the present invention is shown.

[0098] Figure 19 A perspective view of the base of a storage container according to a preferred embodiment of the present invention is shown from another direction.

[0099] Figures 20 to 22 A schematic diagram of a holding device according to another preferred embodiment of the present invention is shown.

[0100] Figures 23 to 25 A schematic diagram of a holding device according to yet another preferred embodiment of the present invention is shown.

[0101] Figures 23 to 25 A schematic diagram of a holding device according to yet another preferred embodiment of the present invention is shown.

[0102] Figures 26 to 29 A schematic diagram of a holding device according to yet another preferred embodiment of the present invention is shown.

[0103] Figures 30 to 36 A schematic diagram of a holding device according to yet another preferred embodiment of the present invention is shown. Detailed Implementation

[0104] The following will describe in detail, with reference to the accompanying drawings, a holding device for a storage container and a needleless injector, the needleless injector being provided with the holding device. The embodiments given below are merely preferred embodiments of the invention; those skilled in the art can conceive of other ways to implement the invention based on the preferred embodiments, and such other ways also fall within the scope of the invention.

[0105] The present invention provides a retaining device for a storage container that can be removably mounted in and used with a needle-free injector. The retaining device is configured to switch between a locked state and an unlocked state, wherein in the locked state, the retaining device prevents the storage container from being mounted to or removed from the injector body; and in the unlocked state, the retaining device allows the storage container to be mounted to or removed from the injector body.

[0106] To better describe the holding device according to the invention and for ease of understanding, the overall structure of the needleless syringe will be introduced first.

[0107] First, it should be noted that the directional and positional terms mentioned in this invention should be understood as relative directions and relative positions. The directional and positional terms mentioned in this invention can be understood with reference to the accompanying drawings. For example, "axial direction" and "axial direction (X)" mentioned in this invention can be understood as directions parallel or approximately parallel to the longitudinal central axis of the syringe, that is, directions along or parallel to the XX direction in the accompanying drawings; "radial direction," "radial direction," "up," "down," "circumferential direction," and "circumferential direction" mentioned in this invention are all directions defined with respect to the XX axis. For example, the radial outer direction indicates a direction away from the longitudinal central axis of the syringe, the radial inner direction indicates a direction towards the longitudinal central axis of the syringe, up-down movement refers to back-and-forth movement along a specific radial direction, and the circumferential direction indicates a direction around the longitudinal central axis of the syringe; the "rotational direction" mentioned in this invention can be understood as a direction of rotation around the XX axis, which is approximately equivalent to the "circumferential direction." The terms "near," "proximal," "proximal end," "proximal direction," "posterior," "posterior side," "rear end," and "posterior direction" mentioned in this invention refer to directions close to the operator's hand along the axis XX or parallel to the axis XX (considering the operator holding the syringe to draw and inject the drug); the terms "distal," "distal end," "distal direction," "anterior," "anterior side," "front end," and "anterior direction" mentioned in this invention refer to directions away from the operator's hand along the axis XX or parallel to the axis XX, and are also the direction in which the injected substance is ejected during the injection step.

[0108] Overall structure

[0109] Figure 1 An overall perspective view of a needle-free injector according to some preferred embodiments of the present invention is shown. Figure 2 It shows Figure 1An exploded view of the syringe. The syringe in this embodiment is a needle-free syringe. Unlike traditional needle-based syringes, needle-free syringes do not inject through a needle. Instead, a micro-orifice is provided at the distal end of the injection head. During injection, the substance to be injected is rapidly ejected through this micro-orifice and injected into the patient's body. It should be noted that this article uses pharmaceuticals, liquid medications, and other injectable substances as examples to describe the concept of the invention, but this is merely an example and not restrictive. The substance to be injected can be of various other types, such as saline solution, glucose, solid microparticles, etc. Any substance that can be injected into the human body by the needle-free syringe of this invention falls within the protection scope of this invention. This invention does not limit the form and type of the substance to be injected.

[0110] refer to Figures 1 to 6 According to this preferred embodiment, the syringe 1 includes the following components: an injection head 2, a syringe body 3, and a storage container 4. Each component can be packaged separately before use and then assembled together for use.

[0111] The injection head 2 includes: a drug tube 21 for containing the liquid medicine to be injected drawn from the storage container 4; an end cap 23 removably engaging with the distal portion of the drug tube to keep the drug tube sealed during the aspiration process described below, thereby sealing the injection micro-orifice at the distal end of the drug tube, and being removed during injection to expose the injection micro-orifice; and a piston rod 22 movable within the drug tube 21 in an axial direction X relative to the drug tube 21 to draw the liquid medicine from the storage container 4 into the drug tube during aspiration, and to eject the liquid medicine to be injected from the drug tube 21 through the injection micro-orifice during injection, thereby spraying the liquid medicine through the micro-orifice to complete the injection. The storage container 4 can be a container for storing medicines, such as a cartridge bottle according to national standards. According to the invention, the storage container 4 is built-in and can be removably installed into the syringe 1 (specifically, into the syringe body 3) for use with the syringe body 3 and the injection head 2.

[0112] The syringe body 3 includes an outer shell 32, a rear shell 31, a first internal plunger 33, and a second internal plunger 34. The outer shell 31 houses various components within the syringe body and has an external thread at its proximal end for engagement with an internal thread at the distal end of the rear shell 31. This allows the operator to rotate either the rear shell 31 or the outer shell 32 to achieve axial relative movement between them. (Reference) Figure 2 , Figure 4 and Figure 5The outer housing 32 houses a first internal push rod 33 and a second internal push rod 34 located near the first internal push rod. The first internal push rod 33 is used to accommodate the storage container 4 to carry the storage container and drive its movement during operation. The two internal push rods 33 and 34 are fixed to each other (e.g., by threaded engagement) and can be locked or unlocked with the rear housing 31 by engaging a locking member (not shown) located near the second internal push rod 34 with a locking mechanism 35 (which is fixedly mounted on the rear housing 31).

[0113] The injection head 2 can be removably attached to the syringe body 3. Specifically, refer to... Figure 2 and Figure 3 The drug tube 21 of the injection head 2 can be fixedly mounted to the outer housing 32, for example, by the engagement between the external thread of the proximal portion of the drug tube 21 and the internal thread of the outer housing 32 near the distal opening. Throughout the operation after fixed mounting, the drug tube 21 remains fixed to the outer housing 32; the movement of the drug tube 21 is driven by the outer housing 32, and there is no relative movement between them. The piston rod 22 of the injection head 2 can be fixedly mounted to the aforementioned first internal push rod 33 or to other components fixedly connected to the first internal push rod 33. For example, such as... Figure 3 As shown, the proximal end of the piston rod 22 may include a resilient latching portion 221 extending proximally in the axial direction X, which can engage with... Figure 13 The first annular component 5221 shown (the proximal end of which is fixed to the first internal push rod 33, which will be described in detail below) is fixed. During the entire operation after the fixed installation, the piston rod 22 remains fixed to the first annular component, and thus remains fixed relative to the first internal push rod 33. The piston rod 22 is driven by the first internal push rod 33 to move in the axial direction.

[0114] The operation process of the syringe according to the present invention after installation mainly includes the following steps: pressurization and energy storage step, drug intake step, air exhaust step, and injection step.

[0115] First, in the pressurization and energy storage step, initially, the actuation spring 39 located proximally between the outer housing 32 and the rear housing 31 is in an extended state, causing the outer housing 32 to be positioned distally relative to the rear housing 31. Upon initiation of pressurization and energy storage, the operator rotates the outer housing 32 proximally relative to the rear housing 31 (achieved through a threaded engagement). During this process, the distal portion of the outer housing 32 applies force to the distal portion of the first internal push rod 33 (e.g., the distal flange 33a), thereby simultaneously moving the first internal push rod 33 and the second internal push rod 34 proximally. When the outer housing 32 is threadedly tightened relative to the rear housing 31, a locking member (not shown) proximally to the second internal push rod 34 locks into place with the locking mechanism 35, thereby locking the first and second internal push rods 33 and 34 to the rear housing 31. During this process, the actuation spring 39 is compressed and stores energy in preparation for the final injection step.

[0116] Following the pressurization and energy storage step is the drug aspiration step. During this step, the operator rotates the outer housing 32 to move it distally relative to the rear housing 31 (still achieved through the threaded engagement between the two). At this time, the first and second internal push rods 33 and 34 are locked by the locking mechanism 35 and thus remain fixed relative to the rear housing 31. In other words, during this process, the outer housing 32 moves distally relative to the first and second internal push rods 33 and 34. Since the drug tube 21 is fixed relative to the outer housing 32, and the storage container 4 and piston rod 22 are fixed relative to the first internal push rod 33, the drug tube 21 moves distally relative to the storage container 4 and piston rod 22. Furthermore, since the injection micro-orifice at the distal end of the drug tube 21 is closed by the cap 23 (for example, the cap 23 is provided with a sealing gasket for sealing the injection micro-orifice when it is closed on the drug tube 21), when the drug tube 21 moves distally relative to the piston rod 22, the distal portion of the inner cavity of the drug tube 21 (i.e., the chamber located between the distal end of the piston rod and the distal end of the drug tube) forms a receiving cavity. The pressure in the receiving cavity is relatively low, so the liquid in the storage container 4 can be drawn into the receiving cavity 215 through the needle 24 contained in the drug liquid channel in the piston rod 22, thereby completing the drug aspiration.

[0117] Following the drug intake step is the venting step, a pre-injection preparation step designed to remove any gas that may have entered the drug delivery tube 21 before injection. In this step, the cap 23 is first removed, exposing the injection micro-orifice at the distal end of the drug delivery tube 21. Then, the outer housing 32 is rotated so that it moves slightly rearward relative to the rear housing 31. During this process, the locking mechanism 35 remains locked, keeping the first internal push rod 33 and the piston rod 22 fixed relative to the rear housing 31. Thus, the drug delivery tube 21 (fixed relative to the outer housing 32) moves slightly proximally relative to the piston rod 22 (fixed relative to the first internal push rod 33), and the piston rod 22 slightly compresses the receiving cavity within the drug delivery tube 21, allowing the gas within the cavity to be expelled from the injection micro-orifice under pressure.

[0118] Finally, the injection step. In this step, the outer housing 32 and the drug tube 21 are fixed relative to the rear housing 31. The operator operates the locking mechanism 35 (e.g., presses the button 351 on the proximal end of the syringe) to release it from the locking state between it and the locking member (not shown) located near the first and second internal push rods. This allows the second internal push rod 34, the first internal push rod 33, the storage container 4, and the piston rod 22 to move rapidly distally relative to the rear housing 31 under the return action of the actuation spring 39, thereby completing the injection by rapidly squeezing the liquid in the receiving cavity of the drug tube 21 through the piston rod 22.

[0119] Holding device

[0120] For the syringe described above, after the injection step is completed, the operator can disassemble the syringe components for easy storage.

[0121] Typically, as described above, the built-in storage container 4 can only be installed into or removed from the syringe body 3 along with the injection head 2, including the tubing 21 and piston rod 22; the storage container 4 cannot be disassembled separately. When it is necessary to replace the storage container, the operator finds it difficult to flexibly and independently handle the storage bottle, causing inconvenience such as difficulty in changing medication.

[0122] To at least partially solve the above-mentioned problems, the present invention provides a retaining device 5 that facilitates the replacement of the storage container 4. This retaining device is configured to switch between a locked state and an unlocked state, wherein in the locked state, the retaining device prevents the storage container from being installed into or removed from the syringe body; and in the unlocked state, the retaining device allows the storage container to be installed into or removed from the syringe body. The retaining device 5 according to the present invention will be described in detail below.

[0123] First, it should be noted that the reference... Figures 5 to 6During the installation and removal of the storage container 4, as discussed below, the injection head 2 is not mounted on the syringe body 3, thus not obstructing the installation and removal of the storage container 4. For example, in the assembly step, the operator first switches the holding device 5 to the unlocked state, then inserts the storage container 4 into the first internal push rod 33 within the outer housing 32 proximally through the distal opening of the outer housing 32 and the distal opening of the first internal push rod 33, and then installs the injection head 2. In the removal step, the operator first removes the injection head 2 from the syringe body 3, thus no longer obstructing the distal opening of the outer housing 32 and the distal opening of the first internal push rod 33, then switches the holding device 5 to the unlocked state, and removes the storage container 4 from the first internal push rod 33 within the outer housing 32 distally through the distal opening of the outer housing 32 and the distal opening of the first internal push rod 33.

[0124] Next reference Figures 7 to 14 The retaining device 5 is described in detail below. The retaining device includes: an operable component 51 operable by an operator between a locked position and an unlocked position to switch the retaining device between a locked state and an unlocked state; and a linkage mechanism 52 configured to switch between a first state and a second state in response to movement of the operable component 51 between the locked and unlocked positions. When the operable component 51 is in the locked position, the linkage mechanism 52 is in a first state in which it prevents the storage container 4 from being installed into or removed from the syringe body 3 (e.g., the linkage member may interfere with the storage container 4 in a radial direction to prevent axial movement of the storage container 4, which will be discussed in detail below), and wherein when the operable component 51 is in the unlocked position, the linkage mechanism 52 is in a second state in which it allows the storage container 4 to be installed into or removed from the syringe body 3. In this embodiment, the linkage mechanism is held by a first internal push rod 33 within the outer housing 32.

[0125] refer to Figures 8 to 10 In this embodiment, the operable component is arranged on the outer housing 32 and is preferably configured as a push-type operable component. The operable component 51 can be mounted on a recess 321 formed on the circumferential sidewall of the outer housing 32 of the syringe body 3, and the operable component 51 can move in the recess 321 relative to the outer housing along the axial direction X between a locked position and an unlocked position.

[0126] In this embodiment, the locked position of the operable component 51 is located distal to the unlocked position. The operable component 51 includes a base 511, an operator engagement portion 512, a sliding portion 513, and a protrusion 514. The base 511 extends in the axial direction X and is generally plate-shaped, providing a base for the other parts and structures of the operable component 51. The operator engagement portion 512 extends radially outward from the radially outer surface of the base 511 and is configured to protrude substantially outward from the outer housing 32, thereby allowing the operator to engage it to move the operable component 51 between the locked and unlocked positions. The operator engagement portion 512 can be various buttons conceivable to those skilled in the art, such as toggle buttons, push buttons, etc. The sliding portion 513 extends radially inward from the radially inner surface of the base 511, and the radially inner surface of the sliding portion can contact and substantially fit against the radially outer surface of the bottom wall 3211 of the recess 321 of the outer housing 32 for movement in the axial direction X on that surface. The protrusion 514 extends radially inward from the radially inner surface of the sliding portion 513 and protrudes radially inward from the opening 32111 at a corresponding position on the bottom wall 3211 of the recess 321 toward the outer housing 32. The opening 32111 extends axially in the X direction and allows the protrusion to move back and forth therein in the axial direction X. The protrusion 514, protruding radially inward from the opening, can engage a linkage mechanism 52 located inside the outer housing 32, such that the linkage mechanism responds to the movement of the protrusion 514 in the opening 32111 of the recess 321 in the axial direction X, switching between the first state (where the protrusion is in the distal position and the linkage mechanism locks the storage container 4) and the second state (where the protrusion is in the proximal position and the linkage mechanism unlocks the storage container 4).

[0127] Furthermore, in order to keep the operable component 51 locked when it is not operated by the operator, a corresponding biasing mechanism is also provided for the operable component 51. Specifically, the sliding part 513 of the operable component includes a columnar component 5131 extending in the axial direction X, and the end wall of the recessed part perpendicular to the axial direction X is provided with a hole 32121 aligned with the columnar component 5131 (that is, the columnar component 5131 and the hole 32121 are aligned in the circumferential direction, and their axes are aligned or approximately aligned with each other). The columnar component 5131 extends from the proximal end surface of the sliding part 513 toward the proximal side, and the hole 32131 is formed in the proximal end wall 3212 of the recessed part 321. A first spring 53 extending in the axial direction X is disposed between the columnar member 5131 and the hole 32121. The first spring includes: a first end portion 531 received and confined within the hole 32121 of the end wall 3212 of the recess; and a second end portion 532 sleeved on the outer periphery of the columnar member 5131. The first spring 53 can bias the operable member 51 toward the locked position via the columnar member 5131. When the operator needs to unlock the retaining device, the operable member 51 can be moved to the unlocked position by pushing or flicking the operator engagement portion 512, at which time the columnar member 5131 compresses the first spring 53 proximally.

[0128] Furthermore, to facilitate the axial movement of the operable component 51 and prevent it from deviating, a guiding device is provided. The guiding device includes a first guide engagement portion extending in the axial direction X, disposed in a recess 321 of the outer housing 32, and a corresponding second guide engagement portion extending in the axial direction X, disposed in a sliding portion 513 of the operable component. The first and second guide engagement portions are configured to cooperate with each other to guide the movement of the sliding portion 513 of the operable component within the recess 321 of the outer housing.

[0129] In this embodiment, the first guide engagement portion is a guide post 322 extending in the axial direction X, fixedly disposed in the recess 321 of the outer housing. The second guide engagement portion is a through hole 5132 extending in the axial direction X, formed in the sliding portion. Each through hole 5132 is shaped and positioned to match the corresponding guide post 322, thereby allowing the sliding portion 513 to move in the axial direction X through the axial movement of each through hole on the corresponding guide post. It is conceivable that the guiding device is not limited to the form of the guide post and through hole provided in this embodiment. Those skilled in the art can adopt other structures according to actual needs, as long as they can guide the axial movement of the operable part 51 relative to the recess 321. Furthermore, Figures 8 to 10In the illustrated embodiment, two through holes 5132 are provided, each located at one end of the sliding portion parallel to the axial direction X, on both sides of the guide post 322. Correspondingly, two guide posts are also provided, located on the recessed portion at positions corresponding to the circumferential positions of the two through holes of the sliding portion. Those skilled in the art can adjust the position and number of the guide posts and through holes according to actual needs.

[0130] In order to fix the guide post 322 to the recess 321, the two ends of each guide post in the axial direction X are respectively received and fixed in two U-shaped fasteners 323 extending outward in the radial direction from the radial outer surface of the bottom wall 3211 of the recess 321. The two U-shaped fasteners are configured to jointly restrict the movement of the guide post, that is, to prevent the guide post from moving in the axial direction and the circumferential direction.

[0131] Further, refer to Figure 5 and Figure 7 The first internal push rod 33 includes a first hollow portion 331 formed on the circumferential sidewall, and the outer housing 32 includes a second hollow portion 322 aligned with the first hollow portion in the circumferential direction of the syringe. The first hollow portion 331 and the second hollow portion 322 together form a viewing window for the operator to observe the storage container 4. Both the first hollow portion 331 and the second hollow portion 322 have an elongated shape extending in the axial direction X, and the second hollow portion is located proximal to the recess 321. The syringe 1 also includes a cap 6 that can engage with the outer housing 32 of the syringe body 3 to cover the recess 321 and the second hollow portion 322. The cap 6 includes a window 61 through which the operator engagement portion 512 of the operable component 51 protrudes from the outer housing 32 when the cap is closed on the outer housing 32, thereby exposing it to the operator for operation.

[0132] Figures 11 to 14 A linkage mechanism 52 according to a preferred embodiment of the present invention is shown. (Reference) Figure 11The linkage mechanism 52 includes a limiting mechanism 521 and a blocking mechanism 522. The limiting mechanism is configured to move in the axial direction X in response to the movement of the protrusion 514 of the operable member 51 in the opening 32111 of the recess 321 of the outer housing, and to move in the axial direction X between a first position and a second position. In this embodiment, the first position is located far from the second position. That is, when the operable part 51 is in the far locked position, the protrusion 514 is in the far position. At this time, the limiting mechanism 521 of the linkage mechanism 52 is in the far first position. The limiting mechanism 521 in the first position keeps the blocking mechanism 522 in a blocking state, so that the blocking mechanism 522 can interfere with the storage container 4 in the radial direction to prevent the storage container from being installed into or removed from the syringe body. When the operable part 51 is operated to the proximal unlock position, the protrusion 514 is in the proximal position. At this time, the limiting mechanism 521 of the linkage mechanism 52 is pushed to the proximal second position by the protrusion 514. The limiting mechanism 521 in the second position switches the blocking mechanism 522 to a non-blocking state, so that the blocking mechanism 522 no longer interferes with the storage container 4, allowing the storage container to be installed into or removed from the syringe body.

[0133] refer to Figures 12 to 13 The blocking mechanism 522 includes a first annular component 5221, which includes a blocking portion 52211. The blocking portion has a through hole 52212 extending radially, and a ball 5222 is accommodated in the through hole. The diameter of the through hole 52212 is not smaller than that of the ball, so as to allow the ball 5222 to move back and forth radially along the inner wall surface of the through hole. Figure 13 As shown (the ball in the through hole is not shown for clarity of the structure of the through hole), the through hole 52212 includes: a first opening end 522121 located radially inward, a second opening end 522122 located radially outward, and an annular first flange 522123 extending from the inner wall surface of the through hole into the through hole at the first opening end. The first flange is sized to allow at least a portion of the ball 5222 to protrude radially inward from the first opening end 522121 of the through hole 52212 to the extent that it interferes with the storage container 4 radially, while preventing the ball from continuing to move radially inward and disengaging from the first opening end 522121 of the through hole.

[0134] Preferably, the first annular component 5221 includes a plurality of circumferentially distributed through holes 52212, each through hole accommodating a ball 5222. More preferably, the plurality of through holes 52212 are arranged at equal intervals.

[0135] Furthermore, the first annular component 5221 also includes an engagement portion 52214 located distal to the blocking portion 52211 of the first annular component. This engagement portion is used to engage the proximal end of the piston rod 22 for mutual fixation with the piston rod. Preferably, the engagement portion 52214 of the first annular component forms a third annular groove 52213 near the distal end of the first annular component, and wherein the proximal end of the piston rod is provided with an elastic latching portion 221 extending proximally in the axial direction X (e.g., ...). Figure 3 As shown), the latching part 221 can be latched onto the distal end face 522131 of the third annular groove (as shown). Figure 13 and Figure 15B As shown), this fixes the piston rod 22 and the first annular component 5221 to each other.

[0136] Furthermore, the proximal end of the first annular member 5221 is configured to be fixed to the distal end of the first internal push rod 33. For example, the proximal end of the first annular member 5221 is formed with an external thread, and the distal end of the first internal push rod 33 is formed with an internal thread that engages with the external thread of the first annular member 5221, thereby enabling the two to be fixed to each other by the threads.

[0137] refer to Figure 14 The limiting mechanism 521 includes a second annular member 5211 sleeved on the outer periphery of the first annular member 5221. This second annular member is configured to move in the axial direction X between a distal first position and a proximal second position in response to movement of the protrusion 514 in the opening 32111 of the recess 321 of the outer housing. The second annular member 5211 includes an annular second flange 52111 extending radially inward from the inner wall surface of the second annular member.

[0138] When the second annular component 5211 is in the first position on the far side (at this time, the operable component 51 is biased by the first spring 53 to the locking position on the far side, and the protrusion 514 is in the far side position), the second flange 52111 is aligned with the through hole 52212 of the blocking mechanism 522 in the axial direction X. At this time, the radially inner surface of the second flange 52111 abuts against the ball 5222 in the through hole 52212 of the blocking mechanism, so as to force at least a portion of the ball to protrude radially inward from the first opening end 522121 of the through hole, thereby interfering with the storage container 4 in the radial direction. When the second annular component 5211 is in the second position (at which point the operator pushes the operator engagement portion 512 proximally, causing the columnar component 5131 of the sliding portion 513 to overcome the biasing force of the first spring and compress the first spring 53 proximally, thereby switching the operable component to the unlocked position, and the protrusion 514 is in the proximity position), the second flange 52111 is offset from the through hole 52212 of the blocking mechanism in the axial direction X, so as to allow the ball 5222 to move freely radially outward to a position where it no longer protrudes radially inward from the first opening end 522121 of the through hole, thereby no longer interfering with or blocking the storage container 4, so that the storage container 4 can be freely installed or removed.

[0139] Furthermore, the limiting mechanism 521 also includes a second spring 5212 (such as...). Figure 12 As shown, a second spring is positioned between the first annular member 5221 and the second annular member 5211, and is sleeved on the outer periphery of the first annular member 5221. The proximal end of the second spring 5212 abuts against the distal end surface of the first inner push rod 33, and the distal end of the second spring abuts against the proximal surface of the second flange 52111 of the second annular member 5211. The second spring 5212 is configured to bias the second annular member distally to the aforementioned first position via the proximal end surface of the second flange 52111.

[0140] The distal side of the second flange 52111 of the second annular component 5211 has a chamfer 52111 (e.g.) Figure 16A As shown), when the operator pushes the operable component 51 to the proximal side, causing the second annular component 5211 of the limiting mechanism 521 of the linkage mechanism 52 to move from the first position to the proximal side along the axial direction X to the second position, the ball 5222 can move along the inclined surface 521111 of the second flange 52111 to a position where it no longer protrudes radially inward from the first opening end of the through hole (no longer blocking the storage container 4).

[0141] The second annular member 5211 also includes a third flange 52112 located on the distal portion of the second annular member 5211, extending radially inward from the inner wall of the second annular member. This third flange is capable of sliding on the outer peripheral surface of the distal portion of the first annular member 5221 during axial movement of the second annular member 5211. The second flange 52111 is located proximal to the third flange 52112, and the second flange forms a first annular groove 52113 between the third flanges. The first annular groove is configured to at least partially accommodate the ball 5222 when the second annular member 5211 is in the aforementioned second position.

[0142] To better illustrate the structure and principle of the retaining device, please refer to the following... Figures 15A-15B as well as Figures 16A-16B ,in, Figures 16A-16B They are Figures 15A-15B A partially enlarged view of the retaining device 5. In these views, the storage container 4 is shown located within the first internal push rod; therefore, the subsequent unlocking process of the retaining device is described using the removal of the storage container 4 from the syringe body 3 as an example. Of course, those skilled in the art will understand that the unlocking process when the storage container 4 is installed into the syringe body 3 is the same or similar, and will not be described further here.

[0143] Figure 15A and Figure 16A The retaining device 5 is shown in the locked state. At this time, the operable part 51 is biased to the remote locked position by the first spring 53, and the linkage mechanism 52 is in a first state that prevents the storage container 4 from being removed. In this first state, the second annular part 5211 in the limiting mechanism 521 of the linkage mechanism is biased to the remote first position by the second spring 5212. At this time, the radially inner surface of the second flange 52111 of the second annular part 5211 abuts against the ball 5222 in the through hole 52212 of the blocking mechanism, forcing at least a portion of the ball to protrude radially inward from the first opening end 522121 of the through hole, thereby interfering with the storage container 4 in the radial direction (in this embodiment, the retaining device is located in the remote part of the syringe body, so the ball 5222 blocks the remote part of the storage container 4), preventing the storage container 4 from being removed from the remote opening of the first internal push rod 3.

[0144] Figure 15B and Figure 16BThe retaining device 5 is shown in the unlocked state. At this time, the operator applies force to the operator engagement 512, causing the operable component to overcome the distal bias of the first spring 53 and move proximally to the unlocked position. Thus, the linkage mechanism 52 is switched to a second state that no longer prevents the storage container 4 from being removed. In this second state, the second annular component 5211 of the limiting mechanism 521 of the linkage mechanism moves proximally to a second position under the push of the protrusion 514 of the operable component, overcoming the distal bias of the second spring 5212. At this point, the second flange 52111 of the second annular component 5211 is misaligned with the through-hole 52212 of the blocking mechanism in the axial direction X, allowing the ball 5222 to move freely radially outward to a position where it no longer protrudes radially inward from the first opening end 522121 of the through-hole, thereby no longer interfering with or obstructing the storage container 4, and thus the storage container 4 can be freely removed.

[0145] In the embodiments described above, the locked position of the operable component 51 and the limiting member 521 is located distal to the unlocked position; however, the present invention is not intended to limit the relative orientation between the unlocked and locked positions. For example, those skilled in the art can adjust the holding device as needed in practical use so that the locked position is proximal to the unlocked position. For example, the first spring 53 described above can be replaced with a spring capable of holding the operable component 51 in the proximal position (biased towards the proximal position) by the columnar member 5131 (e.g., replacing the tension spring with a compression spring); or the first spring 53 and the columnar member 5131 can be arranged on the distal portion of the sliding portion 513 and the hole 32131 can be arranged accordingly in the distal end wall of the recess 321. Similarly, the second spring 5212 can be replaced with a spring capable of holding the second annular member 5211 in a proximal position (biased towards the proximal position) (e.g., replacing a tension spring with a compression spring and fixing it to a corresponding structure at the proximal end of the second annular member 5211); or the second spring 5212 can be arranged on the distal side of the second annular member 5211 such that the proximal end abuts against the distal portion of the second annular member, the distal end being fixed to other components inside the outer housing fixed relative to the first internal push rod, thereby biasing the second annular member to the proximal position.

[0146] Furthermore, to facilitate the operator's removal of the storage container from the syringe body 3, a structure for pushing the storage container out is also provided. (Reference) Figures 15A to 15B as well as Figures 17 to 19Preferably, the holding device further includes a base 36 located at the proximal end of the storage container and configured to conform to the shape of the proximal end of the storage container for receiving and holding the proximal end of the storage container. A third spring 37 is also provided between the base 36 and the aforementioned second internal push rod 34. As described above, the second internal push rod 34 is configured to be located proximal to the first internal push rod 33 and is fixed to the first internal push rod 33 (e.g., fixed to the first internal push rod 33 by the internal thread of the distal end of the second internal push rod and the internal thread of the proximal end of the first internal push rod). The third spring 37 is configured to bias the base 36 distally in the axial direction X.

[0147] Specifically, refer to Figure 17 In a preferred embodiment, the second internal push rod 34 includes: a first axial extension 341, the first axial extension including an elongated first through groove 3411 extending in the axial direction X on a sidewall, the first through groove extending to the distal end of the first axial extension 341; and a second axial extension 342 extending distally from the distal end of the first axial extension 341. An annular fourth flange 3412 extending radially inward from the inner wall surface of the first axial extension is provided approximately at the midpoint of the first axial extension 341 in the axial direction X. The second axial extension 342 engages the proximal end of the first internal push rod 33 (which has the aforementioned internal thread) to secure it to the first internal push rod 33.

[0148] Matching the structure of the second internal push rod 34 described above, refer to Figures 18 to 19 The base 36 includes: a third axial extension 361, the distal portion of which is provided with a protrusion 3611 extending distally, the protrusion corresponding to the first through groove 3411 of the second internal push rod 34, thereby enabling movement in the axial direction X within the first through groove; and a fourth axial extension 362 extending distally from the distal end of the third axial extension 361. Preferably, the first axial extension of the second internal push rod 34 includes a plurality of first through grooves 3411 evenly distributed in the circumferential direction, and correspondingly, the third axial extension of the base includes a plurality of protrusions 3611 corresponding to the first through grooves and in the same number. This embodiment, by removing part of the material from the sidewall of the second internal push rod 34 to create the through groove, can minimize the diameter and axial length of the second internal push rod, thereby reducing the overall size of the syringe body and saving material.

[0149] Besides the aforementioned mating structure of the through groove 3411 and the protrusion 3611, other mating methods can also be used to guide the axial movement of the base 36 in the second internal push rod 34. For example, the multiple protrusions 3611 can be modified into a ring-shaped boss extending continuously in the circumferential direction. Correspondingly, an additional step needs to be provided in the first axial extension 341 of the second internal push rod 34 (this step, for example, in...). Figure 17 (At the axial position near the proximal end of the through groove 3411). In order to set this additional step, the first axial extension 341 of the second internal push rod 34 needs to be thickened or lengthened accordingly to provide space for the step.

[0150] The proximal end of the third spring 37 abuts against the distal surface of the fourth flange 3412 of the second inner push rod 34, and the distal end of the third spring abuts against the inner stepped surface 364 of the connection area between the third axial extension 361 and the fourth axial extension 362 of the base (e.g., Figure 19 (As shown), thereby enabling the base 36 to be biased distally in the axial direction X by the internal stepped surface. The storage container 4 includes a drug storage region 41 located distally and an annular engagement region 42 extending proximally from the proximal end of the drug storage region (see reference). Figure 15A The engagement area 42 is held between the tab of the third axial extension 361 and the fourth axial extension 362 of the base, and the proximal end of the engagement area 42 abuts against the outer stepped surface 363 of the connection area between the third and fourth axial extensions of the base. When the operator operates the operable component 51 to unlock the holding device 5, the storage container 4 is no longer radially restricted by the aforementioned blocking mechanism. At this time, under the distal biasing force of the third spring 37, the base 36, together with the storage container 4, is pushed out of the syringe body 3 through the distal opening of the first internal push rod 33 and the outer housing 32. The arrangement of the base and the third spring allows the storage container to be directly pushed out (ejected) from the syringe body after unlocking the holding device 5 when it is necessary to remove the storage container, without the need for the operator to manually or use an auxiliary tool to pull the storage container out of the syringe body or pour it out.

[0151] More preferably, in order to prevent the storage container 4 from shaking in the first internal push rod 33 during operation (e.g., displacement in the axial, radial or circumferential direction) and to prevent the storage container 4, for example, made of glass, from being broken by the side wall of the first internal push rod 33, a second annular groove 332 is provided on the inner wall surface of the proximal end of the first internal push rod 33. The second annular groove accommodates a rubber ring 38 that contacts the outer peripheral surface of the storage container. The rubber ring is used to prevent the storage container from moving.

[0152] Next, turn Figures 20 to 22This illustrates a retaining device according to another preferred embodiment of the invention. In this embodiment, the overall structure and arrangement of the syringe may be the same as or similar to those described in the foregoing embodiments, and will not be repeated here. Only the differences from the retaining device of the foregoing embodiments will be described.

[0153] In this embodiment, similar to the aforementioned embodiments, the operable component that can be operated by the operator to switch the holding device between a locked state and an unlocked state is arranged on the outer housing 32, the linkage mechanism is held by a tubular first internal push rod 33 within the outer housing of the syringe body, and the storage container 4 can be accommodated within the lumen of the first internal push rod 33.

[0154] refer to Figure 20 The linkage mechanism includes a rocker arm 71 and an elastic element 72 housed and held by a first internal push rod 33. A through slot (in this embodiment, the through slot is a third through slot 334) is provided on the circumferential sidewall of the first internal push rod 33 near its distal end to accommodate and hold the rocker arm and the elastic element. (See reference.) Figure 21 The rocker arm 71 is pivotally mounted to the third through slot 334. Specifically, the rocker arm 71 includes a pin 714 located approximately at the center of the rocker arm, and the rocker arm 71 is mounted to the third through slot 334 via the pin 714. The third through slot 334 includes two opposing sidewalls extending in the axial direction X, each sidewall having a mounting hole 3341 for receiving and securing the end of the pin (see reference). Figure 22 The rocker arm 71 can pivot around the pin 714 in the third through slot 334.

[0155] Continue to refer to Figure 21The lever 71 includes a first leg 711 located proximal to the pin 714 and a second leg 712 located distal to the pin 714. The second leg 712 is capable of switching from a first state that radially interferes with the storage container 4 (e.g., when the storage container is mounted in the first internal push rod and the device is locked, the second leg 712 can interfere with and block the inclined, extending shoulder between the distal portion of the body of the storage container 4 and the head of the storage container 4, thereby preventing the storage container from being removed distally) to a second state that does not interfere with the storage container 4, thereby allowing the storage container 4 to be mounted into or removed from the internal cavity of the first internal push rod. Furthermore, the second leg 712 of the swing arm 71 includes a protrusion 713 extending radially inward from the radially inner surface of the second leg. The protrusion is configured to radially interfere with the storage container 4 when the second leg 712 of the swing arm 71 is in the first state, and to not interfere with the storage container 4 when the second leg 712 is in the second state.

[0156] Furthermore, the elastic element 72 is configured to bias the second leg 712 of the lever 71 toward a first state that radially interferes with the storage container 4. That is, the elastic element can bias the second leg 712 in a radially inward direction, such that the protrusion 713 can radially interfere with the storage container (e.g., when the storage container is properly mounted in the first inner push rod and the second leg 712 is in the first state, the protrusion 713 radially interferes with and blocks the distal portion of the storage container), thereby preventing the storage container from being installed or removed.

[0157] Further, refer to Figure 22 The third through-slot 334 of the first internal push rod 33 includes a first portion 3342 located on the proximal side and a second portion 3343 located on the distal side with a width smaller than the first portion 3342. The width of the first portion 3342 is set smaller than the second portion 3343 so that an elastic element 72 can be arranged radially inward on the circumferential sidewall of the first internal push rod 33 located at the second portion 3343. Specifically, the elastic element 72 is arranged between the radially outer surface of the second leg 712 of the rocker arm 71 and the radially inner surface of the circumferential sidewall of the first internal push rod 33 located at the second portion 3343 of the third through-slot 334, abutting against both surfaces. The elastic element 72 is preferably a tension spring (those skilled in the art can also choose other types of elastic elements 72 according to actual needs, such as a compressible elastic column), capable of biasing the second leg 712 radially inward via the radially outer surface it abuts against, so that the protrusion 713 of the second leg 712 radially interferes with the storage container 4.

[0158] Preferably, in this embodiment, the first leg 711 and the second leg 712 extend substantially parallel to each other.

[0159] Furthermore, the operable component can engage the first leg 711 of the lever 71 to allow the first leg 711 of the lever 71 to move radially inward (as shown in the image) when the operator presses the operable component. Figure 21 (As shown by the near-side arrow direction), causing the rocker arm 71 to pivot about the pin (at this time, the second leg 712 overcomes the biasing force of the elastic element 72 and moves along...) Figure 21 The movement (in the direction of the distal arrow shown) to the protrusion 713 of its second leg 712 does not interfere with the position of the storage container 4.

[0160] Preferably, in order to limit the pivoting range of the rocker arm 71 and prevent the elastic element 72 from excessively biasing the second leg 712, a bottom wall 3344 is formed in the second portion 3343 of the third through groove 334 of the first internal push rod 33. This bottom wall is configured such that when the second leg 712 of the rocker arm 71 is in the first state (the holding device is in the locked state), the distal end of the second leg 712 can overlap the bottom wall 3344, preventing the second leg 712 from moving further radially inward. At the same time, in order to prevent the bottom wall from obstructing the protrusion 713, the distance by which the bottom wall 3344 extends proximally is set such that, within the range of motion of the rocker arm, the bottom wall 3344 never contacts the protrusion 713 of the rocker arm 71.

[0161] This invention is not intended to limit the number of the third through slot, the rocker arm, and the elastic element. Those skilled in the art can provide one third through slot, or multiple third through slots can be provided separately on the circumferential sidewall of the first internal push rod as needed (e.g., two third through slots are arranged symmetrically). Each through slot accommodates and holds the corresponding rocker arm and elastic element.

[0162] Next, turn Figures 23 to 25 This illustrates a holding device according to another preferred embodiment of the invention. This embodiment is referenced. Figures 20 to 22 Variations of the described embodiments. The overall structure and arrangement of the syringe may be the same as or similar to those described in the foregoing embodiments, and will not be repeated here. Only the differences from the holding device in the foregoing embodiments will be described.

[0163] In this embodiment, similar to the reference Figures 20 to 22 In the described embodiment, the operable component capable of being operated by an operator to switch the holding device between a locked and unlocked state is arranged on the outer housing 32, the linkage mechanism is held by a tubular first internal push rod 33 within the outer housing of the syringe body, and the storage container 4 can be accommodated within the lumen of the first internal push rod 33.

[0164] refer to Figure 23 and Figure 24 The linkage mechanism includes a rocker arm 71' and an elastic element 72' housed and held within and by a first internal push rod 33. A through slot (in this embodiment, the through slot is a fourth through slot 335) is provided on the circumferential sidewall of the first internal push rod 33 near its distal end to accommodate and hold the rocker arm 71' and the elastic element 72'. (See reference...) Figure 24 The rocker arm 71' is pivotally mounted to the fourth through slot 335. Specifically, the rocker arm 71' includes a pin 714' located approximately at the center of the rocker arm, and the rocker arm 71' is mounted to the fourth through slot 335 via the pin 714'. The fourth through slot 335 includes two opposing sidewalls extending in the axial direction X, each sidewall having a mounting hole 3351 (see reference) for receiving and securing the end of the pin 714'. Figure 25 The rocker arm 71' can pivot around the pin 714' in the fourth through slot 335.

[0165] In this embodiment, unlike the previous embodiment, the first leg 711' (instead of the distal second leg) of the lever 71' is able to switch from a first state of radially interfering with the storage container 4 (e.g., when the storage container is installed in the first internal push rod and the device is kept in the locked state, the first leg 711' can interfere with and block the inclined extended shoulder between the distal portion of the body of the storage container 4 and the head of the storage container 4, thereby preventing the storage container from being removed in the distal direction) to a second state of not interfering with the storage container 4, thereby allowing the storage container 4 to be installed into or removed from the internal cavity of the first internal push rod. Specifically, the proximal end of the first leg 711' of the lever 71' is configured to radially interfere with the storage container 4 when the first leg 711' of the lever 71' is in the first state, and to not interfere with the distal portion of the storage container 4 when the first leg is in the second state.

[0166] Furthermore, the elastic element 72' is configured to bias the second leg 712' of the lever 71' towards the radially outward direction, thereby causing the lever 71' to pivot about the pin so that the proximal end of the first leg 711' can radially interfere with the position of the storage container 4. That is, the elastic element can bias the second leg 712' towards the radially outward direction, causing the first leg 711' located on the other side of the pin to extend more radially inward relative to the unlocked state, so that the proximal end can contact and interfere with the radially inward storage container 4.

[0167] Preferably, in this embodiment, in order to facilitate the proximal end of the first leg 711' to contact and interfere with the storage container in the locked state of the retaining device, an obtuse angle is formed between the first leg 711' and the second leg 712' in the radially inward direction.

[0168] Further, refer to Figure 25 The fourth through slot 335 of the first internal push rod includes a proximal first portion 3352 and a distal second portion 3353. The first portion 3352 allows the first leg 711' of the rocker arm 71' to pass through and radially interfere with the storage container 4. The second portion 3353 is provided with a bottom wall 3354, and an elastic element 72' is held between the radially outer surface of the bottom wall and the radially inner surface of the second leg 712' of the rocker arm 71', abutting against both surfaces. The elastic element is preferably a tension spring (other types of elastic elements 72' may be selected by those skilled in the art as needed, such as a compressible elastic column, etc.), which can bias the second leg 712' radially outward via the radially inner surface of the second leg 712' it abuts against, so as to hold the first leg 711' in a position where its proximal end radially interferes with the storage container 4.

[0169] Furthermore, the operable component can engage the second leg 712' of the lever 71' to allow the second leg 712' of the lever 71' to overcome the biasing force of the elastic element 72' and move in a radially inward direction (as shown in the image) when the operator presses the operable component. Figure 24 (as shown by the distal arrow), causing the rocker arm 71' to pivot about the pin (at this time, the first leg 711' moves along...) Figure 24 The movement (in the direction of the proximal arrow shown) to the proximal end of the first leg 711' does not interfere with the position of the storage container 4.

[0170] Furthermore, this invention is not intended to limit the number of the third through slot, fourth through slot, rocker arm, and elastic element in the above embodiments. Those skilled in the art can provide one third through slot, or, as needed, provide multiple third through slots separately on the circumferential sidewall of the first internal push rod (e.g., two symmetrically arranged third through slots), each slot accommodating and holding the corresponding rocker arm and elastic element. Similarly, those skilled in the art can provide one fourth through slot, or, as needed, provide multiple fourth through slots separately on the circumferential sidewall of the first internal push rod (e.g., two symmetrically arranged fourth through slots), each slot accommodating and holding the corresponding rocker arm and elastic element.

[0171] Understandable, regarding Figures 23 to 25 as well as Figures 20 to 22 The features in the two described embodiments can be used interchangeably or in combination, and the present invention is not intended to limit them. For example, they can also be used in... Figure 24 The first leg 711' of the swing arm shown is configured similarly to Figure 21 The protrusion 713 of the swing arm shown is such a protrusion that it interferes with the storage container through this protrusion rather than the proximal end of the first leg 711'. Similarly, it is also possible to... Figure 21 The protrusion 713 is omitted from the swing arm 71 shown, and the storage container is interfered with by the distal end of the second leg 712. Furthermore, in both embodiments, the first and second legs can be configured to extend parallel to each other, or to form an obtuse angle between them in the radially inward direction, as those skilled in the art can choose as needed.

[0172] Next, turn Figures 26 to 29 This illustrates a retaining device according to another preferred embodiment of the invention. In this embodiment, the overall structure and arrangement of the syringe may be the same as or similar to those described in the foregoing embodiments, and will not be repeated here. Only the differences from the retaining device of the foregoing embodiments will be described.

[0173] The retaining device according to this embodiment also includes an operable component and a linkage mechanism 82. The linkage mechanism includes: a limiting mechanism configured to move along the axial direction (X) between a first position and a second position in response to movement of the operable component between the locked and unlocked positions; and a blocking mechanism configured to switch between a blocking state and a non-blocking state in response to movement of the limiting mechanism between the first and second positions. When the limiting mechanism is in the first position, the blocking mechanism is in a blocking state, and the blocking mechanism in the blocking state can interfere with the storage container in the radial direction to prevent the storage container from being installed into or removed from the syringe body. When the limiting mechanism is in the second position, the blocking mechanism is in a non-blocking state, and the blocking mechanism in the non-blocking state does not interfere with the storage container to allow the storage container to be installed into or removed from the syringe body.

[0174] In this embodiment, the operable mechanism and the linkage mechanism can be arranged near the proximal portion of the storage container. Of course, those skilled in the art can also adjust the arrangement of the operable mechanism and the linkage mechanism according to actual needs.

[0175] refer to Figure 28The limiting mechanism according to this embodiment includes a slip ring component 821. The slip ring component 821 is disposed within a first internal push rod 33 and sleeved on a storage container. It is responsive to movement of an operable component in the axial direction X between a locked position and an unlocked position, and moves relative to the storage container in the axial direction X between the first and second positions. The slip ring component 821 includes a distal cylindrical portion 8212, the outer peripheral sidewall of which is provided with a protrusion 8213. This protrusion engages with the operable component, allowing it to move axially within a corresponding groove on the inner wall surface of the first internal push rod 33 under the actuation of the operable component, thereby guiding the slip ring component 821 to follow the axial movement of the operable component.

[0176] Preferably, in this embodiment, the operable component is arranged on the outer housing 32 and is configured as a push-type operable component. The operable component in this embodiment can be generally similar to... Figures 7 to 16B The operable mechanism in the described embodiment has only undergone some necessary adjustments. For example, the relevant aspects can be adjusted. Figures 7 to 16B In the embodiment, the protrusion 514 of the operable component 51 is replaced by an operating lever (not shown). The operating lever extends radially inward from the operable component into the hole 82131 of the protrusion 8213 in the cylindrical portion. This hole engages with and is fixed to the operating lever, so that when the operator operates the operable component, the slip ring component 821 can be moved axially through the engagement between the operating lever and the hole 82131. Correspondingly, a second through groove 333 is provided on the first internal push rod 33 at the position corresponding to the protrusion. When the slip ring component 821 moves between the first position and the second position, the second through groove 333 allows the hole 82131 of the protrusion 8213 to be exposed to the operating lever (i.e., the hole 82131 is not covered by the circumferential sidewall of the first internal push rod at all positions within the axial movement range of the protrusion).

[0177] Preferably, the cylindrical portion 8212 of the slip ring component includes two protrusions 8213 symmetrically arranged about a central axis, each protrusion including the aforementioned hole 82131. Correspondingly, two operable components are symmetrically arranged about the central axis on the outer peripheral sidewall of the outer housing, each operable component engaging with the hole 82131 of each protrusion via an operating rod. Correspondingly, the first internal push rod 33 also includes two symmetrically arranged second through slots 333.

[0178] The slip ring component 821 also includes a proximal truncated conical portion 8211 extending proximally from the cylindrical portion 8212, the truncated conical portion 8211 being used to engage the blocking mechanism 822 to switch the blocking mechanism between a blocking state and a non-blocking state.

[0179] The blocking mechanism 822 is positioned proximal to the limiting mechanism and includes: an elastic ring member 8221, which is disposed within the first internal push rod 33 and sleeved on the storage container 4, and is capable of engaging with the truncated conical portion 8211 of the distal slip ring member 821 to switch between a blocking state and a non-blocking state; and

[0180] A mounting component 8222 is used to securely mount the elastic ring component 8221 to the first internal push rod 33. The mounting component includes a distal tubular element 82221 and a proximal annular limiting element 82821. The tubular element 82221 is engaged in a corresponding fixing groove within the first internal push rod 33 and can be fixedly connected to the elastic ring component 8221. The annular limiting element 82821 is disposed adjacent to the proximal side of the tubular element 82221 to restrict the axial movement of the tubular element (i.e., to restrict the tubular element proximal to prevent the operator's unlocking force from causing the tubular element to disengage from the fixing groove of the first internal push rod and slide proximal).

[0181] The elastic annular component 8221 includes a plurality of elastic elements 82211 continuously arranged in the circumferential direction. Each elastic element 82211 includes: a fixing portion 822111 located radially outward for fixing the elastic element to the distal edge of the tubular component 82221; and a deformable portion 822112 capable of elastically deforming to reduce the included angle R between the deformable portion and the fixing portion (e.g., ...). Figure 29 (As shown) Switching between the first angle and the second angle.

[0182] When the slip ring component 821 of the limiting mechanism is in the first position at the far side, the truncated conical portion 8211 does not engage with the annular component 8221, and the deformable portion 822112 of each of the plurality of elastic elements 82211 is in a stress-free state. At this time, the angle between the deformable portion 822112 and the fixed portion 822111 is the first angle, and the radially inner end of the deformable portion 822112 can contact and interfere with the storage container 4. When the slip ring component 821 of the limiting mechanism moves to the second position at the near side, the truncated conical portion 8211 biases the deformable portion of each of the plurality of elastic elements 82211 radially outward, so that the angle between the deformable portion 822112 of each of the plurality of elastic elements 82211 and the fixed portion 822111 changes from the first angle to the second angle due to pressure. At this time, the radially inner end of the deformable portion 822112 no longer contacts the storage container. The first angle is greater than the second angle. In other words, when the deformable part 822112 is engaged and force is applied by the truncated conical part 8211 of the slip ring component 821, it can deform in a direction closer to the fixed part 822111 (e.g. Figure 29 (As shown).

[0183] like Figure 28 As shown, the radially inner ends of the deformable portions 822112 of a plurality of elastic elements 82211 collectively form the opening 82212 of the elastic annular member 8221. When the angle between the deformable portion 822112 of each of the plurality of elastic elements 82211 and the fixed portion 822111 is a first angle (i.e., the slip ring member 821 of the limiting mechanism is located in the distal first position, and the truncated conical portion 8211 does not engage the annular member 8221), the opening 82212 has a first diameter. When the angle between the deformable portion 822112 of each of the plurality of elastic elements 82211 and the fixed portion 822111 is a second angle (when the slip ring member 821 of the limiting mechanism moves proximally to the second position, the truncated conical portion 8211 biases the deformable portion of each of the plurality of elastic elements 82211 radially outward), the opening 82212 has a second diameter. The second diameter is larger than the first diameter. In other words, when the operator operates the operable component (from the locked position to the unlocked position) so that the aforementioned operating lever moves the slip ring component 821 of the limiting mechanism from the first position to the second position through the hole 82131, the truncated conical portion 8211 of the slip ring component 821 radially outwards presses the deformable portion 822112 of each of the multiple elastic elements 82211 of the elastic ring component 8221, so that the opening 82212 defined by the elastic ring component 8221 becomes larger, thereby no longer contacting or interfering with the storage container 4, so that the storage container 4 can be freely installed or removed.

[0184] Furthermore, in this embodiment, the storage container 4 can also be installed in the first internal push rod. (See reference...) Figure 27 The first internal push rod 33 includes a second through groove 333 corresponding to the hole 82131 on the protrusion 8213 of the slip ring component 821. The groove allows the hole 82131 to be exposed in the second through groove 333 when the slip ring component 821 is in the first position and the second position, so that the hole 82131 can engage with the operating lever of the operable component throughout the axial movement of the slip ring, so that it can be driven by the operable component to perform axial movement.

[0185] Next, turn Figures 30 to 36 This illustrates a retaining device according to another preferred embodiment of the invention. In this embodiment, the overall structure and arrangement of the syringe may be the same as or similar to those described in the foregoing embodiments, and will not be repeated here. Only the differences from the retaining device of the foregoing embodiments will be described.

[0186] Next, turn Figures 30 to 36This illustrates a retaining device according to another preferred embodiment of the invention. In this embodiment, the overall structure and arrangement of the syringe may be the same as or similar to those described in the foregoing embodiments, and will not be repeated here. Only the differences from the retaining device of the foregoing embodiments will be described.

[0187] In this embodiment, the operable component is arranged on the outer housing 32 and is configured as a press-operated component. (See reference) Figure 30 The linkage mechanism is held in place by a first internal push rod 33 within the outer housing. The storage container can be housed inside the first internal push rod 33.

[0188] In this embodiment, the linkage mechanism includes: a limiting mechanism configured to move in a vertical radial direction between an upper first position and a lower second position in response to movement of the operable component in a locked position and an unlocked position; and a blocking mechanism configured to switch between a closed blocking state and an open non-blocking state in response to movement of the limiting mechanism in a vertical radial direction between the upper first position and the lower second position.

[0189] It should be noted that the directional descriptions such as "vertical," "horizontal," "up," "down," "top," "bottom," "left," and "right" mentioned in this embodiment are all relative to the axial direction X of the syringe's longitudinal extension, and are not absolute descriptions. For example, the vertical direction in this embodiment refers to a specific radial direction extending perpendicular to the axial direction X (see reference). Figure 31 The vertical direction refers to the direction between the axial direction X and the horizontal direction, while the horizontal direction refers to another specific radial direction that is perpendicular to the axial direction X and extends perpendicularly to the aforementioned horizontal direction (see reference). Figure 31 (The left and right directions in the middle).

[0190] refer to Figure 31 and Figure 32 The limiting mechanism of this embodiment includes a retaining ring 921, which can be engaged by the operable component such that when the operator presses down on the operable component, the retaining ring moves downward in a vertical radial direction. The retaining ring 921 can be fitted over the storage container 4 radially outward. The retaining ring 921 includes a top 9211 that can be engaged by the operable component and two integrally arc-shaped arms extending from the top to both sides. The end 9213 of each of the two arms away from the top includes a guide groove 9214 for engaging a blocking mechanism and guiding the movement of the blocking mechanism. The guide groove 9213 extends in a horizontal radial direction.

[0191] refer to Figure 35 and Figure 35To accommodate the retaining ring 921, the first internal push rod 33 is formed with a groove 339 for receiving the retaining ring 921. The groove matches the shape of the retaining ring 921, allowing the retaining ring to move in a vertical radial direction between an upper first position (corresponding to the locked state of the retaining device and the locked position of the operable component) and a lower second position (corresponding to the unlocked state of the retaining device and the unlocked position of the operable component). The groove 921 includes two guide portions 337 extending in a vertical radial direction, each guide portion receiving one of the two ends 9213 of the two arms of the retaining ring 921 away from the top, and allowing that end portion to move up and down in a vertical radial direction therein.

[0192] Furthermore, the slot 339 of the first internal push rod 33 includes a first tongue 336 extending distally from a proximal surface of the slot in a direction perpendicular to the axial direction. The first tongue is located directly below the top of the retaining ring 9211 and is used to retain the elastic element (which will be described in detail below and is not shown in the figures) together with the top of the retaining ring 921.

[0193] Specifically, the limiting mechanism also includes an elastic element that abuts against the hole 9212 on the bottom surface of the top of the retaining ring 921 and the top surface of the first tongue 336, and is configured to bias the retaining ring 921 upwards to a first position (corresponding to the locked state of the retaining device and the locked position of the operable component). The elastic element can be, for example, a tension spring that can bias the retaining ring upwards when the operator does not press the operable component, or other elastic components that can achieve the same function.

[0194] Further, refer to Figure 31 and Figure 33 The blocking mechanism includes two generally arc-shaped swing arms 9221 (each swing arm is approximately crescent-shaped), each swing arm being pivotally connected to a first internal push rod 33 via its bottom end. For example, each swing arm has a hole 9222 extending through it in the axial direction X at its bottom end. Corresponding to the hole 9222 of each swing arm, the stepped surface of the first internal push rod extending perpendicular to the axial direction X is provided with a hole 338. The hole 338 and the hole 9222 can be connected by a component such as a pin, so that each swing arm can be pivotally connected to the first internal push rod.

[0195] Furthermore, a guide pin 9223 is provided at approximately the middle position of each swing arm, which is movable along the guide groove 9213 of the arm portion of the retaining ring 921 located on the same side. When the retaining ring 921 is in the upper first position (corresponding to the locked position of the retaining device), each guide pin 9223 is located at the radially inner end of the corresponding guide groove 9213, such that the two swing arms 9221 together form a closed blocking state. In this blocking state, the two swing arms radially interfere with the storage container, thereby preventing the storage container from being installed into or removed from the first internal push rod. When the operator presses the operable component, causing the retaining ring 921 to move downward (e.g., ...), the storage container is closed. Figure 31 When the retaining ring 921 moves to the second position (corresponding to the unlocked position of the retaining device) via the arrow at the top of the retaining ring 9213, the retaining ring 921 drives the corresponding guide pin 9223 to move to the radially outer end of the guide groove 9213 (that is, when the retaining ring moves downward, the guide groove 9213 forces the guide pin 9223 therein to move to the radially outer end of the guide groove 9213, thereby changing the corresponding swing arm from closed to open), causing the two swing arms 9221 to move radially outward (as shown by the arrow at the top of the retaining ring 9213). Figure 31 As indicated by the arrow at the swing arm, the two swing arms 9221 shown in the figure are in an open, unobstructed state (with the guide pin located at the outer end of the guide groove) to together form the open, unobstructed state. In this unobstructed state, the two swing arms do not interfere with the storage container, thereby allowing the storage container to be installed into or removed from the first internal push rod.

[0196] Preferably, the retaining device according to this embodiment further includes an annular limiting element 923 for limiting the axial position of the blocking mechanism and the limiting mechanism. The limiting element 923 is located distal to the blocking mechanism and the limiting mechanism to prevent the blocking mechanism and the limiting mechanism from moving distally away from the first internal push rod 33. Preferably, in this embodiment, the blocking mechanism is located distal to the limiting mechanism, and the limiting element 923 includes: an annular flange 9231 extending proximally, which is capable of abutting the two swing arms 9221 distally; and a second tongue 9232 extending proximally beyond the annular flange 9231, which is capable of abutting the top 9211 of the retaining ring 921 distally when the retaining ring 921 is in the first position above. Preferably, the second tongue 9232 can cooperate with the corresponding fifth through groove 3310 on the first internal push rod 33, so that when the limiting element 923 is installed on the first internal push rod 33, the second tongue 9232 is accommodated and held in the fifth through groove 3310. Figure 30 The diagram schematically shows the state in which the limiting element 923 is installed at the distal end of the first internal push rod 33.

[0197] Furthermore, it should be understood that, regarding Figures 1 to 19The overall structure and other suitable features of the described syringe can be applied, individually or in combination, to the embodiments described with reference to the other figures. For example, the principle, basic construction, drug aspiration and injection process of the needle-free syringe, etc. For example, see reference... Figures 15A to 15B as well as Figures 17 to 19 The structures provided for pushing the storage container out of the syringe body 3 to facilitate removal of the storage container by the operator (e.g., the base 36 between the second internal push rod 34 and the proximal portion of the storage container, and the third spring 37 between the base and the second internal push rod); as well as the second annular groove 332 of the first internal push rod 33 and the cooperating rubber ring 38 (to prevent the storage container 4 from shaking in the first internal push rod 33 during operation), and the combinations of features and the mode of action of the features, are also applicable to other embodiments.

[0198] The present invention also provides a needle-free syringe comprising the syringe body described above and a storage container located within an outer shell of the syringe body. The storage container is removably mounted in the syringe for use with the syringe. The syringe also includes a retaining device as described in the various embodiments above, configured to either prevent the storage container from being mounted in or removed from the syringe in a locked state, or to allow the storage container to be mounted in or removed from the syringe.

[0199] It should be noted that the above embodiments of the present invention can be combined and / or modified in various ways, and the results of such combinations and / or modifications should also be considered as embodiments of the present invention. The above description of various embodiments of the present invention is provided for illustrative purposes to a person skilled in the art. It is not intended to exclude or limit the present invention to a single disclosed embodiment. As taught above, those skilled in the art will understand various alternatives and variations of the present invention. Therefore, although some alternative embodiments have been specifically described, those skilled in the art will understand or relatively easily develop other embodiments. The present invention is intended to include all alternatives, modifications, and variations of the present invention described herein, as well as other embodiments falling within the spirit and scope of the present invention described above.

Claims

1. A retaining device for a storage container (4) of a needleless injector, the storage container being removably mounted in the needleless injector (1), characterized in that, The retaining device is configured to switch between a locked state and an unlocked state, wherein in the locked state, the retaining device prevents the storage container from being installed into the syringe body (3) of the needleless injector and prevents the storage container from being removed from the syringe body, and in the unlocked state, the retaining device allows the storage container to be installed into or removed from the syringe body, wherein the retaining device includes: An operable component, which can be operated by an operator to move between a locked position and an unlocked position, so as to switch the holding device between the locked state and the unlocked state; A linkage mechanism is configured to switch between a first state and a second state in response to movement of the operable component between a locked position and an unlocked position. When the operable component is in the locked position, the linkage mechanism is in the first state to prevent the storage container (4) from being installed into the syringe body (3) and to prevent the storage container (4) from being removed from the syringe body. When the operable component is in the unlocked position, the linkage mechanism is in the second state, allowing the storage container (4) to be installed into or removed from the syringe body (3), and The retaining device is configured such that the operator must switch the retaining device to the unlocked state before installing the storage container in the assembly step and before removing the storage container in the disassembly step.

2. The holding device according to claim 1, characterized in that The linkage mechanism is held by a tubular first internal push rod (33) within the outer housing of the syringe body, wherein the storage container can be accommodated inside the first internal push rod (33).

3. The holding device according to claim 2, characterized in that, The linkage mechanism includes: A limiting mechanism, configured to move between a first position and a second position in response to movement of the operable member between the locked position and the unlocked position; and A blocking mechanism is configured to switch between a blocking state and a non-blocking state in response to movement of the limiting mechanism between a first position and a second position. When the limiting mechanism is in the first position, the blocking mechanism is in a blocking state. In this blocking state, the blocking mechanism can interfere with the storage container in the radial direction, thereby preventing the storage container from being installed into the syringe body and preventing the storage container from being removed from the syringe body. When the limiting mechanism is in the second position, the blocking mechanism is in a non-blocking state. In the non-blocking state, the blocking mechanism does not interfere with the storage container, so that the storage container can be installed into the syringe body or removed from the syringe body.

4. The holding device according to claim 3, characterized in that, The operable component is arranged on the outer housing (32) and is configured as a press-operable component.

5. The holding device according to claim 3, characterized in that, The operable component is arranged on the outer housing (32) and is configured as a push-type operable component.

6. The holding device according to claim 5, characterized in that, The limiting mechanism is configured to respond to the movement of the operable component in the axial direction (X) between the locked position and the unlocked position, and to move in the axial direction (X) between the first position and the second position.

7. The holding device (5) according to claim 6, characterized in that, The operable component (51) can be mounted in a recess (321) on the circumferential sidewall of the outer casing (32) of the syringe body (3), and The operable component (51) is capable of moving in the recess (321) relative to the outer housing along the axial direction (X) between the locked position and the unlocked position.

8. The holding device (5) according to claim 7, characterized in that, The operable component (51) includes: A base (511) extending in the axial direction (X); An operator engagement (512) is configured to extend radially outward from the radially outer surface of the base (511) and to be engaged by an operator to operate the operable component to move between the locked position and the unlocked position. A sliding portion (513) is configured to extend inwardly from the radially inner surface of the base (511) along the radial direction, and the radially inner surface of the sliding portion is capable of contacting the radially outer surface of the bottom wall (3211) of the recess (321) of the outer housing (32) to move along the axial direction (X) on that surface; and A protrusion (514) is configured to extend radially inward from the radially inner surface of the sliding portion (513) and protrude radially inward from an opening (32111) at a corresponding position on the bottom wall (3211) of the recess (321) toward the outer housing (32), the opening (32111) extending along the axial direction (X) and allowing the protrusion to move therein along the axial direction (X), and The protrusion (514) is capable of engaging the linkage mechanism (52) so that the linkage mechanism switches between a first state and a second state in response to the movement of the protrusion (514) in the opening (32111) of the recess (321) along the axial direction (X).

9. The holding device (5) according to claim 8, characterized in that, The sliding portion (513) of the operable component includes a columnar member (5131) extending along the axial direction (X), and the end wall of the recess perpendicular to the axial direction (X) is provided with a hole (32121) aligned with the columnar member (5131). The retaining device (5) further includes a first spring (53) extending along the axial direction (X), the first spring comprising: The first end portion (531) is received and confined within the hole (32121) of the end wall (3212) of the recess; and The second end (532) is fitted onto the outer periphery of the columnar member (5131). The first spring (53) is configured to bias the operable component (51) toward the locking position via the columnar component (5131).

10. The holding device (5) according to claim 9, characterized in that, The locked position of the operable component (51) is located at the far side relative to the unlocked position. The columnar member (5131) extends proximally from the surface of the sliding portion (513), and the hole (32131) is formed within the proximal end wall (3212) of the recess (321). The first spring (53) is configured to bias the operable member (51) toward the locking position at a distance via the columnar member (5131).

11. The holding device (5) according to claim 10, characterized in that, The retaining device further includes a first guide engagement portion extending in the axial direction (X) in a recess (321) of the outer housing (32). The sliding portion of the operable component includes a second guide engagement portion extending along the axial direction (X), and The first guide engagement and the second guide engagement are configured to cooperate with each other to guide the movement of the sliding part (513) of the operable component in the recess (321) of the outer housing.

12. The holding device (5) according to claim 11, characterized in that, The first guide engagement is configured to include at least one guide post (322) fixedly disposed in the recess of the outer housing, and the second guide engagement is configured to include at least one through hole (5132) extending through the sliding portion in the axial direction (X), each through hole being shaped to fit the corresponding guide post (322), thereby allowing the sliding portion (513) to move in the axial direction (X) by means of axial movement of each through hole on the corresponding guide post.

13. The holding device (5) according to claim 12, characterized in that, The two ends of each guide post in the axial direction (X) are respectively received and fixed in two U-shaped fasteners (323) extending outward in the radial direction from the radial outer surface of the bottom wall (3211) of the recess (321), the two U-shaped fasteners being configured to jointly restrict the movement of the guide post.

14. The holding device (5) according to claim 13, characterized in that, The sliding part has two through holes (5132), which are respectively opened at two ends of the sliding part parallel to the axial direction (X), and correspondingly, The number of guide posts (522) is two, and the two guide posts are respectively located on the recessed part at positions corresponding to the circumferential positions of the two through holes of the sliding part.

15. The holding device (5) according to any one of claims 8 to 14, characterized in that, The blocking mechanism (522) includes a first annular component (5221), which includes a blocking portion (52211) having a through hole (52212) extending in the radial direction, and a ball (5222) is accommodated in the through hole. The diameter of the through hole (52212) is not smaller than that of the sphere, so as to allow the sphere (5222) to move back and forth along the inner wall surface of the through hole in the radial direction, and The through hole (52212) includes: a first opening end (522121) located radially inward, a second opening end (522122) located radially outward, and an annular first flange (522123) extending from the inner wall surface of the through hole into the through hole at the first opening end. The first flange is sized to allow at least a portion of the ball (5222) to protrude radially inward from the first opening end (522121) of the through hole (52212), while preventing the ball from continuing to move radially inward and dislodging from the through hole.

16. The holding device (5) according to claim 15, characterized in that, The limiting mechanism (521) includes a second annular member (5211) sleeved on the outer periphery of the first annular member (5221), the second annular member being configured to move in the axial direction (X) in response to movement of the protrusion (514) in the opening (32111) of the recess (321) of the outer housing, and between the first position and the second position. The second annular component (5211) includes an annular second flange (52111) extending radially inward from the inner wall surface of the second annular component. When the second annular component (5211) is in the first position, the second flange (52111) is aligned with the through hole (52212) of the blocking mechanism (522) in the axial direction (X), and the radially inner surface of the second flange (52111) abuts against the ball (5222) in the through hole (52212) of the blocking mechanism, forcing at least a portion of the ball to protrude radially inward from the first opening end (522121) of the through hole, thereby interfering with the storage container (4) in the radial direction. When the second annular component (5211) is in the second position, the second flange (52111) is offset from the through hole (52212) of the blocking mechanism in the axial direction (X) so as to allow the ball (5222) to move freely radially outward to a position where it no longer protrudes radially inward from the first opening end (522121) of the through hole, thereby no longer interfering with the storage container (4).

17. The holding device (5) according to claim 16, characterized in that, The proximal end of the first annular component (5221) is configured to be fixed to the distal end of the first internal push rod (33).

18. The holding device (5) according to claim 17, characterized in that, The first position is located distally relative to the second position. The limiting mechanism (521) further includes a second spring (5212), which is positioned between the first annular component and the second annular component, and is sleeved on the outer periphery of the first annular component. The proximal end of the second spring (5212) abuts against the distal end surface of the first inner push rod (33), and the distal end of the second spring abuts against the proximal surface of the second flange (52111) of the second annular member (5211). The second spring (5212) is configured to bias the second annular member toward the first position distally via the proximal end surface of the second flange (52111).

19. The holding device (5) according to claim 18, characterized in that, The proximal end of the first annular component (5221) is formed with an external thread, and the distal end of the first internal push rod (33) is formed with an internal thread that engages with the external thread of the first annular component (5221).

20. The holding device (5) according to claim 19, characterized in that, The second annular component (5211) has a chamfer (521111) formed on the distal side of the second flange (521111), wherein, as the second annular component (5211) moves from the first position toward the proximal side to the second position along the axial direction (X), the ball can move along the chamfer (521111) of the second flange to a position where it no longer protrudes radially inward from the first opening end of the through hole.

21. The holding device (5) according to claim 20, characterized in that, The second annular component (5211) further includes a third flange (52112) located on the distal portion of the second annular component (5211), extending radially inward from the inner wall of the second annular component. The second flange (52111) is located near the third flange (52112), and the second flange forms a first annular groove (52113) between the third flanges. The first annular groove is configured to at least partially accommodate the ball (5222) when the second annular member is in the second position.

22. The holding device (5) according to claim 21, characterized in that, The first annular component (5221) includes a plurality of circumferentially distributed through holes (52212), each through hole accommodating the ball (5222).

23. The holding device (5) according to claim 22, characterized in that, The multiple through holes (52212) are arranged at equal intervals.

24. The holding device (5) according to claim 2, characterized in that, The holding device further includes a base (36) for holding the storage container (4), the base being located near the storage container and configured to fit the shape of the near end of the storage container for receiving and holding the near end of the storage container.

25. The holding device (5) according to claim 24, characterized in that, The retaining device further includes a third spring (37) configured to be positioned between the base (36) and a tubular second internal push rod (34) within the outer housing (32) of the syringe body. The second internal push rod (34) is configured to be located proximal to the first internal push rod (33) and fixed to it. The third spring (37) is configured to bias the base (36) distally along the axial direction (X).

26. The holding device (5) according to claim 25, characterized in that, The second internal push rod (34) includes: A first axial extension (341) includes an elongated first through-slot (3411) extending in the axial direction (X) on a sidewall, the first through-slot extending to a distal end of the first axial extension; and A second axial extension (342) extends distally from the distal end of the first axial extension. Wherein, an annular fourth flange (3412) extending radially inward from the inner wall surface of the first axial extension (341) is provided at approximately the midpoint of the axial direction (X) of the first axial extension (341), and, The second axial extension (342) is used to engage the proximal end of the first internal push rod (33) to fix it to the first internal push rod (33).

27. The holding device (5) according to claim 26, characterized in that, The base (36) includes: A third axial extension (361) is provided, the distal portion of which is provided with a protrusion (3611) extending distally, the protrusion corresponding to the first through groove (3411) of the second internal push rod (34), thereby enabling it to move within the first through groove in the axial direction (X); and A fourth axial extension (362) extends distally from the distal end of the third axial extension (361).

28. The holding device (5) according to claim 27, characterized in that, The proximal end of the third spring (37) abuts against the distal surface of the fourth flange (3412) of the second internal push rod (34), and the distal end of the third spring abuts against the internal step surface (364) of the connection area between the third axial extension (361) and the fourth axial extension (362) of the base, which extends perpendicular to the axial direction, thereby enabling the base (36) to be biased distally in the axial direction (X) by the internal step surface.

29. The holding device (5) according to claim 28, characterized in that, The storage container (4) includes a distal drug storage area (41) and an annular engagement area (42) extending proximally from the proximal end of the drug storage area. The engagement area is held between a tab of a third axial extension (361) of the base and a fourth axial extension (362). The proximal end of the engagement area (42) abuts against the outer step surface (363) of the connection area between the third axial extension and the fourth axial extension of the base, which extends perpendicularly to the axial direction, such that when the operator operates to unlock the retaining device (5), the storage container can be pushed out of the syringe body by the third spring (37) along with the base.

30. The holding device (5) according to claim 26, characterized in that, The second axial extension (342) of the second internal push rod (34) is provided with an internal thread, and the proximal end of the first internal push rod (33) is provided with an external thread that engages with the internal thread of the second axial extension.

31. The holding device (5) according to claim 26, characterized in that, The first axial extension of the second internal push rod (34) includes a plurality of first through slots (3411), and the third axial extension of the base includes a plurality of tabs (3611) corresponding to the positions of the first through slots and in the same number.

32. The holding device (5) according to claim 2, characterized in that, The inner wall surface of the proximal end of the first internal push rod (33) is provided with a second annular groove (332), in which a rubber ring (38) is accommodated to contact the outer peripheral surface of the storage container, the rubber ring being used to prevent the storage container from moving.

33. The holding device (5) according to claim 15, characterized in that, The first annular component (5221) also includes a connecting portion (52214) located on the distal side of the blocking portion (52211), which is used to engage the piston rod (22) of the injection head (2) to fix it to the piston rod.

34. The holding device (5) according to claim 33, characterized in that, The engaging portion (52214) of the first annular component has a third annular groove (52213) near the distal end of the first annular component, and The piston rod has a resilient snap-fit ​​portion (221) extending proximally along the axial direction (X) at its proximal end. The snap-fit ​​portion can be snapped onto the distal end face (522131) of the third annular groove, thereby fixing the piston rod (22) and the first annular component (5221) to each other.

35. The holding device according to claim 6, characterized in that, The limiting mechanism includes a slip ring component (821), which is arranged in the first internal push rod (33) and sleeved on the storage container (4). The slip ring component is responsive to movement of the operable component in the axial direction (X) between the locked and unlocked positions, and moves relative to the storage container in the axial direction (X) between the first and second positions, wherein the slip ring component includes: The distal cylindrical portion (8212) has a protrusion (8213) arranged on its outer peripheral sidewall. This protrusion engages with the operable component, allowing it to move axially within a corresponding groove on the inner wall surface of the first internal push rod (33) under the actuation of the operable component, thereby guiding the axial movement of the slip ring component (821). A truncated conical portion (8211) on the proximal side, the truncated conical portion being used to engage the blocking mechanism (822) to switch the blocking mechanism between the blocking state and the non-blocking state.

36. The holding device according to claim 35, characterized in that, The blocking mechanism is positioned near the limiting mechanism and includes: A resilient ring component (8221), which is arranged in the first internal push rod (33) and sleeved on the storage container (4), is capable of engaging with the truncated conical portion (8211) of the distal slip ring component (821); and A mounting component (8222) for securing the elastic ring component (8221) to the first internal push rod (33), the mounting component comprising a distal tubular element (82221) and a proximal annular limiting element (82821). The tubular element (82221) is fitted into a corresponding fixing groove within the first internal push rod (33) and is fixedly connected to the elastic ring component (8221). The annular limiting element (82821) is disposed adjacent to the tubular element on the near side, and is used to limit the axial movement of the tubular element.

37. The holding device according to claim 36, characterized in that, The elastic annular component (8221) includes a plurality of elastic elements (82211) continuously arranged in the circumferential direction, each elastic element (82211) including: A fixing portion (822111), located radially outward, for securing the elastic element to the distal edge of the tubular element (82221); and The deformable portion (822112) is capable of elastically deforming such that the included angle (R) between the deformable portion and the fixed portion switches between a first angle and a second angle.

38. The holding device according to claim 37, characterized in that, When the slip ring component (821) of the limiting mechanism is in the first position on the far side, the truncated conical portion (8211) does not engage the annular component (8221), and the included angle between the deformable portion (822112) and the fixed portion (822111) of each of the plurality of elastic elements (82211) is the first included angle, at which time the radially inner end of the deformable portion (822112) contacts and interferes with the storage container; When the slip ring component (821) of the limiting mechanism moves proximally to the second position, the truncated conical portion (8211) biases the deformable portion of each of the plurality of elastic elements (82211) radially outward, causing the angle between the deformable portion (822112) of each of the plurality of elastic elements (822111) and the fixed portion (822111) to change from the first angle to the second angle. At this time, the radially inner end of the deformable portion (822112) does not contact the storage container, and Wherein, the first included angle is greater than the second included angle.

39. The holding device according to claim 38, characterized in that, The radially inner ends of the deformable portions (822112) of the plurality of elastic elements (82211) together form the opening (82212) of the elastic annular component (8221). Wherein, when the angle between the deformable portion (822112) and the fixed portion (822111) of each of the plurality of elastic elements (82211) is a first angle, the opening (82212) has a first diameter; Wherein, when the angle between the deformable portion (822112) and the fixed portion (822111) of each of the plurality of elastic elements (82211) is a second angle, the opening (82212) has a second diameter, and The second diameter is larger than the first diameter.

40. The holding device according to claim 35, characterized in that, The bump (8213) includes a hole (82131) configured to engage with the operating lever of the operable component.

41. The holding device according to claim 40, characterized in that, A second through groove (333) is provided on the first internal push rod (33) at the position corresponding to the protrusion. When the slip ring component (821) moves between the first position and the second position, the second through groove (333) allows the hole (82131) of the protrusion to be exposed to the operating rod.

42. The holding device according to claim 41, characterized in that, The cylindrical portion (8212) of the slip ring component includes two symmetrically arranged protrusions (8213), and Accordingly, the first internal push rod (33) includes two second through slots (333) arranged symmetrically.

43. The holding device according to claim 2, characterized in that, The operable component is arranged on the outer housing (32) and is configured as a press-operated component. The linkage mechanism includes a swing arm and an elastic element that are housed inside and held by the first internal push rod (33).

44. The holding device according to claim 43, characterized in that, The first internal push rod (33) has a through slot on the circumferential sidewall near the distal end for receiving and holding the rocker arm and the elastic element, wherein the rocker arm is pivotally mounted to the through slot.

45. The holding device according to claim 44, characterized in that, The rocker arm includes a pin located approximately at the center of the rocker arm, and the rocker arm is mounted to the through slot via the pin. The through groove includes two opposing sidewalls extending in the axial direction (X), each sidewall having a mounting hole for receiving and fixing the end of the pin. The rocker arm is capable of pivoting around the pin in the through slot.

46. ​​The holding device according to claim 45, characterized in that, The rocker arm includes a first leg located near the pin and a second leg located far from the pin. One of the first leg and the second leg is capable of switching from a first state of radially interfering with the storage container (4) to a second state of not interfering with the storage container (4) in response to the operation of the operable component being pressed by the operator to move from the locked position to the unlocked position.

47. The holding device according to claim 46, characterized in that, The second leg (712) of the lever (71) is capable of switching from a first state of radially interfering with the storage container (4) to a second state of not interfering with the storage container (4) in response to the operation of the operable component being pressed by the operator to move from the locked position to the unlocked position, and The second leg (712) of the swing arm (71) includes a protrusion (713) extending radially inward from the radially inner surface of the second leg. The protrusion is configured to radially interfere with the storage container (4) when the second leg (712) of the swing arm (71) is in the first state, and to not interfere with the storage container (4) when the second leg is in the second state.

48. The holding device according to claim 47, characterized in that, The elastic element (72) is configured to bias the second leg (712) of the lever (71) toward a first state that radially interferes with the storage container (4).

49. The holding device according to claim 48, characterized in that, The through slot of the first internal push rod for receiving and holding the rocker arm is a third through slot (334), which includes a first portion (3342) on the proximal side and a second portion (3343) on the distal side with a width smaller than that of the first portion. The elastic element (72) is arranged between the radially outer surface of the second leg (712) of the swing rod (71) and the radially inner surface of the circumferential sidewall of the first inner push rod (33) located at the second part (3343) of the third through slot (334), and is able to bias the second leg (712) of the swing rod (71) in the radially inner direction toward the position that radially interferes with the storage container (4).

50. The holding device according to claim 49, characterized in that, The operable component can engage the first leg (711) of the lever (71) to allow the first leg (711) of the lever (71) to move radially inward when the operator presses the operable component, so that the lever (71) overcomes the biasing force of the elastic element (72) and pivots about the pin to the protrusion (713) of the second leg (712) of the lever (71) without interfering with the position of the storage container (4).

51. The holding device according to claim 50, characterized in that, The second portion (3343) of the third through slot (334) includes a bottom wall (3344) configured such that when the second leg (712) of the rocker arm (71) is in the first state, the distal end of the second leg (712) can overlap the bottom wall (3344), and The bottom wall (3344) does not contact the protrusion (713) of the swing arm (71).

52. The holding device according to claim 47, characterized in that, The first leg (711) and the second leg (712) of the swing arm (71) extend substantially parallel to each other.

53. The holding device according to claim 46, characterized in that, The first leg (711') of the lever (71') is capable of switching from a first state of radially interfering with the storage container (4) to a second state of not interfering with the storage container (4) in response to the operation of the operable component being pressed by the operator to move from the locked position to the unlocked position, and The proximal end of the first leg (711') of the swing arm (71') is configured to radially interfere with the storage container (4) when the first leg (711') of the swing arm (71') is in a first state, and to not interfere with the storage container (4) when the first leg is in a second state.

54. The holding device according to claim 53, characterized in that, The elastic element (72') is configured to bias the second leg (712') of the rocker arm (71') toward the radially outward direction, such that the rocker arm (71') pivoting about the pin can radially interfere with the position of the storage container (4) at the proximal end of the first leg (711') of the rocker arm.

55. The holding device according to claim 54, characterized in that, The through slot of the first internal push rod for receiving and holding the rocker arm is a fourth through slot (335), which includes a first portion (3352) on the proximal side and a second portion (3353) on the distal side. The first portion (3352) of the fourth through slot (335) allows the first leg (711') of the rocker arm (71') to pass through and radially interfere with the storage container (4), and The second part (3353) of the fourth through groove (335) is provided with a bottom wall, and the elastic element (72') is held between the bottom wall and the radially inner surface of the second leg (712') of the rocker arm (71').

56. The holding device according to claim 55, characterized in that, The operable component can engage the second leg (712') of the lever (71') such that when the operator presses the operable component, the second leg (712') of the lever (71') can overcome the biasing force of the elastic element (72') and move radially inward, so that the lever (71') pivots about the pin to the proximal end of the first leg (711') of the lever (71') without interfering with the position of the storage container (4).

57. The holding device according to claim 53, characterized in that, The first leg (711') and the second leg (712') of the swing arm (71') form an obtuse angle in the radially inward direction.

58. The holding device according to claim 44, characterized in that, One or more through slots are provided in the circumferential sidewall of the first internal push rod (33) along the circumferential direction, and each through slot accommodates and holds the rocker arm and the elastic element.

59. The holding device according to claim 43, characterized in that, The elastic element is a tension spring.

60. The holding device according to claim 3, characterized in that, The operable component is arranged on the outer housing (32) and is configured as a press-operated component. The limiting mechanism is configured to respond to movement of the operable component in a vertical radial direction between a locked position and an unlocked position, and to move in a vertical radial direction between an upper first position and a lower second position. The blocking mechanism is configured to switch between a closed blocking state and an open non-blocking state in response to the movement of the limiting mechanism between a first position and a second position.

61. The holding device according to claim 60, characterized in that, The limiting mechanism includes a retaining ring (921) that can be engaged by the operable component, such that the retaining ring moves downward when the operator presses down on the operable component.

62. The holding device according to claim 61, characterized in that, The retaining ring (921) can be fitted over the storage container (4) on its radial outer side. The retaining ring (921) includes a top (9211) that can be engaged by the operable component and two integrally arc-shaped arms extending from the top toward both sides. The end (9213) of each of the two arms away from the top includes a guide groove (9214) for engaging the blocking mechanism and guiding its movement. The guide groove (9213) extends in a horizontal radial direction.

63. The holding device according to claim 62, characterized in that, The first internal push rod (33) has a groove (339) for receiving the retaining ring (921), the groove matching the shape of the retaining ring so that the retaining ring can move in the groove between a first position and a second position in a vertical radial direction. The slot includes two guide portions (337) extending in a vertical radial direction, each guide portion receiving one of the two ends of the two arms of the retaining ring (921) away from the top, and allowing that end to move up and down in the vertical radial direction therein.

64. The holding device according to claim 63, characterized in that, The slot (339) of the first internal push rod includes a first tongue (336) extending distally from a proximal surface of the slot in a direction perpendicular to the axial direction, the first tongue being located below (9211) the top of the retaining ring (921).

65. The holding device according to claim 64, characterized in that, The limiting mechanism further includes an elastic element that abuts against a hole (9212) on the bottom surface of the top of the retaining ring (921) and the top surface of the first tongue (336), and is configured to bias the retaining ring (921) upward.

66. The holding device according to claim 65, characterized in that, The blocking mechanism includes two swing arms (9221) that are generally arc-shaped, each swing arm being pivotally connected to the first internal push rod (33) through its bottom end.

67. The holding device according to claim 66, characterized in that, A guide pin (9223) is provided at approximately the middle position of each swing arm. This guide pin can move along the guide groove (9213) of the arm portion on the same side of the retaining ring (921). When the retaining ring (921) is in the first position above, each guide pin (9223) is located at the radially inner end of the corresponding guide groove (9213), causing the two swing arms (9221) to form a closed blocking state. In the blocking state, the two swing arms radially interfere with the storage container; and When the operator presses the operable component to move the retaining ring (921) downward to the second position, the retaining ring (921) drives the corresponding guide pin (9223) to move to the radially outer end of each guide groove (9213) through each guide groove (9213), so that the two swing arms (9221) move radially outward to jointly form an open non-blocking state. In the non-blocking state, the two swing arms do not interfere with the storage container.

68. The holding device according to claim 67, characterized in that, The retaining device further includes an annular limiting element (923) for limiting the axial position of the blocking mechanism and the limiting mechanism.

69. The holding device according to claim 68, characterized in that, The limiting element (923) is located on the far side of the blocking mechanism and the limiting mechanism to prevent the blocking mechanism and the limiting mechanism from moving away from the first internal push rod (33) on the far side.

70. The holding device according to claim 69, characterized in that, The blocking mechanism is located on the far side of the limiting mechanism. The limiting element (923) includes: An annular flange (9231) extending proximally, the annular flange being able to abut the two swing arms (9221) distally; and A second tongue (9232) extending proximally beyond the annular flange (9231) is capable of abutting the top (9211) of the retaining ring (921) distally when the retaining ring (921) is in the first position above.

71. A needle-free injector (1), the needle-free injector comprising an injector body (3) and a storage container (4) located within an outer housing (32) of the injector body, the storage container being removably mounted in the needle-free injector. in, The syringe body (3) includes: the outer shell (32) and a tubular first internal plunger (33) within the outer shell, characterized in that the needleless syringe further includes: The retaining device for the storage container according to any one of claims 1-70, the retaining device being configured to prevent the storage container from being installed into the needleless injector and to prevent the storage container from being removed from the needleless injector in a locked state, and to allow the storage container to be installed into or removed from the needleless injector in an unlocked state.

72. The needleless injector (1) according to claim 71, characterized in that, The needleless injector also includes an injection head (2) that can be removably mounted to the injector body, the distal end of the injection head including an injection micropore.

73. The needleless injector (1) according to claim 71, characterized in that, The storage container (4) is a cartridge bottle.

74. The needleless injector (1) according to claim 71, characterized in that, The linkage mechanism is held by a tubular first internal push rod (33) within the outer housing (32) of the syringe body, and the storage container can be accommodated inside the first internal push rod (33). The first internal push rod (33) includes a first cutout (331) formed on the circumferential sidewall, and the outer housing (32) includes a second cutout (322) aligned with the first cutout in the circumferential direction. The first cutout (331) and the second cutout (322) together form a viewing window for the operator to observe the storage container.

75. The needleless injector (1) according to claim 74, characterized in that, The operable component (51) can be mounted on a recess (321) in the circumferential sidewall of the outer shell (32) of the syringe body (3), and the first hollow portion (331) and the second hollow portion (322) have elongated shapes extending along the axial direction (X), and The second hollow portion is located near the recessed portion (321).

76. The needleless injector (1) according to claim 75, characterized in that, The needleless injector (1) also includes a cap (6) that engages with the outer housing (32) of the needleless injector to cover the recess (321) and the second cutout (322), and The cover (6) includes a window (61) through which the operator engagement portion of the operable component can be exposed to the operator when the cover is closed on the outer housing (32).

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